>gi|26553573|ref|NP_757507.1| endonuclease IV [Mycoplasma penetrans HF-2] >gi|26453579|dbj|BAC43911.1| endonuclease IV [Mycoplasma penetrans HF-2] (311 aa)
Score = 1591, Expect = 3.7e-175, Identities = 310/311 (99%), Positives = 311/311 (100%)
  Q:     1 VLLLFLSFWLIQWLFLKTKEMCMSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +LLLFLSFWLIQWLFLKTKEMCMSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE
  S:     1 MLLLFLSFWLIQWLFLKTKEMCMSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
>gi|39931147|sp|Q8EWT2|END4_MYCPE Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) (289 aa)
Score = 1469, Expect = 4.8e-161, Identities = 289/289 (100%), Positives = 289/289 (100%)
  Q:    23 MSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           MSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE
  S:     1 MSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 289
>gi|162447345|ref|YP_001620477.1| endodeoxyribonuclease IV [Acholeplasma laidlawii PG-8A] >gi|189037118|sp|A9NFH1|END4_ACHLI Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|161985452|gb|ABX81101.1| endodeoxyribonuclease IV [Acholeplasma laidlawii PG-8A] (294 aa)
Score = 687, Expect = 2.0e-70, Identities = 138/274 (50%), Positives = 191/274 (69%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN-DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID-ISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           L+LGSHV  K  +   GSVLE LEY+ N  MV+TG PQN +RK ++   I+EA  LMKEK  + L ++VVHAPY+INL +P    R+  +  L  E+ R  Q+    +VLHPGSA+  +R  A+  I++ LN+ I+ T + +V I +ETMAGKG+E+G  FEE+  I+ GV +K R+ VC DTCH+HD+G D I D D+TL+ F   + L+YI V+H+NDSKNE+G+ KDRH+NIG+G +G+D L+K  ++E    +PKILETPY +DKP YK EI
  S:     2 LILGSHVSLKGNDMFYGSVLEALEYNANTMMVYTGAPQNTIRKPIETMKIEEAHALMKEKG-IDLNHVVVHAPYIINLCNPDPERRAFAVEFLTKEVIRVGQMGINQMVLHPGSAVGGNREEAVQWISEGLNQIIDNTKSYNVRIALETMAGKGNEIGKTFEEIKAIIDGVDDKSRVSVCFDTCHVHDAGYDVIHDLDKTLQLFDDIVGLNYISVVHVNDSKNELGASKDRHENIGFGYIGYDALLKVIYHEAFKEIPKILETPYVNDKPPYKLEI 276
>gi|188568606|ref|ZP_02828485.2| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 2] (304 aa)
Score = 654, Expect = 1.6e-66, Identities = 138/287 (48%), Positives = 191/287 (66%)
  Q:    23 MSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGI--DISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRD--DKPI--YKQEIINLNSKEW 309
           M K  L++GSHV  KA ++  GSV E L Y  N  MV+TG PQN  R+ ++   I+EA  L+KE N + L N++VHAPY+IN  S K+  R L    LI EI RT  +    IVLHPGS LD D ++A+  +   LN+     + +V++C+ETM+GKGSE+GIN +++  I+  V +KK IGVCLDTCHM DSGI  D    +Q L+EF   + + YIKV+H+NDSKN  G+ KDRH+N+GYG +GFD L+   ++  L N+PKILETP+ D  D+ I  Y+ EI  +  ++W
  S:     1 MDKYNLIIGSHVSLKANDFFYGSVKEALSYGANTLMVYTGAPQNTRRQPIELFKINEAHNLLKEHN-IDLNNLIVHAPYIINPCSSKKYVRELAKEFLIQEIERTQSMGITKIVLHPGSCLDQDEDIALKQVYTMLNEIFATINTNVVVCLETMSGKGSEIGINLKQLKTIIDNVDSKKNIGVCLDTCHMSDSGIALDHDSFNQYLKEFDAQIGIDYIKVLHINDSKNPRGANKDRHENLGYGTIGFDNLINIIYHPLLNNIPKILETPWFDFHDQSISLYEYEIKMIRDRKW 292
>gi|171920987|ref|ZP_02696376.2| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 13 str. ATCC 33698] >gi|185179170|ref|ZP_02555813.2| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 5 str. ATCC 27817] >gi|188024324|ref|ZP_02570284.2| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 7 str. ATCC 27819] >gi|188039445|ref|ZP_02528408.2| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 8] >gi|188518632|ref|ZP_02557001.2| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 11 str. ATCC 33695] >gi|188524484|ref|ZP_02558391.2| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 12 str. ATCC 33696] >gi|188531083|ref|ZP_02547192.2| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 4 str. ATCC 27816] >gi|188592417|ref|ZP_02693831.2| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 10] >gi|195867585|ref|ZP_03079587.1| apurinic endonuclease Apn1 [Ureaplasma urealyticum serovar 9 str. ATCC 33175] >gi|171903018|gb|EDT49307.1| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 13 str. ATCC 33698] >gi|184208905|gb|EDU05948.1| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 5 str. ATCC 27817] >gi|188019003|gb|EDU57043.1| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 7 str. ATCC 27819] >gi|188997795|gb|EDU66892.1| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 11 str. ATCC 33695] >gi|195659650|gb|EDX53030.1| apurinic endonuclease (APN1) [Ureaplasma urealyticum serovar 12 str. ATCC 33696] >gi|195660642|gb|EDX53897.1| apurinic endonuclease Apn1 [Ureaplasma urealyticum serovar 9 str. ATCC 33175] (304 aa)
Score = 651, Expect = 3.2e-66, Identities = 138/287 (48%), Positives = 191/287 (66%)
  Q:    23 MSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGI--DISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRD--DKPI--YKQEIINLNSKEW 309
           M K  L++GSHV  KA ++  GSV E L Y  N  MV+TG PQN  R+ ++   I+EA  L+KE N + L N++VHAPY+IN  S K+  R L    LI EI RT  +    IVLHPGS LD D ++A+  +   LN+     + +V++C+ETM+GKGSE+GIN +++  I+  V +KK IGVCLDTCHM DSGI  D    +Q L+EF   + + YIKV+H+NDSKN  G+ KDRH+N+GYG +GFD L+   ++  L N+PKILETP+ D  D+ I  Y+ EI  +  ++W
  S:     1 MDKYNLIIGSHVSLKANDFFYGSVKEALSYGANTLMVYTGAPQNTRRQPIELFKINEAHNLLKEHN-IDLNNLIVHAPYIINPCSSKKYVRELAKEFLIQEIERTQFMGITKIVLHPGSCLDQDEDIALKQVYTMLNEIFATINTNVVVCLETMSGKGSEIGINLKQLKTIIDNVDSKKNIGVCLDTCHMSDSGIALDHDSFNQYLKEFDAQIGIDYIKVLHINDSKNPRGANKDRHENLGYGTIGFDNLINIIYHPLLNNIPKILETPWFDFHDQSISLYEYEIKMIRDRKW 292
>gi|169351092|ref|ZP_02868030.1| hypothetical protein CLOSPI_01871 [Clostridium spiroforme DSM 1552] >gi|169292154|gb|EDS74287.1| hypothetical protein CLOSPI_01871 [Clostridium spiroforme DSM 1552] (286 aa)
Score = 646, Expect = 1.4e-65, Identities = 135/274 (49%), Positives = 184/274 (67%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           +L+GSHV    K  L+GSV E L Y+   FM +TG PQN  RK +DQ  ++EA +LM+E N + + N+VVHAPY+INL +  KE T  + +  L  EI R   I    +VLHPGS + +   V +N I + LN+A +   N V I +ETMAGKGSE G +F+E+  I+  V N + +GVCLDTCH+HD+G D++D D  L+EF + + L+ + V+H+NDSKN  G+ KDRH+NIGYG +GF+ L K  H+EKL +VPKILETPY +    YKQEI
  S:     1 MLIGSHVSMSGKEMLLGSVKEALSYNATTFMFYTGAPQNTARKPIDQLRVEEAKQLMEE-NGIDINNVVVHAPYIINLANTIKEETYEIAVRFLKQEIERCKAIGITRLVLHPGSHVKAGSQVGLNRIIEGLNEATKDCGN-VKIALETMAGKGSECGRSFDEIKYIIDNVDNNECLGVCLDTCHLHDAGYDLNDFDSVLDEFDQKIGLNRLLVVHINDSKNVRGASKDRHENIGYGYIGFEVLNKIVHHEKLKDVPKILETPYIEKVAPYKQEI 273
>gi|167755661|ref|ZP_02427788.1| hypothetical protein CLORAM_01176 [Clostridium ramosum DSM 1402] >gi|167704600|gb|EDS19179.1| hypothetical protein CLORAM_01176 [Clostridium ramosum DSM 1402] (286 aa)
Score = 642, Expect = 3.5e-65, Identities = 131/274 (47%), Positives = 181/274 (66%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           +++GSHV    K  L+GSV E L Y  N FM +TG PQN  RK +DQ  I+EA +LMKE N + ++N+VVHAPY+INL  + K  T  L ++ L  EI R   I +  +VLHPG+ + +   + +  I + LN+A +   N V I +ETMAGKGSE G  F+E+  I+  V N + +GVC+DTCH+HD+G D++  D  L EF + + L  + V+H+NDSKNE G+ KDRH+NIGYG +GFD L    H++KL +VPKILETPY +    YK+EI
  S:     1 MIIGSHVSMSGKEMLLGSVKEALSYGANTFMFYTGAPQNTARKPIDQLRIEEAKELMKE-NGIEIDNVVVHAPYIINLANTTKPETFELAVSFLKQEIERCKAIGATRLVLHPGAHVGAGSQIGLERIVEGLNEATKDCGN-VKIALETMAGKGSECGRTFDELQYIIENVDNNECLGVCMDTCHLHDAGFDLTKFDDILTEFDQKIGLERLLVVHVNDSKNECGASKDRHENIGYGHIGFDTLNMIVHHDKLKSVPKILETPYIEKIAPYKEEI 273
>gi|13357866|ref|NP_078140.1| endonuclease IV [Ureaplasma parvum serovar 3 str. ATCC 700970] >gi|10719985|sp|Q9PQI5|END4_UREPA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|11263362|pir||A82907 endonuclease IV UU306 [imported] - Ureaplasma urealyticum >gi|6899282|gb|AAF30715.1|AE002128_3 endonuclease IV [Ureaplasma parvum serovar 3 str. ATCC 700970] (303 aa)
Score = 640, Expect = 5.8e-65, Identities = 133/287 (46%), Positives = 193/287 (67%)
  Q:    23 MSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSG--IDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK----PIYKQEIINLNSKEW 309
           M K  L++GSHV  KAK++  GSV E L Y  N FMV+TG PQN  R+ +    I+EA  L+K+ N + L++++VHAPY+IN  S K++ R L    LI EI RT  +    +VLHPGS L+ + ++A+  +   LN      + +VI+C+ETMAGKGSE+G+N +++  I+  V +KK IGVCLDTCHM+DSG  +D  + +Q L+EF   + ++YIKV+H+NDSKN  G+ KDRH+N+GYG +GF  L+   ++  L N+PKILETP+ +      P+YK EI  +   +W
  S:     1 MDKYNLIIGSHVSLKAKDFFYGSVKEALSYGSNTFMVYTGAPQNTKRQPIKSFKIEEAHNLLKKHN-INLDDLIVHAPYIINPCSSKKNVRELAKEFLIQEIQRTESMGITKLVLHPGSRLEQNEDIALEQVYTMLNDIFSTINTNVIVCLETMAGKGSEIGVNIKQLKTIIDNVHSKKNIGVCLDTCHMNDSGLILDYYNFNQYLKEFDAQIGINYIKVLHINDSKNPCGANKDRHENLGYGTIGFANLINIIYHPLLNNIPKILETPWFNVNDELIPLYKHEIKMIRDCKW 292
>gi|169836036|ref|ZP_02869224.1| endonuclease IV [candidate division TM7 single-cell isolate TM7a] (307 aa)
Score = 639, Expect = 7.9e-65, Identities = 140/289 (48%), Positives = 197/289 (68%)
  Q:    23 MSKNKLL-LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY---RDDK-----PIYKQEIINLNSKEWKE 311
           MSK ++  +GSHVG   K+ L+GSV E + Y  N FM++TG PQN  RK +++  I+  +KLM E N + + +IVVHAPY+INLG+  K  T  + +  L  EI RT+ I +  IVLHPG+ +     V IN I + LN+ +   +    + +ETMAGKG+E G +FEE++KI+ GVK K ++ VC DTCH+HD+G DI +D +  +E+F K + +  I VIHLNDSKN +G+ KDRH+NIG+G +GF+ L K AH EK +++PKILETPY    DDK     P YK EI  L + ++ E
  S:     1 MSKKEIFKIGSHVGMSGKDMLLGSVKEAVSYGSNTFMIYTGAPQNTRRKPIEELNIEAGLKLMGE-NGIDINDIVVHAPYIINLGNTVKPETFEIAVQFLRTEIERTDAIGAPRIVLHPGAHVGEGAEVGINKIIEGLNEVL-TKEQKTTVALETMAGKGTECGRSFEEIAKIIDGVKLKDKLSVCFDTCHVHDAGYDIVNDFEGVIEQFDKIVGIDRISVIHLNDSKNPVGAHKDRHENIGFGYIGFEVLNKIAHFEKFSHLPKILETPYVALSDDKKAKKVPPYKFEIEMLRAGKFDE 298
>gi|167971869|ref|ZP_02554146.1| apurinic endonuclease (APN1) [Ureaplasma parvum serovar 6 str. ATCC 27818] >gi|168282510|ref|ZP_02690177.1| apurinic endonuclease (APN1) [Ureaplasma parvum serovar 14 str. ATCC 33697] >gi|168308664|ref|ZP_02691339.1| apurinic endonuclease (APN1) [Ureaplasma parvum serovar 1 str. ATCC 27813] >gi|170762414|ref|YP_001752388.1| apurinic endonuclease (APN1) [Ureaplasma parvum serovar 3 str. ATCC 27815] >gi|168827991|gb|ACA33253.1| apurinic endonuclease (APN1) [Ureaplasma parvum serovar 3 str. ATCC 27815] >gi|171902969|gb|EDT49258.1| apurinic endonuclease (APN1) [Ureaplasma parvum serovar 1 str. ATCC 27813] >gi|182675662|gb|EDT87567.1| apurinic endonuclease (APN1) [Ureaplasma parvum serovar 14 str. ATCC 33697] >gi|186700823|gb|EDU19105.1| apurinic endonuclease (APN1) [Ureaplasma parvum serovar 6 str. ATCC 27818] (306 aa)
Score = 639, Expect = 8.0e-65, Identities = 133/287 (46%), Positives = 193/287 (67%)
  Q:    23 MSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSG--IDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK----PIYKQEIINLNSKEW 309
           M K  L++GSHV  KAK++  GSV E L Y  N FMV+TG PQN  R+ +    I+EA  L+K+ N + L++++VHAPY+IN  S K++ R L    LI EI RT  +    +VLHPGS L+ + ++A+  +   LN      + +VI+C+ETMAGKGSE+G+N +++  I+  V +KK IGVCLDTCHM+DSG  +D  + +Q L+EF   + ++YIKV+H+NDSKN  G+ KDRH+N+GYG +GF  L+   ++  L N+PKILETP+ +      P+YK EI  +   +W
  S:     4 MDKYNLIIGSHVSLKAKDFFYGSVKEALSYGSNTFMVYTGAPQNTKRQPIKSFKIEEAHNLLKKHN-INLDDLIVHAPYIINPCSSKKNVRELAKEFLIQEIQRTESMGITKLVLHPGSRLEQNEDIALEQVYTMLNDIFSTINTNVIVCLETMAGKGSEIGVNIKQLKTIIDNVHSKKNIGVCLDTCHMNDSGLILDYYNFNQYLKEFDAQIGINYIKVLHINDSKNPCGANKDRHENLGYGTIGFANLINIIYHPLLNNIPKILETPWFNVNDELIPLYKHEIKMIRDCKW 295
>gi|167745762|ref|ZP_02417889.1| hypothetical protein ANACAC_00455 [Anaerostipes caccae DSM 14662] >gi|167654793|gb|EDR98922.1| hypothetical protein ANACAC_00455 [Anaerostipes caccae DSM 14662] (300 aa)
Score = 627, Expect = 2.1e-63, Identities = 131/274 (47%), Positives = 178/274 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY------RDDKPIYKQEI 301
           +L+GSHVG K K   +GSV E L Y  N FMV+TG PQN  RK++ +  I+EA  LM+E     +E+ VVHAPY+INLG+  K  T  L +  L +EI RT+ + S+ +VLHPG+ + +  +  I  I + LN+ +   D  V + +ETMAGKGSEVG NF+E+ +I  GVK   ++ VC DTCH  DSG+DI  D +  ++ F K +    I V H+NDSKN  G+ KDRH+NIG+G++GFD L    H+E    VPKILETPY      ++  P YK EI
  S:     1 MLIGSHVGMKGKEMFLGSVKEALSYGANTFMVYTGAPQNTRRKDISELRIEEAKALMEESG---IESFVVHAPYIINLGNTVKPETFELAVEFLALEIERTSAMGSRTLVLHPGAHVGAGEDAGIERIVEGLNEVL-TKDTPVFVALETMAGKGSEVGRNFDELKRIYDGVKYNDKLRVCFDTCHTSDSGLDIVGDFEGVMDSFDKAVGKEQIAVFHINDSKNPRGAAKDRHENIGFGEIGFDALNHIVHHEDFTQVPKILETPYIKEEGTKNSYPPYKYEI 278
>gi|160915044|ref|ZP_02077257.1| hypothetical protein EUBDOL_01052 [Eubacterium dolichum DSM 3991] >gi|158432843|gb|EDP11132.1| hypothetical protein EUBDOL_01052 [Eubacterium dolichum DSM 3991] (293 aa)
Score = 624, Expect = 4.4e-63, Identities = 126/279 (45%), Positives = 183/279 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGS-PKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           +++GSHV   A +Y++GSV E L Y  N  M++TG PQN  RK +++  + EA+ L+ E + +  E+I+VHAPY+INL +  K+ T  LG+  L  EI R   + +K +VLHPGS + +     +  I + L+ A+E    +V I +ETMAGKGSE+G NFE++  ++   K+  R+ VC+DTCH+HD+G D+SD D  LE F + + L  +  IH+NDSKN  G+RKDRH NIG+G++GFD L +  H+EKL +V KILETP+ D    YK EI  L +
  S:     1 MIIGSHVSMSAPDYVLGSVKEALSYGANALMLYTGAPQNTRRKAMEELKVKEALALLDEHH-IPHEHIIVHAPYIINLANCQKQETFELGVEFLRKEIERVKALGAKYLVLHPGSHVQAGEEAGLTRIVEGLDLAMENI-GEVEIAIETMAGKGSELGYNFEQIRYLMEHAKHGDRLRVCMDTCHLHDAGFDVSDFDAILEAFDRVISLERLVCIHVNDSKNVRGARKDRHANIGFGEIGFDALNRIVHHEKLQHVVKILETPWVDGVAPYKHEIAMLKA 278
>gi|31544574|ref|NP_853152.1| hypothetical protein MGA_1293 [Mycoplasma gallisepticum R] >gi|39930952|sp|Q7NBA9|END4_MYCGA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|31541419|gb|AAP56720.1| Nfo [Mycoplasma gallisepticum R] (303 aa)
Score = 620, Expect = 1.4e-62, Identities = 127/289 (43%), Positives = 190/289 (65%)
  Q:    23 MSKNKL-LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKN-PLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK-----PIYKQEIINLNSKEWKE 311
           M  NK+  LG  VG    ++++G V   ++Y    FM ++GPPQ+F R    Q  +D A   + + N   L +N VVHAPYLINL +   + R    N  + E+ RTN++ +K  VLHPGSAL+  D+  A++H+A  LN+AI  T  D IIC+ETMA KG ++   FEE+  ++  + +K RIGVC DTCH+HD+G D++   + ++ F + + L Y+ VIHLNDSKN +G+RKDRH NIGYGK+GF+ L+ + +++++ N   ILETP+ DD      P+YK+EI  + +K++ E
  S:     1 MKSNKIKYLGCFVGATKPDFMLGMVKTVVDYGATSFMFYSGPPQSFRRTPTAQFKLDLAKAYLAKHNLGDLGDNYVVHAPYLINLANGDSTKRERSFNFFLDELKRTNELGAKYFVLHPGSALNVKDKTQALDHLATELNRAISMT-KDTIICLETMADKGQQICSKFEELRYVIDQISDKSRIGVCFDTCHVHDAGYDLAKTQELIDHFDQVIGLKYLYVIHLNDSKNPMGARKDRHANIGYGKIGFENLLNFIYHKEICNKIIILETPWIDDPIRGEVPLYKEEIEMIRNKKFVE 296
>gi|15924547|ref|NP_372081.1| endonuclease IV [Staphylococcus aureus subsp. aureus Mu50] >gi|15927137|ref|NP_374670.1| endonuclease IV [Staphylococcus aureus subsp. aureus N315] >gi|21283238|ref|NP_646326.1| endonuclease IV [Staphylococcus aureus subsp. aureus MW2] >gi|49486393|ref|YP_043614.1| endonuclease IV [Staphylococcus aureus subsp. aureus MSSA476] >gi|148268041|ref|YP_001246984.1| endonuclease IV [Staphylococcus aureus subsp. aureus JH9] >gi|150394109|ref|YP_001316784.1| endonuclease IV [Staphylococcus aureus subsp. aureus JH1] >gi|156979875|ref|YP_001442134.1| endonuclease IV [Staphylococcus aureus subsp. aureus Mu3] >gi|166224291|sp|A7X2V2|END4_STAA1 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|189037129|sp|A6U229|END4_STAA2 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|189037130|sp|A5IT85|END4_STAA9 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|54037047|sp|P63538|END4_STAAN Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|54037048|sp|P63539|END4_STAAW Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|54040807|sp|P63537|END4_STAAM Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|56748969|sp|Q6G909|END4_STAAS Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|13701355|dbj|BAB42649.1| SA1386 [Staphylococcus aureus subsp. aureus N315] >gi|14247328|dbj|BAB57719.1| probable endonuclease IV [Staphylococcus aureus subsp. aureus Mu50] >gi|21204678|dbj|BAB95374.1| MW1509 [Staphylococcus aureus subsp. aureus MW2] >gi|49244836|emb|CAG43296.1| putative endonuclease [Staphylococcus aureus subsp. aureus MSSA476] >gi|147741110|gb|ABQ49408.1| Endonuclease IV [Staphylococcus aureus subsp. aureus JH9] >gi|149946561|gb|ABR52497.1| apurinic endonuclease Apn1 [Staphylococcus aureus subsp. aureus JH1] >gi|156722010|dbj|BAF78427.1| hypothetical protein [Staphylococcus aureus subsp. aureus Mu3] (296 aa)
Score = 617, Expect = 2.8e-62, Identities = 131/282 (46%), Positives = 189/282 (67%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEW 309
           +LLGSHV    K  L GS +E  EY    FM++TG PQN  RK ++   I +  ++M++     L NIVVHAPY+IN+  + K  T +LG++ L  EI RT  I +K IVLHPG+ + +  +  IN I + LN+ +   DN+V I +ETMAGKG+E+G +FEE+++I+ GV N +R+ VC DTCH HD+G ++  D D  L EF K + +  IKV+H+NDSKN+ G++KDRH+NIG+G +GFD L    H++   ++PKILETPY     ++ KP YK EI  L  +++
  S:     1 MLLGSHVSMSGKKMLEGSAIEAYEYGETTFMIYTGAPQNTRRKSIEDLNITKGHEVMEKYG---LSNIVVHAPYIINIANTTKPETFNLGVDFLQQEIERTQAIGAKDIVLHPGAHVGAGVDAGINKIIEGLNEVL-TNDNNVRIALETMAGKGTEIGRSFEELARIIDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSKNDRGAQKDRHENIGFGYIGFDALNYIVHHDSFKDIPKILETPYVGEDKKNKKPPYKLEIEMLKQQQF 285
>gi|149182025|ref|ZP_01860511.1| endonuclease IV [Bacillus sp. SG-1] >gi|148850290|gb|EDL64454.1| endonuclease IV [Bacillus sp. SG-1] (297 aa)
Score = 617, Expect = 3.4e-62, Identities = 132/282 (46%), Positives = 185/282 (65%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWKE 311
           LGSHV    K  L+GS  E + Y  N FM++TG PQN  RK+++   I+  +  MKE     ++ IVVHAPY+IN+G +   +T  LG+N L  EI RT  + +K IVLHPG+ + +     I  I + LN+ +   D +V I +ETMAGKGSE G +FEE++ I+ GV++  R+ VC DTCH HD+G DI +D D  L+EF + + +  IKV+H+NDSKN  G+ KDRH+NIG+G +GFD L +  H+ +L +VPKILETP+     ++ K  YK EI  L +K W E
  S:     4 LGSHVSMSGKKMLLGSSEEAVAYGANTFMIYTGAPQNTRRKKIEDLNIENGLLHMKENG---IDEIVVHAPYIINIGNTTNPATFELGVNFLQSEIERTAALGAKQIVLHPGAHVGAGAEAGIKKIIEGLNEVL-VKDQEVQIALETMAGKGSECGRSFEELAMIIEGVEHNDRLSVCFDTCHTHDAGYDIVNDFDGVLDEFDRIVGIDRIKVLHINDSKNVRGAAKDRHENIGFGHIGFDALARIVHHPQLTDVPKILETPFVGEDKKNKKAPYKFEIEMLKNKTWDE 288
>gi|57651950|ref|YP_186454.1| endonuclease IV [Staphylococcus aureus subsp. aureus COL] >gi|82751160|ref|YP_416901.1| endonuclease IV [Staphylococcus aureus RF122] >gi|87162016|ref|YP_494212.1| endonuclease IV [Staphylococcus aureus subsp. aureus USA300] >gi|88195365|ref|YP_500169.1| endonuclease IV [Staphylococcus aureus subsp. aureus NCTC 8325] >gi|151221672|ref|YP_001332494.1| endonuclease IV [Staphylococcus aureus subsp. aureus str. Newman] >gi|161509786|ref|YP_001575445.1| endonuclease IV [Staphylococcus aureus subsp. aureus USA300_TCH1516] >gi|168728537|ref|ZP_02760814.1| deoxyribonuclease IV (phage-T(4)-induced) [Staphylococcus aureus subsp. aureus USA300_TCH1516] >gi|122539415|sp|Q2FY16|END4_STAA8 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|123485650|sp|Q2FGG6|END4_STAA3 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|123547830|sp|Q2YT22|END4_STAAB Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|172048904|sp|A6QHA0|END4_STAAE Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|189037131|sp|A8Z497|END4_STAAT Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|71151863|sp|Q5HFK3|END4_STAAC Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|57286136|gb|AAW38230.1| endonuclease IV [Staphylococcus aureus subsp. aureus COL] >gi|82656691|emb|CAI81118.1| endonuclease IV [Staphylococcus aureus RF122] >gi|87127990|gb|ABD22504.1| endonuclease IV [Staphylococcus aureus subsp. aureus USA300_FPR3757] >gi|87202923|gb|ABD30733.1| endonuclease IV, putative [Staphylococcus aureus subsp. aureus NCTC 8325] >gi|150374472|dbj|BAF67732.1| endonuclease IV [Staphylococcus aureus subsp. aureus str. Newman] >gi|160368595|gb|ABX29566.1| deoxyribonuclease IV (phage-T(4)-induced) [Staphylococcus aureus subsp. aureus USA300_TCH1516] (296 aa)
Score = 615, Expect = 5.8e-62, Identities = 131/282 (46%), Positives = 189/282 (67%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEW 309
           +LLGSHV    K  L GS +E  EY    FM++TG PQN  RK ++   I +  ++M++     L NIVVHAPY+IN+  + K  T +LG++ L  EI RT  I +K IVLHPG+ + +  +  IN I + LN+ +   DN+V I +ETMAGKG+E+G +FEE+++I+ GV N +R+ VC DTCH HD+G ++  D D  L EF K + +  IKV+H+NDSKN+ G++KDRH+NIG+G +GFD L    H++   ++PKILETPY     ++ KP YK EI  L  +++
  S:     1 MLLGSHVSMSGKKMLEGSAIEAHEYGETTFMIYTGAPQNTRRKSIEDLNITKGHEVMEKYG---LSNIVVHAPYIINIANTTKPETFNLGVDFLQQEIERTQAIGAKDIVLHPGAHVGAGVDAGINKIIEGLNEVL-TNDNNVRIALETMAGKGTEIGRSFEELARIIDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSKNDRGAQKDRHENIGFGYIGFDALNYIVHHDSFKDIPKILETPYVGEDKKNKKPPYKLEIEMLKQQQF 285
>gi|171323288|ref|ZP_02911808.1| apurinic endonuclease Apn1 [Geobacillus sp. WCH70] >gi|171090482|gb|EDT36775.1| apurinic endonuclease Apn1 [Geobacillus sp. WCH70] (298 aa)
Score = 612, Expect = 1.1e-61, Identities = 131/284 (46%), Positives = 185/284 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKE-STRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP-DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWKE 311
           L +GSHV    K  L+ +  E + Y  N FM++TG PQN  RK++++  I+  +  MKE     +E IVVHAPY+IN+G+ K   T +LG+  L  EI RT  I +K IVLHPG+ + +     I  I + LN+ +   +  V I +ETMAGKGSE G +FEE+++I+ GV + +++ VC DTCH HD+G +I D  D  LEEF + + L  +KV+H+NDSKN  GSRKDRH+NIG+G +GF  L    H+ +LA++PKILETPY      + KP YK EI  L ++ + E
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGANTFMIYTGAPQNTRRKKIEELNIEAGLAHMKEHG---IEEIVVHAPYIINIGNTKNPDTFALGVEFLRSEIERTEAIGAKQIVLHPGAHVGAGPEAGIRKIIEGLNEVL-TREQTVQIALETMAGKGSECGRSFEELAQIIDGVTHNEKLSVCFDTCHTHDAGYNIVDDFDGVLEEFDRIIGLDRLKVLHINDSKNPRGSRKDRHENIGFGHIGFAALNYIVHHPQLADIPKILETPYVGEDKNNKKPPYKHEIAMLRAQVFDE 288
>gi|49483806|ref|YP_041030.1| endonuclease IV [Staphylococcus aureus subsp. aureus MRSA252] >gi|56749023|sp|Q6GGE2|END4_STAAR Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|49241935|emb|CAG40629.1| putative endonuclease [Staphylococcus aureus subsp. aureus MRSA252] (296 aa)
Score = 612, Expect = 1.2e-61, Identities = 131/282 (46%), Positives = 188/282 (66%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEW 309
           +LLGSHV    K  L GS +E  EY    FM++TG PQN  RK ++   I +  ++M++     L NIVVHAPY+IN+  + K  T +LG++ L  EI RT  I +K IVLHPG+ + +  +  IN I + LN+ +   DN+V I +ETMAGKG+E+G +FEE+++I+ GV N +R+ VC DTCH HD+G ++  D D  L EF K + +  IKV+H+NDSKN+ G++KDRH+NIG+G +GFD L    H++   ++PKILETPY     ++ KP YK EI  L  + +
  S:     1 MLLGSHVSMSGKKMLEGSAIEAHEYGETTFMIYTGAPQNTRRKSIEDLNITKGHEVMEKYG---LSNIVVHAPYIINIANTTKPETFNLGVDFLQQEIERTQAIGAKDIVLHPGAHVGAGVDAGINKIIEGLNEVL-TNDNNVRIALETMAGKGTEIGRSFEELARIIDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSKNDRGAQKDRHENIGFGYIGFDALNYIVHHDSFKDIPKILETPYVGEDKKNKKPPYKLEIEMLKQQHF 285
>gi|192810196|ref|ZP_03038869.1| apurinic endonuclease Apn1 [Geobacillus sp. Y412MC10] >gi|192800488|gb|EDV76995.1| apurinic endonuclease Apn1 [Geobacillus sp. Y412MC10] (373 aa)
Score = 610, Expect = 2.2e-61, Identities = 128/274 (46%), Positives = 177/274 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATD-NDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEI 301
           L +GSHV F  K  L  +  E   Y  + FM++TG PQN  RK +D   I+E    MKE     +E IVVHAPY+INLGS K +T  L ++ L  EI RT+ +  K IVLHPG+  D D    I+ IA+ LN+ +  TD  +V I +ETMAGKG+E+G +FEE++ I+  VK   R+ +CLDTCH+HD+G DI +D D  LE+F K + L  + V+H+NDSKN  G+ KDRH  IG G +G++ + +  H+EKL   P ILETP+     +  +P+Y+ EI
  S:     2 LKIGSHVSFSDKGLLTATA-EATSYGSSSFMIYTGAPQNTRRKPIDSMFIEEGKAAMKESG---IEEIVVHAPYIINLGSYKPNTFELAVSFLQEEIRRTHAVGVKNIVLHPGAYTDKDAEYGIDRIAEGLNEVLGGTDETEVKIALETMAGKGTEMGRSFEEIASIIDKVKYNDRLAICLDTCHIHDAGYDIVNDLDGVLEQFDKLIGLDRLTVVHVNDSKNPRGAGKDRHTPIGTGWIGYEAIQRVVHHEKLQGRPFILETPWIGKDPKTQRPMYEIEI 278
>gi|124523775|ref|ZP_01697700.1| apurinic endonuclease Apn1 [Bacillus coagulans 36D1] >gi|124495342|gb|EAY43058.1| apurinic endonuclease Apn1 [Bacillus coagulans 36D1] (299 aa)
Score = 609, Expect = 2.5e-61, Identities = 129/284 (45%), Positives = 185/284 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP-DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWKE 311
           L +GSHV    K  L+ S  E + Y  N FM++TG PQN  RK+++   I+  +  MKE     +E IVVHAPY+IN+G +   +T  LG+  L  EI RT  I +K IVLHPG+ + +    AI  I + LN+ +   +  V I +ETMAGKGSE G  FEE+++I+ GVK   ++ VC DTCH HD+G D+ +  D+ L+EF + + +  +KV+H+NDSKNE GS KDRH+NIG+G +GF+ L    H+  L+++PKILETPY     ++ KP YK EI  L ++++ E
  S:     2 LKIGSHVSMSGKKMLLASSEEAVSYGANTFMIYTGAPQNTRRKKIEDLNIEAGLAHMKEHG---IEEIVVHAPYIINIGNTTNPATFELGVRFLRSEIERTEAIGAKQIVLHPGAHVGAGPEKAIKKIIEGLNEVL-VPEQTVQIALETMAGKGSECGRTFEELAEIIDGVKYNDKLSVCFDTCHTHDAGYDVKNRFDEVLDEFDRIIGIGRLKVLHVNDSKNEAGSHKDRHENIGFGHIGFEALDYIVHHPALSDIPKILETPYVGEDKKNRKPPYKYEIAMLRNRKFDE 288
>gi|154686774|ref|YP_001421935.1| endonuclease IV [Bacillus amyloliquefaciens FZB42] >gi|166224271|sp|A7Z6S8|END4_BACA2 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|154352625|gb|ABS74704.1| YqfS [Bacillus amyloliquefaciens FZB42] (297 aa)
Score = 609, Expect = 2.6e-61, Identities = 130/284 (45%), Positives = 188/284 (66%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDIS-DPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWKE 311
           L +GSHV    K+ L+ +  E + Y  N FM++TG PQN  RK+++   I+     MKE     ++ IVVHAPY+IN+G +   +T  LG++ L  EI RT  I ++ IVLHPG+ + +     I  I + LN+ I    N V I +ETMAGKGSE G +FEE+++I++GV + + + VC DTCH HD+G D++ D D  L EF K + +  IKV+H+NDSKN  G+RKDRH+NIG+G++GFD L    H+E+LA++PKILETPY     ++ KP Y+ EI  L  K++ +
  S:     2 LKIGSHVSMSGKHMLLAASKEAVSYGANTFMIYTGAPQNTRRKKIEDLNIEAGRAHMKENG---IDEIVVHAPYIINIGNTTNPATFELGVDFLRSEIERTAAIGARQIVLHPGAHVGAGAETGIKKIIEGLNEVIVPGQN-VQIALETMAGKGSECGRSFEELAEIIAGVTHNEHLSVCFDTCHTHDAGYDVANDFDGVLNEFDKIVGIDRIKVLHVNDSKNIKGARKDRHENIGFGEIGFDALQYIVHHEQLADIPKILETPYVGEDKKNKKPPYRFEIEMLKEKQFDK 288
>gi|16079568|ref|NP_390392.1| endonuclease IV [Bacillus subtilis subsp. subtilis str. 168] >gi|1706650|sp|P54476|END4_BACSU Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|1303840|dbj|BAA12496.1| YqfS [Bacillus subtilis] >gi|2634946|emb|CAB14443.1| yqfS [Bacillus subtilis subsp. subtilis str. 168] (297 aa)
Score = 608, Expect = 3.7e-61, Identities = 129/284 (45%), Positives = 187/284 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWKE 311
           L +GSHV    K+ L+ +  E + Y  N FM++TG PQN  RK+++   I+     M+E     ++ I+VHAPY+IN+G +   ST  LG++ L  EI RT  I +K IVLHPG+ + +     I  I + LN+ I+   N V I +ETMAGKGSE G +FEE+++I+ GV + +++ VC DTCH HD+G +I  D D  L EF K + +  IKV+H+NDSKN  G+RKDRH+NIG+G++GFD L    H+E+L ++PKILETPY     ++ KP Y+ EI  L  K++ +
  S:     2 LRIGSHVSMSGKHMLLAASQEAVSYGANTFMIYTGAPQNTRRKKIEDLNIEAGRAHMQENG---IDEIIVHAPYIINIGNTTNPSTFELGVDFLRSEIERTAAIGAKQIVLHPGAHVGAGAEAGIKKIIEGLNEVIDPNQN-VQIALETMAGKGSECGRSFEELAQIIEGVTHNEQLSVCFDTCHTHDAGYNIVEDFDGVLNEFDKIIGIDRIKVLHINDSKNVKGARKDRHENIGFGEIGFDALQYVVHHEQLKDIPKILETPYVGEDKKNKKPPYRFEIEMLKEKQFDD 288
>gi|50365149|ref|YP_053574.1| endonuclease IV [Mesoplasma florum L1] >gi|59797742|sp|Q6F1D3|END4_MESFL Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|50363705|gb|AAT75690.1| endonuclease IV [Mesoplasma florum L1] (293 aa)
Score = 606, Expect = 5.8e-61, Identities = 130/285 (45%), Positives = 189/285 (66%)
  Q:    27 KLLLGSHVGFKAKN----YLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           K +LGSHVG    N    YL+GSV E L Y+ N  M +TG PQN +R   D+  I+E  +L+KE N +  ++IVVHAPY+IN+ +P  ++T   G++ L  EI R   I  K++VLHPG+ L  D   A+N +   LN A+ ++  +VII +ETMAGKG+EVG++  +   ++  V   +++ VCLDTCHMHD+G D ++ +   EE +K +    +   HLNDSKN + + KDRH+NIGYG +GFD L+K   +E+  ++PKILETPY +DKP YK+EI NL +K + +
  S:     3 KPILGSHVGMSKSNKHGEYLIGSVKEALSYEANTLMFYTGAPQNSVRTATDKLYIEEFNQLLKENN-INKDHIVVHAPYIINISNPVNQTTWDFGVDFLKQEIKRCEDIGVKILVLHPGARLKGDYTDALNALVKGLN-AVASSQTNVIIALETMAGKGTEVGLSLNDFKYVIDNVNEPEKVAVCLDTCHMHDAGYDFNNWELIKEEINKTIGKDKVLCFHLNDSKNPLLAHKDRHENIGYGYIGFDNLLKVLWDEEYIDIPKILETPYVEDKPPYKEEIENLINKNFSK 290
>gi|116872881|ref|YP_849662.1| endonuclease IV [Listeria welshimeri serovar 6b str. SLCC5334] >gi|123463771|sp|A0AIQ1|END4_LISW6 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|116741759|emb|CAK20883.1| nfo [Listeria welshimeri serovar 6b str. SLCC5334] (297 aa)
Score = 602, Expect = 1.6e-60, Identities = 135/282 (47%), Positives = 182/282 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD-----KPIYKQEIINLNSKEW 309
           L LGSHV    K  L+G+  E   Y  N FM++TG PQN  RK +++  I+  ++ MK  +   +++IVVHAPY+IN+G S K  T  LG+N L  EI RT  + +K IVLHPG+ +    +  I  I   LN+A+   D DV I +ETMAGKGSE G  FEE+++I+ GV + + + V  DTCH HD+G DI +D D  L EF K + +  +KV+H+NDSKNE G+ KDRH NIG+G +GFD L    H+ +LANVPKILETPY  +     K  YK EI  L + E+
  S:     2 LRLGSHVSMSGKKMLLGASEEAASYGSNTFMIYTGAPQNTRRKPIEELNIEAGLEHMKAHD---MDDIVVHAPYIINIGNSVKPETFELGVNFLQSEIERTRALGAKQIVLHPGAHVGEGADKGIKQIIQGLNEAL-IHDQDVQIALETMAGKGSECGRTFEELAQIIDGVTHNELLSVTFDTCHTHDAGYDIVNDFDGVLNEFDKIIGIDRLKVLHINDSKNERGAHKDRHANIGFGHIGFDALHYVVHHPQLANVPKILETPYVGEDKASKKAPYKWEIAMLKNGEF 286
>gi|138896048|ref|YP_001126501.1| endonuclease IV [Geobacillus thermodenitrificans NG80-2] >gi|196248941|ref|ZP_03147641.1| apurinic endonuclease Apn1 [Geobacillus sp. G11MC16] >gi|166224281|sp|A4IR02|END4_GEOTN Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|134267561|gb|ABO67756.1| Endonuclease IV [Geobacillus thermodenitrificans NG80-2] >gi|196211817|gb|EDY06576.1| apurinic endonuclease Apn1 [Geobacillus sp. G11MC16] (299 aa)
Score = 601, Expect = 2.0e-60, Identities = 128/284 (45%), Positives = 180/284 (63%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKE-STRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWKE 311
           L +GSHV    K  L+ +  E + Y  N FM++TG PQN  RK +++  I+   + MK      +E+IVVHAPY+IN+G+ K   T +LG+N L  EI RT  I +K +VLHPG+ + +     +  I   LN+ +   +  V I +ETMAGKGSE G  FEE++ I+ GV    ++ VC DTCH HD+G DI +D D  L EF + + L  +KV+H+NDSKN  GSRKDRH+NIG+G +GF  L    H+ +LA++PKILETPY      + KP YK EI  L ++ + +
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGANTFMIYTGAPQNTRRKAIEELNIEAGHEHMKAHG---IEDIVVHAPYIINIGNTKNPDTFALGVNFLRAEIERTEAIGAKQLVLHPGAHVGAGAEAGLRQIIRGLNEVL-TREQTVEIALETMAGKGSECGRTFEELAYIIDGVAYNDKLSVCFDTCHTHDAGYDIVNDFDGVLSEFDRVIGLERLKVLHINDSKNPRGSRKDRHENIGFGHIGFRALNYIVHHPQLADIPKILETPYVGEDKNNKKPPYKHEIAMLRAQTFDD 288
>gi|89100490|ref|ZP_01173352.1| endonuclease IV [Bacillus sp. NRRL B-14911] >gi|89084833|gb|EAR63972.1| endonuclease IV [Bacillus sp. NRRL B-14911] (298 aa)
Score = 601, Expect = 2.1e-60, Identities = 134/284 (47%), Positives = 185/284 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-RDDK----PIYKQEIINLNSKEWKE 311
           L +GSHV    K  L+ +  E + Y  + FM++TG PQN  RK+++   I+E  + M+      ++NI+VHAPY+IN+G +   ST  LG+N L  EI+RT  I ++ IVLHPG+ + +     I  I + LN+ +   +N V I +ETMAGKGSE G NFEE++ I+ GVK    + VC DTCH HD+G +I  D D  L EF K + L  +KV+H+NDSKNE G +KDRH+NIGYG +GFD L    H+ +L+ VPKILETP+  +DK    P YK EI  L +KE+ E
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGSSTFMIYTGAPQNTRRKKIEDLNIEEGRRHMEANG---IDNIIVHAPYIINIGNTTNPSTFELGVNFLRSEIDRTEAIGARQIVLHPGAHVGAGTEEGIKKIIEGLNEVLNGEEN-VQIALETMAGKGSECGRNFEELAMIIDGVKYNDHLSVCFDTCHTHDAGYNIVEDFDGVLNEFDKIVGLDRLKVLHINDSKNERGMKKDRHENIGYGHIGFDALSYIVHHPQLSEVPKILETPFVGEDKNSKMPPYKYEIEMLRNKEFNE 288
>gi|23099393|ref|NP_692859.1| endonuclease IV [Oceanobacillus iheyensis HTE831] >gi|39931146|sp|Q8EPZ2|END4_OCEIH Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|22777622|dbj|BAC13894.1| endonuclease IV [Oceanobacillus iheyensis HTE831] (297 aa)
Score = 600, Expect = 3.0e-60, Identities = 125/272 (45%), Positives = 185/272 (68%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEI 301
           +GSHV    K  L+GS  + ++Y  N FM++TG PQN  RK +++  I+   + MK      +++IVVHAPY+IN+G S K +T  LG+N L  EI+RT  + +K IVLHPG+ +       I  I + LN+ ++   N V I +ETMAGKGSE+G  FEE+++I+ GV +  R+ +C+DTCH+HD+G +I  D D  LE+F K + +  +KV+H+NDSKNE G+ KDRH+NIG+G +GF+ L    H+ +L+++PKILETP+     ++ KP YK EI
