General features

Gene IDMYPE6860
TypeCDS
From883159
To882695
Strand-
General namedhfR
Definitiondihyrofolate reductase
nt length465
aa length154
m.w.18274.69
COG[H] Coenzyme metabolism


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
mpneMPN300 dyr Segregation and condensation protein A 353535:3550551038.6e-25
mgengi|12045083 dihydrofolate reductase (dhfR) [Mycoplasma genitalium]961.0e-22
mpulgi|15829008 DIHYDROFOLATE REDUCTASE [Mycoplasma pulmonis]1114.9e-27
mmobgi|47458870 dihydrofolate reductase [Mycoplasma mobile 163K]953.0e-22
uuregi|13357671 dihyrofolate reductase [Ureaplasma urealyticum]1223.0e-30
phytgi|39938780 dihydrofolate reductase [Onion yellows phytoplasma]779.4e-17
bsubgi|16079240 dihydrofolate reductase [Bacillus subtilis]851.0e-18
cacegi|15896256 Dihydrofolate reductase [Clostridium acetobutylicum]951.2e-21
ecoligi|16128042 dihydrofolate reductase type I, trimethoprim resistance [Escherichia coli K12]774.0e-16

*mpne, Mycoplasma pneumoniae; mgen, Mycoplasma genitalium; mpul, Mycoplasma pulmonis; mmob, Mycoplasma mobile; uure, Ureaplasma urealyticum; phyt, ; bsub, Bacillus subtilis; cace, Clostridium acetobutylicum; ecoli, Escherichia coli K-12;

Pfam search result


ModelNo.DescriptionPosition (aa)ScoreE-value

DHFR_11Dihydrofolate reductase1-153109.21.4e-29

BLAST search result (top 10 hits)

IDDescriptionScoreE-value
gi|26554140dihyrofolate reductase [Mycoplasma penetrans HF-2] 7127.1e-74
gi|31544607Dyr [Mycoplasma gallisepticum R] 2762.2e-23
gi|56757670Segregation and condensation protein A 2762.2e-23
gi|185178818dihydrofolate reductase [Ureaplasma urealyticum serovar 11 str. ATCC 33695] 2611.5e-21
gi|171920664dihydrofolate reductase [Ureaplasma urealyticum serovar 9 str. ATCC 33175] 2592.3e-21
gi|188592545dihydrofolate reductase [Ureaplasma urealyticum serovar 10] 2555.9e-21
gi|171920488dihydrofolate reductase [Ureaplasma parvum serovar 1 str. ATCC 27813] 2548.1e-21
gi|13357671dihydrofolate reductase [Ureaplasma parvum serovar 14 str. ATCC 33697] 2548.6e-21
gi|116492832dihydrofolate reductase [Pediococcus pentosaceus ATCC 25745] 2549.0e-21
gi|186701911dihydrofolate reductase [Ureaplasma parvum serovar 6 str. ATCC 27818] 2531.2e-20


Maintained by Jun Ishikawa