  S:     4 IGSHVSMNGKKMLLGSSEDAVQYGANTFMIYTGAPQNTRRKPIEELNIEAGTEHMKANG---IQDIVVHAPYIINIGNSIKPATFELGVNFLKNEIDRTEALGAKQIVLHPGAHVGEGAEKGIPKIIEGLNEVLDPNSN-VQIALETMAGKGSEIGRTFEELAQIIEGVTHNDRLSICMDTCHIHDAGYNIVEDFDGVLEQFDKIIGIDRLKVVHVNDSKNERGAHKDRHENIGFGYIGFEALHNIVHHPQLSDLPKILETPFVGTDKKNKKPPYKHEI 278
>gi|194017682|ref|ZP_03056292.1| probable endonuclease 4 (Endonuclease IV)(Endodeoxyribonuclease IV) [Bacillus pumilus ATCC 7061] >gi|194010582|gb|EDW20154.1| probable endonuclease 4 (Endonuclease IV)(Endodeoxyribonuclease IV) [Bacillus pumilus ATCC 7061] (297 aa)
Score = 600, Expect = 3.1e-60, Identities = 129/284 (45%), Positives = 183/284 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWKE 311
           L +GSHV    K+ L+ +  E   Y  N FM++TG PQN  RK+++   I+     MKE     + +IVVHAPY+IN+G+    +T  LG++ L  EI RT  + ++ IVLHPG+ + +     I  I + LN+ I      V I +ETMAGKGSE G +FEE+++I+ GV + + + VC DTCH HD+G  I +D D  LEEF + + +  IKV+H+NDSKN  G+RKDRH+NIG+G++GFD L    H+ +L +VPKILETPY     ++ KP YK EI  L  K++ E
  S:     2 LKIGSHVSMSGKHMLLAASQEAASYGSNTFMIYTGAPQNTRRKKIEDLNIEAGQAHMKEHG---MTDIVVHAPYIINIGNTVNPATFELGVDFLRSEIERTEALGARQIVLHPGAHVGAGPEAGIQKIIEGLNEVI-VKGQKVQIALETMAGKGSECGRSFEELAQIIDGVTHNEALSVCFDTCHTHDAGYPIVTDFDGVLEEFDRIIGIDRIKVLHINDSKNVQGARKDRHENIGFGEIGFDALNNIVHHPQLQDVPKILETPYVGEDKKNKKPPYKFEIAMLKEKQFDE 288
>gi|46907677|ref|YP_014066.1| endonuclease IV [Listeria monocytogenes str. 4b F2365] >gi|47092739|ref|ZP_00230525.1| endonuclease IV [Listeria monocytogenes str. 4b H7858] >gi|153166860|ref|ZP_01927328.1| endonuclease IV [Listeria monocytogenes FSL N1-017] >gi|153202285|ref|ZP_01943914.1| endonuclease IV [Listeria monocytogenes HPB2262] >gi|167014702|ref|ZP_02277235.1| endonuclease IV [Listeria monocytogenes FSL J1-194] >gi|167214458|ref|ZP_02284765.1| endonuclease IV [Listeria monocytogenes FSL R2-503] >gi|167217548|ref|ZP_02287184.1| endonuclease IV [Listeria monocytogenes FSL J1-175] >gi|167454050|ref|ZP_02320273.1| endonuclease IV [Listeria monocytogenes FSL J2-064] >gi|168265937|ref|ZP_02687902.1| endonuclease IV [Listeria monocytogenes FSL J2-071] >gi|59797785|sp|Q71ZM1|END4_LISMF Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|46880945|gb|AAT04243.1| endonuclease IV [Listeria monocytogenes str. 4b F2365] >gi|47018927|gb|EAL09674.1| endonuclease IV [Listeria monocytogenes str. 4b H7858] >gi|133727266|gb|EBA28964.1| endonuclease IV [Listeria monocytogenes FSL N1-017] >gi|133735568|gb|EBA37266.1| endonuclease IV [Listeria monocytogenes HPB2262] (297 aa)
Score = 599, Expect = 3.4e-60, Identities = 134/282 (47%), Positives = 181/282 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD-----KPIYKQEIINLNSKEW 309
           L LGSHV    K  L+G+  E   Y  N FM++TG PQN  RK +++  I+  ++ MK  +   + +IVVHAPY+IN+G S K  T  LG+N L  EI RT  + +K IVLHPG+ +    +  I  I   LN+A+   D DV I +ETMAGKGSE G  FEE+++I+ GV + + + V  DTCH HD+G DI +D D  L EF K + +  +KV+H+NDSKNE G+ KDRH NIG+G +GFD L    H+ +LA+VPKILETPY  +     K  YK EI  L + E+
  S:     2 LRLGSHVSMSGKKMLLGASEEAASYGSNTFMIYTGAPQNTRRKPIEELNIEAGLEHMKAHD---MADIVVHAPYIINIGNSVKPETFELGVNFLQSEIERTRALGAKQIVLHPGAHVGEGADKGIKQIIQGLNEAL-IHDQDVQIALETMAGKGSECGRTFEEIAQIIDGVTHNELLSVTFDTCHTHDAGYDIVNDFDGVLNEFDKIIGVDRLKVLHINDSKNERGAHKDRHANIGFGHIGFDALHYIVHHPQLADVPKILETPYVGEDKASKKAPYKWEIAMLRNGEF 286
>gi|169190205|ref|ZP_02850179.1| apurinic endonuclease Apn1 [Paenibacillus sp. JDR-2] >gi|169003100|gb|EDS49973.1| apurinic endonuclease Apn1 [Paenibacillus sp. JDR-2] (376 aa)
Score = 599, Expect = 3.4e-60, Identities = 127/274 (46%), Positives = 182/274 (66%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEAT-DNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID-ISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY--RDDK---PIYKQEI 301
           L +GSHV F  K  L  +  E + Y  + FM++TG PQN  RK ++   I+E  ++M++     +  IVVHAPY+INLGS KE T  L +  L  EI RT+ I  + IVLHPG+  D D    I  IA+ LN+ +E T D +V I +ETMAGKG+E+G +FEE+++I+  V+N  R+ VC+DTCHMHD+G D I+D D  L++F + + L  + V+H+NDSKN +G+ KDRH  +G G +G + + +  H+E LA  P ILETP+  +DDK   P+Y+ EI
  S:     2 LKIGSHVSFSDKGLLTAAK-EAVSYGSSSFMIYTGAPQNTRRKPIETLYIEEGKQMMEQAG---INEIVVHAPYIINLGSYKEDTFELAVRFLQEEIRRTDYIGVRNIVLHPGAYTDKDAEYGIARIAEGLNEVLEGTKDTNVNIALETMAGKGTEIGRSFEELAQIIDKVQNNDRLTVCMDTCHMHDAGYDLINDLDGVLQKFDQTVGLDRVAVVHVNDSKNPVGAGKDRHAPVGAGWLGHEAIHRIVHHEALAGRPFILETPWIGKDDKKQFPMYEAEI 278
>gi|73662508|ref|YP_301289.1| endonuclease IV [Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305] >gi|123642692|sp|Q49Y00|END4_STAS1 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|72495023|dbj|BAE18344.1| endonuclease IV [Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305] (296 aa)
Score = 599, Expect = 3.7e-60, Identities = 131/284 (46%), Positives = 185/284 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWKE 311
           +LLGSHV    K  L GS  E  ++  + FM++TG PQN  RK +++  I++  ++MK      L NIVVHAPY+IN+ +  K     LG+  L  EI RT  + ++ IVLHPGS +    +  I  I + LN+ +   DN+V I +ETMAGKGSEVG NFEE+++I+ GV +  R+ VC DTCH HD+G ++  D D  L EF K + +  IKV+H+NDSKN+IG+ KDRH+NIG+G +GFD L    H++   ++PKILETPY     ++ KP YK EI  L  +++ E
  S:     1 MLLGSHVSMNGKKMLEGSAEEAHKFGESTFMIYTGAPQNTRRKPIEELNIEKGHEIMKAHG---LSNIVVHAPYIINIANTVKPHVFELGVEFLQSEIERTQALGAQDIVLHPGSHVGEGTDAGIKKIIEGLNEVL-TNDNNVRIALETMAGKGSEVGRNFEELARIIDGVNHNDRLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSKNDIGAHKDRHENIGFGYIGFDALNYVVHHDTFKDIPKILETPYVGEDKKNKKPPYKLEIEMLKQQKFDE 287
>gi|157693013|ref|YP_001487475.1| endonuclease IV [Bacillus pumilus SAFR-032] >gi|157681771|gb|ABV62915.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus pumilus SAFR-032] (296 aa)
Score = 598, Expect = 4.8e-60, Identities = 128/282 (45%), Positives = 182/282 (64%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWKE 311
           +GSHV    K+ L+ +  E   Y  N FM++TG PQN  RK+++   I+     MKE     + +IVVHAPY+IN+G+    +T  LG++ L  EI RT  + ++ IVLHPG+ + +     I  I + LN+ I      V I +ETMAGKGSE G +FEE+++I+ GV + + + VC DTCH HD+G  I +D D  LEEF + + +  IKV+H+NDSKN  G+RKDRH+NIG+G++GFD L    H+ +L +VPKILETPY     ++ KP YK EI  L  K++ E
  S:     3 IGSHVSMSGKHMLLAASQEAASYGSNTFMIYTGAPQNTRRKKIEDLNIEAGQAHMKEHG---MTDIVVHAPYIINIGNTVNPATFELGVDFLRSEIERTEALGARQIVLHPGAHVGAGPEAGIQKIIEGLNEVI-VKGQKVQIALETMAGKGSECGRSFEELAQIIDGVTHNEALSVCFDTCHTHDAGYPIVTDFDGVLEEFDRIIGIDRIKVLHINDSKNVQGARKDRHENIGFGEIGFDALNNIVHHPQLQDVPKILETPYVGEDKKNKKPPYKFEIAMLKEKQFDE 287
>gi|52081050|ref|YP_079841.1| endonuclease IV [Bacillus licheniformis ATCC 14580] >gi|52786428|ref|YP_092257.1| endonuclease IV [Bacillus licheniformis ATCC 14580] >gi|81385051|sp|Q65HA0|END4_BACLD Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|52004261|gb|AAU24203.1| type IV apurinic/apyrimidinic endonuclease [Bacillus licheniformis ATCC 14580] >gi|52348930|gb|AAU41564.1| YqfS [Bacillus licheniformis DSM 13] (297 aa)
Score = 597, Expect = 5.9e-60, Identities = 127/284 (44%), Positives = 185/284 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWKE 311
           L +GSHV    K+ L+ +  E   Y  N FM++TG PQN  RK+++   I+     M+E     + +IVVHAPY+IN+  +   +T  LG+  L  EI RT+ I ++ IVLHPG+ + +     I  I + LN+ I+   N V I +ETMAGKGSE G  FEE+++I+ GV + + + VC DTCH HD+G D+ SD D  L EF K + +  +KV+H+NDSKN  G+RKDRH+NIG+G++GFD L    H+++L ++PKILETPY     ++ KP Y+ EI  L +K++ E
  S:     2 LKIGSHVSMSGKHMLLAASQEASSYGANTFMIYTGAPQNTRRKKIEDLNIEAGRAHMEENG---ISDIVVHAPYIINIANTTNPATFELGVEFLRSEIERTSAIGARQIVLHPGAHVGAGAETGIQKIIEGLNEVIDPNQN-VQIALETMAGKGSECGRTFEELAQIIDGVTHNEHLSVCFDTCHTHDAGYDVVSDFDGVLNEFDKIVGIDRLKVLHINDSKNVRGARKDRHENIGFGEIGFDALQYIVHHDQLKDIPKILETPYVGEDKKNKKPPYRFEIEMLKNKQFDE 288
>gi|15613949|ref|NP_242252.1| endonuclease IV [Bacillus halodurans C-125] >gi|20138004|sp|Q9KD33|END4_BACHD Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|10174002|dbj|BAB05105.1| endonuclease IV [Bacillus halodurans C-125] (298 aa)
Score = 597, Expect = 6.6e-60, Identities = 131/274 (47%), Positives = 181/274 (66%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND-VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEI 301
           L LGSHV    K  L+GS  E + Y  N FMV+TG PQN  RK +++  I+     MKE     +++I+VHAPY+IN+G S K +T  LG++ L  EI RT  + +  IVLHPG+ + +  +  I  I + LN+ +  T+ND V I +ETMAGKGSE G  FEE+++I++GV +  R+ VC DTCH HD+G +I  D D  L EF K + +  IKV+H+NDSKN  G+ KDRH+NIG+G +GF  L    H+ +L ++PKILETPY     ++ KP YK EI
  S:     3 LHLGSHVSMNGKKMLLGSSEEAISYGANTFMVYTGAPQNTRRKPIEELNIEAGRAHMKENG---IDHIIVHAPYIINIGNSEKPATFKLGVDFLQSEIERTQALGADQIVLHPGAHVGAGVDKGIEKIIEGLNEVL--TENDGVQIALETMAGKGSECGRTFEEIARIINGVTHNDRLSVCFDTCHTHDAGYNIVEDFDGVLNEFDKIIGVERIKVLHINDSKNPRGAAKDRHENIGFGHIGFKALHYIVHHPQLQDIPKILETPYVGEDKKNKKPPYKFEI 279
>gi|16800555|ref|NP_470823.1| endonuclease IV [Listeria innocua Clip11262] >gi|24636838|sp|Q92BR0|END4_LISIN Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|16413960|emb|CAC96718.1| lin1487 [Listeria innocua] (297 aa)
Score = 597, Expect = 6.7e-60, Identities = 133/282 (47%), Positives = 181/282 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD-----KPIYKQEIINLNSKEW 309
           L LGSHV    K  L+G+  E   Y  N FM++TG PQN  RK +++  I+  ++ MK  +   + +IVVHAPY+IN+G S K  T  LG+N L  EI RT  + +K IVLHPG+ +    +  I  I   LN+A+   D DV I +ETMAGKGSE G  FEE+++I+ GV + + + V  DTCH HD+G DI +D D  L EF K + +  +KV+H+NDSKNE G+ KDRH NIG+G +GFD L    H+ +L+N+PKILETPY  +     K  YK EI  L + E+
  S:     2 LRLGSHVSMSGKKMLLGASEEAASYGSNTFMIYTGAPQNTRRKPIEELNIEAGLEHMKAHD---MADIVVHAPYIINIGNSVKPETFELGVNFLQSEIERTRALGAKQIVLHPGAHVGEGADKGIKQIIQGLNEAL-IHDQDVQIALETMAGKGSECGRTFEELAQIIDGVTHNELLSVTFDTCHTHDAGYDIVNDFDGVLNEFDKIIGIDRLKVLHINDSKNERGAHKDRHANIGFGHIGFDALHYIVHHPQLSNIPKILETPYVGEDKASKKAPYKWEIAMLRNGEF 286
>gi|167767674|ref|ZP_02439727.1| hypothetical protein CLOSS21_02209 [Clostridium sp. SS2/1] >gi|167710691|gb|EDS21270.1| hypothetical protein CLOSS21_02209 [Clostridium sp. SS2/1] (316 aa)
Score = 596, Expect = 8.7e-60, Identities = 132/293 (45%), Positives = 187/293 (63%)
  Q:    17 KTKEMCMSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP--DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY---RDDK---PIYKQEIINLNSKEW 309
           K ++  +    +L+GSHVG K K+  +GSV E L Y  N FMV+TG PQN  RK++++  I++  KLMKE     +E  VVHAPY+INL  + K  T  L +  L VE+ RT  + S  +VLHPGS + +  +  I+ I + LN+ +   D  V I +ETMAGKGSE+G  FEE+ +I  GVK  +++ VC DTCH+ DSG+D+S    +  +++F K +    I V H+NDSKN IG+ KDRH+N+G+G +GF+ L    H++    VPKILETPY    D K   P YK EI  L  +++
  S:     5 KEEKFLIGGKIMLIGSHVGMKGKDMFLGSVKEALSYGANTFMVYTGAPQNTRRKKIEELRIEDGTKLMKEHG---METFVVHAPYIINLANTTKPETFELAVEFLEVEVERTKAMGSHTLVLHPGSHVGAGVDKGIDRIIEGLNQVM-YQDMPVHIALETMAGKGSEIGREFEELKRIYDGVKYPEKLRVCFDTCHVSDSGLDLSGEGFENVIDQFDKTIGKDQIAVFHINDSKNVIGAGKDRHENLGFGTIGFETLNHIVHHKDFEQVPKILETPYIKAEDSKKSYPPYKYEIEMLKQEQF 302
>gi|56963463|ref|YP_175194.1| endonuclease IV [Bacillus clausii KSM-K16] >gi|59797660|sp|Q5WHC2|END4_BACSK Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|56909706|dbj|BAD64233.1| endonuclease IV [Bacillus clausii KSM-K16] (292 aa)
Score = 596, Expect = 9.3e-60, Identities = 128/274 (46%), Positives = 173/274 (63%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEI 301
           LL+GSHV    K  L+ S  E   Y    FM++TG PQN  RK ++   I+     M E     L NIVVHAPY+IN+G + K  T  LG++ L  EI RT  I +K IVLHPG+ + +     I  I + LN+ +     DV I +ETMAGKGSE G  FEE++KI+ GV + +R+ VC DTCH HD+G DI +D D  L+EF + +    IKV+H+NDSKNE  +RKDRH+NIG+G +G   L    H+++  ++PKILETP+     +D +P YK EI
  S:     3 LLIGSHVSMSGKKMLLQSSEEAASYGATTFMIYTGAPQNTRRKAIEDLNIEAGKAHMAEHG---LSNIVVHAPYIINIGNTQKPETFRLGVDFLRSEIERTEAIGAKQIVLHPGAHVGAGAEEGIKKIIEGLNEVL-TEKRDVQIALETMAGKGSECGCTFEELAKIIDGVTHNERLSVCFDTCHTHDAGYDIVNDFDGVLDEFDRIIGAERIKVVHINDSKNERSARKDRHENIGHGHIGLKALDYIVHHDQFKDIPKILETPFIGKDKKDKRPPYKHEI 279
>gi|169829132|ref|YP_001699290.1| endonuclease 4 [Lysinibacillus sphaericus C3-41] >gi|168993620|gb|ACA41160.1| Probable endonuclease 4 [Lysinibacillus sphaericus C3-41] (297 aa)
Score = 595, Expect = 1.2e-59, Identities = 132/283 (46%), Positives = 182/283 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKEL-DQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-------RDDKPIYKQEIINLNSKEWK 310
           +LLGSHV    K  L+GS  E L Y  N FM++TG PQN  RK + D N+++  +  MKE     + NIVVHAPY+IN+G + K  T  LG++ L  EI RT  + +  IVLHPG+ + +  +  I  I + LN+ + + D  V I +ETMAGKG+E G +FEE++KI+ GV + +R+ VC DTCH HD+G +I  D D  L EF K + +  IKV+H+NDSKN  G+ KDRH+NIG+G +GFD L    H+ +L  +PKILETP+       +     YK EI  L S  +K
  S:     1 MLLGSHVSMSGKEMLLGSSKEALSYGANTFMIYTGAPQNTRRKAIADLNIMNGRLH-MKEHG---MTNIVVHAPYIINIGNTEKPETFRLGVDFLQSEIERTAALEATQIVLHPGAHVGAGADAGIAKIIEGLNEVL-SQDYPVQIALETMAGKGTECGRSFEELAKIIDGVTHNERLSVCFDTCHTHDAGYNIVEDFDGVLNEFDKLIGVDRIKVLHINDSKNVRGAAKDRHENIGFGHIGFDALNYVVHHPQLMAIPKILETPFVPLASDAKSKSAPYKAEIEMLRSSTFK 288
>gi|16803489|ref|NP_464974.1| endonuclease IV [Listeria monocytogenes EGD-e] >gi|24636826|sp|Q8Y756|END4_LISMO Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|16410878|emb|CAC99527.1| lmo1449 [Listeria monocytogenes] (297 aa)
Score = 594, Expect = 1.3e-59, Identities = 133/282 (47%), Positives = 180/282 (63%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEW 309
           L LGSHV    K  L+G+  E   Y  N FM++TG PQN  RK +++  I+  ++ MK  +   + +IVVHAPY+IN+G S K  T  LG+N L  EI RT  + +K IVLHPG+ +    +  I  I   LN+A+   D DV I +ETMAGKGSE G  FEE+++I+ GV + + + V  DTCH HD+G DI +D D  L +F K + +  +KV+H+NDSKNE G+ KDRH NIG+G +GFD L    H+ +LA+VPKILETPY        K  YK EI  L + E+
  S:     2 LRLGSHVSMSGKKMLLGASEEAASYGSNTFMIYTGAPQNTRRKPIEELNIEAGLEHMKAHD---MADIVVHAPYIINIGNSVKPETFELGVNFLQSEIERTRALGAKQIVLHPGAHVGEGADKGIKQIIQGLNEAL-IHDQDVQIALETMAGKGSECGRTFEELAQIIDGVTHNELLSVTFDTCHTHDAGYDIVNDFDGVLNQFDKIVGIDRLKVLHINDSKNERGAHKDRHANIGFGHIGFDALHYIVHHPQLADVPKILETPYVGGDKASKKAPYKWEIAMLKNGEF 286
>gi|47095400|ref|ZP_00233010.1| endonuclease IV [Listeria monocytogenes str. 1/2a F6854] >gi|153174576|ref|ZP_01930077.1| endonuclease IV [Listeria monocytogenes FSL N3-165] >gi|153179504|ref|ZP_01932723.1| endonuclease IV [Listeria monocytogenes F6900] >gi|153190840|ref|ZP_01938203.1| endonuclease IV [Listeria monocytogenes J2818] >gi|47016221|gb|EAL07144.1| endonuclease IV [Listeria monocytogenes str. 1/2a F6854] >gi|127765824|gb|EBA26169.1| endonuclease IV [Listeria monocytogenes J2818] >gi|133730180|gb|EBA31878.1| endonuclease IV [Listeria monocytogenes FSL N3-165] >gi|133732989|gb|EBA34687.1| endonuclease IV [Listeria monocytogenes F6900] (297 aa)
Score = 594, Expect = 1.4e-59, Identities = 133/282 (47%), Positives = 181/282 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD-----KPIYKQEIINLNSKEW 309
           L LGSHV    K  L+G+  E   Y  N FM++TG PQN  RK +++  I+  ++ MK  +   + +IVVHAPY+IN+G S K  T  LG+N L  EI RT  + +K IVLHPG+ +    +  I  I   LN+A+   D DV I +ETMAGKGSE G  FEE+++I+ GV + + + V  DTCH HD+G DI +D D  L +F K + +  +KV+H+NDSKNE G+ KDRH NIG+G +GFD L    H+ +LA+VPKILETPY  +     K  YK EI  L + E+
  S:     2 LRLGSHVSMSGKKMLLGASEEAASYGSNTFMIYTGAPQNTRRKPIEELNIEAGLEHMKAHD---MADIVVHAPYIINIGNSVKPETFELGVNFLQSEIERTRALGAKQIVLHPGAHVGEGADKGIKQIIQGLNEAL-IHDQDVQIALETMAGKGSECGRTFEELAQIIDGVTHNELLSVTFDTCHTHDAGYDIVNDFDGVLNQFDKIVGIDRLKVLHINDSKNERGAHKDRHANIGFGHIGFDALHYIVHHPQLADVPKILETPYVGEDKASKKAPYKWEIAMLKNGEF 286
>gi|153196227|ref|ZP_01940635.1| endonuclease IV [Listeria monocytogenes 10403S] >gi|127634509|gb|EBA23895.1| endonuclease IV [Listeria monocytogenes 10403S] (297 aa)
Score = 594, Expect = 1.5e-59, Identities = 133/282 (47%), Positives = 181/282 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD-----KPIYKQEIINLNSKEW 309
           L LGSHV    K  L+G+  E   Y  N FM++TG PQN  RK +++  I+  ++ MK  +   + +IVVHAPY+IN+G S K  T  LG+N L  EI RT  + +K IVLHPG+ +    +  I  I   LN+A+   D DV I +ETMAGKGSE G  FEE+++I+ GV + + + V  DTCH HD+G DI +D D  L +F K + +  +KV+H+NDSKNE G+ KDRH NIG+G +GFD L    H+ +LA+VPKILETPY  +     K  YK EI  L + E+
  S:     2 LRLGSHVSMSGKKMLLGASEEAASYGSNTFMIYTGAPQNTRRKPIEELNIEAGLEHMKAHD---MADIVVHAPYIINIGNSVKPETFKLGVNFLQSEIERTRALGAKQIVLHPGAHVGEGADKGIKQIIQGLNEAL-IHDQDVQIALETMAGKGSECGRTFEELAQIIDGVTHNELLSVTFDTCHTHDAGYDIVNDFDGVLNQFDKIVGIDRLKVLHINDSKNERGAHKDRHANIGFGHIGFDALHYIVHHPQLADVPKILETPYVGEDKASKKAPYKWEIAMLKNGEF 286
>gi|27468162|ref|NP_764799.1| endonuclease IV [Staphylococcus epidermidis ATCC 12228] >gi|57867090|ref|YP_188699.1| endonuclease IV [Staphylococcus epidermidis RP62A] >gi|38257570|sp|Q8CP25|END4_STAES Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|71151864|sp|Q5HNZ1|END4_STAEQ Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|27315708|gb|AAO04843.1|AE016748_77 endonuclease IV [Staphylococcus epidermidis ATCC 12228] >gi|57637748|gb|AAW54536.1| endonuclease IV [Staphylococcus epidermidis RP62A] (296 aa)
Score = 592, Expect = 2.6e-59, Identities = 129/282 (45%), Positives = 185/282 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEW 309
           +L+GSHV    K  L GS  E  +Y  + FM++TG PQN  RK ++   I++  + MK      L NIVVHAPY+IN+  + K    +LG++ L  EI RT  + +K IVLHPG+ + +  +  I  I + LN+ +   DNDV I +ETMAGKG+EVG +FEE+++I+ GV +  R+ VC DTCH HD+G ++  D D  LE+F   + +  IKV+H+NDSKN  G++KDRH+NIG+G +GFD L    H++   N+PKILETPY     ++ KP YK EI  L S+++
  S:     1 MLIGSHVSMSGKKMLQGSAEEAHKYGESTFMIYTGAPQNTRRKNIEDLNIEKGQQAMKTYG---LSNIVVHAPYIINIANTTKPEVFNLGVDFLQKEIERTQALGAKDIVLHPGAHVGAGVDKGIQKIIEGLNEVL-THDNDVRIALETMAGKGTEVGRSFEEIAQIIDGVTHNDRLSVCFDTCHTHDAGYNVKEDFDGVLEKFDSIIGVDRIKVVHVNDSKNLRGAQKDRHENIGFGHIGFDALNYVVHHDTFKNIPKILETPYVGEDKKNKKPPYKLEIDMLKSQKF 285
>gi|70726360|ref|YP_253274.1| endonuclease IV [Staphylococcus haemolyticus JCSC1435] >gi|123660322|sp|Q4L6Q7|END4_STAHJ Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|68447084|dbj|BAE04668.1| unnamed protein product [Staphylococcus haemolyticus JCSC1435] (296 aa)
Score = 591, Expect = 3.1e-59, Identities = 130/282 (46%), Positives = 182/282 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEW 309
           +LLGSHV    K  L GS  E  ++  + FM++TG PQN  RK ++   I++  + M +     L N+VVHAPY+IN+  + K     LG++ L  EI RT  + +K IVLHPGS + +  +  I  I   LN+ +   DNDV I +ETMAGKGSEVG  FEE+++I+ GV +  R+ +C DTCH HD+G +I  D D  L EF K + L  IKV+H+NDSKNE G+ KDRH+NIG+G +GFD L    H++   ++PKILETPY     ++ KP YK EI  L ++++
  S:     1 MLLGSHVSMSGKKMLEGSAEEAHKFGESTFMIYTGAPQNTRRKSIEDLNIEKGHEAMDKYG---LSNLVVHAPYIINIANTTKPEVFQLGVDFLQNEIERTQALGAKDIVLHPGSHVGAGADKGIQQIIKGLNEVL-THDNDVRIALETMAGKGSEVGRTFEEIAQIIDGVTHNDRLSICFDTCHTHDAGYNIKEDFDGVLNEFDKIIGLDRIKVVHVNDSKNEQGAHKDRHENIGFGHIGFDALNYVVHHDVFKDIPKILETPYVGEDKKNKKPPYKFEIEMLKAQQF 285
>gi|160879451|ref|YP_001558419.1| endonuclease IV [Clostridium phytofermentans ISDg] >gi|189037123|sp|A9KNS9|END4_CLOPH Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|160428117|gb|ABX41680.1| apurinic endonuclease Apn1 [Clostridium phytofermentans ISDg] (300 aa)
Score = 591, Expect = 3.3e-59, Identities = 125/274 (45%), Positives = 170/274 (62%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-------RDDKPIYKQEI 301
           L +GSHVG   K    GS  E   YD N FMV+TG PQN  RK++    ++E  + MK+     + +IV+HAPY+INLG S    T SL ++ L  E+ RT    SK +VLHPG+ + +  +  I  I   LN+ +   D D+ I +ETMAGKGSE+G NFEE+++I  GVK   R+ VC DTCH +D+G D+ +D D  +E+F K +    I V H+NDSKN+ G+ KDRH+NIG+G +GFD +    H+     VPKILETPY           P Y+ EI
  S:     2 LKIGSHVGMSGKEAFFGSAKEAHSYDANTFMVYTGAPQNTRRKDISDLRLEEGFEFMKQHG---ISDIVIHAPYIINLGNSVNLDTYSLAVDFLAKEMERTKAFRSKYLVLHPGAHVGAGVDAGIKQIVQGLNEVL-TRDTDLYIALETMAGKGSEIGRNFEELARIYDGVKYNDRLRVCFDTCHTNDAGYDVVNDFDGVIEQFDKLIGKEQIAVFHINDSKNDRGASKDRHENIGFGTLGFDAISYIVHHSDFIEVPKILETPYVSLPNEKEKSLPPYRYEI 280
>gi|126652236|ref|ZP_01724415.1| endonuclease IV [Bacillus sp. B14905] >gi|126590968|gb|EAZ85080.1| endonuclease IV [Bacillus sp. B14905] (297 aa)
Score = 590, Expect = 3.7e-59, Identities = 130/283 (45%), Positives = 178/283 (62%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-------RDDKPIYKQEIINLNSKEWK 310
           +LLGSHV    K  L+GS  E L Y  N FM++TG PQN  RK +    I   +  MKE     + NIVVHAPY+IN+G + K  T  LG++ L  EI RT  + +  IVLHPG+ + +  +  I  I + LN+ + + +  V I +ETMAGKG+E G +FEE++KI+ GV + +R+ VC DTCH HD+G +I  D D  L EF K + +  IKV+H+NDSKN  G+ KDRH+NIG+G +GFD L    H+ +L  +PKILETP+       +     YK EI  L S  +K
  S:     1 MLLGSHVSMSGKEMLLGSSKEALSYGANTFMIYTGAPQNTRRKAIADLNIMNGLLHMKEHG---MTNIVVHAPYIINIGNTEKPETFRLGVDFLQSEIERTAALEATQIVLHPGAHVGAGADAGIAKIIEGLNEVL-SQEYPVQIALETMAGKGTECGRSFEELAKIIDGVTHNERLSVCFDTCHTHDAGYNIVEDFDGVLNEFDKLIGVDRIKVLHINDSKNVRGAAKDRHENIGFGHIGFDALNYVVHHPQLMAIPKILETPFVPLASDAKSKSAPYKAEIDMLRSSTFK 288
>gi|56421009|ref|YP_148327.1| endonuclease IV [Geobacillus kaustophilus HTA426] >gi|81346830|sp|Q5KX27|END4_GEOKA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|56380851|dbj|BAD76759.1| endonuclease IV [Geobacillus kaustophilus HTA426] (299 aa)
Score = 590, Expect = 3.9e-59, Identities = 127/284 (44%), Positives = 177/284 (62%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKE-STRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWKE 311
           L +GSHV    K  L+ +  E   Y  N FM++TG PQN  RK +++  I+   + M+      +E IVVHAPY+IN+G+     T SLG++ L  EI RT  I +K +VLHPG+ + +     +  I   LN+ +    N V I +ETMAGKGSE G  FEE++ I+ GV    ++ VC DTCH HD+G DI +D D  LEEF + + L  +KV+H+NDSKN  GSRKDRH+NIG+G +GF  L    H+ +L ++PKILETPY      + KP YK EI  L ++ + +
  S:     2 LKIGSHVSMSGKKMLLAASEEAASYGANTFMIYTGAPQNTKRKSIEELNIEAGRQHMQAHG---IEEIVVHAPYIINIGNTTNLDTFSLGVDFLRAEIERTEAIGAKQLVLHPGAHVGAGVEAGLRQIIRGLNEVLTREQN-VQIALETMAGKGSECGRTFEELAYIIDGVAYNDKLSVCFDTCHTHDAGYDIVNDFDGVLEEFDRIIGLGRLKVLHINDSKNPRGSRKDRHENIGFGHIGFAALNYIVHHPQLEDIPKILETPYVGEDKNNKKPPYKHEIAMLRAQSFDD 288
>gi|167404432|ref|ZP_02309228.1| endonuclease IV [Listeria monocytogenes FSL J2-003] (297 aa)
Score = 589, Expect = 5.2e-59, Identities = 132/282 (46%), Positives = 180/282 (63%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD-----KPIYKQEIINLNSKEW 309
           L LGSHV    K  L+G+  E   Y  N FM++TG PQN  RK +++  I+  ++ MK  +   + +IVVHAPY+IN+G S K  T  LG+N L  EI RT  + +K IVLHPG+ +    +  I  I   LN+A+   D DV I +ETMAGKGSE G  FEE+++I+ GV + + + V  DTCH HD+G DI +D D  L +F K + +  +KV+H+NDSKNE G+ KDRH NIG+G +GFD L    H+ +L +VPKILETPY  +     K  YK EI  L + E+
  S:     2 LRLGSHVSMSGKKMLLGASEEAASYGSNTFMIYTGAPQNTRRKPIEELNIEAGLEHMKAHD---MADIVVHAPYIINIGNSVKPETFKLGVNFLQSEIERTRALGAKQIVLHPGAHVGEGADKGIKQIIQGLNEAL-IHDQDVQIALETMAGKGSECGRTFEELAQIIDGVTHNELLSVTFDTCHTHDAGYDIVNDFDGVLNQFDKIVGIDRLKVLHINDSKNERGAHKDRHANIGFGHIGFDALHYIVHHPQLVDVPKILETPYVGEDKASKKAPYKWEIAMLKNGEF 286
>gi|172056877|ref|YP_001813337.1| apurinic endonuclease Apn1 [Exiguobacterium sibiricum 255-15] >gi|171989398|gb|ACB60320.1| apurinic endonuclease Apn1 [Exiguobacterium sibiricum 255-15] (299 aa)
Score = 589, Expect = 5.6e-59, Identities = 131/281 (46%), Positives = 180/281 (64%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID-ISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNS----KEWK 310
           +GSHV    K  L+G+  E   Y     MV+TG PQN  RK +    I EA+  M+E     +E IVVHAPY+INLG + K  T  L ++ L  EI R   +  +K IVLHPG+ + +   V I  I + LN+ +   D  V I +ETMAGKGSE+G  FEE++ I++GV +  R+ VCLDTCH+HD+G D I D D  LE F + + ++ + VIH+NDSKN  G++KDRH+NIG+G++GFD L +  H+  LA++PKILETPY     R     Y++EI  L S     EW+
  S:     3 IGSHVSLSGKKMLLGASEEAASYGATTMMVYTGAPQNTRRKPISDLRIPEALLHMEENG---IEEIVVHAPYIINLGNTTKPETFELAVSFLGEEIRRAEALEKAKHIVLHPGAHVGAGEEVGIKRIIEGLNEVLTG-DEKVKIALETMAGKGSEIGKTFEEIAAIIAGVTHNDRLSVCLDTCHVHDAGYDLIHDLDGVLESFDRIVGINRLGVIHVNDSKNIRGAKKDRHENIGFGEIGFDPLHRIVHHRDLAHLPKILETPYIGLDPRKKVAPYREEIAMLRSGNFDAEWR 291
>gi|163762611|ref|ZP_02169675.1| Deoxyribonuclease IV (phage-T(4)-induced) [Bacillus selenitireducens MLS10] >gi|160356544|gb|EDP83193.1| Deoxyribonuclease IV (phage-T(4)-induced) [Bacillus selenitireducens MLS10] (300 aa)
Score = 586, Expect = 1.2e-58, Identities = 126/284 (44%), Positives = 185/284 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-RDDK----PIYKQEIINLNSKEWKE 311
           + LGSHV    K  L+ +  E   Y    FM++TG PQN  RK ++   I+     M +     +++IVVHAPY+IN+  + K  T  LG++ L  EI+RT  + +K IVLHPG+ + +  +  I  I + LN+ I+  D DV I +ETMAGKGSE G +FEE++KI+ GV + +++ VC DTCH+HD+G DI +D D  L+EF   + L  +KV+H+NDSKNE G+ KDRH+NIG+G +GF+ + +  H+E   ++PKILETPY  +DK    P YK+EI  L  + + +
  S:     1 MWLGSHVSMSGKKMLLAASEEAAGYGSTTFMIYTGAPQNTRRKAIEDLNIEAGRAHMNQHG---IDHIVVHAPYIINIANTTKPETFQLGVDFLKSEIDRTEALGAKQIVLHPGAHVGAGADQGIAKIIEGLNEVIDP-DIDVQIALETMAGKGSECGRSFEELAKIIDGVTHNEKLSVCFDTCHVHDAGYDIVNDLDGVLKEFDDIVGLDRLKVLHINDSKNERGASKDRHENIGFGYIGFEAIDRILHHEAFGDIPKILETPYVGEDKKKRVPPYKEEIAMLRKRTFDD 287
>gi|187605937|ref|ZP_02992118.1| apurinic endonuclease Apn1 [Exiguobacterium sp. AT1b] >gi|187481993|gb|EDU20016.1| apurinic endonuclease Apn1 [Exiguobacterium sp. AT1b] (300 aa)
Score = 582, Expect = 3.4e-58, Identities = 126/284 (44%), Positives = 180/284 (63%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID-ISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEI----INLNSKEWKE 311
           L +GSHV    K  L+    E + Y  N  MV+TG PQN  RK ++   I+ A+K M   +   +E IVVHAPY+INLG + K  T  L ++ L  E+ R   +  ++ +VLHPG+ + +   + +  I + LN+ +   D  V I +ETMAGKGSE+G  FEE++ I+ GV +  R+ VC DTCH+HD+G D + D D  +E+F + + L  + VIH+NDSKN  G++KDRH+NIGYG++GFD L +  H+E  A++PKILETPY     +     YKQEI     N    EW+E
  S:     2 LKIGSHVSVSGKKMLLAGSEEAVSYGANTMMVYTGAPQNTRRKPIEDLNIEAALKHMAAHD---IEEIVVHAPYIINLGNTTKPETFELAVSFLTQELKRAEALQVARHVVLHPGAHVGAGEEIGLARIIEGLNEVLTG-DEKVKIALETMAGKGSELGKTFEELATIIDGVTHNDRLSVCFDTCHVHDAGYDLVGDLDGVIEQFDRIVGLDRLGVIHVNDSKNVRGAKKDRHENIGYGEIGFDTLNRVIHHEAFAHLPKILETPYIPISEKTKVAPYKQEIEMFRTNQFDAEWRE 293
>gi|28378618|ref|NP_785510.1| endonuclease IV [Lactobacillus plantarum WCFS1] >gi|38257510|sp|Q88VR2|END4_LACPL Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|28271454|emb|CAD64359.1| deoxyribonuclease IV [Lactobacillus plantarum WCFS1] (298 aa)
Score = 580, Expect = 6.1e-58, Identities = 130/282 (46%), Positives = 175/282 (62%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTR-SLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP-DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-RDDK----PIYKQEIINLNSKEW 309
           L LGSHV  KA + L+GS  E   Y  N FM++TG PQN  RK +D+  IDEA  +++  +   L  IVVHAPY+INLG+ K+        + L  EI R + + +  + LHPG+ + +  NVAI  I   LN  I   +  V I +ETMAGKG+EVG  FEE+++++ GV   +++ V  DTCH  D+G  I D  D  L EF   + L  +KVIHLNDSKN  G+ KDRH NIG G +GFD L K AH+ +L ++ KILETPY  +DK    P YK EI  L + ++
  S:     2 LRLGSHVSMKAPDMLLGSANEAASYGANTFMIYTGAPQNTRRKPIDELKIDEAQPIIEAHD---LRQIVVHAPYIINLGNTKKPGYFEFATDFLYQEIQRADAVGATQLTLHPGAHIGAGANVAITQIIKGLNAVIRP-EQHVQIALETMAGKGTEVGRTFEELAQMIDGVTYNEKLSVTFDTCHTSDAGYAIKDDFDGVLNEFDHVIGLDRLKVIHLNDSKNPQGAHKDRHTNIGMGTIGFDTLNKVAHHPQLPDISKILETPYVGEDKKHQLPPYKYEIAMLRAGQF 286
>gi|71894149|ref|YP_278257.1| endonuclease IV [Mycoplasma synoviae 53] >gi|123644452|sp|Q4A6S5|END4_MYCS5 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|71850937|gb|AAZ43546.1| endonuclease IV [Mycoplasma synoviae 53] (277 aa)
Score = 573, Expect = 3.6e-57, Identities = 122/279 (43%), Positives = 175/279 (62%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           LGSHV FK  NYL G+  E++    N  M++ G PQ   R E +     E +    +  P   E+I+VHAPY+IN  +P ++  S     LI EINR N I++K +VLHPG+  +     A++ +  +L   +  T  DV+IC+ETMAGKG+E+GINFE++S +++ + N  RI +CLDTCH+ D+G ++ D     +E  K+  L ++KVIHLNDSKNE+ S KDRH NI  G +G + L K+ H++   N+P ILETPY D+KPIY  EI  L +K+
  S:     4 LGSHVSFKKPNYLAGAAGESINNKANTMMIYLGAPQTTKRVEFELYKKQEYLDFYAKDIPA--EDIIVHAPYIINPANPTKAKFSCDF--LIQEINRMNYINAKYLVLHPGAYTEFAPQEALDQLVKSLTHILSKT-KDVVICIETMAGKGTEIGINFEQISYLINKL-NSDRIAICLDTCHLWDAGYNLKDYQSFKDELKKWNLLKHVKVIHLNDSKNELSSHKDRHANIDQGHIGLETLAKFVHDKDFDNIPIILETPYVDNKPIYDVEIQMLLNKK 276
>gi|154484568|ref|ZP_02027016.1| hypothetical protein EUBVEN_02282 [Eubacterium ventriosum ATCC 27560] >gi|149734416|gb|EDM50333.1| hypothetical protein EUBVEN_02282 [Eubacterium ventriosum ATCC 27560] (302 aa)
Score = 570, Expect = 9.8e-57, Identities = 118/267 (44%), Positives = 167/267 (62%)
  Q:    27 KLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID-ISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           KL +GSHVG   K+ L+GS  E   Y  N FM +TG PQN  RKE+ +  I EA + M   N   ++ IV+HAPY+INL +  K  T  +    L  E+ RT  + S+++VLHPGS + +  +  IN I   +N  +   D+   I +ETMAGKGSE+G NFEE+++I  GV    ++ VC DTCH++D+G D ++D     E+F K +    I V H+NDSKN +G+ KDRH+NIG+G +G+D L +  + E+  N+PKILETPY  D
  S:     2 KLKIGSHVGMSGKDMLLGSAKEAYSYGANVFMAYTGAPQNTRRKEISELKIKEAWEYMAHHN---IDEIVIHAPYIINLANTIKPETYEIAEKFLATELERTEAMGSRIMVLHPGSHVGAGVDAGINQIVKGINNVL-TKDSKACIALETMAGKGSEIGRNFEELARIYDGVVYNDKLRVCFDTCHVNDAGYDLVNDLSGVFEKFDKVIGTDQIGVFHINDSKNVLGAGKDRHENIGFGNIGYDTLRQIIYMEQFENIPKILETPYVKD 266
>gi|13508067|ref|NP_110016.1| endonuclease IV [Mycoplasma pneumoniae M129] >gi|2492911|sp|P75457|END4_MYCPN Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|1674202|gb|AAB96156.1| endonuclease IV [Mycoplasma pneumoniae M129] (286 aa)
Score = 569, Expect = 1.2e-56, Identities = 109/261 (41%), Positives = 169/261 (64%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           LLGS + FK+ +YLVGSV + +      FM+F G P   +R + ++  IDE   LM++ N L    +VVHAPY+IN  S     ++  ++ L  E+   + + +KLIVLHPGSA++  +  A++H+   LN  I A   +VIIC+ETMAGKG+E+G + +++  +++ ++ ++RIGVCLDTCH HDSG D ++  + +E     L   ++KVIHLN+SKN  GS+KDRH N+G G +GFD L+++    ++  +P +LETP
  S:     4 LLGSFISFKSPHYLVGSVRDAVSIKAQAFMIFLGAPHTALRVDPNRMQIDEGHTLMEQHN-LSKSGMVVHAPYIINCASKDPVKQTFAIDVLTREVKLCHAVGAKLIVLHPGSAVEQTQTQALDHLIKVLNTVI-ANTKEVIICLETMAGKGNEIGRDLDQLKYVINHIEQQERIGVCLDTCHFHDSGNDFNNTAEIMETIDTKLGFEFLKVIHLNESKNVCGSKKDRHANLGEGMIGFDNLMRFIAQPQIKQIPIVLETP 262
>gi|194246430|ref|YP_002004069.1| Endonuclease IV [Candidatus Phytoplasma mali] >gi|194246856|ref|YP_002004497.1| Endonuclease IV [Candidatus Phytoplasma mali] >gi|193806787|emb|CAP18214.1| Endonuclease IV [Candidatus Phytoplasma mali] >gi|193807215|emb|CAP18658.1| Endonuclease IV [Candidatus Phytoplasma mali] (286 aa)
Score = 567, Expect = 1.8e-56, Identities = 116/280 (41%), Positives = 178/280 (63%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEK--NPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN-DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD-QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
           L +G  V  K  +   G+V   + +  N FMV++GPP N  R  L+   I EA+ L+K+   NP   +++V HAPY+INL +P    RS  ++ L  EI R N++    +VLHPG+AL   +N AI  IA  +N+  + T +    I +ETMAGKG+E+G  F+E+  I+  ++++ RI VC DTCH+ D+G DI +   + +E F + + L Y+  +H+NDSKN +GS+KDRH N+G G++G   L++  ++    ++PKILETPY D +PIYKQEII + ++
  S:     2 LKIGCFVSLKKPDMFYGAVQAAIAFQANTFMVYSGPPTNTQRVALNNFKISEALTLLKQHQINP---DDLVGHAPYIINLANPNPVNRSFAIDFLTQEIIRFNEMQISQMVLHPGNALRQTKNTAIELIAQGINQIFKNTSHCRTKIALETMAGKGTEIGREFQELKAIIQLIQDQSRIKVCFDTCHVFDAGYDIKNNFLKVIELFDQIIGLKYLSCLHINDSKNCLGSKKDRHQNLGLGQIGLKALMEIIYHPLFLSLPKILETPYIDGQPIYKQEIIMIRTE 282
>gi|188159754|ref|ZP_02998863.1| endodeoxyribonuclease IV [Mycoplasma mycoides subsp. mycoides LC str. GM12] (289 aa)
Score = 567, Expect = 2.0e-56, Identities = 130/284 (45%), Positives = 180/284 (63%)
  Q:    26 NKLLLGSHVGF-KAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTR-SLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN---DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEW 309
           NK+LLG HV   K  NYLVGSV E + Y  N FM+FTGPPQ+ +R   +   I++  +LM     +  +++VVHAPY+IN+ +  +  +    ++ LI EI R  +I    +VLHPGS    +   ++N I     KA++   N   +V I +ETM+GKG+EV    E+   I+  VKNK ++GVCLDTCH+HD+G D+S  D+  E+  +  DL+ +  IHLNDSKN I S KDRH NIGYG VGFD LV    ++  +N+ KILETPY D KP YK EI +L +K +
  S:     2 NKVLLGCHVSMNKQNNYLVGSVNEAISYKANTFMIFTGPPQSTLRTNTNHLYINQMHELMNSYK-IDAKDLVVHAPYIINIANSVDQNKWKFAVDFLIQEIKRCEEIKIPTLVLHPGSHTTGNYKDSLNQII----KALDIVSNYQVNVKIALETMSGKGTEVCSKLEDFKYILDNVKNKDKVGVCLDTCHLHDAGYDLSKWDEFKEQMKQNFDLNKVLCIHLNDSKNMISSHKDRHANIGYGYVGFDTLVNVVFDKDFSNISKILETPYIDKKPPYKIEIEDLLNKTF 285
>gi|152976717|ref|YP_001376234.1| endonuclease IV [Bacillus cereus subsp. cytotoxis NVH 391-98] >gi|189037120|sp|A7GSY1|END4_BACCN Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|152025469|gb|ABS23239.1| apurinic endonuclease Apn1 [Bacillus cereus subsp. cytotoxis NVH 391-98] (298 aa)
Score = 561, Expect = 8.4e-56, Identities = 122/284 (42%), Positives = 181/284 (63%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDIS-DPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWKE 311
           L +GSHV    K  L+ +  E + Y    FM++TG PQN  RK +++  I+   K M+E     ++ I+VHAPY+IN+G + K  T  LG++ L +EI RT  +  +K IVLHPG+ + +  +  I  I   LN+ +   +  V I +ETMAGKG+E G +FEE+++I+ GV   +++ VC DTCH HD+G DI+ D D  L EF K + +  ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L ++PKILETPY     +D KP YK EI  L +  + E
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMEEHG---IKEIIVHAPYIINIGNTTKPETFQLGVDFLRMEIERTEALGVAKQIVLHPGAHVGAGADAGIAQIIKGLNEVL-TPEQTVNIALETMAGKGTECGRSFEEIARIIDGVTYNEKLSVCFDTCHTHDAGYDIANDFDGVLNEFDKIVGIDRLQVLHVNDSKNVRGAAKDRHENIGFGHIGYKALHDIVHHPQLEHIPKILETPYVGEEKKDKKPPYKFEIEMLKNGTFDE 289
>gi|72080404|ref|YP_287462.1| endonuclease IV [Mycoplasma hyopneumoniae 7448] >gi|123645305|sp|Q4A8V0|END4_MYCH7 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|71913528|gb|AAZ53439.1| endonuclease IV [Mycoplasma hyopneumoniae 7448] (276 aa)
Score = 560, Expect = 1.2e-55, Identities = 126/278 (45%), Positives = 174/278 (62%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMR-KELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
           +GSHV F+  +YL G++ E+LE   N  M+F GPPQ+  R K  +    D      K+  P   E+I+VHAPY+IN  SP ++  S     L+ EI + N I +K +VLHPG      + VA   +  +L   +E T N VI+ +ETM+GKGSE+  NFEE+ +IV  V++  RIGVCLDTCH+ D+G D+ +  +  +E  K   ++Y+KVIHLNDS + +GS+KDRH NIG G +G + L K   +   AN+PKILETPY D+KPIY QEI  L  K
  S:     4 IGSHVRFRKPDYLFGAIQESLENKANAAMIFLGPPQSTFRVKPENYKFQDYQKHFFKQIPP---EDIIVHAPYIINPASPIKAQFSNDF--LVKEIEKINYIGAKFLVLHPGFFTSFTKEVAKKQLISSLKSILEKTKN-VILLLETMSGKGSEMCANFEEIVEIVEAVESP-RIGVCLDTCHVWDAGYDLKNFPEFCKELRKTRLINYLKVIHLNDSLSPLGSKKDRHANIGKGFIGLETLRKIVFDPLFANIPKILETPYVDNKPIYDQEIALLLKK 275
>gi|49481293|ref|YP_038343.1| endonuclease IV [Bacillus thuringiensis serovar konkukian str. 97-27] >gi|52141216|ref|YP_085614.1| endonuclease IV [Bacillus cereus E33L] >gi|118479457|ref|YP_896608.1| endonuclease IV [Bacillus thuringiensis str. Al Hakam] >gi|196041579|ref|ZP_03108871.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus cereus NVH0597-99] >gi|196046423|ref|ZP_03113649.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus cereus 03BB108] >gi|166224272|sp|A0RIQ8|END4_BACAH Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|59797681|sp|Q634Q3|END4_BACCZ Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|59797756|sp|Q6HDN3|END4_BACHK Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|49332849|gb|AAT63495.1| deoxyribonuclease IV, phage T4-induced (endonuclease IV) [Bacillus thuringiensis serovar konkukian str. 97-27] >gi|51974685|gb|AAU16235.1| deoxyribonuclease IV, phage T4-induced (endonuclease IV) [Bacillus cereus E33L] >gi|118418682|gb|ABK87101.1| Endonuclease IV [Bacillus thuringiensis str. Al Hakam] >gi|196022893|gb|EDX61574.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus cereus 03BB108] >gi|196027567|gb|EDX66182.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus cereus NVH0597-99] (298 aa)
Score = 558, Expect = 2.1e-55, Identities = 117/263 (44%), Positives = 171/263 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           L +GSHV    K  L+ +  E + Y    FM++TG PQN  RK +++  I+   K M++     +E I+VHAPY+IN+G + K  T  LG++ L +EI RT+ +  +K IVLHPG+ + +  +  I  I   LN+ +   D  V I +ETMAGKG+E G +FEE++KI+ GVK  +++ VC DTCH HD+G DI +D D  L EF K + +  ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L +VPKILETPY
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMEQNG---IEEIIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVL-TPDQTVNIALETMAGKGTECGRSFEEIAKIIDGVKYNEKLSVCFDTCHTHDAGYDIVNDFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLTHVPKILETPY 263
>gi|54020015|ref|YP_115579.1| endonuclease IV [Mycoplasma hyopneumoniae 232] >gi|59797671|sp|Q601Y6|END4_MYCH2 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|53987188|gb|AAV27389.1| endonuclease IV [Mycoplasma hyopneumoniae 232] (276 aa)
Score = 557, Expect = 2.6e-55, Identities = 125/278 (44%), Positives = 175/278 (62%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMR-KELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
           +GSHV F+  +YL G++ E+LE   N  M+F GPPQ+  R K  +  L D      K+  P   E+I+VHAPY+IN  SP ++  S     L+ EI + N I +K +VLHPG      + VA   +  +L   +E T N VI+ +ETM+GKGSE+  NFEE+ +IV  V++  RIG+CLDTCH+ D+G D+ +  +  +E  +   ++Y+KVIHLNDS + +GS+KDRH NIG G +G + L K   +   AN+PKILETPY D+KPIY QEI  L  K
  S:     4 IGSHVRFRKPDYLFGAIQESLENKANAAMIFLGPPQSTFRVKPENYKLQDYQKHFFKQIPP---EDIIVHAPYIINPASPIKAQFSNDF--LVKEIEKINYIGAKFLVLHPGFFTSFTKEVAKKQLISSLKSILEKTKN-VILLLETMSGKGSEMCANFEEIVEIVEAVESP-RIGICLDTCHVWDAGYDLKNFPEFCKEIRRTRLINYLKVIHLNDSLSPLGSKKDRHANIGKGFIGLESLRKIIFDPLFANIPKILETPYVDNKPIYDQEIALLLKK 275
>gi|148377761|ref|YP_001256637.1| endonuclease IV [Mycoplasma agalactiae PG2] >gi|148291807|emb|CAL59197.1| Endonuclease IV [Mycoplasma agalactiae PG2] (278 aa)
Score = 557, Expect = 2.8e-55, Identities = 117/272 (43%), Positives = 171/272 (62%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           LGSH+ FK+ NYL+G+  E++    NC M++ G PQ   R  +++   +E   L K    +  ++I+VHAPY++N  S   S     ++ L+ EI + N I +K +VLHPGS        +++    ++ + +  T  DV+ICVETMAGKG+EVGINF++++  +  ++N  R  VCLDTCH+ D+G DI   ++   E +KY  L +IKVIHLNDSKN +GS KDRH NI  G +G + L K+ H+    N+P ILETP+ D+KPIY QEI
  S:     4 LGSHISFKSPNYLLGAAAESVNNKANCMMIYLGAPQTTKRVSVEKYKYNEY--LEKYSKLITPDDIIVHAPYIVNPSSV--SKNKFAIDFLVQEIEKMNYIGAKYLVLHPGSYTTFSVQESLDTFIASVKQILSRT-KDVVICVETMAGKGAEVGINFDQINYFIHKIRND-RFAVCLDTCHIFDAGYDIRKYEEFKAEINKYNLLPHIKVIHLNDSKNSLGSHKDRHANIDKGFIGLETLAKFVHDPDFDNIPIILETPWVDNKPIYDQEI 269
>gi|166995867|ref|ZP_02262327.1| endonuclease IV [Bacillus cereus AH820] >gi|196034953|ref|ZP_03102360.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus cereus W] >gi|195992492|gb|EDX56453.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus cereus W] (298 aa)
Score = 557, Expect = 2.9e-55, Identities = 116/261 (44%), Positives = 170/261 (65%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           +GSHV    K  L+ +  E + Y    FM++TG PQN  RK +++  I+   K M++     +E I+VHAPY+IN+G + K  T  LG++ L +EI RT+ +  +K IVLHPG+ + +  +  I  I   LN+ +   D  V I +ETMAGKG+E G +FEE++KI+ GVK  +++ VC DTCH HD+G DI +D D  L EF K + +  ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L +VPKILETPY
  S:     4 IGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMEQNG---IEEIIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVL-TPDQTVNIALETMAGKGTECGRSFEEIAKIIDGVKYNEKLSVCFDTCHTHDAGYDIVNDFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLTHVPKILETPY 263
>gi|71893417|ref|YP_278863.1| endonuclease IV [Mycoplasma hyopneumoniae J] >gi|123646075|sp|Q4AAX4|END4_MYCHJ Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|71851544|gb|AAZ44152.1| endonuclease IV [Mycoplasma hyopneumoniae J] (276 aa)
Score = 557, Expect = 3.1e-55, Identities = 125/278 (44%), Positives = 175/278 (62%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMR-KELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
           +GSHV F+  +YL G++ E+LE   N  M+F GPPQ+  R K  +  L D      K+  P   E+I+VHAPY+IN  SP ++  S     L+ EI + N I +K +VLHPG      + VA   +  +L   +E T N VI+ +ETM+GKGSE+  NFEE+ +IV  V++  RIG+CLDTCH+ D+G D+ +  +  +E  +   ++Y+KVIHLNDS + +GS+KDRH NIG G +G + L K   +   AN+PKILETPY D+KPIY QEI  L  K
  S:     4 IGSHVRFRKPDYLFGAIQESLENKANTAMIFLGPPQSTFRVKPENYKLQDYQKHFFKQIPP---EDIIVHAPYIINPASPIKAQFSNDF--LVKEIEKINYIGAKFLVLHPGFFTSFTKEVAKKQLISSLKSILEKTKN-VILLLETMSGKGSEMCANFEEIVEIVEAVESP-RIGICLDTCHVWDAGYDLKNFPEFCKEIRRTRLINYLKVIHLNDSLSPLGSKKDRHANIGKGFIGLESLRKIIFDPLFANIPKILETPYVDNKPIYDQEIALLLKK 275
>gi|154504603|ref|ZP_02041341.1| hypothetical protein RUMGNA_02109 [Ruminococcus gnavus ATCC 29149] >gi|153795085|gb|EDN77505.1| hypothetical protein RUMGNA_02109 [Ruminococcus gnavus ATCC 29149] (301 aa)
Score = 556, Expect = 3.8e-55, Identities = 120/261 (45%), Positives = 156/261 (59%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           LGSHVG   K  L+GS  E + Y  N FM +TG PQN  RKE+ +  I  A + MKE     ++ I+VHAPY+INLG S K  T  L +  L  EI RT    S  +VLHPGS + +  +  I  I   LN  + A D    I +ETMAGKGSE+G  FEE+++I  GV    ++ VC DTCH  DSG DI    D  ++EF + +    I V H+NDSKN  G+ KDRH NIG+G +GFD +    H++   ++PKILETPY
  S:     3 LGSHVGMSGKEMLLGSAKEAVSYGANTFMFYTGAPQNTRRKEISELNISSAWEYMKEHG---IDEIIVHAPYIINLGNSVKPETFELAVEFLAKEIERTAACKSHTLVLHPGSHVGAGTDAGIRQIIKGLNAVLTA-DTPCHIALETMAGKGSEIGRTFEELAQIYDGVVYNDKLRVCFDTCHTSDSGYDIIHHFDDVIDEFDRLIGKDQIAVFHINDSKNIPGAAKDRHANIGFGHIGFDAIHHIVHHKDFMDIPKILETPY 261
>gi|116492873|ref|YP_804608.1| endonuclease IV [Pediococcus pentosaceus ATCC 25745] >gi|122265663|sp|Q03F56|END4_PEDPA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|116103023|gb|ABJ68166.1| Endonuclease IV [Pediococcus pentosaceus ATCC 25745] (296 aa)
Score = 554, Expect = 5.6e-55, Identities = 112/266 (42%), Positives = 171/266 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP-DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           +++GSHV    +   +GSV  ++E   N  M++TG PQN  RK ++   I E   L+ E +    +++VVHAPY++NLG+  K  +    +  L  E+ R + + +  +VLHPGS + +  + AI  I + LN+ I    N V I +ETMAGKG+EV  NFE++ +I++GV++ +++ VC DTCH +D+G D+ +  D  ++EF + + L  I VIHLNDSKNE+GS KDRH+N+G+G +GF  L   A+ +K  NVPKILETP+  D
  S:     1 MIIGSHVSMSGRKMFLGSVETSIENGANALMIYTGAPQNTRRKAIEDLRIPEGRALLTEHD---FKDVVVHAPYIVNLGNTFKPESFKFAVEFLKEEVKRADALGASQLVLHPGSHVGAGPDAAIASITEGLNQIITPEQN-VKIALETMAGKGTEVATNFEQIQQIITGVEHNEKLSVCFDTCHTNDAGYDVKNHFDDVMDEFDQIIGLQKIGVIHLNDSKNEMGSHKDRHENLGFGTIGFKALHYIANFDKFQNVPKILETPWVKD 264
>gi|65321659|ref|ZP_00394618.1| COG0648: Endonuclease IV [Bacillus anthracis str. A2012] (292 aa)
Score = 553, Expect = 7.0e-55, Identities = 116/263 (44%), Positives = 171/263 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           L +GSHV    K  L+ +  E + Y    FM++TG PQN  RK +++  I+   K M++     +E I+VHAPY+IN+G + K  T  LG++ L +EI RT+ +  +K IVLHPG+ + +  +  I  I   LN+ +   D  V I +ETMAGKG+E G +FEE++KI+ GVK  +++ VC DTCH HD+G DI ++ D  L EF K + +  ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L +VPKILETPY
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMEQNG---IEEIIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVL-TPDQTVNIALETMAGKGTECGRSFEEIAKIIDGVKYNEKLSVCFDTCHTHDAGYDIVNNFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLTHVPKILETPY 263
>gi|30264356|ref|NP_846733.1| endonuclease IV [Bacillus anthracis str. Ames] >gi|47529803|ref|YP_021152.1| endonuclease IV [Bacillus anthracis str. 'Ames Ancestor'] >gi|49187183|ref|YP_030435.1| endonuclease IV [Bacillus anthracis str. Sterne] >gi|165872072|ref|ZP_02216712.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis str. A0488] >gi|167634543|ref|ZP_02392863.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis str. A0442] >gi|167638654|ref|ZP_02396930.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis str. A0193] >gi|170687520|ref|ZP_02878737.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis str. A0465] >gi|170707435|ref|ZP_02897889.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis str. A0389] >gi|177655071|ref|ZP_02936737.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis str. A0174] >gi|190566029|ref|ZP_03018948.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis Tsiankovskii-I] >gi|39931061|sp|Q81LV1|END4_BACAN Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|30259014|gb|AAP28219.1| endonuclease IV [Bacillus anthracis str. Ames] >gi|47504951|gb|AAT33627.1| endonuclease IV [Bacillus anthracis str. 'Ames Ancestor'] >gi|49181110|gb|AAT56486.1| endonuclease IV [Bacillus anthracis str. Sterne] >gi|164712203|gb|EDR17740.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis str. A0488] >gi|167513502|gb|EDR88872.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis str. A0193] >gi|167529995|gb|EDR92730.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis str. A0442] >gi|170127679|gb|EDS96552.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis str. A0389] >gi|170668715|gb|EDT19461.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis str. A0465] >gi|172080332|gb|EDT65421.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis str. A0174] >gi|190562948|gb|EDV16914.1| deoxyribonuclease IV (phage-T(4)-induced) [Bacillus anthracis Tsiankovskii-I] (298 aa)
Score = 553, Expect = 8.6e-55, Identities = 116/263 (44%), Positives = 171/263 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           L +GSHV    K  L+ +  E + Y    FM++TG PQN  RK +++  I+   K M++     +E I+VHAPY+IN+G + K  T  LG++ L +EI RT+ +  +K IVLHPG+ + +  +  I  I   LN+ +   D  V I +ETMAGKG+E G +FEE++KI+ GVK  +++ VC DTCH HD+G DI ++ D  L EF K + +  ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L +VPKILETPY
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMEQNG---IEEIIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVL-TPDQTVNIALETMAGKGTECGRSFEEIAKIIDGVKYNEKLSVCFDTCHTHDAGYDIVNNFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLTHVPKILETPY 263
>gi|78100962|pdb|1XP3|A Chain A, Crystal Structure Of Endonuclease Iv (Ba4508) From Bacillus Anthracis At 2.57a Resolution. (307 aa)
Score = 552, Expect = 1.1e-54, Identities = 115/263 (43%), Positives = 171/263 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           L +GSHV    K  L+ +  E + Y    FM++TG PQN  RK +++  I+   K M++     +E I++HAPY+IN+G + K  T  LG++ L +EI RT+ +  +K IVLHPG+ + +  +  I  I   LN+ +   D  V I +ETMAGKG+E G +FEE++KI+ GVK  +++ VC DTCH HD+G DI ++ D  L EF K + +  ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L +VPKILETPY
  S:    11 LKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMEQNG---IEEIIIHAPYIINVGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVL-TPDQTVNIALETMAGKGTECGRSFEEIAKIIDGVKYNEKLSVCFDTCHTHDAGYDIVNNFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLTHVPKILETPY 272
>gi|163942043|ref|YP_001646927.1| endonuclease IV [Bacillus weihenstephanensis KBAB4] >gi|163864240|gb|ABY45299.1| apurinic endonuclease Apn1 [Bacillus weihenstephanensis KBAB4] (298 aa)
Score = 551, Expect = 1.5e-54, Identities = 116/263 (44%), Positives = 171/263 (65%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID-ISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           L +GSHV    K  L+ +  E + Y    FM++TG PQN  RK +++  I+   K M+      +E I+VHAPY+INLG + K  T  LG++ L +EI RT+ +  +K IVLHPG+ + +  +  I  I   LN+ +   +  V I +ETMAGKG+E G +FEE++KI+ GVK  +++ VC DTCH HD+G D ++D D  L EF K + ++ ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L +VPKILETPY
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMELNG---IEEIIVHAPYIINLGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVL-TPEQTVNIALETMAGKGTECGRSFEEIAKIIDGVKYNEKLSVCFDTCHTHDAGYDLVNDFDGVLNEFDKIVGINRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLTHVPKILETPY 263
>gi|42560664|ref|NP_975115.1| endodeoxyribonuclease IV [Mycoplasma mycoides subsp. mycoides SC str. PG1] >gi|59797774|sp|Q6MUC7|END4_MYCMS Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|42492160|emb|CAE76757.1| endodeoxyribonuclease IV [Mycoplasma mycoides subsp. mycoides SC str. PG1] (289 aa)
Score = 549, Expect = 2.2e-54, Identities = 125/284 (44%), Positives = 174/284 (61%)
  Q:    26 NKLLLGSHVGF-KAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTR-SLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEW 309
           +K+LLG HV   K  NYLVGSV E + Y  N FM+FTGPPQ+ +R   +   I++  +LM     +  +++VVHAPY+IN+ +  +  +    ++ LI EI R  +I    +VLHPGS    +   ++N I   LN  +     +V I +ETM+GKG+EV    E+   I+  VKNK ++GVCLDTCH+HD+G D+S   +  E+  +   L  +  IHLNDSKN I S KDRH NIGYG VGFD LV    ++  +N+ KILETPY D  P YK EI +L +K +
  S:     2 DKILLGCHVSMNKQNNYLVGSVNEAISYKANTFMIFTGPPQSTLRTNTNHLYINQMHELMNSYK-IDAKDLVVHAPYIINIANSVDQNKWKFTVDFLIQEIKRCEEIKIPTLVLHPGSYTTGNYKDSLNQIIKALN-IVSNYQVNVKIALETMSGKGTEVCSRLEDFKYILDNVKNKDKVGVCLDTCHLHDAGYDLSKWTEFKEQMKQNFSLDKVLCIHLNDSKNMISSHKDRHANIGYGYVGFDTLVNVVFDKDFSNISKILETPYIDKTPPYKIEIEDLLNKTF 285
>gi|168163714|ref|ZP_02598947.1| apurinic endonuclease Apn1 [Bacillus cereus H3081.97] (298 aa)
Score = 548, Expect = 3.4e-54, Identities = 116/263 (44%), Positives = 169/263 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           L +GSHV    K  L+ +  E + Y    FM++TG PQN  RK +++  I+   K M++     +E I+VHAPY+IN+G + K  T  LG++ L +EI RT  +  +K IVLHPG+ + +  +  I  I   LN+ +   D  V I +ETMAGKG+E G +FEE++KI+ GV   +++ VC DTCH HD+G DI +D D  L EF K + +  ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L +VPKILETPY
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMEQNG---IEEIIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTLALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVL-TPDQTVNIALETMAGKGTECGRSFEEIAKIIDGVTYNEKLSVCFDTCHTHDAGYDIVNDFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLMHVPKILETPY 263
>gi|30022364|ref|NP_833995.1| endonuclease IV [Bacillus cereus ATCC 14579] >gi|168136458|ref|ZP_02579687.1| endonuclease IV [Bacillus cereus B4264] >gi|39931051|sp|Q818H3|END4_BACCR Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|29897921|gb|AAP11196.1| Endonuclease IV [Bacillus cereus ATCC 14579] (298 aa)
Score = 547, Expect = 3.9e-54, Identities = 116/263 (44%), Positives = 170/263 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           L +GSHV    K  L+ +  E + Y    FM++TG PQN  RK +++  I+   K M+      +E I+VHAPY+IN+G + K  T  LG++ L +EI RT+ +  +K IVLHPG+ + +  +  I  I   LN+ +   +  V I +ETMAGKG+E G +FEE++KI+ GVK  +++ VC DTCH HD+G DI +D D  L EF K + +  ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L +VPKILETPY
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMELNG---IEEIIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVL-TPEQTVNIALETMAGKGTECGRSFEEIAKIIDGVKYNEKLSVCFDTCHTHDAGYDIVNDFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLMHVPKILETPY 263
>gi|47567846|ref|ZP_00238554.1| endonuclease IV [Bacillus cereus G9241] >gi|47555523|gb|EAL13866.1| endonuclease IV [Bacillus cereus G9241] (298 aa)
Score = 547, Expect = 4.1e-54, Identities = 116/263 (44%), Positives = 169/263 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           L +GSHV    K  L+ +  E + Y    FM++TG PQN  RK +++  I+   K M+      +E I+VHAPY+IN+G + K  T  LG++ L +EI RT+ +  +K IVLHPG+ + +  +  I  I   LN+ +   D  V I +ETMAGKG+E G +FEE++KI+ GV   +++ VC DTCH HD+G DI +D D  L EF K + +  ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L +VPKILETPY
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMELNG---IEEIIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVL-TPDQTVNIALETMAGKGTECGRSFEEIAKIIDGVTYNEKLSVCFDTCHTHDAGYDIVNDFDGVLNEFDKTVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLMHVPKILETPY 263
>gi|75762209|ref|ZP_00742102.1| Endonuclease IV [Bacillus thuringiensis serovar israelensis ATCC 35646] >gi|74490294|gb|EAO53617.1| Endonuclease IV [Bacillus thuringiensis serovar israelensis ATCC 35646] (298 aa)
Score = 547, Expect = 4.3e-54, Identities = 116/263 (44%), Positives = 170/263 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           L +GSHV    K  L+ +  E + Y    FM++TG PQN  RK +++  I+   K M+      +E I+VHAPY+IN+G + K  T  LG++ L +EI RT+ +  +K IVLHPG+ + +  +  I  I   LN+ +   +  V I +ETMAGKG+E G +FEE++KI+ GVK  +++ VC DTCH HD+G DI +D D  L EF K + +  ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L +VPKILETPY
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMELNG---IEEIIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVL-TPEQTVNIALETMAGKGTECGRSFEEIAKIIDGVKYNEKLSVCFDTCHTHDAGYDIVNDFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHVVHHPQLMHVPKILETPY 263
>gi|83319329|ref|YP_424056.1| endonuclease IV [Mycoplasma capricolum subsp. capricolum ATCC 27343] >gi|123535992|sp|Q2ST57|END4_MYCCT Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|83283215|gb|ABC01147.1| endonuclease IV [Mycoplasma capricolum subsp. capricolum ATCC 27343] (289 aa)
Score = 547, Expect = 4.5e-54, Identities = 127/284 (44%), Positives = 177/284 (62%)
  Q:    26 NKLLLGSHVGF-KAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTR-SLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN---DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEW 309
           +K+LLG HV   K  NYLVGSV E + Y  N FM+FTGPPQ+ +R   +   I++  +LM     +  +++VVHAPY+IN+ +  +  +    +N LI EI R  +I    +VLHPGS    +   ++N I     KA++   N   +V I +ETM+GKG+EV    E+   I+  VKNK ++GVCLDTCH+HD+G D+S   +  E+  +  +L  +  IHLNDSKN I S KDRH NIGYG VGFD LV    ++  +N+ KILETPY D K  YK EI +L +K +
  S:     2 DKVLLGCHVSMNKQNNYLVGSVNEAISYKANTFMIFTGPPQSTLRTNTNHLYINQMHELMNSYK-IDAKDLVVHAPYIINIANSVDQNKWEFAVNFLIQEIKRCEEIKIPTLVLHPGSYTTGNYKDSLNQII----KALDMVSNYQVNVKIALETMSGKGTEVCSKLEDFKYILDNVKNKDKVGVCLDTCHLHDAGYDLSKWTEFKEQIKQNFNLDKVLCIHLNDSKNMISSHKDRHANIGYGFVGFDTLVNVVFDKDFSNISKILETPYIDKKAPYKIEIEDLLNKTF 285
>gi|163791441|ref|ZP_02185850.1| endonuclease IV [Carnobacterium sp. AT7] >gi|159873305|gb|EDP67400.1| endonuclease IV [Carnobacterium sp. AT7] (300 aa)
Score = 546, Expect = 4.7e-54, Identities = 120/282 (42%), Positives = 170/282 (60%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEW 309
           +LLGSHV    K  L+GS  E   Y+   FM++TG PQN  RK ++   I +    M E N   L  +VVHAPY+IN G+  K    +  +  L  EI R   + ++ I +HPG+ + +     I  I   LN+ +   D    I +ETMAGKG+E+G +FEE++KI+ GV    ++ V +DTCH++D+G ++  D D  LEEF K + L  +KV+H+NDSKN  GS KDRH NIG+G +GFD L K  H+ +L ++PKILETPY     +D K  Y  EI  L  + +
  S:     2 VLLGSHVSMGGKKMLLGSAEEAASYNAETFMIYTGAPQNTRRKLVEDMNIPKGTAFMSENN---LSKMVVHAPYIINFGNTIKPENFAFAIEFLRAEIVRAEALGARQITMHPGAHVGAGSEAGIAQIIKGLNEVLH-KDQLAQIALETMAGKGTEIGRDFEELAKIIEGVSLNDKLSVTMDTCHINDAGYNVKEDFDGVLEEFDKIIGLERLKVVHVNDSKNPQGSHKDRHANIGFGTIGFDALNKVVHHPQLTDLPKILETPYVGEDKKDKKAPYGYEIKMLKEQTF 286
>gi|29376286|ref|NP_815440.1| endonuclease IV [Enterococcus faecalis V583] >gi|39931088|sp|Q834D0|END4_ENTFA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|29343749|gb|AAO81510.1| endonuclease IV [Enterococcus faecalis V583] (297 aa)
Score = 546, Expect = 5.3e-54, Identities = 122/282 (43%), Positives = 170/282 (60%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP-DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEW 309
           +LLGSHV    K  L+GS  E   Y    FM++TG PQN  RK +++  I+     MKE N   L NIVVHAPY+INLG+  K       ++ L  EI R   + +  I LHPG+ + +     I  I   LN+ +   +    I +ETMAGKG+E+G  F+E++ I+ GV    ++ V LDTCH++D+G ++ D  D  L EF K + L  +KVIH+NDSKN +GS KDRH NIG+G +GF+ L    H+EKL  +PKILETPY     ++ K  Y  EI  L ++ +
  S:     1 MLLGSHVSMSGKKMLLGSAEEAASYGSTTFMIYTGAPQNTRRKPIEEMNIEAGQAFMKEHN---LSNIVVHAPYIINLGNTIKTENFGFAVDFLRQEIERAQALGATQITLHPGAHVGAGPEAGIKQIVKGLNEVL-WKEQIPQIALETMAGKGTEIGRTFDELAAIIDGVTLNDKLSVTLDTCHINDAGYNVKDDFDGVLVEFDKIIGLDRLKVIHVNDSKNPMGSHKDRHANIGFGTIGFEALNGVVHHEKLTALPKILETPYVGEDKKNKKAPYGFEIAMLKNQTF 285
>gi|168140275|ref|ZP_02583504.1| endonuclease IV [Bacillus cereus G9842] (298 aa)
Score = 546, Expect = 5.3e-54, Identities = 116/263 (44%), Positives = 170/263 (64%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           L +GSHV    K  L+ +  E + Y    FM++TG PQN  RK +++  I+   K M+      +E I+VHAPY+IN+G + K  T  LG++ L +EI RT+ +  +K IVLHPG+ + +  +  I  I   LN+ +   +  V I +ETMAGKG+E G +FEE++KI+ GVK  +++ VC DTCH HD+G DI +D D  L EF K + +  ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L +VPKILETPY
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMELNG---IEEIIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVL-TPEQTVNIALETMAGKGTECGRSFEEIAKIIDGVKYNEKLSVCFDTCHTHDAGYDIVNDFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLMHVPKILETPY 263
>gi|166031103|ref|ZP_02233932.1| hypothetical protein DORFOR_00788 [Dorea formicigenerans ATCC 27755] >gi|166028950|gb|EDR47707.1| hypothetical protein DORFOR_00788 [Dorea formicigenerans ATCC 27755] (303 aa)
Score = 543, Expect = 1.1e-53, Identities = 121/284 (42%), Positives = 168/284 (59%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-------RDDKPIYKQEIINLNSKEWKE 311
           L LGSHV    K+ L+GS  E   Y  N FM +TG PQN  RK++ +  ID A   M EKN   + +IVVHAPY+INLG+  K  T  L +  L  EI+R     S+ ++LHPG+ + +     +  +   LN+ +   D  + I +ETMAGKGSE+G +FEE++ I  GV    ++ VC DTCH HDSG DI  + D  ++EF   +    I V H+NDSKN  G++KDRH N+G G++GFD L    H+     +PKILETPY       +     YK EI  L + ++ +
  S:     3 LKLGSHVSMSGKSMLLGSAKEAESYGANTFMFYTGAPQNTKRKDISELNIDAAWNYMNEKN---ISDIVVHAPYIINLGNTVKPETYELAVEFLAKEIDRAAACKSQTLILHPGAHVGAGVETGLQQVIKGLNEVL-TKDTPLHIALETMAGKGSELGRSFEELAAIYDGVVYSDKLRVCFDTCHTHDSGYDIRGNFDGVIDEFDHLIGKDQIAVFHINDSKNVCGAKKDRHANLGTGEIGFDALSYIVHHPDFEQIPKILETPYIPSPTKEKKSYAPYKYEIAMLRASQFDK 291
>gi|39938940|ref|NP_950706.1| endonuclease IV [Onion yellows phytoplasma OY-M] >gi|59797782|sp|Q6YQC1|END4_ONYPE Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|39722049|dbj|BAD04539.1| endonuclease IV [Onion yellows phytoplasma OY-M] (292 aa)
Score = 541, Expect = 2.0e-53, Identities = 116/282 (41%), Positives = 180/282 (63%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN-DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP-DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEW 309
           L LGSHV  K  +   G++   + Y  N  MV++G PQN +R + ++  I +A+++++  N L L N+V HAPY+INL +P E+ R+  ++ L  E+ R   +    +VLHPG+ L ++    I+ IA +L+   E T +    + +ETMAGKG+E+G N EE+ +I + VKN  R+  CLDTCH+ D+G D+ +  ++ +++    L    I VIH+NDSKNE  S KDRH+NIG+GK+GF+ L+K  ++   A +PKILETPY +DK  YK+EI  + +K +
  S:     2 LFLGSHVAMKKPHNFQGAIQTAISYGANALMVYSGAPQNTIRTKTEELKIKQALEIVQNNN-LSLNNLVGHAPYIINLANPDETKRAFAIDFLSQELERFAAMKINKMVLHPGNYLKTNPQEGISLIAQSLDLIFEKTKHLKTQVALETMAGKGTEIGKNLEELQQIRTQVKNNTRVSFCLDTCHLFDAGYDLKENLEEIIQKIDSILGFQNISVIHINDSKNECNSHKDRHENIGFGKIGFETLLKIIYHRAFACIPKILETPYINDKAPYKREIEMIKAKAF 284
>gi|69249143|ref|ZP_00604880.1| AP endonuclease, family 2 [Enterococcus faecium DO] >gi|68194269|gb|EAN08788.1| AP endonuclease, family 2 [Enterococcus faecium DO] (300 aa)
Score = 539, Expect = 3.4e-53, Identities = 117/270 (43%), Positives = 161/270 (59%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY--RDDKPIY 297
           +LLGSHV    K  L+G+  E   Y  + FM++TG PQN  RK +++  ID     M E     L NIVVHAPY+INLG+  K       +  L  EI R   + +  I LHPG+ + +     I  I + LN+ +   +    I +ETMAGKG+E+G  FEE+++I+ GVK  +++ V  DTCH +D+G +I  D    +EEF K + L  +KV+H+NDSKN  GS KDRH NIG+G +GFD L K  H+    N+ KILETPY  +D K  Y
  S:     1 MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKAIEEMNIDAGKAYMAENG---LTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALGATQITLHPGAHVGAGTEAGIARIIEGLNEVL-TKEQTAQIALETMAGKGTEIGRTFEELAQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSKNPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAY 270
>gi|163815920|ref|ZP_02207290.1| hypothetical protein COPEUT_02100 [Coprococcus eutactus ATCC 27759] >gi|158448730|gb|EDP25725.1| hypothetical protein COPEUT_02100 [Coprococcus eutactus ATCC 27759] (301 aa)
Score = 534, Expect = 1.2e-52, Identities = 113/266 (42%), Positives = 162/266 (60%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           L LG HVG   K+ ++GSV + + +  N FM++TG PQN  RK++ +  I EA +LM +     +E  VVHAPY+INL +    +T  + +  L  E+ R   + S  IVLHPGS +    +  I  I   LN+ + A D    I +ETMAGKGSE+G +FEE+++I  GV    ++ VC DTCH  D+G DI  D D  +E+F + +  + I   H+NDSKNE G+ KDRH+N G+GK+GF+ L+   ++     VPKILE+PY  D
  S:     2 LKLGCHVGMSGKDMMLGSVRDAVSFGANTFMLYTGAPQNTRRKDISELKIQEAHELMAQHG---IEEFVVHAPYIINLANTVNPATYEIAVEFLAKELERATAMGSHTIVLHPGSHVGEGVDKGIASIVKGLNEVLTA-DTTCHIALETMAGKGSEIGRSFEELARIYDGVNYNDKLRVCFDTCHTSDAGYDIIHDFDGVMEKFDRLIGKAQIAAFHMNDSKNEPGAAKDRHENFGFGKIGFEPLMYIMNHTDFMEVPKILESPYIKD 265
>gi|81428478|ref|YP_395478.1| endonuclease IV [Lactobacillus sakei subsp. sakei 23K] >gi|123564334|sp|Q38XB2|END4_LACSS Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|78610120|emb|CAI55169.1| Endodeoxyribonuclease type IV [Lactobacillus sakei subsp. sakei 23K] (300 aa)
Score = 534, Expect = 1.4e-52, Identities = 122/282 (43%), Positives = 168/282 (59%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY--RDDK---PIYKQEIINLNSKEW 309
           +LLGSHV  K K  L+GS  +  E+  N FM++TG PQN  RK +++  I  A  L+  KN   L  IVVHAPY++NLG+  K       +  L  E+ R   + +  IVLHPG+ + +  +  I  I   LN+ +   D    I +ETMAGKG+EVG  FEE+++++ GV    ++ V  DTCH  D+G +I  D D  L EF   + L  +KVIHLNDSKN  G+ KDRH NIG+G++GFD L     + +L +VPKI+ETPY  +D K     Y  EI  L   E+
  S:     1 MLLGSHVSMKGKEMLLGSAQQAAEFGANTFMIYTGAPQNTRRKPIEELNIPAAQALIAAKN---LGPIVVHAPYIVNLGNTVKPENFKFAIEFLQQEVIRAEALGASQIVLHPGAHVGAGADAGIKQIIKGLNEILRP-DQTAQIALETMAGKGTEVGRRFEEIAQMIDGVTLNDKLSVTFDTCHTSDAGYNIREDFDGVLNEFDHIIGLDRLKVIHLNDSKNPQGAHKDRHANIGFGEIGFDALHGVVTHPQLVDVPKIMETPYVGKDKKHNFAPYAYEIAMLKKGEF 285
>gi|153814086|ref|ZP_01966754.1| hypothetical protein RUMTOR_00294 [Ruminococcus torques ATCC 27756] >gi|145848482|gb|EDK25400.1| hypothetical protein RUMTOR_00294 [Ruminococcus torques ATCC 27756] (295 aa)
Score = 532, Expect = 2.0e-52, Identities = 112/253 (44%), Positives = 155/253 (61%)
  Q:    38 AKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
            K  L+GS  E + Y  + FM +TG PQN  RKE+++  ID A + MKE     ++ I+VHAPY+INLG+  K  T SL +  L  EI+RT    S  ++LHPG+ +    ++    I   LN+ +   D D  + +ETMAGKGSE+G  FEE+++I  GVK   ++ VC DTCH  DSG DI    D  +EEF + +    I V H+NDSKN  G+ KDRH+NIG+G +GF+ +    H+    +VPKILETPY
  S:     3 GKEMLLGSAKEAVSYGADTFMFYTGAPQNTRRKEIEELNIDPAWEYMKEHG---IQEIIVHAPYIINLGNAVKPETFSLAVEFLAKEIDRTVSCRSHTLILHPGAHVGEGVSIGTEQIIKGLNEVL-TQDMDCCVALETMAGKGSEIGRTFEELARIYDGVKYSDKLRVCFDTCHTSDSGYDIIHHFDDVIEEFDRIIGKDQIAVFHINDSKNVPGAAKDRHENIGFGHIGFEAINYIVHHADFRDVPKILETPY 253
>gi|110005063|emb|CAK99393.1| probable endonuclease iv protein [Spiroplasma citri] (308 aa)
Score = 532, Expect = 2.3e-52, Identities = 119/289 (41%), Positives = 183/289 (63%)
  Q:    23 MSKNKLLLGSHVGF-KAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP-DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK----PIYKQEIINLNSKEWKE 311
           M    L++GSHV   K +NYL+G++ E+L  + N  M++TGPPQN +R   +Q  I E  + +K K+   + NI++HAPY+INL  +   ST  + +  L  EI R ++I  K IVLHPGS + +   V ++ I + LN  +   +    I +ETMAGKGSE+G +F ++  I+  VK   ++GVC DTCHMHD+G  +++  D  + EF + + L+ +  +H+NDSKN + + KDRH+NIGYG +GF+ L+K  ++ KL  + KILETPY  +K      YK EI  + +K + +
  S:     1 MKDYNLIIGSHVSMNKQQNYLLGALNESLNNNANAMMIYTGPPQNTIRVSTEQFFIPEFYQQLK-KHHFDINNIIIHAPYIINLANTTNPSTFEIAVEFLKNEITRADEIGIKTIVLHPGSGVGAPEQVGLDQIIEGLNLVL-TPNQKAKIALETMAGKGSELGTSFAQLKYIIDNVKLNDKLGVCWDTCHMHDAGYRLTEALDDIIIEFEQLIGLNRLLCLHINDSKNPLNAHKDRHENIGYGYLGFETLLKIIYHPKLDGMIKILETPYVGEKKHAVAPYKDEIAMIKAKNFTD 294
>gi|66880113|ref|ZP_00405098.1| COG0648: Endonuclease IV [Mycoplasma genitalium G-37] (282 aa)
Score = 531, Expect = 2.6e-52, Identities = 115/278 (41%), Positives = 164/278 (58%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR--DDKPIYKQEIINLNS 306
           LLGS + FKA NY V S  + +  D    MVF GPP +  R   ++       +L+K KN +    +VVHAPY+IN  S     +   ++ L  EI   N   +  +VLHPGSA+    N A++++   LN+ I  T   VI C+ETMAGKG+E+G +  E+  ++  + +K RIGVCLDTCH HDSGID SD        +  L   ++KVIHLN+SKN  GS+KDRH NI  G +GF+ L+K+  + ++ ++P ILETP    +   IY++EI  + S
  S:     4 LLGSFISFKAPNYFVQSAQDAIAIDATALMVFLGPPHSAYRVPFNKMQFSLGYELLKTKN-INSNGLVVHAPYIINCASKDPLKQQNAISVLTNEIQLCNLAGAHYLVLHPGSAVAQTTNEALDNLVKVLNQVINKTKTTVI-CLETMAGKGNEIGRDLTELKYVIDRIVDKDRIGVCLDTCHFHDSGIDFSDLTGVFNTITTKLGFEFLKVIHLNESKNNCGSKKDRHANINAGMIGFENLMKFISHPQIKDLPIILETPSTSLNYPTIYREEISQIRS 281
>gi|12045090|ref|NP_072901.1| apurinic endonuclease (APN1) [Mycoplasma genitalium G37] >gi|1352365|sp|P47477|END4_MYCGE Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|3844839|gb|AAC71456.1| apurinic endonuclease (APN1) [Mycoplasma genitalium G37] >gi|166078818|gb|ABY79436.1| apurinic endonuclease (APN1) [synthetic Mycoplasma genitalium JCVI-1.0] (291 aa)
Score = 531, Expect = 2.7e-52, Identities = 115/278 (41%), Positives = 164/278 (58%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR--DDKPIYKQEIINLNS 306
           LLGS + FKA NY V S  + +  D    MVF GPP +  R   ++       +L+K KN +    +VVHAPY+IN  S     +   ++ L  EI   N   +  +VLHPGSA+    N A++++   LN+ I  T   VI C+ETMAGKG+E+G +  E+  ++  + +K RIGVCLDTCH HDSGID SD        +  L   ++KVIHLN+SKN  GS+KDRH NI  G +GF+ L+K+  + ++ ++P ILETP    +   IY++EI  + S
  S:     4 LLGSFISFKAPNYFVQSAQDAIAIDATALMVFLGPPHSAYRVPFNKMQFSLGYELLKTKN-INSNGLVVHAPYIINCASKDPLKQQNAISVLTNEIQLCNLAGAHYLVLHPGSAVAQTTNEALDNLVKVLNQVINKTKTTVI-CLETMAGKGNEIGRDLTELKYVIDRIVDKDRIGVCLDTCHFHDSGIDFSDLTGVFNTITTKLGFEFLKVIHLNESKNNCGSKKDRHANINAGMIGFENLMKFISHPQIKDLPIILETPSTSLNYPTIYREEISQIRS 281
>gi|116333389|ref|YP_794916.1| endonuclease IV [Lactobacillus brevis ATCC 367] >gi|116098736|gb|ABJ63885.1| Endonuclease IV [Lactobacillus brevis ATCC 367] (309 aa)
Score = 531, Expect = 2.8e-52, Identities = 116/262 (44%), Positives = 157/262 (59%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSP-KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
            L+GSHV  K K  L+GS  E  +Y  N FM++TG PQN  RK ++   I  A   M          IVVHAPY++NLG+  K +     ++ L  E+ R   + +K IVLHPG+ + +    AI  IA  L+  + A ++ V I +ETMAGKG+EVG +FEE++ I+    +  ++ VC DTCH  D+G  I +D D  L EF   + L  +KV+HLNDSKN  GS KDRH NIG G +GFD L   AH+ +L  VPKI+ETP
  S:     4 FLIGSHVSMKGKEMLLGSAQEAAQYGENVFMIYTGAPQNTRRKSIEGLNIPAAKTFMAAHEQ---REIVVHAPYVVNLGNTVKPANFQFAISFLTAEVQRAAALGAKQIVLHPGAHVGAGAPAAIAQIAQGLDTILTAAESPVQIALETMAGKGTEVGRSFEELAAIIDAPPHNDQLSVCFDTCHTSDAGYAIATDFDGVLNEFDHVIGLDRLKVVHLNDSKNPQGSHKDRHTNIGLGTLGFDVLNAVAHHPQLTTVPKIMETP 264
>gi|85057597|ref|YP_456513.1| endonuclease IV [Aster yellows witches'-broom phytoplasma AYWB] >gi|123518271|sp|Q2NJF9|END4_AYWBP Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|84789702|gb|ABC65434.1| endonuclease IV [Aster yellows witches'-broom phytoplasma AYWB] (292 aa)
Score = 524, Expect = 2.1e-51, Identities = 115/282 (40%), Positives = 176/282 (62%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN-DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP-DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEW 309
           L LGSHV  K  +   GS+   + Y  N  MV++G PQN +R + ++  I EA+K+ +  N L L N+V HAPY+INL +P ++ R+  ++ L  E+ R   +    +VLHPG+ L ++    I+ IA +L+     T +    I +ETMAGKG+E+G   EE+ +I + VKNK R+  CLDTCH+ D+G D+ +  ++ +++    L    + VIH+NDSKNE  S KDRH+NIG+GK+GF+ L+K  ++     +PKILETPY ++K  YK EI  + +K +
  S:     2 LFLGSHVAMKKPHNFQGSIQTAISYGANALMVYSGAPQNTIRSKTEELKIKEALKIAQNNN-LSLNNLVGHAPYIINLANPDKTKRAFAIDFLSQELERFAAMKINKMVLHPGNYLKTNPQEGISLIAQSLDLIFAKTKHLKTQISLETMAGKGTEIGKRLEELQQIRTLVKNKTRVSFCLDTCHLFDAGYDLKENLEEIIQKIDSILGFQNVSVIHINDSKNECNSHKDRHENIGFGKIGFETLLKIIYHRAFVCIPKILETPYINEKEPYKHEIEMIKTKNF 284
>gi|167935667|ref|ZP_02522742.1| endonuclease IV [Bacillus cereus AH1134] (288 aa)
Score = 523, Expect = 2.5e-51, Identities = 111/253 (43%), Positives = 164/253 (64%)
  Q:    38 AKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
            K  L+ +  E + Y    FM++TG PQN  RK +++  I+   K M+      +E I+VHAPY+IN+G + K  T  LG++ L +EI RT+ +  +K IVLHPG+ + +  +  I  I   LN+ +   +  V I +ETMAGKG+E G +FEE++KI+ GVK  +++ VC DTCH HD+G DI +D D  L EF K + +  ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L +VPKILETPY
  S:     2 GKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMELNG---IEEIIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVL-TPEQTVNIALETMAGKGTECGRSFEEIAKIIDGVKYNEKLSVCFDTCHTHDAGYDIVNDFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLMHVPKILETPY 253
>gi|47459383|ref|YP_016245.1| endonuclease IV [Mycoplasma mobile 163K] >gi|59797764|sp|Q6KH96|END4_MYCMO Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|47458713|gb|AAT28034.1| endonuclease IV [Mycoplasma mobile 163K] (279 aa)
Score = 515, Expect = 1.9e-50, Identities = 112/279 (40%), Positives = 174/279 (62%)
  Q:    23 MSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           M +NK+++GSHV FKA +YL G+   +     N  M++ G PQN  R  + +  I+E  +  ++   ++ ENI+VHAPY+ N  +P +       + LI EI R +   +K +VLHPG+     + +A   +   L K ++ T+N V+I +ETM+GKG+E+G    E++ ++  +K+  R+ +CLDTCH+ D+G DI + +  +    +   L YIKVIHLNDSKN+I S+KDRH+NIG G +GF+ L K   +EK  N+P ILETP+ ++ PIY +EI
  S:     1 MKENKIIIGSHVEFKAPDYLFGAAKTSYNNKANAMMIYLGAPQNSKRVNVSKYKIEEYKRDFEKI--IVPENIIVHAPYITNCANPDKF--DFATDFLIEEIRRMSFFGAKYLVLHPGAFTTFSKEIAYEILEKALIKILDQTEN-VVIALETMSGKGTEIGTKINELTNLIEKIKSP-RLALCLDTCHVWDAGYDIKNLEVFINHLEEIDALKYIKVIHLNDSKNDIFSKKDRHENIGKGFIGFETLQKIVFHEKFKNIPIILETPWVENIPIYDKEI 273
>gi|168334309|ref|ZP_02692496.1| endonuclease IV [Epulopiscium sp. 'N.t. morphotype B'] (284 aa)
Score = 514, Expect = 2.6e-50, Identities = 115/274 (41%), Positives = 169/274 (61%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGY--------GKVGFDYLVKWAHNEKLANVPKILETPYRD-DKPIYKQEI 301
           L +GSHV     N L+G+  E   Y  N FM++TG PQN  R  +++  I E  + MK      + +IVVHAPY+INL + KE T +     L +E+ RT  + S+ +V+HPG+   +  +  I+ I   +N A++  ++   + +ETM+GKG+E+G NF E+ +I++GV  K +IGVC DTCH+HDSG DI  D D  L+EF + +   YIKV+HLN S N  G++KDRH N+G          K+G   + K   N    N+P ILETP+ D +  +YK+EI
  S:     2 LKIGSHVSMS--NGLIGAAEEAWSYGANTFMIYTGAPQNTRRSPIEKLKIKEGQEFMKAHG---ISDIVVHAPYIINLAAAKEDTYAFAKEFLKLELARTKTLGSEYLVIHPGAYTSATLDEGIDRIVAAINSALQ--EDGPTLLLETMSGKGTEIGKNFHEIKRIIAGVIIKNKIGVCFDTCHLHDSGYDIVEDFDGVLKEFDELVGKDYIKVVHLNGSINVRGAKKDRHANLGADRTNPRGEDKIGITAIKKIVANPICQNIPLILETPWLDKNTNLYKEEI 278
>gi|191638512|ref|YP_001987678.1| Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) [Lactobacillus casei] >gi|190712814|emb|CAQ66820.1| Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) [Lactobacillus casei BL23] (287 aa)
Score = 513, Expect = 3.9e-50, Identities = 110/274 (40%), Positives = 165/274 (60%)
  Q:    37 KAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTR-SLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWK 310
           K    L+G+V E   Y  N    +TG PQN  RK   + +I E +  M +     + + V+HAPY++NLG+ K+S   +  +  +  E+ R + +H+  +  HPG+ + +    AI  I   LN+ I+  +  V I +ETMAGKG+E+G +F+E++ I+ GV + +++ V  DTCH +D+G DI +D D  L EF   + L  + VIH+NDSKN  GS KDRH NIG+G +GFD L K AH+  LA +PKILETPY     +   P Y  EI  L + +++
  S:     2 KGSEMLLGAVEEAASYTANTLQFYTGAPQNTRRKPTSEMMIPEGLAAMTKDG---ISHTVIHAPYIVNLGNTKKSENFTFAVQFMREEVARADALHAYTMPFHPGAHVGAGPEAAIKQIIKGLNEIIDP-NQKVTIALETMAGKGTEIGRSFDELAAIIDGVTHNEKLRVTFDTCHTNDAGYDIKNDFDGVLNEFDHIIGLDRLSVIHVNDSKNPQGSHKDRHANIGFGTIGFDALNKIAHHPALAELPKILETPYVGPDKKHQVPPYGAEIKWLKTGDFQ 278
>gi|15829092|ref|NP_326452.1| endonuclease IV [Mycoplasma pulmonis UAB CTIP] >gi|26006732|sp|Q98PU8|END4_MYCPU Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|14090036|emb|CAC13794.1| ENDONUCLEASE IV (ENDODEOXYRIBONUCLEASE IV) [Mycoplasma pulmonis] (277 aa)
Score = 509, Expect = 1.1e-49, Identities = 119/278 (42%), Positives = 174/278 (62%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEAT-DNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
           LGSHV FK+ NYL  S+ E+++   NC M+F G PQN  R + ++   ++ +K     N +  E+IVVHAPY+IN  S +++     ++ L  EI R ++   K +VLHPG    ++   +++ +A ++ K  E T D++V I +ETM+GKGSEVG ++EE+  ++  VK+  R+G CLDTCH+ D+G +I+D     +E  K   L +IKVIHLNDSKNE+GS KDRH NI  G +G   L +  H+    N+P ILETP+ +  PIY QEI  L  K
  S:     4 LGSHVSFKSPNYLYDSIKESIKNGANCAMIFLGAPQNTKRVDFEKYQYEKYLKDFS--NLIKPEDIVVHAPYIINPASLEKA--DFAISFLSSEIKRMDKAKFKYLVLHPGFYGKNNVKDSLDQLARSIQKIFEITKDSNVEIMLETMSGKGSEVGKSYEEILYVIDKVKSP-RLGACLDTCHVWDAGYNINDYQVFKDELIKTGILKHIKVIHLNDSKNELGSHKDRHANIDKGLIGLKNLKRIVHDPIFENIPIILETPWTEKGPIYDQEIAMLLEK 277
>gi|116495006|ref|YP_806740.1| endonuclease IV [Lactobacillus casei ATCC 334] >gi|116105156|gb|ABJ70298.1| Endonuclease IV [Lactobacillus casei ATCC 334] (287 aa)
Score = 506, Expect = 2.4e-49, Identities = 109/274 (39%), Positives = 163/274 (59%)
  Q:    37 KAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTR-SLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEWK 310
           K    L+G+V E   Y  N    +TG PQN  RK   + +I E +  M E     + + V+HAPY++NLG+ K+    +  +  +  E+ R + +H+  +  HPG+ + +    AI  I   LN+ I+  +  V I +ETMAGKG+E+G +F+E++ I+ GV + +++ V  DTCH +D+G DI +D D  L  F   + L  + VIH+NDSKN  GS KDRH NIG+G +GFD L K AH+  LA +PKILETPY     +   P Y  EI  L + +++
  S:     2 KGSKMLLGAVEEAASYMANTLQFYTGAPQNTRRKPTSEMMIPEGLAAMTEDG---ISHTVIHAPYIVNLGNTKKPENFTFAVQFMREEVARADALHAYTMPFHPGAHVGAGPEAAIQQIIKGLNEIIDP-NQKVTIALETMAGKGTEIGRSFDELAAIIDGVTHNEKLRVTFDTCHTNDAGYDIKNDFDGVLNAFDHIIGLDRLSVIHVNDSKNPQGSHKDRHANIGFGTIGFDALNKIAHHPALAELPKILETPYVGPDKKHQVPPYGAEIKWLKTGDFQ 278
>gi|193216685|ref|YP_001999927.1| endonuclease IV [Mycoplasma arthritidis 158L3-1] >gi|193002008|gb|ACF07223.1| endonuclease IV [Mycoplasma arthritidis 158L3-1] (276 aa)
Score = 495, Expect = 4.1e-48, Identities = 119/278 (42%), Positives = 168/278 (60%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYL----DLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
           LGSHV FKA +YL G++ E+L+   NC M++ GPPQN  R  +++   ++   L K  + +  E+IVVHAPY++NL +   S +   ++ L+ E  R N I  K +VLHPG   +      A++ +   L K +E T  D+ IC+ETMAGKGSE+  NFE++  ++  V N  R+ +CLDTCH+ D+G +I D D     F KYL     L  IKVIHLNDS N+  S KDRH NI  G +  + L ++ H++   N+P ILETP   D   YK EI  L +K
  S:     4 LGSHVSFKAPDYLCGAIKESLDNGANCAMIYLGPPQNSTRISVEKYHYEDY--LAKYSSQIKAEDIVVHAPYIVNLAN--RSKQEFAIDFLVAECQRANYIGIKYLVLHPGFHNNLYPVKEALDILVFGLKKILEQT-KDITICLETMAGKGSEICSNFEDIKYVIDQVNND-RVAMCLDTCHIWDAGYNIKDYDA----FKKYLIDNDYLKLIKVIHLNDSLNDRASHKDRHANIDKGYIKLETLKRFVHDKDFDNIPIILETPRTKDWSPYKDEIKTLLAK 276
>gi|164687512|ref|ZP_02211540.1| hypothetical protein CLOBAR_01153 [Clostridium bartlettii DSM 16795] >gi|164603286|gb|EDQ96751.1| hypothetical protein CLOBAR_01153 [Clostridium bartlettii DSM 16795] (277 aa)
Score = 491, Expect = 1.3e-47, Identities = 111/260 (42%), Positives = 155/260 (59%)
  Q:    48 ETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
           E L  D N F  FT  P+    K+LDQN ID+ +KL KE N      ++ HAPY +N  +  ES R   +N  I ++ R     + L   HPGS +    +V I +I D LN+A+   +    + +ETMAGKG+EVG +FEE+  I+ GV+  +++GVCLDTCH+ D+G DI ++ D  LEEF   + L  +K IHLNDS N  GS KDRH  IG G++G D +V+  +++ L N+P +LETP   D   Y +EI  L SK
  S:    20 EALSIDANTFQFFTRNPRGGKAKQLDQNDIDKFLKLAKENN---FAQLLAHAPYTLNACAADESKREFAVNTFIDDLKRLELTPNNLYNFHPGSHVKQGVDVGIKYITDMLNQAL-TKEQTTTVLLETMAGKGTEVGRSFEELKAIIDGVEIDEKLGVCLDTCHVFDAGYDIVNNLDGVLEEFDNIIGLDRLKAIHLNDSLNSCGSHKDRHAKIGEGQIGLDAIVRIINHDALKNLPFLLETPNELDG--YAKEIELLKSK 274
>gi|42783410|ref|NP_980657.1| endonuclease IV [Bacillus cereus ATCC 10987] >gi|42739339|gb|AAS43265.1| endonuclease, putative [Bacillus cereus ATCC 10987] (250 aa)
Score = 464, Expect = 1.5e-44, Identities = 101/222 (45%), Positives = 145/222 (65%)
  Q:    69 RKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG-SPKESTRSLGLNQLIVEINRTNQIH-SKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           RK ++QN I+E               I+VHAPY+IN+G + K  T  LG++ L +EI RT+ +  +K IVLHPG+ + +  +  I  I   LN+ +   D  V I +ETMAGKG+E G +FEE++KI+ GVK  +++ VC DTCH HD+G DI +D D  L EF K + +  ++V+H+NDSKN  G+ KDRH+NIG+G +G+  L    H+ +L +VPKILETPY
  S:     7 RKHMEQNGIEE---------------IIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTSXLGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVL-TPDQTVNIALETMAGKGTECGRSFEEIAKIIDGVKYNEKLSVCFDTCHTHDAGYDIVNDFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLTHVPKILETPY 215
>gi|188588008|ref|YP_001920071.1| AP endonuclease, family 2 [Clostridium botulinum E3 str. Alaska E43] >gi|188498289|gb|ACD51425.1| AP endonuclease, family 2 [Clostridium botulinum E3 str. Alaska E43] (277 aa)
Score = 440, Expect = 1.1e-41, Identities = 103/257 (40%), Positives = 149/257 (57%)
  Q:    50 LEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           L+   N F  FT  P+    K++D+N + E ++L KE        I+ HAPY +N  S  E  R   +  +  ++ R   I + L   HPGS +     V I +I+  LN +I   D    + +ETM+GKG+EVG NFEE+++I+  V+ K+ +GVCLDTCH+HD+G DI ++ D+ LEEF   + L  +  IHLNDSKN   S KDRH+ IG G +G D L    ++ KL ++P  LETP  ++   YK+EI  L S
  S:    22 LKIGANTFQFFTRNPRGSKAKDIDENDVKEFLELAKENK---FCKILAHAPYTLNACSADERNREFAIEIMADDLKRMEYIPNNLYNFHPGSHVKQGTEVGIEYISSALN-SILKKDQTTKVLLETMSGKGTEVGRNFEEIAEIIKRVELKEHVGVCLDTCHIHDAGYDIVNELDEVLEEFDSMIGLDKLYAIHLNDSKNPFESHKDRHETIGNGYIGLDALTNIINHPKLCHLPFFLETP--NELEGYKREIELLKS 273
>gi|145955983|ref|ZP_01804983.1| hypothetical protein CdifQ_04000585 [Clostridium difficile QCD-32g58] >gi|168694942|ref|ZP_02727219.1| endonuclease IV [Clostridium difficile QCD-37x79] >gi|168726026|ref|ZP_02758303.1| endonuclease IV [Clostridium difficile QCD-76w55] >gi|168733340|ref|ZP_02765617.1| endonuclease IV [Clostridium difficile QCD-97b34] >gi|196162392|ref|ZP_03122953.1| endonuclease IV [Clostridium difficile CIP 107932] (278 aa)
Score = 433, Expect = 6.6e-41, Identities = 100/264 (37%), Positives = 152/264 (57%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDG-NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKN--PLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           LG+H+   AK +   +  ET  Y G N F  F+  P+    KE D+  I +  ++ KE N  PLL      HAPY +NLG  K+         +  +I R + +  + +  HPGS +    +  I+ I   LN AI+  D ++ I +ETM+GKG+E+G  FE++  I+  +++K++IGVCLDTCH+  +G DI +D D  LEEF K + +  +K +HLNDS    G +KDRH  IG GK+G   L+ +  +  L ++P  LETP+ D+
  S:     4 LGTHLSI-AKGF--ANAAETAVYIGANTFQFFSRNPRGGNAKEFDEKDIIKFQEIRKENNFAPLL-----AHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIEYMCFHPGSHIGGGVDFGIDRIVKGLNNAIKG-DENITILLETMSGKGTEIGFKFEQLKSIIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMPFGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDE 262
>gi|187933215|ref|YP_001884913.1| AP endonuclease, family 2 [Clostridium botulinum B str. Eklund 17B] >gi|187721368|gb|ACD22589.1| AP endonuclease, family 2 [Clostridium botulinum B str. Eklund 17B] (277 aa)
Score = 433, Expect = 7.1e-41, Identities = 101/257 (39%), Positives = 150/257 (58%)
  Q:    50 LEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           L+   N F  FT  P+    K++D+N + E ++L KE N      I+ HAPY +N  S  E  R   +  +  ++ R   + + L   HPGS +     V I +I+  LN +I   D    + +ETM+GKG+EVG NFEE+++I+  V+ K+ +GVCLDTCH+HD+G DI ++ D+ LEEF+  + L  +  IHLNDSKN   S KDRH+ IG G +G + +    ++ KL ++P  LETP  ++   YK EI  L S
  S:    22 LKIGANTFQFFTRNPRGSKAKDIDENDVKEFLELAKENN---FCKILAHAPYTLNACSADERNREFAIEIMADDLKRMEYLPNNLYNFHPGSHVKQGTEVGIEYISSALN-SILKKDQTTKVLLETMSGKGTEVGRNFEEIAEIIKRVELKEHVGVCLDTCHIHDAGYDIVNELDKVLEEFNSIIGLDKLDAIHLNDSKNPFESHKDRHETIGNGYIGLEAVTNIINHPKLCHLPFFLETP--NELEGYKNEIELLKS 273
>gi|126698139|ref|YP_001087036.1| endonuclease IV [Clostridium difficile 630] >gi|168715563|ref|ZP_02747840.1| endonuclease IV [Clostridium difficile QCD-63q42] >gi|196124327|ref|ZP_03116076.1| endonuclease IV [Clostridium difficile ATCC 43255] >gi|123066928|sp|Q189A4|END4_CLOD6 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|115249576|emb|CAJ67393.1| endonuclease IV [Clostridium difficile 630] (278 aa)
Score = 432, Expect = 7.9e-41, Identities = 100/264 (37%), Positives = 152/264 (57%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDG-NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKN--PLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           LG+H+   AK +   +  ET  Y G N F  F+  P+    KE D+  I +  ++ KE N  PLL      HAPY +NLG  K+         +  +I R + +  + +  HPGS +    +  I+ I   LN AI+  D ++ I +ETM+GKG+E+G  FE++  I+  +++K++IGVCLDTCH+  +G DI +D D  LEEF K + +  +K +HLNDS    G +KDRH  IG GK+G   L+ +  +  L ++P  LETP+ D+
  S:     4 LGTHLSI-AKGF--ANAAETAVYIGANTFQFFSRNPRGGNAKEFDEKDIIKFQEIRKENNFAPLL-----AHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIEYMCFHPGSHVGGGVDFGIDRIVKGLNNAIKG-DENITILLETMSGKGTEIGFKFEQLKSIIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMPFGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDE 262
>gi|68369976|ref|XP_686479.1| PREDICTED: similar to APurinic/apyrimidinic endoNuclease family member (apn-1) [Danio rerio] (296 aa)
Score = 431, Expect = 1.2e-40, Identities = 98/269 (36%), Positives = 153/269 (56%)
  Q:    23 MSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEK-----NPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR 291
           M   K  +G+HV      +   +V  ++   G+ F +F G  +++ R  LD      AVK  +       +P+   +I+ H  YL+N GSPKE   S     L+ E++R + +       HPG+A+DS     +  IA  +N A + T   VI  +E M+G+GS +G  F E+  I+  V++K R+GVCLDTCH   +G DIS P   +  L+EF + + L Y++ +HLNDSK ++GS  DRH++IG+G++G     +  +  +L N+P ILETP R
  S:     7 MKPQKKYIGAHVSISGGIW--KAVESSVAMGGHAFALFLGSQRSWTRPVLDSK---AAVKFQQACAEHGFDPV---HILPHGSYLMNCGSPKEDVFSKSQAMLVDELSRCDALGLSQFNFHPGAAMDSSPEKCMEKIAQAINHAHQQTPA-VITVLENMSGQGSTIGGQFSELKGIIDRVRDKSRVGVCLDTCHAFAAGYDISPPGGVNNMLDEFDRVVGLHYLRAVHLNDSKGKLGSHLDRHEDIGHGQIGITAFREIVNEPRLDNIPLILETPGR 274
>gi|160933968|ref|ZP_02081355.1| hypothetical protein CLOLEP_02830 [Clostridium leptum DSM 753] >gi|156866641|gb|EDO60013.1| hypothetical protein CLOLEP_02830 [Clostridium leptum DSM 753] (271 aa)
Score = 428, Expect = 2.8e-40, Identities = 101/260 (38%), Positives = 144/260 (55%)
  Q:    47 LETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP-DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           L  ++   N    FT  P+    KELDQ  I     LM E +      I+ HAPY +N  S    TR   L  L  ++ R   +       HPGS +       I+ I+D LN+ I   +   I+ +ETMAGKGSE+G +F+E+ +I+ GV+ ++++G+CLDTCH+ D G DI+   DQ LEEF   + LS +K +HLNDS N +GS KDRH NIG G +G +   +  ++  L ++P  LETP  DD   + +EI  L S
  S:    12 LTAVKIGANTLQFFTRNPRGSKAKELDQKDIAAFRLLMNEHH---FGKILAHAPYTLNPASSNGHTREFALETLRDDLIRMESLPGNYYNFHPGSHVGGGVQTGIDLISDALNQ-ILFPNQSTIVLLETMAGKGSEIGGSFQELRRIIDGVELQEKLGICLDTCHVSDGGYDIAGRLDQVLEEFDHVIGLSRLKAVHLNDSLNPLGSHKDRHANIGKGTLGLEAFERMINHPVLRDLPFYLETPNDDDG--HGEEIALLKS 266
>gi|158319388|ref|YP_001511895.1| apurinic endonuclease Apn1 [Alkaliphilus oremlandii OhILAs] >gi|166920081|sp|A8ML82|END4_ALKOO Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|158139587|gb|ABW17899.1| apurinic endonuclease Apn1 [Alkaliphilus oremlandii OhILAs] (281 aa)
Score = 425, Expect = 6.2e-40, Identities = 94/260 (36%), Positives = 146/260 (56%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           L S  G+KA         + +  + N F  FT  P+    K +D   ++  ++LM+E        I+ HAPY +N  S  E TR   +  L+ ++ R   + +     HPG+ L     V I +I ++LN  ++  D    + +ETM+GKG+E+G NFEE+ +I+ G+K   ++GVCLDTCH++D+G DI  D D  ++EF + + L  +  IHLNDSKN   S KDRH  IG G +G + +V+  ++ KL ++P  LETP
  S:     8 LSSSKGYKAMGK------DAISINANTFQFFTRNPRGSKAKAMDLKDVEGLLQLMEENK---FAKILAHAPYTLNPCSADERTREFAMEVLVDDLARMEYLPNNFYNFHPGNHLKQGVEVGIEYIVNSLNDVLKP-DQTTTVLLETMSGKGTEIGKNFEELKQIIDGIKLSNKVGVCLDTCHVYDAGYDIVQDLDGVIQEFDRIIGLDKLYAIHLNDSKNPFASHKDRHAKIGEGYIGEEGIVRIINHPKLRHLPFFLETP 258
>gi|84489791|ref|YP_448023.1| putative endonuclease IV [Methanosphaera stadtmanae DSM 3091] >gi|121721580|sp|Q2NFM3|END4_METST Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|84373110|gb|ABC57380.1| putative endonuclease IV [Methanosphaera stadtmanae DSM 3091] (276 aa)
Score = 424, Expect = 7.1e-40, Identities = 99/255 (38%), Positives = 146/255 (57%)
  Q:    47 LETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           LE L  D N    F   P+    K L+Q  +D   +LM       ++ I+ HAPY+INL S  E TR+        ++ R + + + +   HPGS +       I  I+D+LNK I   D    I +ETMAGKG+E+G  FEE+  I+  +   +++GVC+DTCH++D G DI +D D  ++EF   + L  +K IHLNDSK  + S KDRH+ IG GK+G D + +  +++KL ++P  LETP  +D   YK+EI
  S:    19 LEALSIDANTAQFFPRSPRGGKAKPLNQADVDGLQELMDNTT---MDVILAHAPYIINLASKSEKTRNNAYEIFEDDLKRLDNLPNNMYNFHPGSHVQQGVEKGIELISDSLNKLIRE-DMKTTILLETMAGKGTEIGRTFEELESIIEKIDMDEKVGVCIDTCHIYDGGYDIVNDLDGVIDEFDSIIGLDRLKAIHLNDSKYGLNSHKDRHEKIGMGKIGIDAITEIINHKKLRDLPFYLETP--NDVEGYKEEI 268
>gi|150015441|ref|YP_001307695.1| apurinic endonuclease Apn1 [Clostridium beijerinckii NCIMB 8052] >gi|189037122|sp|A6LQV9|END4_CLOB8 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|149901906|gb|ABR32739.1| apurinic endonuclease Apn1 [Clostridium beijerinckii NCIMB 8052] (277 aa)
Score = 424, Expect = 7.3e-40, Identities = 98/259 (37%), Positives = 148/259 (57%)
  Q:    48 ETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           E +   GN F  FT  P+    K +D+  I E +KL +E N      I+ HAPY +N  S  E+TR+  +  +  ++ R   I + L   HPGS +     + I +I+D LN  ++      ++ +ETMAGKG+E+G  F+E+ +I++ V+   ++GVCLDTCH+HD+G DI ++ D+ +E+F K + L  +  IHLNDS N  GS KDRH  IG G +G + +    ++  L N+P  LETP   D   Y +EI  L S
  S:    20 EAISIGGNTFQFFTRNPRGSKAKTIDETDIKEFLKLAEENN---FSKILGHAPYTLNACSADENTRNFAVEIMKDDLERMEYIPNNLYNFHPGSHVKQGVEIGIKYISDMLNTVLKPEQTTTVL-LETMAGKGTEIGRTFDELKEILNNVELSHKVGVCLDTCHVHDAGYDIVNNLDKVVEQFDKIIGLDKLCAIHLNDSMNPFGSHKDRHQKIGEGSIGLEGIKNIINHPMLCNLPFFLETPNELDG--YAREIKLLKS 273
>gi|196164766|ref|ZP_03125297.1| endonuclease IV [Clostridium difficile QCD-23m63] (278 aa)
Score = 422, Expect = 1.3e-39, Identities = 98/264 (37%), Positives = 151/264 (57%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDG-NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKN--PLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           LG+H+   AK +   +  ET  Y G N F  F+  P+    KE ++  I +  ++ K  N  PLL      HAPY +NLG  K+         +  +I R + +  + +  HPGS +    +  I+ I   LN AI+  D ++ I +ETM+GKG+E+G  FE++  I+  +++K++IGVCLDTCH+  +G DI +D D  LEEF K + +  +K +HLNDS    G +KDRH  IG GK+G   L+ +  +  L ++P  LETP+ D+
  S:     4 LGTHLSI-AKGF--ANAAETAVYIGANTFQFFSRNPRGGNAKEFNEKDIIKFQEIRKANNFAPLL-----AHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIEYMCFHPGSHVGGGVDFGIDRIVKGLNNAIKG-DENITILLETMSGKGTEIGFKFEQLKSIIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIDRLKTVHLNDSMMPFGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDE 262
>gi|68479847|ref|XP_716092.1| hypothetical protein CaO19.7428 [Candida albicans SC5314] >gi|46437744|gb|EAK97085.1| hypothetical protein CaO19.7428 [Candida albicans SC5314] (336 aa)
Score = 417, Expect = 4.8e-39, Identities = 91/267 (34%), Positives = 153/267 (57%)
  Q:    45 SVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQT---LEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +VL  ++   N F +F   P+ ++  ++ +  I +  +L ++       +I+ H  Y INLG+P            + ++ R  +++  +   HPGS+LD D   ++  +A N+NKAIE T+  V I +E MAG G+ +G N +++  ++  V+ K R+GVCLDTCH   +G DISD ++    L++F + +   Y+  IHLNDSK  +G+ +D H  +GYG +G +     A++++L N+P ILETP  +D  +Y +EI  L   EW E
  S:     8 AVLNAMDIGANSFALFLKSPRKWVSPDIKEEEIKKFHELCEKYGYNSRTDILPHGSYFINLGNPDPEKEEKAYGSFLDDLKRCEKLNIGMYNFHPGSSLDGDHKESLARLAKNINKAIEETEF-VKIVIENMAGHGNLIGSNLQDIKDVIDMVEEKSRVGVCLDTCHSFAAGYDISDKEKFEDFLKQFDEIIGAEYLSAIHLNDSKAPLGANRDLHQKLGYGFLGLEVFRVIANSDRLKNIPIILETPVGNDDSVYGEEIKLL---EWLE 273
>gi|167773038|ref|ZP_02445091.1| hypothetical protein ANACOL_04427 [Anaerotruncus colihominis DSM 17241] >gi|167664971|gb|EDS09101.1| hypothetical protein ANACOL_04427 [Anaerotruncus colihominis DSM 17241] (286 aa)
Score = 415, Expect = 8.0e-39, Identities = 105/281 (37%), Positives = 147/281 (52%)
  Q:    21 MCMSKNKLLLGSHVGFKAKNYL-VGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           M + +  + +G H+   AK Y  +G   + L    N F  FT  P+    K LD + +   ++LM   N      IV HAPY +N  S     R L  + +  ++ R   +   L   HPGS         I  IAD LN  +    +  ++ +ETMAGKGSEVG  FEE+  I+  V   +R+GVCLDTCH+ D+G DI +D D  L EF + + LS +  +HLNDS N  GSRKDRH  +G G +G + LV+   +  L  +P  LETP  ++ P Y  EI
  S:     1 MMIRRMFMYIGCHLS-AAKGYAHMGK--DALSIGANTFQFFTRNPRGARAKALDPDDMRALLELM---NANAFGTIVAHAPYTLNACSSDPHLRELARDMIADDLERMEHLPGNLYNFHPGSHTGQGVETGIAQIADMLNSVLRPGLHTTVL-LETMAGKGSEVGGRFEELRAILDRVAISERMGVCLDTCHVSDAGYDIVNDLDGVLTEFDRVIGLSRLHAVHLNDSMNPRGSRKDRHARLGEGTIGVEALVRVVRHPALKGLPICLETP--NELPGYAAEI 274
>gi|153855572|ref|ZP_01996688.1| hypothetical protein DORLON_02706 [Dorea longicatena DSM 13814] >gi|149751993|gb|EDM61924.1| hypothetical protein DORLON_02706 [Dorea longicatena DSM 13814] (298 aa)
Score = 414, Expect = 1.2e-38, Identities = 97/275 (35%), Positives = 152/275 (55%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLE----YDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           +G+H+       + G + +T E     + N   +F+  P+    K   Q   +E  K  + +       ++ HAPY +NL S  E T       +  +I R +++  + +V HPGS         I +I   L++AI  T+N + + +ETM+GKG+E+G  FE++ +I  GV++ +RIG+CLDTCH+  +G DI  D D  L+EF + L L  ++ IHLNDS    GSRKDRH  IG G++G + L+    + KL ++P  LETP  D    +K+EI  L
  S:    24 IGTHMS------IAGGIAKTAENVVKMNANTMQIFSRNPRGSSYKTYAQ---EEVEKFQQIRKSHAFGPVLAHAPYTMNLASATEKTYEFACTVIREDIRRMDELKIENLVFHPGSHTGIGEEAGITNIIRGLDQAITGTEN-IKVLLETMSGKGTEIGYRFEQLKQIRDGVQHPERIGICLDTCHVFAAGYDIVHDLDGVLDEFDRILGLELLRTIHLNDSLMPFGSRKDRHAVIGEGEIGLEALLNVLRHPKLKDLPFYLETPLDDAG--HKEEIARL 291
>gi|153810761|ref|ZP_01963429.1| hypothetical protein RUMOBE_01145 [Ruminococcus obeum ATCC 29174] >gi|149833157|gb|EDM88239.1| hypothetical protein RUMOBE_01145 [Ruminococcus obeum ATCC 29174] (279 aa)
Score = 414, Expect = 1.2e-38, Identities = 97/265 (36%), Positives = 140/265 (52%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRD 292
           L +G+H    +K Y      + ++  GN F  FT  P+    K +D+  I   + L +E +      IV HAPY +N  + KE  R+        ++ R           HPGS +     + I  IA+ LN  +   +    + +ETM+GKG+EVG NFEE+ KI++ V+ K ++G+CLDTCH+ D G DI  D D  L +F   + L  +K IHLNDS N+ GS KDRH  IG GK+G + L +   +  L  +P ILETP  D
  S:     4 LYIGNHTS-SSKGY-AAMARQIIKNGGNTFAFFTRNPRGGKAKAIDETDIQNFLVLAQENH---FGKIVAHAPYTLNACAAKEELRTFARETFADDLRRMEYTPGNYYNFHPGSHVGQGSEIGIQKIAEILNDVL-TEEQTTTVLLETMSGKGTEVGRNFEELRKILNLVEKKSKMGICLDTCHVWDGGYDIVHDLDGVLNDFDHIIGLERLKAIHLNDSLNDCGSHKDRHARIGEGKIGMEALARIIKHPALREIPFILETPNDD 263
>gi|169334687|ref|ZP_02861880.1| hypothetical protein ANASTE_01090 [Anaerofustis stercorihominis DSM 17244] >gi|169257425|gb|EDS71391.1| hypothetical protein ANASTE_01090 [Anaerofustis stercorihominis DSM 17244] (277 aa)
Score = 412, Expect = 1.7e-38, Identities = 102/274 (37%), Positives = 155/274 (56%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           L +G+H+   AK Y      + L    N F  FT  P+    K+L +  ID   K+M+E N     +I+ HAPY +N+ S K+ TR         +++  NQI S L   HPGS         I+ I + LN+ I+  D+D  I +ETM+GKGSE+G  FEE+ +I+  VK K ++GVC+DTCH+  +G DI +D D  L +F K + L  +K +HLND+ N+  + KDRH  IG G +  + L+ + ++  + ++P  LETP  ++   YK+EI
  S:     2 LNIGAHMSI-AKGYEAAGK-DALSIGANTFQFFTRNPRGGKAKDLSEKDIDRLRKIMEENN---FSDILAHAPYTLNMASAKKDTREFAKELFRKDLDIMNQIPSHLYNFHPGSHTTDSIEEGISRIQETLNECIKE-DDDTFILLETMSGKGSEIGKTFEELREILDRVKLKDKMGVCIDTCHVFCAGYDIVNDLDGVLTKFDKVIGLDKLKAVHLNDTMNDFNTNKDRHAKIGEGFLKTEPLINFINHPAIKDLPIFLETP--NELEGYKKEI 268
>gi|167761857|ref|ZP_02433984.1| hypothetical protein BACSTE_00200 [Bacteroides stercoris ATCC 43183] >gi|167700227|gb|EDS16806.1| hypothetical protein BACSTE_00200 [Bacteroides stercoris ATCC 43183] (277 aa)
Score = 410, Expect = 3.0e-38, Identities = 94/255 (36%), Positives = 148/255 (58%)
  Q:    54 GNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKE---KNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
            N F +FT   + ++ K L Q    E++ L KE   K  L    I+ H  YLINLG P+E          + E+ R  ++  +L+  HPGS L+       ++ +A+++N  +  T   V   +E  AG+GS VG  F ++  I+  V++K R+GVCLDTCH + +G DI ++ D+  +EF K +   +++ IHLNDSK  +GSR DRHD+IG G +G D+  ++  +E+  ++P ILETP   D+ ++ +EI  L S E
  S:    26 ANAFALFTKNQRQWVAKPLTQ----ESIALFKENCRKYALEARYILPHDSYLINLGHPEEEGLEKSRAAFLDEMRRCEELGLELLNFHPGSHLNKISVEACLDRVAESINITLGKTQG-VTAVIENTAGQGSNVGNEFWQLKHIIDRVEDKSRVGVCLDTCHTYTAGYDIVNEYDKVFDEFDKTVGFGFLRAIHLNDSKKALGSRVDRHDSIGKGLIGLDFFKRFMKDERFNDMPVILETP---DETLWAEEISMLRSFE 277
>gi|150021280|ref|YP_001306634.1| apurinic endonuclease Apn1 [Thermosipho melanesiensis BI429] >gi|166224293|sp|A6LMU8|END4_THEM4 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|149793801|gb|ABR31249.1| apurinic endonuclease Apn1 [Thermosipho melanesiensis BI429] (283 aa)
Score = 406, Expect = 8.6e-38, Identities = 100/254 (39%), Positives = 146/254 (57%)
  Q:    48 ETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           ET E  GN F +F   P+ +  K    + ++   K +KE N L  ++++ H+ YLIN+ SPKE      L  LI+E+N    +  + + +HPGS L+S     IN I   LN A+E  + +  I +E +  KG  +G   EE+  I+  VK  +RIG+ +DTCH  D+G DI++    D+ L+   K   L  +K IHLNDSKNE+GS KDRH+NIG GK+G   L  +  NE +  +P ILETP   D  ++K +I
  S:    20 ETHEIGGNAFQIFPHNPRQWKAKLPKDDDVEIFKKRVKEYN-LTEDSMLCHSGYLINIASPKEEIWQKSLELLILEMNICKTLGIRYLNIHPGSHLNSGVEKGINQIVKALNIAME-KEKETFILLENVTKKGGNIGSTLEELKMIIEMVKYPERIGITIDTCHAFDAGYDITNKEKLDKFLKMIDKLFSLEKLKFIHLNDSKNELGSNKDRHENIGKGKIGVKGLKTFLTNETIQKIPWILETP--GDNEVHKNDI 272
>gi|15616757|ref|NP_239969.1| endonuclease IV [Buchnera aphidicola str. APS (Acyrthosiphon pisum)] >gi|11132254|sp|P57237|END4_BUCAI Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|25289184|pir||G84945 deoxyribonuclease IV (phage-T4-induced) (EC 3.1.21.2) [imported] - Buchnera sp. (strain APS) >gi|10038820|dbj|BAB12855.1| endonuclease IV [Buchnera aphidicola str. APS (Acyrthosiphon pisum)] (281 aa)
Score = 405, Expect = 1.2e-37, Identities = 102/279 (36%), Positives = 161/279 (57%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   +   L  +VL  ++     F  FT   + +    L Q  ID+  K M  K     + I+ H+ YLINLG P +          I E+ R +Q+    +  HPGS L+    N  +  ++D++N A+E T N VI  +E  AG+G+ +G  FE +S+I+  + +K R+GVC+DTCH+  SG D+    D + T E+F+  + L Y+K IHLNDSK +I SR DRH+++G G++G   F +++K   NE  +N+P ILET    +  I+++EI  L S++
  S:     4 IGAHV--SSSGGLEKTVLRAIQIKATAFSFFTKNQRQWFSPPLIQKKIDQ-FKAMCIKYSFQPQQILPHSSYLINLGHPIDELLRKSRKSFIDEMIRCSQLGLIFLNFHPGSHLNKITENACLLRVSDSINIALEKTQN-VIAVIENTAGQGTNIGYCFEHLSEIIKNIDDKSRVGVCIDTCHLFASGYDLRTKKDCENTFEKFNSLIGLKYLKGIHLNDSKKKINSRVDRHESLGLGEIGTAAFTWIIK---NENFSNIPIILETA---NPMIWEEEIDWLRSQK 279
>gi|160888878|ref|ZP_02069881.1| hypothetical protein BACUNI_01298 [Bacteroides uniformis ATCC 8492] >gi|156861777|gb|EDO55208.1| hypothetical protein BACUNI_01298 [Bacteroides uniformis ATCC 8492] (280 aa)
Score = 404, Expect = 1.4e-37, Identities = 98/278 (35%), Positives = 156/278 (56%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLL---LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
            +G+HV   A   +  + +   E   N F +FT       R+ + + L +E++++ KE    L      I+ H  YLINLG P+E          + E+ R  Q+  KL+  HPGS L+       ++ +A+++N  +  T +DV+  +E  AG+GS VG  F ++  I+  V +K R+GVCLDTCH + +G DI ++ D+  EEF   +   Y++ IHLNDSK  +GSR DRHD+IG G +G D+  ++  + +   +P ILETP   D+ ++ +EI  L S
  S:     3 FIGAHV--SASGGVEAAPVNASEIGANAFALFT----KNQRQWVARPLTEESIRVFKENCGKLGFDSRYILPHDSYLINLGHPEEEGLQKSRAAFLDEMQRCEQLGLKLLNFHPGSHLNKISVEECLDKVAESINLILGKT-HDVVAVIENTAGQGSNVGNEFWQLGHIIDRVDDKSRVGVCLDTCHTYTAGYDIVNEYDKVFEEFDAAVGFGYLRGIHLNDSKKALGSRVDRHDSIGKGLIGMDFFRRFMQDVRFDGIPIILETP---DESLWAEEIKLLRS 275
>gi|160894667|ref|ZP_02075442.1| hypothetical protein CLOL250_02218 [Clostridium sp. L2-50] >gi|156863601|gb|EDO57032.1| hypothetical protein CLOL250_02218 [Clostridium sp. L2-50] (280 aa)
Score = 403, Expect = 2.0e-37, Identities = 105/277 (37%), Positives = 143/277 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID-ISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           L S  GF+A    +G     L+   N F  FT  P+    KE+D         LM+E +      +V HAPY +N+ + K   R    N L  ++ R   +       HPG+ +      AI  IAD LN AI+  D   ++ +ETMAGKGSEVG NFEE+ +I+  V  + +IGVC DTCH  D G D + D D  L  F + + L  +K +HLNDS N   S KDRH  IG G++G + L +   +  LA  P ILETP  +D   Y +EI  + S
  S:     8 LSSSKGFEA----MGKA--ALKLGANTFAFFTRNPRGGKAKEIDPADAKRLRSLMEEHH---FGKLVAHAPYTMNVCAAKPDIREFSCNILKDDMERMEYLPGNYYNFHPGAHVGQGAEEAIPVIADALNHAIKP-DQSTVVLLETMAGKGSEVGRNFEELERIIELVDCEDKIGVCFDTCHTWDGGYDLVEDLDGVLHTFDQIIGLDRLKAVHLNDSMNVRDSHKDRHQKIGEGEIGAEALKRIVTHPLLAGRPFILETP--NDDAGYAREIAMIKS 273
>gi|84393247|ref|ZP_00992009.1| endonuclease IV [Vibrio splendidus 12B01] >gi|84376153|gb|EAP93039.1| endonuclease IV [Vibrio splendidus 12B01] (302 aa)
Score = 402, Expect = 2.6e-37, Identities = 98/279 (35%), Positives = 153/279 (54%)
  Q:    26 NKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           N   +G+HV   A   +  + +   E   N F +FT   + +  K L+   I  A K   +      ENI+ H  YLINLG+P+E          I E+ R NQ+   L+  HPGS L  +  +  +  IA+++N A +A   DVI  +E  +G+G+ +G  FE +++I+  V++K R+GVCLDTCH   +G D+   +   QT  EF + + + Y++ +H+NDSK E  SR DRH ++G G++G+D     A + +   +P ILET    D  I+K+EI  L
  S:    13 NIKFIGAHV--SAAGGVDQAPMRAREIGANAFALFTKNQRQWAAKPLEAKTI-SAFKANCKMLGFSAENILPHDSYLINLGAPEEEKLEKSRAAFIDEMERCNQLGLTLLNFHPGSHLKKTSESECLAKIAESINLAHQAVP-DVIAVIENTSGQGTNLGWRFEHLAEIIDQVEDKSRVGVCLDTCHTFTAGYDLRTKEACEQTFAEFERIVGMHYLRAMHINDSKAEFASRVDRHHSLGKGEIGWDCFEYIASDSRFNGIPLILETI---DSTIWKEEIQQL 288
>gi|20799559|gb|AAM28547.1|AF494517_2 putative endonuclease IV [Tomato big bud phytoplasma] (208 aa)
Score = 400, Expect = 4.6e-37, Identities = 85/203 (41%), Positives = 134/203 (66%)
  Q:    52 YDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN-DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP-DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRK 254
           ++ N FM+++GPPQ+  R  ++++ I + +  MK  N + +  +V HAPY+INL +P    R   +N L  E+NR +Q+    +VLHPG+ L  +++ AI  IA  +NK    T N    I +ETMAGKG+E+G NFEE+  I+  +++K RI +C DTCH+ D+G DI +  + T+++F K ++L Y+ VIH+NDSKN +GS+K
  S:     2 FNSNTFMLYSGPPQSTQRNIIEKDDIHKTLLKMKNHN-ININFLVGHAPYIINLANPSLEKREFSINFLTQELNRFSQMKIPQMVLHPGNNLHKNKSEAIYWIAQGINKIFSNTPNLKTKIALETMAGKGNEIGANFEELKNIIDLIEDKTRISICFDTCHVFDAGYDIKNQFENTIKKFDKIINLKYLSVIHINDSKNCLGSKK 205
>gi|165975817|ref|YP_001651410.1| endonuclease IV [Actinobacillus pleuropneumoniae serovar 3 str. JL03] >gi|190149649|ref|YP_001968174.1| putative endonuclease 4 [Actinobacillus pleuropneumoniae serovar 7 str. AP76] >gi|165875918|gb|ABY68966.1| endonuclease IV [Actinobacillus pleuropneumoniae serovar 3 str. JL03] >gi|189914780|gb|ACE61032.1| putative endonuclease 4 [Actinobacillus pleuropneumoniae serovar 7 str. AP76] (280 aa)
Score = 399, Expect = 6.2e-37, Identities = 92/259 (35%), Positives = 146/259 (56%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDIS---DPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILET 288
           +G+HV   A   +  +VL  +E   N F +FT   + +    L  + I E  K   + +    E+I+ H  YLINLG+P+    +      I E+ R NQ+  KL+  HPG+ L+    +  +  IA+++N A++   N VI  +E  AG+GS +G  FE +++I+  V++K R+GVCLDTCH+  +G DIS     +QT  EF + +   Y++ +HLN SK  +GSR DRH  +  G +G D+      +++  N+P ILET
  S:     4 IGAHV--SASGGVENAVLRAVEIGANAFALFTKNQRQWKAPALKADTI-EKFKRFCKAHQFSPEHILPHDSYLINLGNPEAENLAKSREAFIDEMERANQLGLKLLNFHPGAHLNKISESECLARIAESINIAVDKVPN-VIAVIENTAGQGSNLGYRFEHLAEIIDQVEDKNRVGVCLDTCHLFSAGYDISSLESCEQTFSEFERTVGFQYLRGMHLNGSKTPLGSRVDRHHTLREGTIGTDFCKFIMQDDRFDNIPLILET 262
>gi|117925233|ref|YP_865850.1| endonuclease IV [Magnetococcus sp. MC-1] >gi|166224283|sp|A0L901|END4_MAGSM Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|117608989|gb|ABK44444.1| Endonuclease IV [Magnetococcus sp. MC-1] (282 aa)
Score = 399, Expect = 6.4e-37, Identities = 88/245 (35%), Positives = 145/245 (59%)
  Q:    57 FMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           F +FT   + +  K +    I+   + M E    + E  + H  YLINLG+P  + R   L+  + E+ R  Q+   L+  HPGS L   D +  ++ I D+LN+A+E T   V+  +E  AG+GS +G  FE ++ I++GV++K RIGVCLDTCH   +G D+   +   +T++ F + +  SY++ +HLNDSK ++G++ DRH ++G GK+G +      ++ +L  +P ILET    D+ ++ QEI
  S:    29 FALFTKNQRQWTAKPITDAQIELFKRRMDEYG-FVPEQTLPHDSYLINLGNPDAAKRQQSLDAFVDEMQRCAQLGLPLLNFHPGSHLRQVDEDQCLDLIVDSLNRALERTSG-VVAVIENTAGQGSNLGYRFEHLAHIIAGVEDKSRIGVCLDTCHTFVAGYDLRTAEAYAKTMDTFEQVVGFSYLRGMHLNDSKPDLGAKVDRHHSLGAGKLGLETFRLIMNDGRLDGIPLILETI---DESLWAQEI 272
>gi|21673155|ref|NP_661220.1| endonuclease IV [Chlorobium tepidum TLS] >gi|39931162|sp|Q8KFL0|END4_CHLTE Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|21646233|gb|AAM71562.1| AP (apurinic or apyrimidinic) endonuclease, nfo family [Chlorobium tepidum TLS] (281 aa)
Score = 396, Expect = 1.2e-36, Identities = 80/211 (37%), Positives = 128/211 (60%)
  Q:    79 EAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           EA +   ++   L E+I+ H  YLINLG+P+           + E+ R   +   ++  HPGS L+ +D +  +  IA+++N++++AT   V   +E  AG+GS +G  FE +++I+  V++K R+GVCLDTCH+  SG D+  P   D TL EF + + L Y+K +HLND+K ++GS+ DRH+ +G G +G D       +  L  +P ILETP
  S:    50 EAFRRNCDEAGFLPEHILPHDSYLINLGAPEADKIEKSRKAFVTEMQRAEALGLTMLNFHPGSHLNLTDEDACLKTIAESVNRSLDATAG-VTAVIENTAGQGSNLGWRFEHLARIIELVEDKSRVGVCLDTCHLFASGYDLRTPEAFDATLREFDRVVGLLYLKGMHLNDAKQKLGSKVDRHECLGKGMIGIDAFAHIMRHPALEEIPLILETP 263
>gi|160887448|ref|ZP_02068451.1| hypothetical protein BACOVA_05467 [Bacteroides ovatus ATCC 8483] >gi|156107859|gb|EDO09604.1| hypothetical protein BACOVA_05467 [Bacteroides ovatus ATCC 8483] (277 aa)
Score = 396, Expect = 1.2e-36, Identities = 96/258 (37%), Positives = 148/258 (57%)
  Q:    51 EYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKE---KNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           E   N F +FT   + ++ K L +    E++ L KE   K     E I+ H  YLINLG P+E          + E+ R  Q+  KL+  HPGS+L+       ++ IA+++N A+E T   V   +E  AG+GS +G  F ++  I+  V +K R+GVCLDTCH + +G DI ++ D+  +EF K +  +Y++ +HLNDSK  +G+  DRHD+IG G +G  +  +   + +  N+P ILETP   D+  +K+EI  L S E
  S:    23 EIGANAFALFTKNQRQWVSKPLTE----ESISLFKENCEKYGFQPEYILPHDSYLINLGHPEEEGLQKSRAAFLDEMQRCEQLGLKLLNFHPGSSLNKISTEDCLSLIAESINLALEKTKG-VTAVIENTAGQGSNLGSEFWQLKYIIDRVNDKNRVGVCLDTCHTYTAGYDIVNEYDKVFDEFDKEVGFNYLRGMHLNDSKKALGTHVDRHDSIGEGLIGKAFFERLMQDSRFDNIPLILETP---DESKWKEEIAWLRSME 277
>gi|53712533|ref|YP_098525.1| endonuclease IV [Bacteroides fragilis YCH46] >gi|60680716|ref|YP_210860.1| endonuclease IV [Bacteroides fragilis NCTC 9343] >gi|81316216|sp|Q5LG28|END4_BACFN Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|81383209|sp|Q64WY5|END4_BACFR Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|52215398|dbj|BAD47991.1| endonuclease IV [Bacteroides fragilis YCH46] >gi|60492150|emb|CAH06913.1| putative endonuclease IV [Bacteroides fragilis NCTC 9343] (278 aa)
Score = 396, Expect = 1.2e-36, Identities = 94/251 (37%), Positives = 145/251 (57%)
  Q:    51 EYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKE---KNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID-ISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           E   N F +FT   + ++ K L +    ++++L KE   K     E I+ H  YLINLG P+E   +      + E+ R  Q+  KL+  HPGS L+       ++ IA+++N A+E T   V   +E  AG+GS +G  F ++  I+  V++K R+GVCLDTCH   +G D ++D D    EF + +   Y++ +HLNDSK E+GSR DRHD+IG G +GF +  K   + +  N+P ILET    D+ ++ +EI
  S:    23 EIGANAFALFTKNQRQWVSKPLTE----DSIRLFKENCEKFGFAPEYILPHDSYLINLGHPEEEGLTKSRAAFLDEMQRCEQLGLKLLNFHPGSHLNKISVEECLDRIAESINLALEKTKG-VTAVIENTAGQGSNLGNEFWQLKYIIDRVEDKSRVGVCLDTCHTFTAGYDFLNDYDDVFGEFGEVVGFEYLRGMHLNDSKKELGSRVDRHDSIGKGLIGFAFFEKLMKDPRFDNMPLILETI---DETLWPEEI 270
>gi|87310379|ref|ZP_01092509.1| endonuclease IV [Blastopirellula marina DSM 3645] >gi|87286878|gb|EAQ78782.1| endonuclease IV [Blastopirellula marina DSM 3645] (278 aa)
Score = 395, Expect = 1.7e-36, Identities = 92/238 (38%), Positives = 135/238 (56%)
  Q:    56 CFMVFTGPPQNFMRKEL---DQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEAT-DNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           C  +FT     +  KE+   D  L  +A+     K+PL       HA YLIN+GSPK        + +IVE+ R NQ+    +V+HPG+ +DS     I  +   L++ I AT D D I  +ET AG+GS +G  FE +  ++ GVK K R+GVCLDTCH+  +G  I    + + T ++F   + L  +K IHLNDSK  +GSR DRH++IG G +G +      ++ +   +P  LETP  D+
  S:    21 CVQLFTKNNNQWRAKEITDKDVKLFQDALGEKGVKHPL------SHASYLINMGSPKPELWEKSRDAMIVELQRANQLGIPYVVVHPGAFVDSSEEEGIAAVVKALDEVINATLDLDSICLLETTAGQGSCLGHTFEHLGAMLDGVKKKDRVGVCLDTCHIFAAGYPIGTEKEYEATWKQFESLIGLDKLKAIHLNDSKKPLGSRVDRHEHIGEGCLGIEPFRLLVNDARFKTMPMYLETPKGDE 259
>gi|86147392|ref|ZP_01065705.1| endonuclease IV [Vibrio sp. MED222] >gi|85834820|gb|EAQ52965.1| endonuclease IV [Vibrio sp. MED222] (302 aa)
Score = 395, Expect = 1.7e-36, Identities = 97/279 (34%), Positives = 152/279 (54%)
  Q:    26 NKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           N   +G+HV   A   +  + +   E   N F +FT   + +  K L+   I  A K   +      E+I+ H  YLINLG+P+E          I E+ R NQ+   L+  HPGS L     +  +  IA+++N A +A   DVI  +E  +G+G+ +G  FE++++I+  V++K R+GVCLDTCH   +G D+      D T  EF + + + Y++ +H+NDSK E  SR DRH ++G G++G+D     A + +   +P ILET    D  I+K+EI  L
  S:    13 NIKFIGAHV--SAAGGVDQAPMRAREIGANAFALFTKNQRQWAAKPLEAKTI-SAFKANCKMLGFSAEHILPHDSYLINLGAPEEEKLEKSRAAFIDEMERCNQLGLTLLNFHPGSHLKKISESECLAKIAESINLAHQAVP-DVIAVIENTSGQGTNLGWKFEQLAEIIDQVEDKSRVGVCLDTCHTFTAGYDLRTKEACDHTFAEFDRIVGMHYLRAMHINDSKAEFASRVDRHHSLGKGEIGWDCFEYIASDSRFNGIPLILETI---DSTIWKEEIQQL 288
>gi|189467635|ref|ZP_03016420.1| hypothetical protein BACINT_04025 [Bacteroides intestinalis DSM 17393] >gi|189435899|gb|EDV04884.1| hypothetical protein BACINT_04025 [Bacteroides intestinalis DSM 17393] (278 aa)
Score = 395, Expect = 1.7e-36, Identities = 94/258 (36%), Positives = 145/258 (56%)
  Q:    51 EYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           E   N F +FT   + ++ K L +  I E  K   EK       I+ H  YLINLG P+E          + E+ R  Q+  +L+  HPGS L+       ++ +A+++N  +  T   V   +E  AG+GS VG  F ++  I+  V++K R+GVCLDTCH + +G DI  + D+   EF + +  +Y++ IHLND+K E+GS  DRHD+IG G +G D+  ++  +E+  N+P ILETP   D+ ++ +EI  L S E
  S:    24 EIGANAFALFTKNQRQWVAKPLTEESIRE-FKGNCEKFSFDARYILPHDSYLINLGHPEEEGLEKSRAAFLDEMQRCEQLGLQLLNFHPGSHLNKISVEECLDKVAESINITLSKTKG-VTAVIENTAGQGSNVGNEFWQLKHIIDRVEDKSRVGVCLDTCHTYSAGYDIVGEYDKVFREFDEVVGFNYLRGIHLNDTKKELGSHVDRHDSIGKGLLGIDFFKRFMKDERFDNMPVILETP---DETLWAEEIKLLRSFE 278
>gi|91226797|ref|ZP_01261450.1| endonuclease IV [Vibrio alginolyticus 12G01] >gi|91188928|gb|EAS75212.1| endonuclease IV [Vibrio alginolyticus 12G01] (294 aa)
Score = 395, Expect = 1.9e-36, Identities = 103/284 (36%), Positives = 159/284 (55%)
  Q:    21 MCMSKNKL---LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           M   KNKL   L+G+HV   A   +  + L   E   N F +FT   + ++ K L+   I  A K   +      E+I+ H  YLINLG+P+E   +      I E+ R NQ+   L+  HPGS L        +  IA+++N A +A  N VI  +E  AG+G+ +G  FE +++I+  V++K R+GVC+DTCH   +G D+    D ++T  EF + + + Y++ +HLNDSK E  S+ DRH ++G G++G+D     A + +   +P ILET    D  I++QEI  L
  S:     1 MTNMKNKLGNKLIGAHV--SAAGGVDQAPLRAREIGANAFALFTKNQRQWVAKPLEVKTI-SAFKANCKMLGFGAEHILPHDSYLINLGAPEEEKLNKSRAAFIDEMERCNQLGLTLLNFHPGSHLKKVSEQECLATIAESINLAHKAVPN-VIAVIENTAGQGTNLGWKFEHLAEIIEQVEDKDRVGVCIDTCHTFTAGYDLRTKEDCERTFAEFDRIVGMHYLRAMHLNDSKVEFASKVDRHHSLGKGEIGWDCFEYIAKDPRFDGIPLILETI---DPDIWQQEINTL 284
>gi|50424751|ref|XP_460965.1| hypothetical protein DEHA0F15015g [Debaryomyces hansenii CBS767] >gi|49656634|emb|CAG89323.1| unnamed protein product [Debaryomyces hansenii CBS767] (334 aa)
Score = 395, Expect = 1.9e-36, Identities = 83/248 (33%), Positives = 141/248 (56%)
  Q:    54 GNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDL---SYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
            N F +F   P+ ++  ++ ++ + +  +L ++       +I+ H  Y INL +P            + ++ R  +++  L   HPGS+LD D   A+  +ADN+N+AI+ T+  V I +E MAG G+ +G N +++  ++  V++K R+GVC+DTCH   +G DIS+ ++  E F  + D     Y+  IHLNDSK  +G+ +D H  +GYG +G +     A+  KL N+P +LETP   D  +Y +EI
  S:    17 ANSFALFLKSPRKWVSPDIKEDEVAKFAELCQKYGYNPRTDILPHGSYFINLANPDAEKEEKAYGSFLDDLKRCEKLNIGLYNFHPGSSLDGDHKEALKRLADNINRAIKDTEF-VKIVIENMAGHGNLIGSNLQDIKDVIDMVEDKTRVGVCIDTCHTFAAGYDISNQEKFDEFFKLFEDTIGWEYLSAIHLNDSKAPLGANRDLHQKLGYGFLGLEVFRIIANFPKLQNIPIVLETPVDKDDTVYGEEI 266
>gi|153807794|ref|ZP_01960462.1| hypothetical protein BACCAC_02077 [Bacteroides caccae ATCC 43185] >gi|149129403|gb|EDM20617.1| hypothetical protein BACCAC_02077 [Bacteroides caccae ATCC 43185] (290 aa)
Score = 394, Expect = 2.3e-36, Identities = 99/284 (34%), Positives = 159/284 (55%)
  Q:    25 KNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKE---KNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +N   +G+HV   A   +  + +   E   N F +FT   + ++ K L +    E+++L KE   K     E I+ H  YLINLG P+E   +      + E+ R  Q+  +L+  HPGS+L+       ++ IA+++N  +E T   V   +E  AG+GS +G  F ++  I+  V +K R+GVCLDTCH + +G DI +D D+  EEF K +  +Y++ +HLNDSK  +G+  DRHD+IG G +G  +  +   + +  N+P +LETP   D+  + +EI  L S E
  S:    12 QNMKYIGAHV--SASGGVEFAPINAHEIGANAFALFTKNQRQWISKPLSE----ESIRLFKENCDKYGFQPEYILPHDSYLINLGHPEEEGLNKSRAAFLDEMQRCEQLGLRLLNFHPGSSLNKIATEDCLSLIAESINITLEKTKG-VTAVIENTAGQGSNLGSEFWQLKYIIDRVDDKSRVGVCLDTCHTYTAGYDIVNDYDKVFEEFDKEVGFNYLRGMHLNDSKKALGTHVDRHDSIGEGLIGKAFFERLMQDSRFDNIPLVLETP---DESKWAEEIAWLRSVE 290
>gi|90413169|ref|ZP_01221165.1| endonuclease IV [Photobacterium profundum 3TCK] >gi|90325860|gb|EAS42312.1| endonuclease IV [Photobacterium profundum 3TCK] (282 aa)
Score = 394, Expect = 2.4e-36, Identities = 95/278 (34%), Positives = 157/278 (56%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           L+G+HV   A   +  +     +   N F +FT   + ++ K L+Q++I  A K   ++     E I+ H  YLINLG+P+           I E+ R NQ+   L+  HPGS L     +  +  IA+++N A +    DV+  +E  AG+GS +G  FE +++I+  V++K R+GVC+DTCH   +G D+   S  + T  EF + + +S+++ +HLNDSK ++GS  DRH ++G G++G+D       + +  N+P +LET   D   I++QEI+ L S
  S:     3 LIGAHV--SAAGGVFNAPENAAKIGANAFALFTKNQRQWVAKPLEQDVII-AFKARCQQYEFKSEAILPHDSYLINLGNPETEKLEKSRAAFIDEMQRCNQLGLTLLNFHPGSHLKKISESDCLRLIAESINMAHQEVP-DVVAVIENTAGQGSNLGWRFEHLAEIIEQVEDKSRVGVCIDTCHTFAAGYDLRSESATEATFAEFDQTVGMSFLRGMHLNDSKGKLGSHLDRHHSLGEGEIGWDCFRYLMQDSRFDNIPLVLETINPD---IWQQEIMTLRS 277
>gi|84995328|ref|XP_952386.1| apurinic/apyrimidinic endonuclease Apn1-like, putative [Theileria annulata] >gi|65302547|emb|CAI74654.1| apurinic/apyrimidinic endonuclease Apn1-like, putative [Theileria annulata] (420 aa)
Score = 393, Expect = 2.7e-36, Identities = 96/277 (34%), Positives = 158/277 (57%)
  Q:    25 KNKLLLGSHVGFKA-KNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKN--PLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRD-DKPIYKQEI 301
           K+ + +G+HV       Y V +    L   G  F +F    + +  K L ++ I++    M   N  P     ++ HA YLIN+ +P    R+   +  + +I R  Q+  KL   HPGS     ++   I HI+D +NKA+E T   V I +E  AG+ + +G  F+++ +I++ V++K R+GVCLDTCH+  +G DI      DQ +++F   + L Y++ +HLNDSK+++GS  DRH+NIG GK+  +      ++    N+P ILETP  + ++ +YKQE+
  S:   135 KSNVYIGAHVSASGGPEYSVPNAYNIL---GQSFALFLKNQRTWNWKALSKSAIEKFKSNMSSHNYDPKF---VLPHASYLINMANPDPDKRNRAFDNFLDDIQRCEQLGIKLYNFHPGSTCGLCEKKEGIKHISDCINKALEMTKG-VTIVLENAAGQKNVIGSKFDDLKQIIANVEDKSRVGVCLDTCHLFAAGYDIRTTEQFDQVMKDFDSVVGLKYLRAVHLNDSKSDLGSGLDRHENIGKGKLSEETFRFIVNSPYFKNIPIILETPVTEGNEGVYKQEV 412
>gi|157738420|ref|YP_001491104.1| endonuclease IV [Arcobacter butzleri RM4018] >gi|189037119|sp|A8EWW1|END4_ARCB4 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|157700274|gb|ABV68434.1| endonuclease IV [Arcobacter butzleri RM4018] (280 aa)
Score = 393, Expect = 2.8e-36, Identities = 93/275 (33%), Positives = 155/275 (56%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           +G+HV   A   +  + +   +     F +FT   + +  K LD   ID   K + EK+ +  ++I+ H  YLINLG P    R   +   + E+ R   +    +  HPGS L        +++IA+++N+ I+ T   V + +E  AG+GS +G  FE ++ I+  +++K R+GVC+DTCHM  +G DI      D+T  EF K +   Y+  +H+NDSK E+GSR DRHD++G GK+G+D      +++++ ++P +LET    D+ I+ +EI  L
  S:     4 IGAHV--SASGGVFNAPINATQIGAKAFALFTKNQRQWSAKALDNKTIDLWFKEL-EKSKIEPKHILPHDSYLINLGHPDSDAREKSIESFLDEVQRCEILALDRLNFHPGSHLRKISEEECLDNIAESMNRVIDKTSG-VKLVIENTAGQGSNLGYKFEHLAYIIDKIEDKSRVGVCIDTCHMFTAGYDIRTREAYDKTWNEFEKIVGFKYLSGMHINDSKPELGSRVDRHDSLGCGKIGWDAFEFIMNDKRMNDIPLVLETI---DESIWAEEIKTL 275
>gi|189500810|ref|YP_001960280.1| apurinic endonuclease Apn1 [Chlorobium phaeobacteroides BS1] >gi|189496251|gb|ACE04799.1| apurinic endonuclease Apn1 [Chlorobium phaeobacteroides BS1] (284 aa)
Score = 393, Expect = 2.8e-36, Identities = 101/279 (36%), Positives = 148/279 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQT---LEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV       +  + L   E     F +FT   + +    L    I EA +   E+     E+I+ H  YLINLGSP         N  I E+ RT  +    + LHPGS L +S     +  IA+++N A EAT N  +  +E  AG+GS +G  FE+++ I+  V +K R+GVCLDTCH+  +G D+   +      E F   + L Y+K +HLND+K E+ SR+DRH++IG GK+G D       +   A +P ILETP  +   I+ +EI  L S E
  S:     4 IGAHVSIAGG--IENAPLRAQEIGATAFALFTKNQRQWKAPALTAKTI-EAFRENCERCGYRPEHILPHDSYLINLGSPDAQKLDRSRNAFIDEMQRTEALGLVRLNLHPGSHLRESSEEACLETIAESVNLAHEAT-NTAVAVLENTAGQGSNLGHTFEQLAFIIQRVHDKSRVGVCLDTCHLFAAGYDLRTEEAVNGMFELFDASIGLHYLKGMHLNDAKPELDSRRDRHESIGKGKIGLDGFAAIIRHPASAEIPLILETPQPE---IWSEEITLLRSFE 279
>gi|24113546|ref|NP_708056.1| endonuclease IV [Shigella flexneri 2a str. 301] >gi|30063600|ref|NP_837771.1| endonuclease IV [Shigella flexneri 2a str. 2457T] >gi|110806135|ref|YP_689655.1| endonuclease IV [Shigella flexneri 5 str. 8401] >gi|123342698|sp|Q0T2W5|END4_SHIF8 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|39931103|sp|Q83QW6|END4_SHIFL Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|24052593|gb|AAN43763.1| endonuclease IV [Shigella flexneri 2a str. 301] >gi|30041853|gb|AAP17580.1| endonuclease IV [Shigella flexneri 2a str. 2457T] >gi|110615683|gb|ABF04350.1| endonuclease IV [Shigella flexneri 5 str. 8401] (285 aa)
Score = 393, Expect = 3.0e-36, Identities = 94/279 (33%), Positives = 146/279 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       N++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQNDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|194539240|ref|YP_002074295.1| endonuclease 4 [Vibrio sp. Ex25] >gi|151937795|gb|EDN56643.1| endonuclease 4 [Vibrio sp. Ex25] (295 aa)
Score = 393, Expect = 3.1e-36, Identities = 102/281 (36%), Positives = 156/281 (55%)
  Q:    21 MCMSKNKL---LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           M   KNKL   L+G+HV   A   +  + L   E   N F +FT   + ++ K L+   I  A K   +      E+I+ H  YLINLG+P+           I E+ R NQ+   L+  HPGS L        +  IA+++N A +A  N VI  +E  AG+G+ +G  FE +++I+  V++K+R+GVCLDTCH   +G D+    D + T  EF + + + Y++ +HLNDSK E  S+ DRH ++G G++G+D     A + +   +P ILET    D  I++QEI
  S:     1 MTNMKNKLGNKLIGAHV--SAAGGVDQAPLRAREIGANAFALFTKNQRQWVAKPLEAKTI-SAFKANCKMLGFGAEHILPHDSYLINLGAPEADKLDKSRAAFIDEMERCNQLGLTLLNFHPGSHLKKVSEQECLATIAESINLAHKAVPN-VIAVIENTAGQGTNLGWKFEHLAEIIDQVEDKERVGVCLDTCHTFTAGYDLRTKEDCEHTFAEFDRIVGMHYLRAMHLNDSKVEFASKVDRHHSLGKGEIGWDCFEYIAKDPRFDGIPLILETI---DPDIWQQEI 281
>gi|150863969|ref|XP_001382630.2| hypothetical protein PICST_30161 [Pichia stipitis CBS 6054] >gi|149385225|gb|ABN64601.2| predicted protein [Pichia stipitis CBS 6054] (379 aa)
Score = 391, Expect = 5.0e-36, Identities = 88/274 (32%), Positives = 148/274 (54%)
  Q:    24 SKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQ---TLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIY 297
           + +K   G+HVG  A   +  SV+       N F +F   P+ ++   +    ID+   L +E       +++ H  Y INL +P         +  + +++R  Q++  L   HPGS+LD D   A+  +A N+N+AI+ T + V I +E MAG G+ +G N +++  ++  V++K R+GVC+DTCH   +G DIS  ++     +EF   +   ++  IHLNDSK  +G+ +D H  +G G +G +     A++ +L N+P ILETP  +D   Y
  S:    37 TTSKFKFGAHVG--ASGGVSNSVINARNLGANSFALFLKSPRKWVSPPISAEEIDKFKSLCEEHGYDPRTDVLPHGSYFINLANPDPEKEEKAFDGFLDDLHRCEQLNIGLYNFHPGSSLDGDHREALERLAKNINRAIKET-SFVKIVIENMAGHGNLIGSNLQDIRDVIDIVEDKSRVGVCVDTCHTFAAGYDISTEEKFEAFWKEFDNIVGAEFLSAIHLNDSKAPLGANRDLHQFLGQGFLGLEAFRVVANSPRLHNIPIILETPVGNDDSYY 310
>gi|163914965|ref|NP_001106474.1| hypothetical protein LOC100127659 [Xenopus tropicalis] >gi|158253664|gb|AAI54097.1| Unknown (protein for MGC:172934) [Xenopus tropicalis] (363 aa)
Score = 390, Expect = 5.8e-36, Identities = 94/268 (35%), Positives = 148/268 (55%)
  Q:    26 NKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           +K  +G+HV  +   +   +VL   +   +   +F G  + +  K LD    +   +  KE        I+ H+PYL+NLGSPK          L+ E+++ +Q+   +  +HPGS + +   +  +  IAD +N A  A    VI+ +E M+ +GS VG  FEE+  I+  V +K RIGVCLDTCH   +G D+S     +  L+EF+K + LS++K IHLNDS+ E+G + DRH+NIG+G +G +      +  +   +P ILETP   D
  S:    70 SKKFVGAHVSIQGGIW--NAVLVARQIGASAIGMFLGSQRTWKSKALDDKAAERFQRTCKELG-FKSRYILPHSPYLMNLGSPKPDVLQKSQAMLVDELHKCHQLGLTMYNIHPGSCVGAMSVSKCLELIADGINLA-HAQVPGVIVVLENMSCQGSTVGGRFEELRGIIDLVVDKSRIGVCLDTCHAFAAGHDLSKKAGLEHMLDEFNKVVGLSFLKAIHLNDSQGELGCKLDRHENIGHGHIGLEGFRHVMNEPRFNGIPMILETPLSSD 337
>gi|29350059|ref|NP_813562.1| endonuclease IV [Bacteroides thetaiotaomicron VPI-5482] >gi|39931125|sp|Q89YT0|END4_BACTN Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|29341971|gb|AAO79756.1| endonuclease IV [Bacteroides thetaiotaomicron VPI-5482] (277 aa)
Score = 390, Expect = 5.9e-36, Identities = 97/258 (37%), Positives = 146/258 (56%)
  Q:    51 EYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKE---KNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINH----IADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           E   N F +FT   + ++ K L +    E ++L KE   K     + I+ H  YLINLG P+E          + E+ R  Q+  KL+  HPGS L+    ++I      IA+++N  +E T   V   +E  AG+GS +G  F ++  I+  V +K R+G+CLDTCH + +G DI +D D+  +EF K +   Y++ +HLNDSK E+GS  DRHDNIG G +G  +  +   + +  N+P ILETP   D+  + +EI  L S E
  S:    23 EIGANAFALFTKNQRQWVSKPLKE----ENIRLFKENCTKYNFQTDYILPHDSYLINLGHPEEEGLEKSRAAFLDEMQRCEQLGLKLLNFHPGSHLN---KISIEDCLALIAESINLTLEKTKG-VTAVIENTAGQGSNLGSEFWQLRYIIDRVNDKSRVGICLDTCHTYTAGYDIVNDYDKVFDEFEKEVGFEYLRGMHLNDSKKELGSHVDRHDNIGQGLIGSAFFERLMKDSRFDNMPLILETP---DESKWAEEIAWLRSVE 277
>gi|171068|gb|AAA34429.1| apurinic endonuclease (APN1) (367 aa)
Score = 390, Expect = 6.2e-36, Identities = 93/267 (34%), Positives = 140/267 (52%)
  Q:    45 SVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           SV        N F +F   P+ ++  +  Q  ID+  K     N   L +++ H  Y INL +P            + ++NR  Q+   L  LHPGS L  D  + +  +A  LNKAI+ T   V I +E MAG G+ VG +  ++ +++  +++K RIGVC+DTCH   +G DIS  +      +EF+  +   Y+  +HLNDSK  +GS +D H+ +G G +G D     AH+E L  +P +LETPY +D+  Y  EI      EW E
  S:    30 SVTNAFNTGCNSFAMFLKSPRKWVSPQYTQEEIDKFKKNCATYNYNPLTDVLPHGQYFINLANPDREKAEKSYESFMDDLNRCEQLGIGLYNLHPGSTLKGDHQLQLKQLASYLNKAIKET-KFVKIVLENMAGTGNLVGSSLVDLKEVIGMIEDKSRIGVCIDTCHTFAAGYDISTTETFNNFWKEFNDVIGFKYLSAVHLNDSKAPLGSNRDLHERLGQGYLGIDVFRMIAHSEYLQGIPIVLETPYENDEG-YGNEI---KLMEWLE 294
>gi|32035806|ref|ZP_00135650.1| COG0648: Endonuclease IV [Actinobacillus pleuropneumoniae serovar 1 str. 4074] >gi|126207842|ref|YP_001053067.1| endonuclease IV [Actinobacillus pleuropneumoniae L20] >gi|166224268|sp|A3MZ76|END4_ACTP2 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|126096634|gb|ABN73462.1| putative endonuclease 4 [Actinobacillus pleuropneumoniae L20] (280 aa)
Score = 390, Expect = 6.5e-36, Identities = 91/259 (35%), Positives = 145/259 (55%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDIS---DPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILET 288
           +G+HV   A   +  +VL  +E   N F +FT   + +    L  + I E  K   + +    E+I+ H  YLINLG+P+    +      I E+ R NQ+  KL+  HP + L+    +  +  IA+++N A++   N VI  +E  AG+GS +G  FE +++I+  V++K R+GVCLDTCH+  +G DIS     +QT  EF + +   Y++ +HLN SK  +GSR DRH  +  G +G D+      +++  N+P ILET
  S:     4 IGAHV--SASGGVENAVLRAVEIGANAFALFTKNQRQWKALALKADTI-EKFKRFCKAHQFSPEHILPHDSYLINLGNPEAENLAKSREAFIDEMERANQLGLKLLNFHPSAHLNKISESECLARIAESINIAVDKVPN-VIAVIENTAGQGSNLGYRFEHLAEIIDQVEDKNRVGVCLDTCHLFSAGYDISSLESCEQTFSEFERTVGFQYLRGMHLNGSKTPLGSRVDRHHTLREGTIGTDFCKFIMQDDRFDNIPLILET 262
>gi|156973263|ref|YP_001444170.1| endonuclease IV [Vibrio harveyi ATCC BAA-1116] >gi|166224295|sp|A7MS84|END4_VIBHB Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|156524857|gb|ABU69943.1| hypothetical protein VIBHAR_00944 [Vibrio harveyi ATCC BAA-1116] (295 aa)
Score = 389, Expect = 7.6e-36, Identities = 98/276 (35%), Positives = 153/276 (55%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
            +G+HV   A   +  + L   E   N F +FT   + ++ K L++  I  A K   +      E+I+ H  YLINLG+P+E   +      I E+ R NQ+   L+  HPGS L        +  IA+++N A +A  N VI  +E  AG+G+ +G  FE +++I+  V+NK+R+GVCLDTCH   +G D+    D + T  EF + + + Y++ +HLNDSK E  S+ DRH ++G G++G+      A + +   +P ILET    D  I++QEI  L
  S:    12 FIGAHV--SAAGGVDQAPLRAREIGANAFALFTKNQRQWVAKPLEEKTI-SAFKANCKMLGFGAEHILPHDSYLINLGAPEEEKLNKSRAAFIDEMERCNQLGLTLLNFHPGSHLKKVSEQECLATIAESINLAHKAVPN-VIAVIENTAGQGTNLGWKFEHLAEIIDQVENKERVGVCLDTCHTFTAGYDLRTKEDCEHTFAEFDRVVGMHYLRAMHLNDSKVEFASKVDRHHSLGKGEIGWSCFEYIAKDPRFDGIPLILETI---DPDIWQQEINTL 284
>gi|148981665|ref|ZP_01816488.1| endonuclease IV [Vibrionales bacterium SWAT-3] >gi|145960788|gb|EDK26124.1| endonuclease IV [Vibrionales bacterium SWAT-3] (302 aa)
Score = 389, Expect = 8.4e-36, Identities = 96/279 (34%), Positives = 150/279 (53%)
  Q:    26 NKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           N   +G+HV   A   +  + +   E   N F +FT   + +  K L+   I  A K   +      E+I+ H  YLINLG+P+E          I E+ R NQ+   L+  HPGS L        +  IA+++N A +A   DVI  +E  +G+G+ +G  FE +++I+  V++K R+GVCLDTCH   +G D+      + T  EF + + + Y++ +H+NDSK E  SR DRH ++G G++G+D     A + +   +P ILET    D  I+K+EI  L
  S:    13 NIKFIGAHV--SAAGGVDQAPMRAREIGANAFALFTKNQRQWAAKPLEAKTI-SAFKANCKMLGFSAEHILPHDSYLINLGAPEEEKLEKSRAAFIDEMERCNQLGLTLLNFHPGSHLKKISETECLAKIAESINLAHQAVP-DVIAVIENTSGQGTNLGWKFEHLAEIIEQVEDKSRVGVCLDTCHTFTAGYDLRTKEACEHTFAEFDRIVGMHYLRAMHINDSKAEFASRVDRHHSLGKGEIGWDCFEYIASDSRFNGIPLILETI---DSTIWKEEIQQL 288
>gi|157749531|ref|XP_001678479.1| Hypothetical protein CBG13421 [Caenorhabditis briggsae AF16] >gi|187028671|emb|CAP32198.1| C. briggsae CBR-APN-1 protein [Caenorhabditis briggsae] (389 aa)
Score = 389, Expect = 8.4e-36, Identities = 79/233 (33%), Positives = 139/233 (59%)
  Q:    57 FMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           F +F    + +  K +++++++   K ++E     L  IV H  YL+N GSP+E       N ++ E  R  ++   +   HPGS +   +R   ++ IA+ ++  +E T+  +++ +ETMAG+G+ +G  FEE+  ++  VKNK R+GVC+DTCH+  +G DI      ++ + +F   +  +Y+K +H+NDSK ++ S  DRH++IG GK+G D      ++E+L  +P ILETP
  S:   138 FAMFVRNQRTWNHKPMEESVVENWWKAVRETE-FPLGQIVPHGSYLMNAGSPEEEKLEKSRNAMVDECQRAEKLGITMYNFHPGSTVGKCEREKCMDTIAETIDYVVERTEK-IVLVLETMAGQGNSIGGTFEELKYVIDRVKNKSRVGVCIDTCHIFAAGYDIRSEKAYEEVMSKFEATIGWNYLKAMHINDSKGDLRSNLDRHEHIGQGKIGKDAFGFLMNDERLKGIPMILETP 372
>gi|167760566|ref|ZP_02432693.1| hypothetical protein CLOSCI_02940 [Clostridium scindens ATCC 35704] >gi|167661787|gb|EDS05917.1| hypothetical protein CLOSCI_02940 [Clostridium scindens ATCC 35704] (279 aa)
Score = 389, Expect = 8.9e-36, Identities = 94/280 (33%), Positives = 147/280 (52%)
  Q:    23 MSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLID--EAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEII 302
           M +  L +G+H+   AK  +  +    +E   N   +F+  P+    K   +  I   + ++   +  PLL      HAPY +NL S KE         +  +I R + +  + IV HPGS         I +I   L++AI   D ++++ +ETM GKG+E+G  FE +  I  GV++ +RIG+CLDTCH+  +G DI  + D  LEEF + + L  +K +H NDS    GS KDRH  IG G++G + L++   +  L  +P  LETP  D +   + E+I
  S:     1 MEEKMLTIGTHMSI-AKG-IAKTAENVVEMKANTMQIFSRNPRGSNYKTYTEEEIGRFQEIRRKNQFGPLL-----AHAPYTMNLASDKEKVYEFACTVIREDIARMDALGIENIVFHPGSHTGIGIEAGIRNIIAGLDQAITG-DENIMVLLETMTGKGTEIGAKFEHLRAIRDGVRHPERIGICLDTCHVFAAGYDIVGNLDGVLEEFDRVIGLDLLKAVHFNDSMMPFGSHKDRHSTIGAGEIGLEPLLRVMRHPALKELPFYLETPLEDAEHKIEIEMI 275
>gi|194431425|ref|ZP_03063717.1| endonuclease 4 [Shigella dysenteriae 1012] >gi|194420250|gb|EDX36327.1| endonuclease 4 [Shigella dysenteriae 1012] (285 aa)
Score = 389, Expect = 9.3e-36, Identities = 93/279 (33%), Positives = 146/279 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETITPD---IWAEEIAWLKAQQ 279
>gi|405898|gb|AAA60529.1| endonuclease IV [Escherichia coli] >gi|744194|prf||2014253BE endonuclease (285 aa)
Score = 388, Expect = 9.7e-36, Identities = 93/279 (33%), Positives = 146/279 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEITWLKAQQ 279
>gi|33152191|ref|NP_873544.1| endonuclease IV [Haemophilus ducreyi 35000HP] >gi|39931014|sp|Q7VMC4|END4_HAEDU Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|33148413|gb|AAP95933.1| endonuclease IV [Haemophilus ducreyi 35000HP] (281 aa)
Score = 388, Expect = 1.0e-35, Identities = 93/259 (35%), Positives = 153/259 (59%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD--SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISD---PDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILET 288
           +G+HV   A   +  +VL  +E  GN F +FT   + +    L    I E  K   + +    + I+ H  YLINLG P+   R   +   I E+ R NQ+  KL+  HPGS L+  S+R+  + +IA+++N AI+   N V+  +E  AG+GS +G  FE +++I+  V++K R+GVCLDTCH+  +G DIS     ++T  +F + +  ++++ +HLN SK  +GSR DRH  +  G +G   F+Y+++   + +  ++P ILET
  S:     4 IGAHV--SAAGGVENAVLRAVEIGGNAFALFTKNQRQWQAATLKAETI-EKFKRFCQVHQFTADQILPHDSYLINLGHPELENRQKSVAAFIDEMQRVNQLGLKLLNFHPGSHLNKISERD-CLAYIAESINIAIKTVPN-VVAVIENTAGQGSNMGYRFEHLAEIIEQVEDKSRVGVCLDTCHLFSAGYDISSWQACEKTFTDFDQIVGYAFLRGMHLNGSKTALGSRVDRHHCLRDGTIGTAVFEYIMQ---HHQFDHIPLILET 262
>gi|82544623|ref|YP_408570.1| endonuclease IV [Shigella boydii Sb227] >gi|157158335|ref|YP_001463512.1| endonuclease IV [Escherichia coli E24377A] >gi|157161641|ref|YP_001458959.1| endonuclease IV [Escherichia coli HS] >gi|170019524|ref|YP_001724478.1| apurinic endonuclease Apn1 [Escherichia coli ATCC 8739] >gi|188492385|ref|ZP_02999655.1| endonuclease 4 [Escherichia coli 53638] >gi|191165384|ref|ZP_03027226.1| endonuclease 4 [Escherichia coli B7A] >gi|193062462|ref|ZP_03043557.1| endonuclease 4 [Escherichia coli E22] >gi|193071088|ref|ZP_03052014.1| endonuclease 4 [Escherichia coli E110019] >gi|194427223|ref|ZP_03059774.1| endonuclease 4 [Escherichia coli B171] >gi|123559243|sp|Q31YW6|END4_SHIBS Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|166920082|sp|A7ZNY3|END4_ECO24 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|166920083|sp|A8A222|END4_ECOHS Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|189037124|sp|B1IYB0|END4_ECOLC Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|81246034|gb|ABB66742.1| endonuclease IV [Shigella boydii Sb227] >gi|157067321|gb|ABV06576.1| endonuclease 4 [Escherichia coli HS] >gi|157080365|gb|ABV20073.1| endonuclease 4 [Escherichia coli E24377A] >gi|169754452|gb|ACA77151.1| apurinic endonuclease Apn1 [Escherichia coli ATCC 8739] >gi|188487584|gb|EDU62687.1| endonuclease 4 [Escherichia coli 53638] >gi|190904547|gb|EDV64254.1| endonuclease 4 [Escherichia coli B7A] >gi|192932128|gb|EDV84727.1| endonuclease 4 [Escherichia coli E22] >gi|192955611|gb|EDV86088.1| endonuclease 4 [Escherichia coli E110019] >gi|194414844|gb|EDX31115.1| endonuclease 4 [Escherichia coli B171] (285 aa)
Score = 388, Expect = 1.1e-35, Identities = 93/279 (33%), Positives = 146/279 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|26248542|ref|NP_754582.1| endonuclease IV [Escherichia coli CFT073] >gi|110642369|ref|YP_670099.1| endonuclease IV [Escherichia coli 536] >gi|191170018|ref|ZP_03031572.1| endonuclease 4 [Escherichia coli F11] >gi|122958208|sp|Q0TFT1|END4_ECOL5 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|29427791|sp|Q8FFU0|END4_ECOL6 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|26108947|gb|AAN81150.1|AE016763_109 Endonuclease IV [Escherichia coli CFT073] >gi|110343961|gb|ABG70198.1| endonuclease IV [Escherichia coli 536] >gi|190909534|gb|EDV69119.1| endonuclease 4 [Escherichia coli F11] (285 aa)
Score = 388, Expect = 1.1e-35, Identities = 93/279 (33%), Positives = 146/279 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVAEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|6573704|pdb|1QTW|A Chain A, High-Resolution Crystal Structure Of The Escherichia Coli Dna Repair Enzyme Endonuclease Iv (285 aa)
Score = 388, Expect = 1.2e-35, Identities = 93/279 (33%), Positives = 146/279 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|15832305|ref|NP_311078.1| endonuclease IV [Escherichia coli O157:H7 str. Sakai] >gi|16130097|ref|NP_416664.1| endonuclease IV with intrinsic 3'-5' exonuclease activity [Escherichia coli str. K-12 substr. MG1655] >gi|82777340|ref|YP_403689.1| endonuclease IV [Shigella dysenteriae Sd197] >gi|89108976|ref|AP_002756.1| endonuclease IV with intrinsic 3'-5' exonuclease activity [Escherichia coli W3110] >gi|168709874|ref|ZP_02742151.1| endonuclease IV [Escherichia coli O157:H7 str. EC4045] >gi|168733502|ref|ZP_02765779.1| endonuclease IV [Escherichia coli O157:H7 str. EC4115] >gi|168750545|ref|ZP_02775567.1| endonuclease 4 [Escherichia coli O157:H7 str. EC4113] >gi|168757747|ref|ZP_02782754.1| endonuclease 4 [Escherichia coli O157:H7 str. EC4401] >gi|168763821|ref|ZP_02788828.1| endonuclease 4 [Escherichia coli O157:H7 str. EC4501] >gi|168767778|ref|ZP_02792785.1| endonuclease 4 [Escherichia coli O157:H7 str. EC4486] >gi|168773124|ref|ZP_02798131.1| endonuclease 4 [Escherichia coli O157:H7 str. EC4196] >gi|168780008|ref|ZP_02805015.1| endonuclease 4 [Escherichia coli O157:H7 str. EC4076] >gi|168788974|ref|ZP_02813981.1| endonuclease 4 [Escherichia coli O157:H7 str. EC869] >gi|168792778|ref|ZP_02817785.1| endonuclease IV [Escherichia coli O157:H7 str. EC4042] >gi|168801146|ref|ZP_02826153.1| endonuclease 4 [Escherichia coli O157:H7 str. EC508] >gi|170081781|ref|YP_001731101.1| endonuclease IV with intrinsic 3'-5' exonuclease activity [Escherichia coli str. K12 substr. DH10B] >gi|195935538|ref|ZP_03080920.1| endonuclease IV [Escherichia coli O157:H7 str. EC4024] >gi|67462325|sp|P0A6C1|END4_ECOLI Endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|123562304|sp|Q32EQ7|END4_SHIDS Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|67462326|sp|P0A6C2|END4_ECO57 Endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|6137712|pdb|1QUM|A Chain A, Crystal Structure Of Escherichia Coli Endonuclease Iv In Complex With Damaged Dna >gi|1788483|gb|AAC75220.1| endonuclease IV with intrinsic 3'-5' exonuclease activity [Escherichia coli str. K-12 substr. MG1655] >gi|13362520|dbj|BAB36474.1| endonuclease IV [Escherichia coli O157:H7 str. Sakai] >gi|81241488|gb|ABB62198.1| endonuclease IV [Shigella dysenteriae Sd197] >gi|85675273|dbj|BAE76636.1| endonuclease IV with intrinsic 3'-5' exonuclease activity [Escherichia coli W3110] >gi|169889616|gb|ACB03323.1| endonuclease IV with intrinsic 3'-5' exonuclease activity [Escherichia coli str. K12 substr. DH10B] >gi|187771296|gb|EDU35140.1| endonuclease 4 [Escherichia coli O157:H7 str. EC4196] >gi|188015349|gb|EDU53471.1| endonuclease 4 [Escherichia coli O157:H7 str. EC4113] >gi|189002169|gb|EDU71155.1| endonuclease 4 [Escherichia coli O157:H7 str. EC4076] >gi|189355386|gb|EDU73805.1| endonuclease 4 [Escherichia coli O157:H7 str. EC4401] >gi|189362945|gb|EDU81364.1| endonuclease 4 [Escherichia coli O157:H7 str. EC4486] >gi|189366099|gb|EDU84515.1| endonuclease 4 [Escherichia coli O157:H7 str. EC4501] >gi|189371374|gb|EDU89790.1| endonuclease 4 [Escherichia coli O157:H7 str. EC869] >gi|189376626|gb|EDU95042.1| endonuclease 4 [Escherichia coli O157:H7 str. EC508] (285 aa)
Score = 388, Expect = 1.2e-35, Identities = 93/279 (33%), Positives = 146/279 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|149193722|ref|ZP_01870820.1| endonuclease IV [Caminibacter mediatlanticus TB-2] >gi|149135675|gb|EDM24153.1| endonuclease IV [Caminibacter mediatlanticus TB-2] (280 aa)
Score = 388, Expect = 1.2e-35, Identities = 93/257 (36%), Positives = 148/257 (57%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKIL 286
           +G+HV   A   +  +V+   E + N F +FT   + +  K L +  I +  +LM+E      ++++ H  YLINLG P+   R   LN  I E  R  ++  K +  HPGS L        ++ I D++N AI+ T N  I  +ET AG+GS +G  FE ++ I+ GV++K+RIGVC+DT H+  +G DI      D+T++EF + +   Y+K +H+NDSK +  SR DRH +IG G++G D       ++++ N+P IL
  S:     4 IGAHV--SAAGGVENAVINAKEINANGFALFTKNQRQWSAKPLSEKSIKKFKELMEEYG-FNADSVLPHDSYLINLGHPEIEKREKSLNAFIDEARRVEELGLKYLNFHPGSHLKKISEEECLDLIIDSINFAIKET-NSCIFVLETTAGQGSNLGYKFEHLAYIIDGVEDKERIGVCIDTAHIFAAGYDIRTKEAYDKTMQEFDEIIGFKYLKGMHINDSKAKFASRVDRHHSIGKGEIGLDAFKFIMQDKRIDNIPLIL 260
>gi|190409720|gb|EDV12985.1| major apurinic/apyrimidinic endonuclease/3'-repair diesterase [Saccharomyces cerevisiae RM11-1a] (367 aa)
Score = 388, Expect = 1.2e-35, Identities = 92/267 (34%), Positives = 140/267 (52%)
  Q:    45 SVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           SV        N F +F   P+ ++  +  Q  ID+  K     N   L +++ H  Y INL +P            + ++NR  Q+   L  LHPGS L  D  + +  +A  LNKAI+ T   V I +E MAG G+ VG +  ++ +++  +++K RIGVC+DTCH   +G DIS  +      +EF+  +   Y+  +HLNDSK  +G+ +D H+ +G G +G D     AH+E L  +P +LETPY +D+  Y  EI      EW E
  S:    30 SVTNAFNTGCNSFAMFLKSPRKWVSPQYTQEEIDKFKKNCATYNYNPLTDVLPHGQYFINLANPDREKAEKSYESFMDDLNRCEQLGIGLYNLHPGSTLKGDHQLQLKQLASYLNKAIKET-KFVKIVLENMAGTGNLVGSSLVDLKEVIGMIEDKSRIGVCIDTCHTFAAGYDISTTETFNNFWKEFNDVIGFKYLSAVHLNDSKAPLGANRDLHERLGQGYLGIDVFRMIAHSEYLQGIPIVLETPYENDEG-YGNEI---KLMEWLE 294
>gi|6322735|ref|NP_012808.1| Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine; Apn1p [Saccharomyces cerevisiae] >gi|543825|sp|P22936|APN1_YEAST DNA-(apurinic or apyrimidinic site) lyase 1 (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) >gi|1680184|gb|AAB22003.1|S93804_3 APN1/YKL513 gene product [Saccharomyces cerevisiae] >gi|486192|emb|CAA81954.1| APN1 [Saccharomyces cerevisiae] >gi|151941689|gb|EDN60051.1| major apurinic/apyrimidinic endonuclease/3'-repair diesterase [Saccharomyces cerevisiae YJM789] (367 aa)
Score = 388, Expect = 1.2e-35, Identities = 92/267 (34%), Positives = 140/267 (52%)
  Q:    45 SVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           SV        N F +F   P+ ++  +  Q  ID+  K     N   L +++ H  Y INL +P            + ++NR  Q+   L  LHPGS L  D  + +  +A  LNKAI+ T   V I +E MAG G+ VG +  ++ +++  +++K RIGVC+DTCH   +G DIS  +      +EF+  +   Y+  +HLNDSK  +G+ +D H+ +G G +G D     AH+E L  +P +LETPY +D+  Y  EI      EW E
  S:    30 SVTNAFNTGCNSFAMFLKSPRKWVSPQYTQEEIDKFKKNCATYNYNPLTDVLPHGQYFINLANPDREKAEKSYESFMDDLNRCEQLGIGLYNLHPGSTLKGDHQLQLKQLASYLNKAIKET-KFVKIVLENMAGTGNLVGSSLVDLKEVIGMIEDKSRIGVCIDTCHTFAAGYDISTTETFNNFWKEFNDVIGFKYLSAVHLNDSKAPLGANRDLHERLGQGYLGIDVFRMIAHSEYLQGIPIVLETPYENDEG-YGNEI---KLMEWLE 294
>gi|15802715|ref|NP_288742.1| endonuclease IV [Escherichia coli O157:H7 EDL933] >gi|25289189|pir||E85854 endonuclease IV [imported] - Escherichia coli (strain O157:H7, substrain EDL933) >gi|12516482|gb|AAG57297.1|AE005448_4 endonuclease IV [Escherichia coli O157:H7 EDL933] (285 aa)
Score = 387, Expect = 1.3e-35, Identities = 93/279 (33%), Positives = 146/279 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGBIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|74312681|ref|YP_311100.1| endonuclease IV [Shigella sonnei Ss046] >gi|123616766|sp|Q3Z047|END4_SHISS Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|73856158|gb|AAZ88865.1| endonuclease IV [Shigella sonnei Ss046] (285 aa)
Score = 387, Expect = 1.3e-35, Identities = 93/279 (33%), Positives = 147/279 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +  +E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAVEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKFRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|78778029|ref|YP_394344.1| endonuclease IV [Sulfurimonas denitrificans DSM 1251] >gi|123549708|sp|Q30PH2|END4_THIDN Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|78498569|gb|ABB45109.1| Endonuclease IV [Sulfurimonas denitrificans DSM 1251] (281 aa)
Score = 387, Expect = 1.5e-35, Identities = 94/279 (33%), Positives = 157/279 (56%)
  Q:    23 MSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           MSK    +G+HV   A   +  +V    +     F +FT   + +  KE D   ID+  K   EK+ +L  +++ H  YLINLG P+   R   L+  + E+ R + +    +  HPGS L     +  + +I++++N+ ++ T   V + +E  AG+GS +G  FE +++I+  V++K R+GVC+DTCHM  +G DI      D++  EF K +   Y+  +H+NDSK + GS  DRH+++G G++G D      ++E++ ++P ILET    D  I+ QEI
  S:     1 MSK---FVGAHV--SASGGVFNAVENAQKIGAKAFALFTKNQRQWSAKEFDSETIDK-FKTALEKSGILPRHVLPHDSYLINLGHPELDAREKSLDAFLDEVQRCSLLGLDRLNFHPGSHLKKISEDECLANISESMNRVLDKTSG-VSLVIENTAGQGSNLGWKFEHLAQIIDKVEDKSRVGVCIDTCHMFSAGYDIRTREAYDKSWGEFDKIVGFKYLMGMHINDSKAKFGSHVDRHNSLGVGEIGLDTFKFIMNDERMDDIPLILETI---DDSIWAQEI 273
>gi|157144896|ref|YP_001452215.1| endonuclease IV [Citrobacter koseri ATCC BAA-895] >gi|166224277|sp|A8AE66|END4_CITK8 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|157082101|gb|ABV11779.1| hypothetical protein CKO_00625 [Citrobacter koseri ATCC BAA-895] (285 aa)
Score = 386, Expect = 1.7e-35, Identities = 93/279 (33%), Positives = 145/279 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQ---TLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L   +ID+  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A+E T   V   +E  AG+GS +G  FE ++ I+ GV +K R+GVC+DTCH   +G D+   D+   T  +F + +  +Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTAQIIDD-FKAACEKYHYSPAQILPHDSYLINLGHPVSEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLQQIPEEECLARIAESINIALEKTQG-VTAVIENTAGQGSNLGFRFEHLAAIIDGVDDKSRVGVCIDTCHAFAAGYDLRTTDECEKTFADFERVVGFTYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|91211447|ref|YP_541433.1| endonuclease IV [Escherichia coli UTI89] >gi|117624359|ref|YP_853272.1| endonuclease IV [Escherichia coli APEC O1] >gi|122423208|sp|Q1R9R2|END4_ECOUT Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|166224279|sp|A1AD18|END4_ECOK1 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|91073021|gb|ABE07902.1| endonuclease IV [Escherichia coli UTI89] >gi|115513483|gb|ABJ01558.1| conserved hypothetical protein [Escherichia coli APEC O1] (285 aa)
Score = 385, Expect = 2.4e-35, Identities = 93/279 (33%), Positives = 145/279 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y+  +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVAEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLHGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|153835448|ref|ZP_01988115.1| endonuclease 4 [Vibrio harveyi HY01] >gi|148868011|gb|EDL67202.1| endonuclease 4 [Vibrio harveyi HY01] (295 aa)
Score = 385, Expect = 2.5e-35, Identities = 97/276 (35%), Positives = 153/276 (55%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
            +G+HV   A   +  + L   E   N F +FT   + ++ K L++  I  A K   +      E+I+ H  YLINLG+P+E   +      I E+ R NQ+   L+  HPGS L        +  IA+++N A +A  N VI  +E  AG+G+ +G  FE +++I+  V++K+R+GVCLDTCH   +G D+    D + T  EF + + + Y++ +HLNDSK E  S+ DRH ++G G++G+      A + +   +P ILET    D  I++QEI  L
  S:    12 FIGAHV--SAAGGVDQAPLRAREIGANAFALFTKNQRQWVAKPLEEKTI-SAFKANCKMLGFGAEHILPHDSYLINLGAPEEEKLNKSRAAFIDEMERCNQLGLTLLNFHPGSHLKKVSEQECLATIAESINLAHKAVPN-VIAVIENTAGQGTNLGWKFEHLAEIIDQVEDKERVGVCLDTCHTFTAGYDLRTKEDCEHTFAEFDRIVGMHYLRAMHLNDSKVEFASKVDRHHSLGKGEIGWSCFEYIAKDPRFDGIPLILETI---DPDIWQQEINTL 284
>gi|160285667|pdb|2NQH|A Chain A, High Resolution Crystal Structure Of Escherichia Coli Endonuclease Iv (Endo Iv) E261q Mutant >gi|160285671|pdb|2NQJ|A Chain A, Crystal Structure Of Escherichia Coli Endonuclease Iv (Endo Iv) E261q Mutant Bound To Damaged Dna >gi|160285672|pdb|2NQJ|B Chain B, Crystal Structure Of Escherichia Coli Endonuclease Iv (Endo Iv) E261q Mutant Bound To Damaged Dna (285 aa)
Score = 384, Expect = 2.8e-35, Identities = 92/279 (32%), Positives = 146/279 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P IL+T   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILQTINPD---IWAEEIAWLKAQQ 279
>gi|170767288|ref|ZP_02901741.1| endonuclease 4 [Escherichia albertii TW07627] >gi|170123622|gb|EDS92553.1| endonuclease 4 [Escherichia albertii TW07627] (285 aa)
Score = 384, Expect = 2.9e-35, Identities = 92/279 (32%), Positives = 146/279 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T+  V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++   +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTEG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKIFADFARIVGFKYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|28897272|ref|NP_796877.1| endonuclease IV [Vibrio parahaemolyticus RIMD 2210633] >gi|31076676|sp|Q87SC6|END4_VIBPA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|28805481|dbj|BAC58761.1| endonuclease IV [Vibrio parahaemolyticus RIMD 2210633] (295 aa)
Score = 384, Expect = 3.0e-35, Identities = 100/284 (35%), Positives = 155/284 (54%)
  Q:    21 MCMSKNKL---LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           M   KNK    L+G+HV   A   +  + L   E   N F +FT   + ++ K L+   I  A K   +      E+I+ H  YLINLG+P+           I E+ R NQ+   L+  HPGS L        +  IA+++N A   T  DV+  +E  AG+G+ +G  FE +++I+  V++K R+GVC+DTCH   +G D+    D ++T  EF + + + Y++ +HLNDSK E  S+ DRH ++G G++G+D     A + +   +P ILET    D  I++QEI  L
  S:     1 MTNMKNKFGNKLIGAHV--SAAGGVDQAPLRAREIGANAFALFTKNQRQWVAKPLEAKTI-SAFKANCKMLGFGAEHILPHDSYLINLGAPEAEKLDKSRAAFIDEMERCNQLGLTLLNFHPGSHLKKVSEQECLATIAESINLA-HKTVPDVVAVIENTAGQGTNLGWKFEHLAEIIEQVEDKDRVGVCIDTCHTFTAGYDLRTKEDCERTFAEFDRIVGMHYLRAMHLNDSKVEFASKVDRHHSLGKGEIGWDCFEYIAKDSRFDGIPLILETI---DPDIWQQEINTL 284
>gi|153840075|ref|ZP_01992742.1| endonuclease 4 [Vibrio parahaemolyticus AQ3810] >gi|149746333|gb|EDM57390.1| endonuclease 4 [Vibrio parahaemolyticus AQ3810] (295 aa)
Score = 383, Expect = 4.4e-35, Identities = 100/284 (35%), Positives = 155/284 (54%)
  Q:    21 MCMSKNKL---LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           M   KNK    L+G+HV   A   +  + L   E   N F +FT   + ++ K L+   I  A K   +      E+I+ H  YLINLG+P+           I E+ R NQ+   L+  HPGS L        +  IA+++N A   T  DV+  +E  AG+G+ +G  FE +++I+  V++K R+GVC+DTCH   +G D+    D ++T  EF + + + Y++ +HLNDSK E  S+ DRH ++G G++G+D     A + +   +P ILET    D  I++QEI  L
  S:     1 MTNMKNKFGNKLIGAHV--SAAGGVDQAPLRAREIGANAFALFTKNQRQWVAKPLEAKTI-SAFKANCKMLGFSAEHILPHDSYLINLGAPEVDKLDKSRAAFIDEMERCNQLGLTLLNFHPGSHLKKVSEQECLATIAESINLA-HKTVPDVVAVIENTAGQGTNLGWKFEHLAEIIEQVEDKDRVGVCIDTCHTFTAGYDLRTKEDCERTFAEFDRIVGMHYLRAMHLNDSKVEFASKVDRHHSLGKGEIGWDCFEYIAKDSRFDGIPLILETI---DPDIWQQEINTL 284
>gi|146954|gb|AAA24216.1| endonuclease IV (285 aa)
Score = 383, Expect = 4.5e-35, Identities = 92/279 (32%), Positives = 145/279 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV       L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHVSRAGG--LANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|170681734|ref|YP_001744353.1| endonuclease 4 [Escherichia coli SMS-3-5] >gi|170519452|gb|ACB17630.1| endonuclease 4 [Escherichia coli SMS-3-5] (285 aa)
Score = 382, Expect = 5.6e-35, Identities = 92/279 (32%), Positives = 148/279 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T + V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+   ++ ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKT-HGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTSAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|163803371|ref|ZP_02197247.1| endonuclease IV [Vibrio campbellii AND4] >gi|159172833|gb|EDP57675.1| endonuclease IV [Vibrio campbellii AND4] (295 aa)
Score = 382, Expect = 5.7e-35, Identities = 94/273 (34%), Positives = 153/273 (56%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
            +G+HV   A   +  + L   E   N F +FT   + ++ K L++  I  A K   +      E+I+ H  YLINLG+P+E   +      + E+ R +Q+   L+  HPGS L        +  IA+++N A +A  N VI  +E  AG+G+ +G  FE +++I++ V++K+R+GVCLDTCH   +G D+    D ++T  EF + + + Y++ +HLNDSK    SR DRH ++G G++G+      A + +  ++P ILET    D  I+ QEI
  S:    12 FIGAHV--SAAGGVDQAPLRAREIGANAFALFTKNQRQWVAKPLEEKTI-SAFKANCKMLGFGAEHILPHDSYLINLGAPEEEKLNKSRAAFVDEMGRCHQLGLTLLNFHPGSHLKKVSEQECLATIAESINLAHKAVPN-VIAVIENTAGQGTNLGWKFEHLAEIIAQVEDKERVGVCLDTCHTFTAGYDLRTEEDCERTFAEFDRIVGMHYLRAMHLNDSKVAFASRVDRHHSLGKGEIGWSCFEYIAKDPRFDSIPLILETI---DPDIWPQEI 281
>gi|110596864|ref|ZP_01385154.1| apurinic endonuclease (APN1) [Chlorobium ferrooxidans DSM 13031] >gi|110341551|gb|EAT60011.1| apurinic endonuclease (APN1) [Chlorobium ferrooxidans DSM 13031] (280 aa)
Score = 382, Expect = 6.2e-35, Identities = 90/266 (33%), Positives = 142/266 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISD---PDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKP 295
           +G+HV       +  + L+        F +FT   + +   +L+ + ID  +K   +      ++I+ H  YLINLGSP    R +  +  I E+ R   +   L+  HPGS L +      +  IA+++N+A++ T   V   +E  AG+GS +G  FE+++ I+  V++K R GVCLDTCH+  SG D+S     + T  EF + + L Y++ +HLND+   IGSR DRH +IG G +G +      +N     +P ILETP  D  P
  S:     4 VGAHVSIAGG--VENAPLQAATIGAKAFALFTKNQRQWRAPKLETSSIDAFLKNCNDGG-FKPQHILPHDSYLINLGSPDTGKRQVSRDAFIGEMQRVEALQLTLLNFHPGSHLKEISEEECLRLIAESINRALDVTKG-VTAVIENTAGQGSNLGYRFEQLASIIDQVEDKTRAGVCLDTCHLFASGYDLSSAAAAEATFCEFDRIVGLHYLRGMHLNDAMQPIGSRIDRHASIGKGTIGVEAFSYIMNNPVFEEIPLILETPDSDQWP 269
>gi|194436049|ref|ZP_03068151.1| endonuclease 4 [Escherichia coli 101-1] >gi|194424777|gb|EDX40762.1| endonuclease 4 [Escherichia coli 101-1] (285 aa)
Score = 381, Expect = 6.6e-35, Identities = 92/279 (32%), Positives = 145/279 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GS  DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVAEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSSVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|193213359|ref|YP_001999312.1| apurinic endonuclease Apn1 [Chlorobaculum parvum NCIB 8327] >gi|193086836|gb|ACF12112.1| apurinic endonuclease Apn1 [Chlorobaculum parvum NCIB 8327] (281 aa)
Score = 381, Expect = 7.0e-35, Identities = 94/282 (33%), Positives = 146/282 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +G+HV       +  + L   +     F +FT   + +    L    I EA +   E+   L ++I+ H  YLINLG+P+             E+ R   +   ++  HPGS L+    N  +  IA+++N ++ AT   V   +E  AG+GS +G  FE +++I+  V++K R+GVCLDTCH+  SG D+  P   D TL EF + + LSY++ +HLND+K ++GSR DRH  IG G +G +  V    +  +  +P ILETP               NS+ W E
  S:     4 VGAHVSIAGG--VENAPLNAQKIGAKAFAMFTRNQRQWHSAPLSTASI-EAFRRNCEEAGFLPQHILPHDSYLINLGAPEVEKLEKSRKAFTTEMQRAEALGLTMLNFHPGSHLNLVSENECLATIAESVNLSLNATAG-VTAVIENTAGQGSNLGWRFEHLARIIELVEDKSRVGVCLDTCHLFASGYDLRTPEAFDATLAEFDRVVGLSYLRGMHLNDAKQKLGSRVDRHACIGEGMIGREAFVHLMQHPAMEEIPLILETP---------------NSESWAE 270
>gi|156845448|ref|XP_001645615.1| hypothetical protein Kpol_1033p64 [Vanderwaltozyma polyspora DSM 70294] >gi|156116280|gb|EDO17757.1| hypothetical protein Kpol_1033p64 [Vanderwaltozyma polyspora DSM 70294] (363 aa)
Score = 381, Expect = 7.0e-35, Identities = 92/257 (35%), Positives = 143/257 (55%)
  Q:    55 NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           N F +F   P+ ++  +  +  +D+  +L K+ +   L +I+ H  Y INL +P         + L+ ++ R  Q+   L  +HPGS+L  D    +  +AD LNKAI+ T   V I +E MAG G+ VG N  ++ +++  +++K RIGVC+DTCH   +G DI      D+  +EF + +   Y+K IHLNDSK  + + +D H+ +G G +G +     A+N+KL N+P ILETP   D   Y  EI  L   EW E
  S:    37 NAFAMFLKSPRKWVSPQYTKEEVDKFKELCKQHDYNPLTDILPHGQYFINLANPDIEKAEKSYDSLLDDLKRCEQLGVGLYNMHPGSSLTGDHKQQLKQLADYLNKAIKET-KFVKILLENMAGTGNLVGSNLADLREVIDMIEDKSRIGVCIDTCHTFAAGYDIGSKEAFDKFWKEFDEIVGYDYLKAIHLNDSKAPLSANRDLHEKLGEGFLGLEVFRIIANNDKLYNIPIILETPQEKDDG-YGNEIKLL---EWLE 291
>gi|187730213|ref|YP_001879510.1| endonuclease 4 [Shigella boydii CDC 3083-94] >gi|187427205|gb|ACD06479.1| endonuclease 4 [Shigella boydii CDC 3083-94] (285 aa)
Score = 381, Expect = 7.9e-35, Identities = 92/279 (32%), Positives = 145/279 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H  YLINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G   +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEDNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|168229568|ref|ZP_02654626.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Kentucky str. CDC 191] >gi|168242299|ref|ZP_02667231.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Heidelberg str. SL486] >gi|194447785|ref|YP_002046257.1| endonuclease 4 [Salmonella enterica subsp. enterica serovar Heidelberg str. SL476] >gi|194472297|ref|ZP_03078281.1| endonuclease 4 [Salmonella enterica subsp. enterica serovar Kentucky str. CVM29188] >gi|194406089|gb|ACF66308.1| endonuclease 4 [Salmonella enterica subsp. enterica serovar Heidelberg str. SL476] >gi|194458661|gb|EDX47500.1| endonuclease 4 [Salmonella enterica subsp. enterica serovar Kentucky str. CVM29188] (285 aa)
Score = 380, Expect = 1.0e-34, Identities = 93/282 (32%), Positives = 147/282 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +G+HV   A   L  +     E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P         +  + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  EF K +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P ILET   D   I+ +EI  L +++  E
  S:     4 IGAHV--SAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDD-FKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDARFDGIPLILETINPD---IWAEEIAWLKAQQIAE 282
>gi|56412885|ref|YP_149960.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150] >gi|81359775|sp|Q5PE50|END4_SALPA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|56127142|gb|AAV76648.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150] (285 aa)
Score = 380, Expect = 1.0e-34, Identities = 93/282 (32%), Positives = 147/282 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +G+HV   A   L  +     E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P         +  + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  EF K +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P ILET   D   I+ +EI  L +++  E
  S:     4 IGAHV--SAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDD-FKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDARFDGIPLILETINPD---IWAEEIAWLKAQQIAE 282
>gi|16761144|ref|NP_456761.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Typhi str. CT18] >gi|29141162|ref|NP_804504.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Typhi str. Ty2] >gi|168475567|ref|ZP_02704590.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Virchow str. SL491] >gi|24636828|sp|Q8Z593|END4_SALTI Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|25289192|pir||AC0783 endonuclease IV [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18) >gi|16503442|emb|CAD02585.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Typhi] >gi|29136788|gb|AAO68353.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Typhi Ty2] (285 aa)
Score = 380, Expect = 1.0e-34, Identities = 93/282 (32%), Positives = 147/282 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +G+HV   A   L  +     E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P         +  + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  EF K +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P ILET   D   I+ +EI  L +++  E
  S:     4 IGAHV--SAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDD-FKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDARFDGIPLILETINPD---IWAEEIAWLKAQQIAE 282
>gi|193084097|gb|ACF09764.1| apurinic endonuclease Apn1 [uncultured bacterium KM3-153-F8] (280 aa)
Score = 379, Expect = 1.1e-34, Identities = 91/260 (35%), Positives = 141/260 (54%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKEL-DQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQ---TLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           LG HV       L  SV      + N F ++T  P+ +   +L + N+++   K++ E     +  +V H PYL NL SPK+   ++ +  L  E+ R N++    +V H GS L S     +N +    N A+  + N+ +I +E  AG  + VG  FEE+  I   +K+K RIG C DTCH   +G D+S       TL++F+K + + Y+KV+HLNDSK E+G+  DRH +IG G +G +   +   N  +  +P ILETP
  S:     3 LGVHVSIAGSIDL--SVDRARSLNLNTFQIYTRNPRGWKFSDLKESNILNFKSKIISEN----ISAVVCHMPYLPNLSSPKDDLHNMSIVSLASELERCNKLGIDYVVTHIGSHLGSGLEQGLNRVVKACNTAMSDSANNTMIILENTAGTKNNVGSKFEELKYIFDNIKDKSRIGFCFDTCHAFAAGYDLSSRKSVIDTLDQFNKIIGMKYLKVVHLNDSKGELGNGLDRHQHIGKGHIGEEGFRQLLKNPDIKQLPLILETP 260
>gi|167557890|ref|ZP_02350902.1| hypothetical protein Sententeri_13758 [Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853] (285 aa)
Score = 379, Expect = 1.2e-34, Identities = 93/282 (32%), Positives = 147/282 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +G+HV   A   L  +     E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P         +  + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  EF K +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P ILET   D   I+ +EI  L +++  E
  S:     4 IGAHV--SAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDD-FKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFSEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDGRFDGIPLILETINPD---IWAEEIAWLKAQQIAE 282
>gi|160285665|pdb|2NQ9|A Chain A, High Resolution Crystal Structure Of Escherichia Coli Endonuclease Iv (Endo Iv) Y72a Mutant Bound To Damaged Dna (285 aa)
Score = 379, Expect = 1.3e-34, Identities = 92/279 (32%), Positives = 145/279 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  + +   E D   F +FT   + +    L    IDE  K   EK       I+ H   LINLG P         +  I E+ R  Q+   L+  HPGS L        +  IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  +F++ +   Y++ +HLND+K+  GSR DRH ++G G +G D       +++   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDE-FKAACEKYHYTSAQILPHDSALINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPD---IWAEEIAWLKAQQ 279
>gi|167546766|ref|ZP_02342330.1| hypothetical protein Sentent_25975 [Salmonella enterica subsp. enterica serovar Saintpaul str. SARA23] (285 aa)
Score = 378, Expect = 1.5e-34, Identities = 93/282 (32%), Positives = 147/282 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +G+HV   A   L  +     E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P         +  + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  EF K +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P ILET   D   I+ +EI  L +++  E
  S:     4 IGAHV--SAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDD-FKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFTEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDGRFDGIPLILETINPD---IWAEEIAWLKAQQIAE 282
>gi|16765533|ref|NP_461148.1| endonuclease IV [Salmonella typhimurium LT2] >gi|161613098|ref|YP_001587062.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7] >gi|167551168|ref|ZP_02344923.1| hypothetical protein Sentente_11827 [Salmonella enterica subsp. enterica serovar Saintpaul str. SARA29] >gi|167991139|ref|ZP_02572238.1| hypothetical protein Sententer_01000005_0100006819 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:- str. CVM23701] >gi|168466107|ref|ZP_02699977.1| endonuclease 4 [Salmonella enterica subsp. enterica serovar Newport str. SL317] >gi|189037128|sp|A9N6I5|END4_SALPB Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|24636835|sp|Q8ZNK6|END4_SALTY Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|16420741|gb|AAL21107.1| endonuclease IV [Salmonella typhimurium LT2] >gi|161362462|gb|ABX66230.1| hypothetical protein SPAB_00806 [Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7] >gi|195631363|gb|EDX49923.1| endonuclease 4 [Salmonella enterica subsp. enterica serovar Newport str. SL317] (285 aa)
Score = 378, Expect = 1.5e-34, Identities = 93/282 (32%), Positives = 147/282 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +G+HV   A   L  +     E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P         +  + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  EF K +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P ILET   D   I+ +EI  L +++  E
  S:     4 IGAHV--SAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDD-FKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDGRFDGIPLILETINPD---IWAEEIAWLKAQQIAE 282
>gi|139437315|ref|ZP_01771475.1| Hypothetical protein COLAER_00454 [Collinsella aerofaciens ATCC 25986] >gi|133776962|gb|EBA40782.1| Hypothetical protein COLAER_00454 [Collinsella aerofaciens ATCC 25986] (288 aa)
Score = 378, Expect = 1.5e-34, Identities = 93/262 (35%), Positives = 141/262 (53%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI-EATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKK-----RIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKV-------GFDYLVKWAHNEKLANVPKILETP 289
           L +G H+        +G     L    N F  FT  P+    K+LD + +    +LM + +      +V HAPY  N  S KE  R   L  +  ++ R   +       HPG+ +    +  I  I D L + + E     V++  ETMAGKG+EVG +FEE++ I+ GV +K+     ++GVCLDTCH++D+G DI  D D  L+EF + + +  ++ +H+NDSKN  G+ KDRH+ IG G +       G   +     N +L  +P ILETP
  S:     2 LTIGCHLSTTKGYRAMGET--ALSIGANTFAFFTRNPRGGKAKDLDMDDVAALRELMAQND---FGPLVAHAPYTYNPCSAKERAREFALEAMAEDLRRMEALPGNYYNFHPGAHVGQGSDAGIQMIVDTLCQVMFEGQQTTVLL--ETMAGKGTEVGRSFEELALIIEGVADKRPELSAKLGVCLDTCHVNDAGYDIVHDLDGVLDEFDRVVGIERLRAVHINDSKNPCGAHKDRHECIGKGYLGSEEFGGGMQVMQNIVSNGRLRALPFILETP 270
>gi|189439349|ref|YP_001954430.1| Endonuclease IV [Bifidobacterium longum DJO10A] >gi|189427784|gb|ACD97932.1| Endonuclease IV [Bifidobacterium longum DJO10A] (283 aa)
Score = 378, Expect = 1.7e-34, Identities = 79/210 (37%), Positives = 125/210 (59%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSK----LIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID-ISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           +VVHAPY+ NL    E+ R+  +  L  +I     I        I +HPG+ +          I++ LN+  E T   V++ +ETMAGKG+E G NFEE++ I++GV+NK  +GV  DTCH+ D+G D + D D  + +  + + L+ +K IH+NDS+  +GS KDRH NIG G++G  +  +  ++  +A +P ILET  ++  P   ++ I L
  S:    66 LVVHAPYVYNLAGKDEAKRTFAIEALAEDIELLTAIREAGQEVYINIHPGAHVGQGTETGCRLISEGLNQVFERT-TGVMVLLETMAGKGTECGRNFEELATIMNGVENKANVGVTFDTCHVLDAGYDLVHDYDGVMRQLDEAIGLAEVKAIHVNDSQFGLGSHKDRHANIGQGQLGIPFFTRLVNDPTMAKLPMILET--KEQTPTTHRDEIAL 277
>gi|46191217|ref|ZP_00206713.1| COG0648: Endonuclease IV [Bifidobacterium longum DJO10A] (282 aa)
Score = 378, Expect = 1.7e-34, Identities = 79/210 (37%), Positives = 125/210 (59%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSK----LIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID-ISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           +VVHAPY+ NL    E+ R+  +  L  +I     I        I +HPG+ +          I++ LN+  E T   V++ +ETMAGKG+E G NFEE++ I++GV+NK  +GV  DTCH+ D+G D + D D  + +  + + L+ +K IH+NDS+  +GS KDRH NIG G++G  +  +  ++  +A +P ILET  ++  P   ++ I L
  S:    65 LVVHAPYVYNLAGKDEAKRTFAIEALAEDIELLTAIREAGQEVYINIHPGAHVGQGTETGCRLISEGLNQVFERT-TGVMVLLETMAGKGTECGRNFEELATIMNGVENKANVGVTFDTCHVLDAGYDLVHDYDGVMRQLDEAIGLAEVKAIHVNDSQFGLGSHKDRHANIGQGQLGIPFFTRLVNDPTMAKLPMILET--KEQTPTTHRDEIAL 276
>gi|163728784|ref|ZP_02136267.1| endonuclease IV [Vibrio fischeri MJ11] >gi|161398263|gb|EDQ22549.1| endonuclease IV [Vibrio fischeri MJ11] (282 aa)
Score = 378, Expect = 1.7e-34, Identities = 84/253 (33%), Positives = 145/253 (57%)
  Q:    54 GNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
            N F +FT   + ++ K L + +I +  K   ++     + I+ H  YLINLG+P+           I E+ R +Q+   L+  HPGS L     +  ++ IA+++N A +A   DV+  +E  AG+G+ +G  FE++++I+  V++K R+G+C+DTCH   +G D+S     + T  EF + +   Y++ +H+ND+K E+GSR DRH ++G G +G+D       +++  N+P +LET    D  I+K EI  L +
  S:    26 ANAFALFTKNQRQWVAKPLTKKIISD-FKANCKRFGFSSDQILPHDSYLINLGAPETEKLEKSRAAFIDEMERCHQLGLTLLNFHPGSHLKKISEDECLSLIAESINLAHQAVP-DVVAVIENTAGQGTNLGWKFEQLAQIIEQVEDKSRVGICIDTCHTFAAGYDLSSKEACEHTFAEFERIVGFQYLRGMHINDAKIELGSRVDRHHSLGQGTIGWDCFEYIMQDDRFNNIPLVLETI---DPDIWKDEIAQLRT 277
>gi|50548559|ref|XP_501749.1| hypothetical protein [Yarrowia lipolytica] >gi|49647616|emb|CAG82059.1| unnamed protein product [Yarrowia lipolytica CLIB122] (386 aa)
Score = 378, Expect = 1.8e-34, Identities = 92/264 (34%), Positives = 149/264 (56%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           +G+HV   AK  +  +V  +    GN F +F    + +  ++ D++ +DE   L KE       +I+ H  YLINL SP  +T    L   I ++ R   +      LHPG+ +  D+   I  +A N+++ +EAT N V + +E MAG+G+ +G + ++++ I+  VKNK+R+GVC+DTCH   +G D+ D    ++  ++F K +   Y+  IHLNDSK  + S +D H+NIGYG +G +      +  +L  +P ILETP  DD
  S:    10 VGAHVS-TAKG-VQNAVTNSANMSGNSFALFLKSQRQWTGRKYDKSEVDEFHDLCKEHKYSGKTDILPHGSYLINLASPDANTAYNSLKGFIDDLQRCELLGISKYNLHPGATVGYDKKKCIERLAANIDRGLEAT-NFVQVVLENMAGQGTTLG-DLDDLAAIIDLVKNKERVGVCIDTCHTFAAGYDLRDEKSFNKFWKQFDKLIGYKYLAGIHLNDSKTPLNSNRDLHENIGYGFLGLEAFRLVMNKPELEGLPLILETPGEDD 272
>gi|194442304|ref|YP_002041476.1| endonuclease 4 [Salmonella enterica subsp. enterica serovar Newport str. SL254] >gi|194400967|gb|ACF61189.1| endonuclease 4 [Salmonella enterica subsp. enterica serovar Newport str. SL254] (285 aa)
Score = 377, Expect = 1.8e-34, Identities = 93/282 (32%), Positives = 147/282 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +G+HV   A   L  +     E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P         +  + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  EF K +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P ILET   D   I+ +EI  L +++  E
  S:     4 IGAHV--SAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDD-FKIACEKYLFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDGRFDGIPLILETINPD---IWAEEIAWLKAQQIAE 282
>gi|193810086|emb|CAQ41280.1| apurinic/apyrimidinic endonuclease Apn1,putative [Plasmodium knowlesi strain H] (479 aa)
Score = 377, Expect = 1.9e-34, Identities = 99/272 (36%), Positives = 145/272 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP-YRDDKPIYKQEI 301
           LG+H+   A   +  S        G  F +F    + +    L    I +  K  K  N L    I+ H  YLINL +P +  R       + ++ R  Q+  +L   HPGS          I +I+D +N+  + T N VII +E  AG+ + VG  FE++  I+S +++K RIGVCLDTCH   +G DI    D D  +++F + +D  Y+K IHLNDSK+++GS  DRH+NIG GK+  D       ++   N+P ILETP   DD+ +YK EI
  S:   192 LGAHI--SAAGGVQNSPTNCFNVAGQAFALFLKNQRKWDSPPLSSENIKQFEKNCKAYN-LDTRFILPHGSYLINLANPDKEKREKSYLSFLDDVKRCEQLKVQLYNFHPGSTTGLCSLEEGIKNISDCINRVHKETSN-VIIVLENSAGQKNSVGSKFEDLKNIISQIEDKSRIGVCLDTCHTFAAGYDIRSYEDFDLVMKKFDEIVDAKYLKAIHLNDSKSDLGSGLDRHENIGKGKLTMDTFKYIMTSKYFKNIPIILETPDVTDDESVYKYEI 464
>gi|160903245|ref|YP_001568826.1| apurinic endonuclease Apn1 [Petrotoga mobilis SJ95] >gi|189037125|sp|A9BJ15|END4_PETMO Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|160360889|gb|ABX32503.1| apurinic endonuclease Apn1 [Petrotoga mobilis SJ95] (287 aa)
Score = 377, Expect = 2.0e-34, Identities = 91/254 (35%), Positives = 144/254 (56%)
  Q:    48 ETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI-EATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQT---LEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           +T    GN F +FT  P+ +      +N ++     M E N +  E+++VH+ YLINL SPK+  R   +  +I EI  T+Q+       HPGS L       IN I + L+    E  +  V I +E +A KGS +G + E++ +I++    K+R+G+  DTCH  DS  DI   ++    L+E  KY+ L+ +K+IHLNDSK ++G+ KDRH+ IG G +G +    +   ++++ +P ILETP   D P + Q+I
  S:    20 DTANIGGNTFQIFTSSPRVWKVNPPKENDVEGFKNAMTEFN-INFEDVLVHSSYLINLASPKDDIREKSITAMIEEIKATDQLGILHYNFHPGSHLGEGEEFGINKILEGLDIIFKEVQNTKVTILLENVAQKGSNIGYSMEQLGRIINKSPWKERLGITYDTCHGFDSNYDIRKKEEVQRLLDEIDKYIGLNKLKMIHLNDSKYDVGAAKDRHEFIGKGYIGREGFKTFLSFDEISKLPLILETP--GDDPEHSQDI 274
>gi|156740568|ref|YP_001430697.1| apurinic endonuclease Apn1 [Roseiflexus castenholzii DSM 13941] >gi|156231896|gb|ABU56679.1| apurinic endonuclease Apn1 [Roseiflexus castenholzii DSM 13941] (289 aa)
Score = 377, Expect = 2.1e-34, Identities = 73/199 (36%), Positives = 119/199 (59%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND-VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQ---TLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           ++VH  YLINL +P +      L     E+ R   +    +V HPG+ + S     +  +A  L++  E+   D V + +ET AG+GS +G  FEE+++I+   +   R+GVC+DTCH+  +G DI  P+Q   T+EE  + + ++ +K  H+NDS+ E+GSR DRH +IG G +G +      ++E+ A++P +LETP  DD
  S:    66 VLVHDSYLINLAAPGDELWHKSLEAFREELERCALLGVPYLVTHPGAHVGSGEEAGMRRVAAALDRVFESGAGDGVTVLLETTAGQGSSLGRRFEELARIIEYSRYPNRLGVCVDTCHIFAAGYDIRTPEQYAATIEELDRVIGIARVKAFHMNDSQKELGSRVDRHTHIGEGCIGLEGFRALVNDERFADLPMVLETPKGDD 268
>gi|77958495|ref|ZP_00822527.1| COG0648: Endonuclease IV [Yersinia bercovieri ATCC 43970] (281 aa)
Score = 377, Expect = 2.1e-34, Identities = 96/279 (34%), Positives = 156/279 (55%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL---DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
            +G+HV   A   +  +V+   E +   F +FT   + +    L +++I E  KL  E+       I+ H  YLINLG P            I E+ R  Q+   L+  HPGS L   D D+ +A   IA+++N A++A++  V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+   +D + T ++    +   Y++ +HLND+K+E  SR DRH ++G G +G   F Y+++   + +  N+P ILET   D   I+ +EI  L S+
  S:     3 FVGAHV--SAAGGVDQAVIRAHELEATAFALFTKNQRQWRAAPLAEDVI-ERFKLACEQYGYTSAQILPHDSYLINLGHPVIEALEKSREAFIDEMARCQQLGLSLLNFHPGSHLLQIDEDKCLA--RIAESINIALDASEG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTEADCEHTFKQLGDIVGFQYLRGMHLNDAKSEFNSRVDRHHSLGEGNIGKTVFSYIMR---DARFDNIPLILETVNMD---IWAEEIAWLKSQ 278
>gi|16121588|ref|NP_404901.1| endonuclease IV [Yersinia pestis CO92] >gi|51595678|ref|YP_069869.1| endonuclease IV [Yersinia pseudotuberculosis IP 32953] >gi|108807019|ref|YP_650935.1| endonuclease IV [Yersinia pestis Antiqua] >gi|108812834|ref|YP_648601.1| endonuclease IV [Yersinia pestis Nepal516] >gi|145599663|ref|YP_001163739.1| endonuclease IV [Yersinia pestis Pestoides F] >gi|149366715|ref|ZP_01888749.1| endonuclease IV [Yersinia pestis CA88-4125] >gi|162418658|ref|YP_001606041.1| endonuclease IV [Yersinia pestis Angola] >gi|165924692|ref|ZP_02220524.1| endonuclease 4 [Yersinia pestis biovar Orientalis str. F1991016] >gi|165936345|ref|ZP_02224914.1| endonuclease 4 [Yersinia pestis biovar Orientalis str. IP275] >gi|166009890|ref|ZP_02230788.1| endonuclease 4 [Yersinia pestis biovar Antiqua str. E1979001] >gi|166211711|ref|ZP_02237746.1| endonuclease 4 [Yersinia pestis biovar Antiqua str. B42003004] >gi|167400373|ref|ZP_02305886.1| endonuclease 4 [Yersinia pestis biovar Antiqua str. UG05-0454] >gi|167419616|ref|ZP_02311369.1| endonuclease 4 [Yersinia pestis biovar Orientalis str. MG05-1020] >gi|167423873|ref|ZP_02315626.1| endonuclease 4 [Yersinia pestis biovar Mediaevalis str. K1973002] >gi|167469593|ref|ZP_02334297.1| endonuclease IV [Yersinia pestis FV-1] >gi|170024981|ref|YP_001721486.1| apurinic endonuclease Apn1 [Yersinia pseudotuberculosis YPIII] >gi|186894749|ref|YP_001871861.1| apurinic endonuclease Apn1 [Yersinia pseudotuberculosis PB1/+] >gi|123073265|sp|Q1CG79|END4_YERPN Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|123372568|sp|Q1C982|END4_YERPA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|166224297|sp|A4TNA4|END4_YERPP Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|24636834|sp|Q8ZGJ1|END4_YERPE Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|59797711|sp|Q66CR5|END4_YERPS Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|51588960|emb|CAH20577.1| endonuclease IV [Yersinia pseudotuberculosis IP 32953] >gi|108776482|gb|ABG19001.1| Endonuclease IV [Yersinia pestis Nepal516] >gi|108778932|gb|ABG12990.1| Endonuclease IV [Yersinia pestis Antiqua] >gi|115347067|emb|CAL19959.1| endonuclease IV [Yersinia pestis CO92] >gi|145211359|gb|ABP40766.1| Endonuclease IV [Yersinia pestis Pestoides F] >gi|149291089|gb|EDM41164.1| endonuclease IV [Yersinia pestis CA88-4125] >gi|162351473|gb|ABX85421.1| endonuclease 4 [Yersinia pestis Angola] >gi|165915959|gb|EDR34567.1| endonuclease 4 [Yersinia pestis biovar Orientalis str. IP275] >gi|165923752|gb|EDR40884.1| endonuclease 4 [Yersinia pestis biovar Orientalis str. F1991016] >gi|165991286|gb|EDR43587.1| endonuclease 4 [Yersinia pestis biovar Antiqua str. E1979001] >gi|166207482|gb|EDR51962.1| endonuclease 4 [Yersinia pestis biovar Antiqua str. B42003004] >gi|166962357|gb|EDR58378.1| endonuclease 4 [Yersinia pestis biovar Orientalis str. MG05-1020] >gi|167050322|gb|EDR61730.1| endonuclease 4 [Yersinia pestis biovar Antiqua str. UG05-0454] >gi|167056722|gb|EDR66485.1| endonuclease 4 [Yersinia pestis biovar Mediaevalis str. K1973002] >gi|169751515|gb|ACA69033.1| apurinic endonuclease Apn1 [Yersinia pseudotuberculosis YPIII] >gi|186697775|gb|ACC88404.1| apurinic endonuclease Apn1 [Yersinia pseudotuberculosis PB1/+] (285 aa)
Score = 377, Expect = 2.2e-34, Identities = 96/279 (34%), Positives = 151/279 (54%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGS-ALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
            +G+HV   A   +  +V+   E +   F +FT   + +    L +++I E  KL  EK       I+ H  YLINLG P            I E+ R  Q+   L+  HPGS  L  D +  +  IA+++N A++AT+  V   +E  AG+GS +G  FE ++ I+  V++K R+GVC+DTCH   +G D+    D + T     K +   Y++ +HLND+K+E  SR DRH ++G G +G   F Y+++   + +  N+P ILET   D   I+ +EI  L S+
  S:     3 FVGAHV--SAAGGVDQAVIRAHELEATAFALFTKNQRQWRAAPLAEDVI-EKFKLACEKYGYTSAQILPHDSYLINLGHPVTEALEKSREAFIDELVRCQQLGLSLLNFHPGSHLLQIDEDQCLARIAESINIALDATEG-VTAVIENTAGQGSNLGFKFEHLAAIIERVEDKSRVGVCIDTCHAFAAGYDLRTEEDCEHTFAALGKIVGFQYLRGMHLNDAKSEFNSRVDRHHSLGEGNIGKTVFSYIMR---DSRFDNIPLILETVNMD---IWAEEIAWLKSQ 278
>gi|23465335|ref|NP_695938.1| endonuclease IV [Bifidobacterium longum NCC2705] >gi|39931160|sp|Q8G689|END4_BIFLO Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|23325976|gb|AAN24574.1| probable endonuclease IV [Bifidobacterium longum NCC2705] (283 aa)
Score = 376, Expect = 2.4e-34, Identities = 78/210 (37%), Positives = 126/210 (60%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSK----LIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           +VVHAPY+ NL    E+ R+  +  L  +I     I +      I +HPG+ +          I++ LN+  E  D  V++ +ETMAGKG+E G NF+E++ I+ GV+NK  +GV  DTCH+ D+G D+ +D D  + +  + + L+ +K IH+NDS+  +GS KDRH NIG G++G  +  +  ++  +A +P ILET  ++  P   ++ I L
  S:    66 LVVHAPYVYNLAGKDEAKRAFAIEALAEDIELLTAIRAAGQEVYINIHPGAHVGQGAETGCRLISEGLNQVFERADG-VMVLLETMAGKGTECGRNFDELATIMDGVENKANVGVTFDTCHVLDAGYDLENDYDGVMRQLDEAIGLARVKAIHVNDSQFGLGSHKDRHANIGEGQLGIPFFTRLVNDPTMAKLPMILET--KEQTPTTHRDEIAL 277
>gi|153949100|ref|YP_001401640.1| endonuclease IV [Yersinia pseudotuberculosis IP 31758] >gi|166920087|sp|A7FK62|END4_YERP3 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|152960595|gb|ABS48056.1| endonuclease 4 [Yersinia pseudotuberculosis IP 31758] (285 aa)
Score = 376, Expect = 2.4e-34, Identities = 96/279 (34%), Positives = 151/279 (54%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGS-ALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
            +G+HV   A   +  +V+   E +   F +FT   + +    L +++I E  KL  EK       I+ H  YLINLG P            I E+ R  Q+   L+  HPGS  L  D +  +  IA+++N A++AT+  V   +E  AG+GS +G  FE ++ I+  V++K R+GVC+DTCH   +G D+    D + T     K +   Y++ +HLND+K+E  SR DRH ++G G +G   F Y+++   + +  N+P ILET   D   I+ +EI  L S+
  S:     3 FVGAHV--SAAGGVDQAVIRAHELEATAFALFTKNQRQWRAAPLAEDVI-EKFKLTCEKYGYTSAQILPHDSYLINLGHPVTEALEKSREAFIDELVRCQQLGLSLLNFHPGSHLLQIDEDQCLARIAESINIALDATEG-VTAVIENTAGQGSNLGFKFEHLAAIIEKVEDKSRVGVCIDTCHAFAAGYDLRTEEDCEHTFAALGKIVGFQYLRGMHLNDAKSEFNSRVDRHHSLGEGNIGKTVFSYIMR---DSRFDNIPLILETVNMD---IWAEEIAWLKSQ 278
>gi|22126756|ref|NP_670179.1| endonuclease IV [Yersinia pestis KIM] >gi|45441113|ref|NP_992652.1| endonuclease IV [Yersinia pestis biovar Microtus str. 91001] >gi|21959779|gb|AAM86430.1|AE013890_5 endonuclease IV [Yersinia pestis KIM] >gi|45435972|gb|AAS61529.1| endonuclease IV [Yersinia pestis biovar Microtus str. 91001] (294 aa)
Score = 376, Expect = 2.5e-34, Identities = 96/279 (34%), Positives = 151/279 (54%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGS-ALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
            +G+HV   A   +  +V+   E +   F +FT   + +    L +++I E  KL  EK       I+ H  YLINLG P            I E+ R  Q+   L+  HPGS  L  D +  +  IA+++N A++AT+  V   +E  AG+GS +G  FE ++ I+  V++K R+GVC+DTCH   +G D+    D + T     K +   Y++ +HLND+K+E  SR DRH ++G G +G   F Y+++   + +  N+P ILET   D   I+ +EI  L S+
  S:    12 FVGAHV--SAAGGVDQAVIRAHELEATAFALFTKNQRQWRAAPLAEDVI-EKFKLACEKYGYTSAQILPHDSYLINLGHPVTEALEKSREAFIDELVRCQQLGLSLLNFHPGSHLLQIDEDQCLARIAESINIALDATEG-VTAVIENTAGQGSNLGFKFEHLAAIIERVEDKSRVGVCIDTCHAFAAGYDLRTEEDCEHTFAALGKIVGFQYLRGMHLNDAKSEFNSRVDRHHSLGEGNIGKTVFSYIMR---DSRFDNIPLILETVNMD---IWAEEIAWLKSQ 287
>gi|62180789|ref|YP_217206.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67] >gi|75482226|sp|Q57MD6|END4_SALCH Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|62128422|gb|AAX66125.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67] (285 aa)
Score = 376, Expect = 2.5e-34, Identities = 93/282 (32%), Positives = 147/282 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +G+HV   A   L  +     E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P         +  + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  EF K +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P ILET   D   I+ +EI  L +++  E
  S:     4 IGAHV--SAAGGLANAPARAAEIVATAFALFTKNQRQWRAAPLTPQVIDD-FKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDGRFDGIPLILETINPD---IWAEEIAWLKAQQIAE 282
>gi|193084075|gb|ACF09745.1| endonuclease IV [uncultured bacterium AD-40-D7] (287 aa)
Score = 376, Expect = 2.7e-34, Identities = 90/260 (34%), Positives = 146/260 (56%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL---------DSDRNVAINHIADNLNKAIEATDN-DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           LG+HV       L  ++L  LE + + F +F+   + ++ K L    ++     + E +   L  +++H  YLIN+GSP E+         + E +R   +    +  HPGS              RN A+  IA+++NK +E T      + +E  AG+G+ VGI FEE+  I+  + +KKR+GVC+DT H   SG D  +D DQ  ++F + + + Y+  +HLNDSK+++GSR DRHDNIG GK+G +    +   ++L ++   LETP
  S:     3 LGAHVSVAGG--LQNAILWALEIEADTFQMFSKNQRQWIAKPLTDKEVEAFKTPLAETD---LGPLMIHDSYLINMGSPDETKGKRAQVAFLEEYHRCEALGVAYLNFHPGSHTHPKKDMRDDKQTRNEALERIANHMNKTLEETKGYGSKLVIENAAGQGTNVGIKFEEIKHIIDHINDKKRVGVCIDTQHAWASGYDWRNDFDQIWDDFEEIVGMEYLVALHLNDSKSDLGSRVDRHDNIGVGKLGKNTFKSFMQEKRLEHLAGYLETP 268
>gi|15618642|ref|NP_224928.1| endonuclease IV [Chlamydophila pneumoniae CWL029] >gi|15836264|ref|NP_300788.1| endonuclease IV [Chlamydophila pneumoniae J138] >gi|16752309|ref|NP_444566.1| endonuclease IV [Chlamydophila pneumoniae AR39] >gi|33242091|ref|NP_877032.1| endonuclease IV [Chlamydophila pneumoniae TW-183] >gi|8928115|sp|Q9Z7H3|END4_CHLPN Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|4377037|gb|AAD18871.1| Endonuclease IV [Chlamydophila pneumoniae CWL029] >gi|7188953|gb|AAF37910.1| endonuclease IV [Chlamydophila pneumoniae AR39] >gi|8979104|dbj|BAA98939.1| endonuclease IV [Chlamydophila pneumoniae J138] >gi|33236601|gb|AAP98689.1| endonuclease IV [Chlamydophila pneumoniae TW-183] (293 aa)
Score = 376, Expect = 2.7e-34, Identities = 90/261 (34%), Positives = 148/261 (56%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPK----ESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND--VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           LLG+H        L  ++ E  +   +   +FT   + + R+ L + +I++    +KE +   L  I+ HA YLIN G+P     E +R +G+ Q   EI     +    +  HPG+AL S +   +N I  + +++    D+   +++ +ET AG+G+ +G NFEE+  +V  +KN+  IGVC+DTCH+  +G DI+ P   +  L EF +Y+ LSY++  HLNDS   +G+ KDRH  +G G +G +       +E+   +PK LETP
  S:    11 LLGAHT--STAGGLKNAIYEGRDIGASTVQIFTANQRQWQRRALKEEVIEDFKAALKETD---LSYIMSHAGYLINPGAPDPVILEKSR-IGIYQ---EILDCITLGISFVNFHPGAALKSSKEDCMNKIVSSFSQSAPLFDSSPPLVVLLETTAGQGTLIGSNFEELGYLVQNLKNQIPIGVCVDTCHIFAAGYDITSPQGWEDVLNEFDEYVGLSYLRAFHLNDSMFPLGANKDRHAPLGEGYIGKESFKFLMTDERTRKIPKYLETP 271
>gi|160941473|ref|ZP_02088808.1| hypothetical protein CLOBOL_06364 [Clostridium bolteae ATCC BAA-613] >gi|158435619|gb|EDP13386.1| hypothetical protein CLOBOL_06364 [Clostridium bolteae ATCC BAA-613] (260 aa)
Score = 376, Expect = 2.8e-34, Identities = 90/249 (36%), Positives = 131/249 (52%)
  Q:    53 DGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP-DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           + N F  FT  P+    K +D+N   +    + E   L +  I+ HAPY +N  S     R+     +  ++ R       +   HPGS +     + I  IA+ LN+ +       ++ +ETMAGKGSEVG  FEE+ +I+  V+ K  +GVCLDTCH+ D G DI +  D  L EF   + L  +K IHLNDS+N IG+ KDRH  +G G +G D   +   + +L ++P  LETP  +D   Y  EI
  S:     9 NANTFQFFTRNPRGGNAKAIDEN---DVKVFLTEVQSLDITPILAHAPYTLNACSADPKLRNFAKRTMADDLVRMEYTPGNMYNFHPGSHVKQGTEIGIQFIAEMLNEILSPAQTTTVL-LETMAGKGSEVGGAFEELRQILDLVELKSHMGVCLDTCHIWDGGYDIVNHLDDILTEFDNKIGLKCLKAIHLNDSQNPIGAHKDRHAKLGEGYIGLDTFKRIVTHPELRHLPFFLETP--NDLDGYAHEI 252
>gi|167628249|ref|YP_001678748.1| AP endonuclease [Heliobacterium modesticaldum Ice1] >gi|167590989|gb|ABZ82737.1| ap endonuclease, family 2 [Heliobacterium modesticaldum Ice1] (276 aa)
Score = 376, Expect = 3.0e-34, Identities = 95/279 (34%), Positives = 147/279 (52%)
  Q:    28 LLLGSHV----GFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           + LG+H+    GF++      +V E L      F  FT  P+    K LD + I  ++ L +E        +V HAPY INL +PKE T +     L  +I R        +V+HPGS +       I  I   LN+ +   D  V++ +E M+G G+EVG  FEE+  I+ G++  + +GV LD+CH+  +G D+ SD    L+ F + + L  +K +H+NDS+  +GS KDRH  +G G +G D L    ++  L  +P  LETP   +   Y++EI  + S
  S:     1 MYLGAHLSISKGFES------AVREALSIGATTFQFFTRNPRGGAAKALDPDDIARSIWLREEHG---FGPLVAHAPYTINLAAPKEETWAFAKMTLAADIVRMATAQVPYMVVHPGSHVGQGIEAGIERITQALNEILRP-DQGVMVLLEGMSGAGTEVGGRFEELRAIIDGLQVPEVVGVNLDSCHLFGAGYDVKSDFAAVLDAFDRIIGLERLKAMHINDSQQPLGSHKDRHALLGQGLIGSDALAALLNHPALVGLPLNLETP--GEIADYRREIAWMRS 272
>gi|47226126|emb|CAG04500.1| unnamed protein product [Tetraodon nigroviridis] (319 aa)
Score = 375, Expect = 3.6e-34, Identities = 89/267 (33%), Positives = 140/267 (52%)
  Q:    25 KNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR 291
           + K  +G+HV  +   +   +V    E  GNCF +F G  + + R  +D        +L +  + +   +IV H PYL+N GSPK          L+ E++R + +   L   HPGS+L        +  +A  +N A       V+  +E M G+G+ VG  F E+  I+  V+++ R+GVCLDTCH   +G D++        L+EF + + L Y+K +HLNDSK ++G   DRH++IG G +G        +  +L N+P ILETP R
  S:    34 RRKKYIGAHVSIQGGIW--KAVEACTELGGNCFALFLGSQRTWKRSPMDHGAAARFQEL-RSLHGIDPAHIVPHGPYLMNCGSPKTDVYEKSQTLLVDELSRCSLLGLTLYNFHPGSSLGLITTQQCLGKVAGAINHAHRQVPA-VVTVLENMCGQGATVGGRFSELRGIIDKVRDQSRVGVCLDTCHAFAAGYDLAAEGGVRAMLDEFDQEVGLHYLKAVHLNDSKGQLGCNLDRHEDIGKGCIGISAFQDVVNEPRLNNIPLILETPGR 300
>gi|194306042|dbj|BAG55476.1| putative endonuclease [uncultured bacterium] (290 aa)
Score = 375, Expect = 3.6e-34, Identities = 84/247 (34%), Positives = 135/247 (54%)
  Q:    58 MVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIE---ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR---DDKPIYKQEIINL 304
           +VFT   + +  K L +  ID   +   E + +  + + VHA YLIN+ SPK+         L VE+ R   +    I  HPGS + SD    +  I   + + ++    T  +  +C+ETMAG+G+ +G  FE+++ ++ G+    R+G+C DTCH+  +G DI  P+    T++ F   + L  IKV H NDSK E+G RKDRH +IG G +G +    + ++ + AN    +ETP     DD    + + +NL
  S:    29 LVFTKSNRQWKAKPLTEKDIDLYQQARAEYSDI--DPVAVHASYLINIASPKDDLWEKSYQALKVEVERAGALDIPFITFHPGSFVKSDAESGLARIITGVKRLLDETAVTAPNTTVCLETMAGQGTNLGYMFEQLATLLDGIGRGPRLGICFDTCHVFAAGYDIRTPEAYAATMQAFDNVIGLDQIKVFHFNDSKFELGQRKDRHAHIGDGFIGAEGFANFMNDPRWANHAAHIETPKTEKDDDGSEIEMDPVNL 282
>gi|150004972|ref|YP_001299716.1| endonuclease IV [Bacteroides vulgatus ATCC 8482] >gi|166224273|sp|A6L330|END4_BACV8 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|149933396|gb|ABR40094.1| endonuclease IV [Bacteroides vulgatus ATCC 8482] (278 aa)
Score = 375, Expect = 3.7e-34, Identities = 96/279 (34%), Positives = 150/279 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKE---KNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV       +  + +  L    + F +FT   + ++ K L      E+V L KE   K       ++ H  YLINLG P E          + E+ R   +  K++  HPGS L+       ++ IA+++N  ++ T   V   +E  AG+GS VG  F  +  I+  V++K R+GVCLDTCH + +G DI ++ D+   EF + +  +Y+  IHLNDSK  +GSR DRHD+IG G +G D+  ++  + +  ++P ILETP   D  I++ EI  L S E
  S:     4 IGAHVSVSGGVEM--APVNALGIGADAFALFTKNQRQWVAKPLSV----ESVTLFKENCEKEGFDARYVLPHDSYLINLGHPDEEGLEKSRAAFLDEMQRCELLGLKMLNFHPGSHLNKISIEKCLDRIAESVNMTLDKT-TGVTAVIENTAGQGSNVGNEFWHLRYIIDKVEDKSRVGVCLDTCHTYTAGYDIVNEYDRVFTEFDEVVGRNYLCAIHLNDSKKPLGSRVDRHDSIGKGLIGIDFFRRFMQDSRFDDMPVILETP---DDTIWRDEIKMLRSFE 277
>gi|148654781|ref|YP_001274986.1| apurinic endonuclease Apn1 [Roseiflexus sp. RS-1] >gi|148566891|gb|ABQ89036.1| Endonuclease IV [Roseiflexus sp. RS-1] (293 aa)
Score = 375, Expect = 3.9e-34, Identities = 79/218 (36%), Positives = 127/218 (58%)
  Q:    76 LIDEAVKLMKEKN-----PLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIE-ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQ---TLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           L DE +   KE       P+    ++VH  YLINL +P +      +     E+ R   +    +V HPG+ + S  +  +  +A  L+   E     DVI+ +ET AG+GS +G  FEE+++I+   ++ +R+GVC+DTCH+  +G DI  P+    T+EE  + + ++ +K  HLNDS+ E+GSR DRH +IG G +G +      ++E+ A +P +LETP  DD
  S:    46 LTDEEIARFKEAQVTEGVPV----VMVHDSYLINLAAPGDELWHKSIAAFREELERCALLGIPCLVTHPGAHVGSGEDAGLRRVAAALDLVFETGVGRDVIVLLETTAGQGSSLGRRFEELARIIEYSRHPERLGVCVDTCHIFAAGYDIRTPESYAATIEELDRVIGIARVKAFHLNDSQKELGSRVDRHTHIGEGCIGLEGFRALVNDERFAGLPMVLETPKGDD 268
>gi|90580592|ref|ZP_01236397.1| endonuclease IV [Vibrio angustum S14] >gi|90438250|gb|EAS63436.1| endonuclease IV [Vibrio angustum S14] (282 aa)
Score = 374, Expect = 4.8e-34, Identities = 93/276 (33%), Positives = 151/276 (54%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           L+G+HV   A   +  + +   +   N F +FT   + ++ K L+ ++I  A K    +       I+ H  YLINLG+P+           I E++R  Q+   L+  HPGS L        +  IA+++N A E   +DV+  +E  AG+GS +G  FE +++I+  VK+K R+GVC+DTCH   +G D+   +  D+T  EF   + + Y++ +HLNDSK ++GS  DRH ++G G +G+D       +++  ++P ILET   D   I+ QEI  L
  S:     3 LIGAHV--SAAGGVFNAPVNAEKIGANAFALFTKNQRQWVAKPLEADVI-AAFKARCSQLEFNANAILPHDSYLINLGAPEAEKLEKSRAAFIDEMSRCKQLGLHLLNFHPGSHLKKISEKECLKLIAESINLAHEQV-SDVVAVIENTAGQGSNLGWQFEHLAEIIDQVKDKTRVGVCIDTCHTFAAGYDLRTETATDRTFAEFDDVVGMQYLRGMHLNDSKGDLGSHLDRHHSLGEGAIGWDCFRYIMQDDRFNHMPLILETINPD---IWHQEIATL 275
>gi|19074955|ref|NP_586461.1| DNA LYASE/ENDONUCLEASE 4 [Encephalitozoon cuniculi GB-M1] >gi|19069680|emb|CAD26065.1| DNA LYASE/ENDONUCLEASE 4 [Encephalitozoon cuniculi GB-M1] (275 aa)
Score = 373, Expect = 6.3e-34, Identities = 91/272 (33%), Positives = 156/272 (57%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKE--KNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKL-ANVPKILETPYRDDKPIYKQE 300
           L+G+H+      + + + +E L  D  C  +F    + ++   + Q     A ++ +   ++P   E IV H  YLIN G+P    +S+    L+ ++ R   +   +  +HPGS+    R   +  I  ++N A+      V + +E MAG+GS VG +FEE+  I+ G+++++RIGVCLDTCH+  +G DI+  +   + +E F + + L ++K +H+NDSK  +GS+KDRH++IG G +G +   ++  N K+  N+P ILETP   D   YK+E
  S:     4 LIGAHLSISKGIHTIQAQMELLGLD-TC-AIFLKSQRRYLTPPMKQG----AAEMFRAHVRHP---ELIVPHGSYLINFGNPDLVDKSM--ECLVDDLERCKSLGIGMYNMHPGSSKGKGRAECLRSIGHHVNTALSRVQG-VTVLIENMAGQGSVVGSSFEELRDIIGGIEDRERIGVCLDTCHLFGAGFDITTEEKFLEVMERFDRVVGLEFLKAMHINDSKEALGSKKDRHESIGKGMIG-EKAFRFIMNSKVFDNIPLILETP---DPGKYKEE 265
>gi|154311164|ref|XP_001554912.1| hypothetical protein BC1G_06700 [Botryotinia fuckeliana B05.10] >gi|150851104|gb|EDN26297.1| hypothetical protein BC1G_06700 [Botryotinia fuckeliana B05.10] (514 aa)
Score = 373, Expect = 6.7e-34, Identities = 90/265 (33%), Positives = 140/265 (52%)
  Q:    25 KNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           K  + +G+HV       +  SV  +    GN F +F    + ++   L     D+   L +E+     + ++ H  YL+NL  P E       +  + ++ R  ++  KL   HPGS   + R  AI  IA  LNKA +AT   VI  +E MAG G+ +G  +E++  I++ V +K R+GVCLDTCH   +G D+  P+   +T++ F K + L Y+K +HLNDSK+ + S +D H NIG G +G        + E   N+P +LETP
  S:   145 KKAVHIGAHV--SGAGGVQNSVNNSSRIGGNAFALFLKSQRKWVNPPLASEARDQFKSLCEEQKYDASKFVLPHCSYLVNLAQPDEEKAKQAYDCFLDDLKRCEELGIKLYNFHPGSTGGNPRPEAIGRIAAQLNKAHKATKT-VITLLENMAGAGNVIGSTWEDLRDIIALVDDKSRVGVCLDTCHTFAAGYDLRSPEAFKETMDGFDKIVGLPYLKALHLNDSKSPLASNRDLHANIGTGFLGLRAFHNVVNFEPFQNMPMVLETP 409
>gi|154249629|ref|YP_001410454.1| apurinic endonuclease Apn1 [Fervidobacterium nodosum Rt17-B1] >gi|154153565|gb|ABS60797.1| apurinic endonuclease Apn1 [Fervidobacterium nodosum Rt17-B1] (292 aa)
Score = 372, Expect = 6.9e-34, Identities = 91/284 (32%), Positives = 156/284 (54%)
  Q:    21 MCMSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           M     +L++G+H+        V    ET+E  GN F +F   P+ +  K  +++ +   ++ +K+ N L  E  + H+ YL+N+ SP++      +  L +E+    ++  K + +HPGS L     V I  I   LN  +E  +  V I +E +  KG  +G NF ++ +I+   K  +RIG+  DTCH +D+G D++ P+   + LEE  + + +  IK +HLND+KN +GS KDRH+NIG G +G + L  +  N   +++P +LETP   D P + ++I  +
  S:     1 MSKKDKELIIGAHMPIGGGFARVPR--ETIEIGGNAFQIFPHNPRQWNAKLPNEDDVVHFLRDVKKYN-LNPEYFLCHSGYLVNVASPRDDVWEKSVELLAIEMKICAKLGIKYLNIHPGSHLGEGEEVGIERIVKALNLVME-KEKSVHIMLENVVMKGGNIGYNFSQMRRIIEQCKYPERIGLTFDTCHGYDAGYDVTKPEGIKKLLEEIDREVGIGRIKFVHLNDTKNTLGSNKDRHENIGNGNLGVEGLKVFLSNPVFSSLPLLLETP--GDNPEHAEDIAKI 281
>gi|167856515|ref|ZP_02479227.1| putative endonuclease 4 [Haemophilus parasuis 29755] >gi|167852362|gb|EDS23664.1| putative endonuclease 4 [Haemophilus parasuis 29755] (291 aa)
Score = 372, Expect = 7.6e-34, Identities = 97/284 (34%), Positives = 155/284 (54%)
  Q:    25 KNKL-LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDIS---DPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +NK+  +G+HV   A   +  +VL ++E   N F +FT   + +    L  + I E  K   + +      I+ H  YLINLG+P+    +      I E+ R +Q+   L+  HPGS L+       +  IA+++N A+++  N V+  +E  AG+GS +G  FE +++I+  V+NK+R+GVCLDTCH+  +G DIS     +QT  +F K +   +++ +HLN SK  + SR DRH  +  G +G D      +N    N+P ILET    +  I+ +EI  L S E
  S:     8 ENKMKYIGAHV--SASGGVENAVLRSVEIGANAFALFTKNQRQWQAPPLKADTI-EKFKRFCQVHHFSPAQILPHDSYLINLGNPEAENLAKSREAFIDEMRRCDQLGLTLLNFHPGSHLNKISEQDCLARIAESINIAVDSVPN-VVAVIENTAGQGSNLGWRFEHLAEIIEQVENKQRVGVCLDTCHLFSAGYDISSLASCEQTFADFDKVVGFEFLRGMHLNGSKTLLASRVDRHHTLREGTIGTDVFKFIMNNVHFDNIPLILETI---EPEIWAEEINFLRSLE 289
>gi|168225267|ref|ZP_02650498.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Javiana str. GA_MM04042433] (285 aa)
Score = 372, Expect = 7.8e-34, Identities = 92/282 (32%), Positives = 146/282 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +G+HV   A   L  +     E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P         +  + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T   F K +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P ILET   D   I+ +EI  L +++  E
  S:     4 IGAHV--SAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDD-FKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAGFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDARFDGIPLILETINPD---IWAEEIAWLKAQQIAE 282
>gi|71030516|ref|XP_764900.1| apurinic/apyrimidinic endonuclease [Theileria parva strain Muguga] >gi|68351856|gb|EAN32617.1| apurinic/apyrimidinic endonuclease, putative [Theileria parva] (422 aa)
Score = 371, Expect = 9.0e-34, Identities = 94/277 (33%), Positives = 156/277 (56%)
  Q:    25 KNKLLLGSHVGFKA-KNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKN--PLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRD-DKPIYKQEI 301
           K+ + +G+HV      +  VG+    L   G  F +F    + +   +L ++ I++    M   N  P     ++ HA YLIN+ +P    R    +  + +I R   +   L   HPGS     +++  I HI+D +NKA+E T   V I +E  AG+ + +G  FE++ +I+  V++K R+G+CLDTCH+  +G DI      D+ ++EF K + L Y++ +HLNDSK+++GS  DRH+NIG GK+         ++    N+P ILETP  + ++ +YKQE+
  S:   137 KSNVYIGAHVSASGGPDNSVGNAYNIL---GQAFALFLKNQRTWNWTDLSKSAIEKFQINMLNHNYDPKF---VLPHASYLINVANPDPEKRKRAFDNFLDDIQRCEVLGITLYNFHPGSTCGLCEKSEGIQHISDCINKALEMTKG-VTIVLENAAGQKNVIGSKFEDLRQIIDKVEDKSRVGICLDTCHLFAAGYDIRTTEQFDEVMKEFDKVVGLKYLRAVHLNDSKSDLGSGLDRHENIGKGKLSEQTFRFIVNSPYFKNMPIILETPVPEGNEEVYKQEV 414
>gi|50305755|ref|XP_452838.1| unnamed protein product [Kluyveromyces lactis] >gi|49641971|emb|CAH01689.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140] (368 aa)
Score = 371, Expect = 9.3e-34, Identities = 96/288 (33%), Positives = 150/288 (52%)
  Q:    24 SKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLI----DEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           + +K   G+HV       +  SV    E   N F +F   P+ +  K   ++ I    +   KL  +       +I+ H  Y INLG+P         +  + ++ R  Q+       HPGS+LD D +  +  +A  +NKAI  T   V I +E MAG G+ +G N E++  ++  +++K R+GVC+DTCH + +G DIS     DQ  ++F   +   Y+K IHLNDSK  + +  DRH+ +G G +G +     AH+E L  +P +LETP ++D   Y +EI  L   EW E
  S:    20 TTSKFKFGAHV--SGAGGISNSVTNAHEIGCNSFAMFLKSPRQWNSKPYPESEITKFNENCAKLSYDPK----TDILPHGSYFINLGNPDHEKAEKAYDAFLDDLVRCEQLGIGHYNFHPGSSLDGDHDTQLKQLAGYINKAINDT-KFVNIVLENMAGHGNLIGSNLEDLKTVIDMIEDKNRVGVCVDTCHTYAAGYDISTKNAFDQFWKKFDAIIGFKYLKAIHLNDSKAPLAANADRHEILGQGFLGLEVFKIIAHSEFLQGIPIVLETPQKEDAG-YGEEIKLL---EWLE 303
>gi|190345048|gb|EDK36860.2| hypothetical protein PGUG_00958 [Pichia guilliermondii ATCC 6260] (360 aa)
Score = 371, Expect = 1.0e-33, Identities = 83/280 (29%), Positives = 145/280 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEW 309
            G+HVG  +   +  SVL  ++   N F +F   P+ +    L     ++   L  +       +++ H  Y+IN+ +P +          + ++ R  ++   L   HPGS +D +++  +  +A  +N+AI+ T   V I +E MAG G+ +G + +++  ++  V +K R+GVC+DTCH   +G DIS      +  ++F   +   Y+  IHLNDSK  + + +D H  +G G +G D     A++ KL  +P +LETP +DD  +Y +EI  L   EW
  S:     3 FGAHVG--SSGGVSKSVLNAMDIGANSFALFLRSPRQWAAPPLSSEEAEKFKALCSQHGYDPARDVLPHGSYMINMANPDDEKAEKSFGLFLDDLQRCEKLGIGLYNFHPGSVIDGEKSDGLEKLASYINRAIKETST-VKIVIENMAGHGNLIGSDLQDIKTVIDFVTDKSRVGVCVDTCHSFAAGYDISTESGYKEFWDKFDSIIGRQYLSAIHLNDSKAPLAANRDLHQKLGLGYLGLDVFRFIANDPKLEGLPIVLETPVKDDDTVYGEEIKLL---EW 279
>gi|171687543|ref|XP_001908712.1| unnamed protein product [Podospora anserina] >gi|170943733|emb|CAP69385.1| unnamed protein product [Podospora anserina] (485 aa)
Score = 371, Expect = 1.1e-33, Identities = 96/282 (34%), Positives = 151/282 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR---------DDKPIYKQEI--------INLNSKEWKE 311
           +G+HV   A   +  S+        N F +F  P + +               L+K  N    + I+ HA YLINL  P +   +   +  + ++ R + +   L   HPGS      + A   IA +LN A +AT + VI  +E M G G+ +G +F +++ I+S V++K R+GVC+DTCH   +G DI  P+   +T+ EF + + L Y+K  HLNDSK    S +D H+NIG G +G        ++E+L N+P +LETP           +DK I+  EI        ++  SKE+K+
  S:   126 IGAHV--SAAGGVQNSITNASSIGANAFAIFLKPHRTWKYPPFSPETPSLFSSLLK-TNTYTPDIILPHASYLINLAQPDKEKSTQAYSSFLDDLKRCDALGITLYNFHPGSTGGLPMSEACARIASHLNTAHKATKS-VITVLENMCGSGNIIGSSFSDLATIISLVEDKSRVGVCVDTCHAFAAGYDIRSPEAYAKTMREFDEVVGLKYLKAFHLNDSKAPFSSHRDLHENIGQGFLGLRAFHNVVNDERLQNIPMVLETPIEVKGPDGKKTEDKKIWADEIKLLESLIGMDAESKEFKD 423
>gi|168818077|ref|ZP_02830077.1| hypothetical protein Salentericaenterica_01725 [Salmonella enterica subsp. enterica serovar Weltevreden str. HI_N05-537] (285 aa)
Score = 371, Expect = 1.1e-33, Identities = 92/282 (32%), Positives = 146/282 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +G+HV   A   L  +     E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P         +  + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T   F K +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P ILET   D   I+ +EI  L +++  E
  S:     4 IGAHV--SAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDD-FKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAGFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDGRFDGIPLILETINPD---IWAEEIAWLKAQQIAE 282
>gi|168220720|ref|ZP_02645952.1| hypothetical protein Senterenterica_10022 [Salmonella enterica subsp. enterica serovar Agona str. SL483] (285 aa)
Score = 371, Expect = 1.1e-33, Identities = 92/282 (32%), Positives = 146/282 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +G+HV   A   L  +     E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P         +  + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T   F K +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P ILET   D   I+ +EI  L +++  E
  S:     4 IGAHV--SAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDD-FKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAGFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDGRFDGIPLILETINPD---IWAEEIAWLKAQQIAE 282
>gi|161502639|ref|YP_001569750.1| endonuclease IV [Salmonella enterica subsp. arizonae serovar 62:z4,z23:--] >gi|189037127|sp|A9MK49|END4_SALAR Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|160863986|gb|ABX20609.1| hypothetical protein SARI_00686 [Salmonella enterica subsp. arizonae serovar 62:z4,z23:--] (285 aa)
Score = 371, Expect = 1.2e-33, Identities = 90/279 (32%), Positives = 146/279 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   L  +     E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P         +  + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  EF + +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P +LET   D   I+ +EI  L +++
  S:     4 IGAHV--SAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLIPQVIDD-FKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGQIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDARFDGIPLVLETINPD---IWAEEIAWLKAQQ 279
>gi|146423302|ref|XP_001487581.1| hypothetical protein PGUG_00958 [Pichia guilliermondii ATCC 6260] (360 aa)
Score = 371, Expect = 1.2e-33, Identities = 83/280 (29%), Positives = 145/280 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEW 309
            G+HVG  +   +  SVL  ++   N F +F   P+ +    L     ++   L  +       +++ H  Y+IN+ +P +          + ++ R  ++   L   HPGS +D +++  +  +A  +N+AI+ T   V I +E MAG G+ +G + +++  ++  V +K R+GVC+DTCH   +G DIS      +  ++F   +   Y+  IHLNDSK  + + +D H  +G G +G D     A++ KL  +P +LETP +DD  +Y +EI  L   EW
  S:     3 FGAHVG--SSGGVSKSVLNAMDIGANSFALFLRSPRQWAAPPLSSEEAEKFKALCSQHGYDPARDVLPHGSYMINMANPDDEKAEKSFGLFLDDLQRCEKLGIGLYNFHPGSVIDGEKSDGLEKLASYINRAIKETST-VKIVIENMAGHGNLIGSDLQDIKTVIDFVTDKSRVGVCVDTCHSFAAGYDISTELGYKEFWDKFDSIIGRQYLSAIHLNDSKAPLAANRDLHQKLGLGYLGLDVFRFIANDPKLEGLPIVLETPVKDDDTVYGEEIKLL---EW 279
>gi|172048403|sp|A8Z6D9|END4_CAMC1 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|158604895|gb|ABW74720.1| endonuclease 4 (Endonuclease IV) (EndodeoxyribonucleaseIV) [Campylobacter concisus 13826] (283 aa)
Score = 371, Expect = 1.2e-33, Identities = 89/279 (31%), Positives = 161/279 (57%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   +  + +   +   N F +FT   + +  KEL +  I E  K   + + +  ++++ HA YLINLG P++  R+  L   I EI R +++  KL+  HPGS L    +N  +++IA  +N+A++ T   V + +E  A +GS +G +F +++ ++  V ++ R+GVC+DTCH   +G D+   +   +T+ EF   +   ++  +HLND+K  +GS+KDRH+++G G++G        +++K+  +P ILET    D+ I++ EI  L + E
  S:     4 IGAHV--SAAGGVSNAPINAAKIGANAFALFTKNQRQWSAKELSEGEI-EQFKANLKASGISADHVLPHASYLINLGHPEKEARAKSLEAFIDEIERASKLGLKLLNFHPGSHLKQISQNECLDNIARCINEALKRTSG-VKLVIENTAAQGSNLGFDFAQLAYLIERVDDESRVGVCIDTCHAFAAGYDLRSKEAYAKTMGEFDAVIGYKFLSGMHLNDAKFGLGSKKDRHESLGKGELGLGAFENIINDDKIGEIPLILETI---DESIWEDEIKILRNLE 279
>gi|156034695|ref|XP_001585766.1| hypothetical protein SS1G_13282 [Sclerotinia sclerotiorum 1980] >gi|154698686|gb|EDN98424.1| hypothetical protein SS1G_13282 [Sclerotinia sclerotiorum 1980] (574 aa)
Score = 370, Expect = 1.3e-33, Identities = 88/265 (33%), Positives = 140/265 (52%)
  Q:    25 KNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           K  + +G+HV       +  S+  +L   GN F +F    + ++   L     D+     KE+     + ++ H  YL+NL  P E       +  + ++ R  ++  KL   HPGS     R  AI  IA  LNKA +AT   V+  +E MAG G+ +G  +E++  I++ + +K R+GVCLDTCH   +G D+  P+   +T++ FSK + L Y+K +HLNDSK+ + S +D H NIG G +G        + +   N+P +LETP
  S:   206 KQAIHIGAHV--SGAGGVHNSINNSLRIGGNAFALFLKSQKKWVNPPLAPEARDQFKAFCKEEKYDASKYVLPHCSYLVNLAQPDEQKAKQAYDCFLDDLKRCEELGIKLYNFHPGSTGGHPRPEAIARIAAQLNKAHKATKT-VVTLLENMAGAGNVIGSTWEDLRDIIALIDDKSRVGVCLDTCHTFAAGYDLRSPEAFKKTMDGFSKIVGLPYLKALHLNDSKSPLASNRDLHANIGTGFLGLRAFHNVINFKPFQNMPMVLETP 470
>gi|1335852|gb|AAB39924.1| apurinic/apyrimidinic endonuclease (278 aa)
Score = 370, Expect = 1.3e-33, Identities = 79/233 (33%), Positives = 136/233 (58%)
  Q:    57 FMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           F +F    + +  K + + +++   K ++E N   L+ IV H  YL+N GSP+          ++ E  R  ++   +   HPGS +   ++   +  IA+ ++  +E T+N +I+ +ETMAG+G+ +G  FEE+  I+  VK K R+GVC+DTCH+   G DI      ++ ++ F + +  +Y+K IH+NDSK ++GS+ DRH++IG GK+G        ++ +L  +P ILETP
  S:    27 FAMFVRNQRTWNHKPMSEEVVENWWKAVRETN-FPLDQIVPHGSYLMNAGSPEAEKLEKSRLAMLDECQRAEKLGITMYNFHPGSTVGKCEKEECMTTIAETIDFVVEKTEN-IILVLETMAGQGNSIGGTFEELKFIIDKVKVKSRVGVCIDTCHIFAGGYDIRTQKAYEEVMKNFGEVVGWNYLKAIHINDSKGDVGSKLDRHEHIGQGKIGKAAFELLMNDNRLDGIPMILETP 261
>gi|123441779|ref|YP_001005763.1| endonuclease IV [Yersinia enterocolitica subsp. enterocolitica 8081] >gi|166224296|sp|A1JLX8|END4_YERE8 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|122088740|emb|CAL11545.1| endonuclease IV [Yersinia enterocolitica subsp. enterocolitica 8081] (281 aa)
Score = 370, Expect = 1.4e-33, Identities = 95/279 (34%), Positives = 149/279 (53%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGS-ALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
            +G+HV   A   +  +V+   E +   F +FT   + +    L +++I E  K   E+       I+ H  YLINLG P            I E+ R  Q+   L+  HPGS  L  D    +  IA+++N A++AT+  V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+   +D   T       +   Y++ +HLND+K+E  SR DRH ++G G +G   F Y++   H+ +  N+P ILET   D   I+ +EI  L S+
  S:     3 FVGAHV--SAAGGVDQAVIRAHELEATAFALFTKNQRQWRAAPLAEDVI-EKFKQACEQYGYTSAQILPHDSYLINLGHPVTEALEKSREAFIDEMLRCQQLGLSLLNFHPGSHLLQIDEGKCLARIAESINIALDATEG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTEADCQHTFGALGDIVGFEYLRGMHLNDAKSEFNSRVDRHHSLGEGNIGKTVFSYIM---HDPRFDNIPLILETVNPD---IWAEEIAWLKSQ 278
>gi|116180664|ref|XP_001220181.1| hypothetical protein CHGG_00960 [Chaetomium globosum CBS 148.51] >gi|88185257|gb|EAQ92725.1| hypothetical protein CHGG_00960 [Chaetomium globosum CBS 148.51] (470 aa)
Score = 369, Expect = 1.6e-33, Identities = 98/287 (34%), Positives = 154/287 (53%)
  Q:    25 KNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVK----LMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKP---------IYKQEI--------INLNSKEWKE 311
           K  + +G+HV   A   +  S+        N F +F        RK +   L DEA      L+K+ +    ++IV H  YL+NL    ++  +   +  + ++ R   +   L   HPGS   +  + A   IA  LN+A +AT   V+  +E M G G+ VG  FEE+  I++ V +K R+GVC+DTCH   +G D+  P   D+T+ EF   + L Y++ +H+NDSK   GS +D H NIG G +G        ++EKL  +P +LETP  +  P         I+  EI        ++++S E+KE
  S:   112 KRAMYIGAHV--SAAGGVQNSIQNATHIGANAFALFLKS----QRKWVSPPLADEAKTQFHDLLKQHSYDAGKHIVPHGSYLVNLAQADKTKATQAYDGFLDDLQRCEALGITLYNFHPGSTGGAAMSEACARIAGQLNRAHKATKT-VVTLLENMCGSGNVVGSRFEELRDIIALVDDKARVGVCIDTCHAFAAGYDLRTPAAFDKTMAEFDAVVGLKYLRALHINDSKAPFGSHRDLHANIGTGCLGLRAFHNVMNHEKLQGLPMVLETPIDEKGPDGKTVENKQIWADEIKLLESLIGMDVDSAEFKE 415
>gi|153217264|ref|ZP_01951027.1| endonuclease IV [Vibrio cholerae 1587] >gi|153825889|ref|ZP_01978556.1| endonuclease IV [Vibrio cholerae MZO-2] >gi|194535193|ref|YP_002070376.1| endonuclease IV [Vibrio cholerae RC385] >gi|124113699|gb|EAY32519.1| endonuclease IV [Vibrio cholerae 1587] >gi|149740387|gb|EDM54518.1| endonuclease IV [Vibrio cholerae MZO-2] >gi|150419987|gb|EDN12294.1| endonuclease IV [Vibrio cholerae RC385] >gi|150423890|gb|EDN15830.1| endonuclease IV [Vibrio cholerae AM-19226] (286 aa)
Score = 369, Expect = 1.6e-33, Identities = 93/276 (33%), Positives = 147/276 (53%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           L+G+HV       L  + +   E   N F +FT   + +  K L+ + I  A K   +K     E I+ H  YLINLG+P+           + E+ R +Q+   L+  HPGS L        +  IA+++N A     N VI  +E  AG+GS +G  FE ++ I+  V++K+R+GVCLDTCH   +G D+      D+T  EF + + + Y++ +H+NDSK ++ SR DRH ++G G++G++     A + +   +P ILET    D  I+  EI  L
  S:     5 LIGAHVSASGGVEL--APVRAHEIGANAFALFTKNQRQWAAKPLEASSI-RAFKANCKKWGFGSEAILPHDSYLINLGAPEPEKLDKSRAAFVDEMLRCDQLGLTLLNFHPGSHLQQVSEEACLATIAESINLAHRQVPN-VIAVIENTAGQGSNLGWRFEHLAAIIDQVEDKERVGVCLDTCHTFAAGYDLRTKAACDETFAEFERVVGMHYLRAMHINDSKGKLASRVDRHHSLGMGEIGWECFEYIAQDTRFNGIPLILETI---DPDIWATEIATL 277
>gi|15642357|ref|NP_231990.1| endonuclease IV [Vibrio cholerae O1 biovar eltor str. N16961] >gi|121727496|ref|ZP_01680614.1| endonuclease IV [Vibrio cholerae V52] >gi|147674847|ref|YP_001217863.1| endonuclease IV [Vibrio cholerae O395] >gi|153223026|ref|ZP_01953601.1| endonuclease IV [Vibrio cholerae MAK 757] >gi|153803100|ref|ZP_01957686.1| endonuclease IV [Vibrio cholerae MZO-3] >gi|153820184|ref|ZP_01972851.1| endonuclease IV [Vibrio cholerae NCTC 8457] >gi|153824031|ref|ZP_01976698.1| endonuclease IV [Vibrio cholerae B33] >gi|194532301|ref|YP_002067730.1| endonuclease IV [Vibrio cholerae MO10] >gi|172047593|sp|A5F5R6|END4_VIBC3 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|24636844|sp|Q9KPK7|END4_VIBCH Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|9656929|gb|AAF95503.1| endonuclease IV [Vibrio cholerae O1 biovar El Tor str. N16961] >gi|121630164|gb|EAX62566.1| endonuclease IV [Vibrio cholerae V52] >gi|124118449|gb|EAY37192.1| endonuclease IV [Vibrio cholerae MAK 757] >gi|124121351|gb|EAY40094.1| endonuclease IV [Vibrio cholerae MZO-3] >gi|125618353|gb|EAZ46893.1| endonuclease IV [Vibrio cholerae MO10] >gi|126509268|gb|EAZ71862.1| endonuclease IV [Vibrio cholerae NCTC 8457] >gi|126518447|gb|EAZ75670.1| endonuclease IV [Vibrio cholerae B33] >gi|146316730|gb|ABQ21269.1| endonuclease IV [Vibrio cholerae O395] (286 aa)
Score = 369, Expect = 1.6e-33, Identities = 93/276 (33%), Positives = 147/276 (53%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           L+G+HV       L  + +   E   N F +FT   + +  K L+ + I  A K   +K     E I+ H  YLINLG+P+           + E+ R +Q+   L+  HPGS L        +  IA+++N A     N VI  +E  AG+GS +G  FE ++ I+  V++K+R+GVCLDTCH   +G D+      D+T  EF + + + Y++ +H+NDSK ++ SR DRH ++G G++G++     A + +   +P ILET    D  I+  EI  L
  S:     5 LIGAHVSASGGVEL--APVRAHEIGANAFALFTKNQRQWAAKPLEASSI-RAFKANCKKWGFGSEAILPHDSYLINLGAPEPEKLDKSRAAFVDEMLRCDQLGLTLLNFHPGSHLQQVSEEACLATIAESINLAHRQVPN-VIAVIENTAGQGSNLGWRFEHLAAIIDQVEDKERVGVCLDTCHTFAAGYDLRTKAACDETFAEFERVVGMHYLRAMHINDSKGKLASRVDRHHSLGMGEIGWECFEYIAQDARFNGIPLILETI---DPDIWATEIATL 277
>gi|27364003|ref|NP_759531.1| endonuclease IV [Vibrio vulnificus CMCP6] >gi|31076698|sp|Q8DEP6|END4_VIBVU Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|27360120|gb|AAO09058.1|AE016798_218 Endonuclease IV [Vibrio vulnificus CMCP6] (293 aa)
Score = 369, Expect = 1.6e-33, Identities = 95/284 (33%), Positives = 156/284 (54%)
  Q:    21 MCMSKNKL---LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLL----ENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           M  SKN+     +G+HV   A   +  + L   E   N F +FT   + ++ K L++  I        + N  LL    + I+ H  YLINLG+P+           I E+ R   +   L+  HPGS L+       ++ IA+++N A +A   DV+  +E  AG+GS +G  FE +++I+  V++K R+GVCLDTCH   +G D+  P   + T  EF + + + Y++ +H+NDSK ++ S+ DRH  +G G++G+D     A + +  ++P ILET    +  ++ QEI  L
  S:     1 MTNSKNRFGNKFIGAHV--SAAGGVDNAPLRAREIGANAFALFTKNQRQWVAKPLEEKTISAF-----KANCALLGFSPQQILPHDSYLINLGAPEAEKLEKSRLAFIDEMERCQLLGLNLLNFHPGSHLEKISEKACLSLIAESINLAHQAVP-DVVAVIENTAGQGSNLGWRFEHLAEIIEQVEDKSRVGVCLDTCHTFAAGYDLRTPEACETTFAEFERVVGMHYLRAMHINDSKVKLASKVDRHHALGKGEIGWDCFEYIAKDSRFDSIPLILETI---EPELWPQEIEQL 284
>gi|154174687|ref|YP_001407428.1| endonuclease 4 (endonuclease IV) (endodeoxyribonucleaseiv) [Campylobacter curvus 525.92] >gi|166224274|sp|A7GW36|END4_CAMC5 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|112803259|gb|EAU00603.1| endonuclease 4 (Endonuclease IV) (EndodeoxyribonucleaseIV) [Campylobacter curvus 525.92] (283 aa)
Score = 369, Expect = 1.8e-33, Identities = 89/272 (32%), Positives = 150/272 (55%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           +G+HV   A   +  + L   +   N F +F    + +  K L+   I E  +  K  N +   +I+ H  YLINLG   ++ R    N  + EI R +++  +L+  HPGS L+   +N  +N IA+ +N+A++ TD  V + +E  AG+GS +G  FE+++ ++    +K R+GVC+DTCH   +G D+  P+   +T++EF   +   ++  +HLND K  + SRKDRH+++G G +G        ++E +  +P ILET    D  I+  EI
  S:     4 IGAHV--SASGGVQNAPLNAAKIGANAFALFVKNQRQWSAKPLESAAISEFEQNCKAAN-ISPRHILPHDSYLINLGHYDDAKREQSFNAFVDEIERVSELGLELLNFHPGSHLNEISQNECLNLIAECMNEALKRTDG-VKLVIENTAGQGSNLGFRFEQLAYLIERTDDKSRVGVCIDTCHAFAAGYDLRTPEAYKKTMDEFDAVIGYEFLSAMHLNDCKFGLNSRKDRHESLGKGFLGLKAFECIMNDEHIGEIPMILETI---DDSIWADEI 272
>gi|195999302|ref|XP_002109519.1| hypothetical protein TRIADDRAFT_21078 [Trichoplax adhaerens] >gi|190587643|gb|EDV27685.1| hypothetical protein TRIADDRAFT_21078 [Trichoplax adhaerens] (382 aa)
Score = 368, Expect = 2.0e-33, Identities = 80/197 (40%), Positives = 120/197 (60%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR 291
           I+ H  YL+N GSP   T     N LI E+ R  ++   L   HPGS+  +  R   I  IA+++N A  AT N VI  +E M+ + + +G +FEE+++I++ V +K R+GVCLDTCH   +G DI+      +T++EF   +   Y++ +H+NDSK E+G   DRH+NIG GK+G        ++ +L N+P ILETP R
  S:   166 ILPHGSYLMNCGSPNPDTLQKSRNALIDELKRCEKLGLMLYNFHPGSSRGEISRTECIQLIAESINIAHRAT-NKVITVIENMSNQKNVIGGSFEELAEIINRVDDKSRVGVCLDTCHTFAAGYDIASKKGYKKTMDEFDSVVGFQYLRAMHINDSKGELGCHLDRHENIGKGKIGLKAFKLIMNDSRLNNIPMILETPSR 365
>gi|188533419|ref|YP_001907216.1| Endodeoxyribonuclease IV [Erwinia tasmaniensis] >gi|188028461|emb|CAO96323.1| Endodeoxyribonuclease IV [Erwinia tasmaniensis] (280 aa)
Score = 368, Expect = 2.5e-33, Identities = 94/279 (33%), Positives = 148/279 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   +  +V    E +   F +FT   + +    L   +I  A +L  EK+      I+ H  YLINLG P         +  + E+NR  Q+   L+  HPGS L     +  +  IA+++N  +  T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH    G D+   +    T  EF + +   Y++ +HLND+K+E  SR DRH ++G G +G   F +L+K   +++   +P ILET    D  I+K EI  L S++
  S:     4 IGAHV--SAAGGVDRAVERASELEATAFALFTKNQRQWHAAPLTDEVI-SAFRLACEKHRYTPAQILPHDSYLINLGHPVAEALEKSRDAFLDEMNRCQQLGLTLLNFHPGSHLQQITEDECLKRIAESINIVLNNTAG-VTAVIENTAGQGSNLGFRFEHLAAIIDGVEDKSRVGVCIDTCHAFAGGYDLRSEEACVNTFAEFERIVGFQYLRGMHLNDAKSEFNSRVDRHHSLGEGNIGKAAFSWLMK---DKRFDGIPMILETI---DPEIWKDEIAWLKSEQ 279
>gi|168236382|ref|ZP_02661440.1| endonuclease IV [Salmonella enterica subsp. enterica serovar Schwarzengrund str. SL480] >gi|194736559|ref|YP_002115292.1| endonuclease 4 [Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633] >gi|194712061|gb|ACF91282.1| endonuclease 4 [Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633] (285 aa)
Score = 367, Expect = 2.6e-33, Identities = 92/282 (32%), Positives = 145/282 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           +G+HV   A   L  +     E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P            + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T   F K +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P ILET   D   I+ +EI  L +++  E
  S:     4 IGAHV--SAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDD-FKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRVAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAGFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDARFDGIPLILETINPD---IWAEEIAWLKAQQIAE 282
>gi|152993825|ref|YP_001359546.1| endonuclease IV [Sulfurovum sp. NBC37-1] >gi|166224292|sp|A6QCI0|END4_SULNB Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|151425686|dbj|BAF73189.1| endonuclease IV [Sulfurovum sp. NBC37-1] (296 aa)
Score = 367, Expect = 2.7e-33, Identities = 93/273 (34%), Positives = 159/273 (58%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL------DSDRNV--------AINHIADNLNKAIEATD-NDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
            +G+HV   A   +  + L  +      F VF    + ++ K L++  I EA K   E   +L ++++ H  YLINLG P+E          I E+ R NQ+    +  HPGS L      D + +          ++ IA+++N AIEAT  +DV + +E  AG+G+ +G  FE ++ ++  V++K R+GVCLDTCH   +G D+      D+T++ F + +   Y+  +H+NDSK ++GSR DRH ++G G++G+D      ++ ++ ++P ILET    D+ ++ +EI
  S:     3 FVGAHV--SASGGVDNAPLNAMAIGAKAFAVFAKNQRQWVAKPLEEKTI-EAFKKNLETAGILPKHVLPHDSYLINLGHPEEEKLEKSRAAFIDELERCNQLGLDKLNFHPGSHLVKIPKKDPEYHEKLMEAELHCLDVIAESMNLAIEATKGSDVKLVIENTAGQGTNLGYKFEHLAHLIEKVEDKSRVGVCLDTCHTFTAGYDLRTREAYDETMDAFERIVGFEYLMGMHINDSKPKLGSRVDRHASLGQGEIGWDAFCFIMNDPRMDDIPLILETI---DESLWPEEI 287
>gi|150007842|ref|YP_001302585.1| endonuclease IV [Parabacteroides distasonis ATCC 8503] >gi|166224290|sp|A6LB99|END4_PARD8 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|149936266|gb|ABR42963.1| endonuclease IV [Parabacteroides distasonis ATCC 8503] (281 aa)
Score = 367, Expect = 3.0e-33, Identities = 88/251 (35%), Positives = 141/251 (56%)
  Q:    51 EYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLEN---IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           E     F +FT       R+   Q L  +++ L KE+      +   I+ H  YLINLG+P         +  + E+ R  Q+  K++  HPGS L   + +  ++ IA+++N  +  T   V   +E  AG+GS +G  FE+++ I++ V++K R+GVCLDT H   +G DI  P+   +T   F + +  SY++ +HLNDSK E+GSR DRH++IG G +G D       + +  N+P ILETP   D+ ++ +EI
  S:    23 EIGAKAFALFT----RNQRQWKSQPLKADSIHLFKERCEAYGYDPGCILPHDSYLINLGNPDAEGLQKSRDAFLDEMTRCEQLGLKMLNFHPGSHLGKMEVDTCLSRIAESINITLAQTSG-VCAVIENTAGQGSNLGYTFEQIAYIINEVEDKSRVGVCLDTAHTLAAGYDIKTPEGFAETFRHFDEVVGFSYLRGMHLNDSKKELGSRVDRHESIGKGLMGLDTFRMIMVDPRFDNMPLILETP---DEALWPEEI 272
>gi|189192012|ref|XP_001932345.1| DNA-(apurinic or apyrimidinic site) lyase [Pyrenophora tritici-repentis Pt-1C-BFP] >gi|187973951|gb|EDU41450.1| DNA-(apurinic or apyrimidinic site) lyase [Pyrenophora tritici-repentis Pt-1C-BFP] (471 aa)
Score = 367, Expect = 3.0e-33, Identities = 80/260 (30%), Positives = 141/260 (54%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKA-IEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           +G+HV        +  V +T     N F +F    + +  K++DQ  +D  VK  ++      E  + H  YL+NL  P  + +    +  + +++R +++  +L   HPG++  + R   I  I++N+N+A  +     V+  +ETMA  G+ +G NF +++ I+  V +K R+GVCLDTCH+  +G D+  P+   +T+++F K + L Y+K  H+NDSK    S +D H  IG G +G        ++E+   +P +LETP
  S:   125 IGAHVS-------IAGVAKTDLTSANAFAMFMKNQRKWESKDIDQEHVDFFVKWCEDHKINAAECCLPHGSYLVNLAHPDPAHKKQSYDSFLNDLSRCHRLGIRLYNFHPGNSNATTREEGIITISENINQAHADPASGKVVTVLETMASLGNTIGGNFTDIAAIIRLVNDKSRVGVCLDTCHVFAAGYDLRTPEAYAKTIDKFDKEIGLEYLKAFHVNDSKAPFSSHRDVHARIGTGYLGLQAFHNLMNDERFHGLPMVLETP 381
>gi|118474719|ref|YP_892797.1| endonuclease 4 [Campylobacter fetus subsp. fetus 82-40] >gi|166224275|sp|A0RRG4|END4_CAMFF Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|118413945|gb|ABK82365.1| endonuclease 4 [Campylobacter fetus subsp. fetus 82-40] (282 aa)
Score = 367, Expect = 3.2e-33, Identities = 92/277 (33%), Positives = 155/277 (55%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           +G+HV   A   +  + L       + F +F    + +  K L ++ I      +K  N + LE+I+ H  YLINLG P    R   ++  + EI R + +  K+I  HPGS L   D N+ +++I+ ++N  +E +   + + +E  AG+GS +G  FE +  +V    +K RIGVC+DTCH+  SG DI   S  ++T+++F K +   ++  +HLNDSK ++ SRKDRH+++G G +G+       +++++  +P ILET    D  I+  EII L +
  S:     4 IGAHV--SASGGVSNAPLNAKSIGADAFALFVKNQRQWSAKPLTKSEISSFKTNLKNAN-ISLEHILPHNSYLINLGHPDPQQRKKSIDAFLDEIYRCDLLDLKMINFHPGSHLKEIDENICLSNISSSINYILENSSG-IKLVIENTAGQGSNMGFKFEHLGYLVKNSCDKNRIGVCIDTCHLFCSGYDIRSKSAYEKTMDDFGKIVGFEFLSGMHLNDSKCDLASRKDRHESLGKGCIGWSGFENIMNDKRIDEIPLILETI---DNSIWADEIIALRN 277
>gi|37678838|ref|NP_933447.1| endonuclease IV [Vibrio vulnificus YJ016] >gi|39930934|sp|Q7MNR1|END4_VIBVY Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|37197579|dbj|BAC93418.1| endonuclease IV [Vibrio vulnificus YJ016] (293 aa)
Score = 367, Expect = 3.2e-33, Identities = 95/284 (33%), Positives = 155/284 (54%)
  Q:    21 MCMSKNKL---LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLL----ENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           M  SKN+     +G+HV   A   +  + L   E   N F +FT   + ++ K L++  I        + N  LL    + I+ H  YLINLG+P+           I E+ R   +   L+  HPGS L+       +  IA+++N A +A   DV+  +E  AG+GS +G  FE +++I+  V++K R+GVCLDTCH   +G D+  P   + T  EF + + + Y++ +H+NDSK ++ S+ DRH  +G G++G+D     A + +  ++P ILET    +  ++ QEI  L
  S:     1 MTNSKNRFGNKFIGAHV--SAAGGVDNAPLRAREIGANAFALFTKNQRQWVAKPLEEKTISAF-----KANCALLGFSPQQILPHDSYLINLGAPEAEKLEKSRLAFIDEMERCQLLGLNLLNFHPGSHLEKISEKACLYLIAESINLAHQAVP-DVVAVIENTAGQGSNLGWRFEHLAEIIEQVEDKSRVGVCLDTCHTFAAGYDLRTPEACEATFAEFERVVGMHYLRAMHINDSKVKLASKVDRHHALGKGEIGWDCFEYIAKDSRFDSIPLILETI---EPELWPQEIEQL 284
>gi|153093549|gb|EDN74529.1| endodeoxyribonuclease IV [Mannheimia haemolytica PHL213] (281 aa)
Score = 367, Expect = 3.2e-33, Identities = 93/281 (33%), Positives = 151/281 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQT---LEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWK 310
           +G+HV   A   +  +VL ++E   N F +FT   + +    L    I++  +  K  +    E I+ H  YLINLG+P+           I E++R NQ+  KL+  HPG+ L        +  IA+++N A+E   N VI  +E  AG+GS +G +F+ ++ I+  V++K R+GVCLDTCH+  +G DIS  +++     +F++ +   Y++ +HLN SK  +GSR DRH  +  G +G +       N    ++P ILET   +   I+  EI  L + E K
  S:     4 IGAHV--SASGGVENAVLRSVEIGANAFALFTKNQRQWQAPALKAETIEKFKRFCKVHH-FSAEQILPHDSYLINLGNPEAEALEKSRVAFIDEMSRANQLGLKLLNFHPGAHLKQISEQDCLARIAESINIAVEKVPN-VIAVIENTAGQGSNLGWHFDHLATIIEQVEDKSRVGVCLDTCHLFSAGYDISSYEKSEAVFNDFNQTVGFHYLRGMHLNGSKTPLGSRVDRHHTLREGTIGTEVFAFIMQNMHFNHIPMILETISPE---IWADEIKFLRTLELK 281
>gi|46108932|ref|XP_381524.1| hypothetical protein FG01348.1 [Gibberella zeae PH-1] (456 aa)
Score = 367, Expect = 3.3e-33, Identities = 92/287 (32%), Positives = 151/287 (52%)
  Q:    25 KNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR---------DDKPIYKQEI--------INLNSKEWKE 311
           K  + +G+HV   A   +  SV   +    N F +F    + +    LD    ++ + L K+ +    E+ + H  YL+NL    E   +      + ++ R  Q+  +L   HPGS     R  AI  IA  LNK+ +AT   V+  +E MAG G+ +G  +E++  I+  V++K R+GVC+DTCH   +G+D+  P+   +T + F++ +   Y+K  HLNDSK    S++D H NIG G +G        ++   A +P +LETP           +DK ++  EI        ++  S E+KE
  S:   104 KPAMHIGAHV--SAAGGVQNSVTNAIHIGANAFALFLKSQRKWANPPLDSEAKNQFISLCKDHSYSANEHALPHGSYLVNLAQADEDKANQAYTSFVDDLQRCEQLGIRLYNFHPGSTGGDARPAAIGRIAAQLNKSHKATKT-VVTVLENMAGSGNVIGSTWEDLRDIIELVEDKSRVGVCIDTCHAFAAGLDLRTPEAFKKTFDSFNEIVGHEYLKAFHLNDSKAPFNSKRDLHANIGTGFLGLRAFHSIMNHAPFAGMPMVLETPIDRPGADGKSVEDKKVWADEIKLLERLVGMDAESDEFKE 407
>gi|194682209|emb|CAR41906.1| endonuclease IV [Proteus mirabilis HI4320] (281 aa)
Score = 366, Expect = 3.5e-33, Identities = 95/280 (33%), Positives = 151/280 (53%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID---ISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
            +G+HV   A   +  +VL   E     F +FT   + +    L    ID+  K   E        I+ H  YLINLG P+E          + E+ R  Q+  +L+  HPGS L   D +  +  IA+++N  ++ T N V   +E  AG+G+ +G  FE ++ I+ GV++K R+GVC+DTCH   +G D   + D ++T  EF   +   Y+K +HLND+K+E+ SR DRH ++G G +G   F Y+++   + +   +P ILET   D   I+ +EI  L S++
  S:     3 FVGAHV--SAAGGVDQAVLRAHEIKATAFALFTKNQRQWKAAPLSTESIDK-FKKNCEIYGYGPAQILPHDSYLINLGHPEEEALEKSRAAFLDEMQRCEQLGIELLNFHPGSHLKKIDVDKCLQRIAESINITLDKTQN-VTAVIENTAGQGTNLGYRFEHLAAIIDGVEDKSRVGVCIDTCHTFAAGYDLRTVEDCEKTFAEFDNIVGFQYLKAMHLNDAKSELASRVDRHHSLGQGNIGKVPFTYIMQ---DIRFDGIPLILETINPD---IWPEEIAWLKSQQ 279
>gi|153828825|ref|ZP_01981492.1| endonuclease IV [Vibrio cholerae 623-39] >gi|148875701|gb|EDL73836.1| endonuclease IV [Vibrio cholerae 623-39] (286 aa)
Score = 366, Expect = 3.5e-33, Identities = 92/276 (33%), Positives = 147/276 (53%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           L+G+HV       L  + +   E   N F +FT   + +  K L+ + I  A K   +K     E I+ H  YLINLG+P+           + E+ R +Q+   L+  HPGS L        +  I++++N A     N VI  +E  AG+GS +G  FE ++ I+  V++K+R+GVCLDTCH   +G D+      D+T  EF + + + Y++ +H+NDSK ++ SR DRH ++G G++G++     A + +   +P ILET    D  I+  EI  L
  S:     5 LIGAHVSASGGVEL--APVRAHEIGANAFALFTKNQRQWAAKPLEASSI-RAFKANCKKWGFGSEAILPHDSYLINLGAPEPEKLDKSRAAFVDEMLRCDQLGLTLLNFHPGSHLQQVSEEACLATISESINLAHRQVPN-VIAVIENTAGQGSNLGWRFEHLAAIIDQVEDKERVGVCLDTCHTFAAGYDLRTKAACDETFAEFERVVGMHYLRAMHINDSKGKLASRVDRHHSLGMGEIGWECFEYIAQDARFNGIPLILETI---DPDIWATEIATL 277
>gi|77974770|ref|ZP_00830308.1| COG0648: Endonuclease IV [Yersinia frederiksenii ATCC 33641] (281 aa)
Score = 366, Expect = 3.6e-33, Identities = 96/279 (34%), Positives = 151/279 (54%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL---DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
            +G+HV   A   +  +V+   + +   F +FT   + +    L + +I E  K   E+       I+ H  YLINLG P            I E+ R  Q+   L+  HPGS L   D D+ +A   IA+++N A+ AT+  VI  +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+    D  +T       +   Y++ +HLND+K+E  SR DRH ++G G +G   F Y+++   + +  N+P ILET   D   I+ +EI  L S+
  S:     3 FVGAHV--SAAGGVDQAVIRAHQLEATAFALFTKNQRQWRAAPLAEEVI-EKFKQACEQYGYTSAQILPHDSYLINLGHPVTEALEKSREAFIDEMVRCQQLGLSLLNFHPGSHLLQIDEDKCLA--RIAESINIALNATEG-VIAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTEEDCQRTFAALGDIVGFQYLRGMHLNDAKSEFNSRVDRHHSLGEGNIGKTVFSYIMR---DSRFDNIPLILETVNPD---IWAEEIAWLKSQ 278
>gi|77976349|ref|ZP_00831845.1| COG0648: Endonuclease IV [Yersinia intermedia ATCC 29909] (283 aa)
Score = 366, Expect = 3.8e-33, Identities = 95/279 (34%), Positives = 153/279 (54%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL---DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
            +G+HV   A   +  +V+   E +   F +FT   + +    L +++I E  K   E        I+ H  YLINLG P            I E+ R  Q+   L+  HPGS L   D D+ +A   IA+++N A++ ++  V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+    D + T ++ S  +   Y++ +HLND+K+E  SR DRH ++G G +G   F Y+++   + +  N+P ILET   D   I+ +EI  L S+
  S:     3 FVGAHV--SAAGGVDQAVIRAHELEATAFALFTKNQRQWRAAPLAEDVI-EKFKQACELYGYTSAQILPHDSYLINLGHPVTDALDKSREAFIDEMARCQQLGLSLLNFHPGSHLLQIDEDKCLA--RIAESINMALDVSEG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTEDDCEHTFKQLSNIVGFQYLRGMHLNDAKSEFNSRVDRHHSLGEGNIGKTVFSYIMR---DPRFDNIPLILETVNPD---IWAEEIAWLKSQ 278
>gi|66361854|ref|XP_627891.1| AP endonuclease of the TIM barrel fold, possible bacterial horizontal transfer [Cryptosporidium parvum Iowa II] >gi|46227657|gb|EAK88592.1| AP endonuclease of the TIM barrel fold, possible bacterial horizontal transfer [Cryptosporidium parvum Iowa II] (364 aa)
Score = 366, Expect = 4.1e-33, Identities = 98/277 (35%), Positives = 149/277 (53%)
  Q:    25 KNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP-YRDDKPIYKQEI 301
           K +  +G+HV   A   +  SV  ++   G  F +F  P + +    L Q  ID   K  +       +  + H  YLINLG+P E  RS        E+ R + +  KL   HPGS +    +  +I  I+D +NKA E T + VI  +E  A +   VG  F+E+S+I+  VK+K RIGVCLDTCH+  +G D+   +   + + EF   + L Y+K +HLNDSK +  S  DRH+N+G G +G +      ++ +  ++P ILETP   +D  +YK+EI
  S:    76 KYRKFVGAHV--SASGGVDKSVNNSMNIAGMAFSMFLKPSRGWNAPPLKQQTIDLFKKNCETNKIEYCKFCIPHGSYLINLGNPDEEKRSKMYGAFEDELKRCDALGIKLYNFHPGSTVGQCSKEESIQFISDCINKAHEQTKS-VITVLENCA-ESKCVGYRFKELSEIIERVKDKSRIGVCLDTCHLFAAGYDVRTAESFNKVMVEFEAVIGLKYLKAMHLNDSKGQFNSGLDRHENLGKGNIGMECFKFIMNDSRFNDIPLILETPDPNNDDKVYKKEI 353
>gi|189347257|ref|YP_001943786.1| apurinic endonuclease Apn1 [Chlorobium limicola DSM 245] >gi|189341404|gb|ACD90807.1| apurinic endonuclease Apn1 [Chlorobium limicola DSM 245] (290 aa)
Score = 366, Expect = 4.3e-33, Identities = 76/200 (38%), Positives = 122/200 (61%)
  Q:    93 ENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRD 292
           E+I+ H  YLINLGSP+        N    E+ R  ++  K++  HPGS L+  + +  +  IA+++N A++ +   V   +E  AG+G+ +G +F++++ I+  V++K R+GVCLDTCH+   G DI      D+TL+EF + + + Y+K +HLND+K  +GSR DRH+ IG G +G +       +  L  +P ILETP  D
  S:    64 EHILPHDSYLINLGSPEPDKLDRSRNAFFDEMQRVERLGLKMLNFHPGSHLNQIEPDACLQLIAESVNMALDRSCC-VTAVIENTAGQGTNLGRSFDDLACIIDHVEDKSRVGVCLDTCHLFAGGYDIRTKEALDRTLDEFDRIVGIRYLKAMHLNDAKQPLGSRLDRHECIGKGAIGIEAFTAIMQHPLLDELPLILETPDSD 266
>gi|112434021|gb|ABI18361.1| endonuclease IV [Enterobacter pyrinus] (285 aa)
Score = 365, Expect = 4.8e-33, Identities = 90/279 (32%), Positives = 145/279 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   +  + +   E     F +FT   + +    L   +I E  K    K     E I+ H  YLINLG P E          I E+ R  Q+   L+  HPGS L     +  +  IA+++N A+  T+  V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+      ++T  +F + +  +Y++ +HLND+K+  GSR DRH+++G G +G D       + +   +P ILET   D   I+ +EI  L +++
  S:     4 IGAHV--SASGGVANAAIRASEIGATAFALFTKNQRQWRASPLTDEVISE-FKAACAKYGYGPEQILPHDSYLINLGHPVEEALEKSREAFIDELARCQQLGLTLLNFHPGSHLMQIPVDACLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTEEACEKTFADFERIVGFNYLRGMHLNDAKSAFGSRVDRHNSLGEGNIGHDAFRWIMRDSRFDGIPLILETTNPD---IWAEEIAWLKAQQ 279
>gi|89072523|ref|ZP_01159095.1| endonuclease IV [Photobacterium sp. SKA34] >gi|89051627|gb|EAR57080.1| endonuclease IV [Photobacterium sp. SKA34] (282 aa)
Score = 365, Expect = 5.0e-33, Identities = 93/278 (33%), Positives = 152/278 (54%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           L+G+HV   A   +  + +   +   N F +FT   + ++ K L+ + I  A K    +       I+ H  YLINLG+P+           I E++R  Q+   L+  HPGS L        +  IA+++N A E   +DV+  +E  AG+GS +G  FE +++I+  VK+K R+GVC+DTCH   +G D+   +  D+T  EF+  + + Y++ +HLNDSK ++GS  DRH ++G G +G+D       +++  ++P ILET   D   I+ QEI  L +
  S:     3 LIGAHV--SAAGGVFNAPVNAEKIGANAFALFTKNQRQWVAKPLEGDAI-TAFKARCSQLEFNANAILPHDSYLINLGAPEAEKLEKSRVAFIDEMSRCKQLGLHLLNFHPGSHLKKISEKKCLKLIAESINLAHEQV-SDVVAVIENTAGQGSNLGWRFEHLAEIIDQVKDKTRVGVCIDTCHTFVAGYDLRTEAATDRTFVEFNDVVGMQYLRGMHLNDSKGDLGSHLDRHHSLGEGAIGWDCFRYIMQDDRFNHMPLILETINPD---IWHQEIATLRA 277
>gi|77960397|ref|ZP_00824270.1| COG0648: Endonuclease IV [Yersinia mollaretii ATCC 43969] (283 aa)
Score = 365, Expect = 5.4e-33, Identities = 95/279 (34%), Positives = 153/279 (54%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL---DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
            +G+HV   A   +  +V+   E     F +FT   + +    L +++I E  K   E+       I+ H  YLINLG P            I E+ R  Q+   L+  HPGS L   D D+ +A   IA+++N A++A++  V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+   SD + T ++    +   Y++ +HLND+K+E  SR DRH ++G G +G   F Y+++   + +   +P ILET   D   I+ +EI  L S+
  S:     3 FVGAHV--SAAGGVDQAVIRAHELKATAFALFTKNQRQWRAAPLAEDVI-EKFKQACEQYGYTSAQILPHDSYLINLGHPVIEALEKSREAFIDEMARCQQLGLSLLNFHPGSHLLQIDEDKCLA--RIAESINIALDASEG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTESDCEHTFKQLGDIVGFQYLRGMHLNDAKSEFNSRVDRHHSLGEGNIGKTVFSYIMR---DPRFDGIPLILETVNMD---IWAEEIAWLKSQ 278
>gi|156096158|ref|XP_001614113.1| apurinic/apyrimidinic endonuclease Apn1, putative [Plasmodium vivax SaI-1] >gi|148802987|gb|EDL44386.1| apurinic/apyrimidinic endonuclease Apn1, putative [Plasmodium vivax] (394 aa)
Score = 365, Expect = 5.5e-33, Identities = 98/290 (33%), Positives = 151/290 (52%)
  Q:    12 QWLFLKTKEMCMSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEK---NPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP-YRDDKPIYKQEI 301
           +W   +T E       + LG+H+   A   +  +        G  F +F        RK    +L  E++K  ++      L  + I+ H  YLINL +P    R       + ++ R  Q++  L   HPGS          I ++AD +N+  + T N V+I +E  AG+ + VG  FE++  I+S +++K RIGVCLDTCH   +G DI      D  +++F + +D SY+K +HLNDSK+E+GS  DRH+NIG GK+  +            N+P ILETP   +D+ +YK EI
  S:    87 RWNDFRTIEKYTEITNVYLGAHI--SAGGGVQNAPTNCFNVAGQAFALFL----KNQRKWESPSLSPESIKQFEQNCKAYKLDAKYILPHGSYLINLANPDGEKREKSYLSFLDDVRRCEQLNIPLYNFHPGSTTGMCSLEEGIKNVADCINRVHKETSN-VVIVLENSAGQKNSVGSKFEDLKNIISLIEDKSRIGVCLDTCHTFAAGYDIRSYNGFDLVMKQFDEIIDASYLKAVHLNDSKSELGSGLDRHENIGKGKLSLETFKYVMTARYFKNIPIILETPDVANDESVYKYEI 377
>gi|39970001|ref|XP_366391.1| hypothetical protein MGG_10609 [Magnaporthe grisea 70-15] >gi|145010145|gb|EDJ94801.1| hypothetical protein MGG_10609 [Magnaporthe grisea 70-15] (478 aa)
Score = 364, Expect = 6.1e-33, Identities = 89/282 (31%), Positives = 147/282 (52%)
  Q:    25 KNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR---------DDKPIYKQEIINLNS 306
           K  + +G+HV   A   +  SV    +   N F +F    + +    L  +  D+      + +    ++ + H  YL+NL  P++       +  + ++ R +++  +L   HPGSAL   +  AI  IA  LN++ + T + VI  VE MAG G+ VG  FE++  I+  V++K R+GVC+DTCH   +G D+  P+   +T +EF + +   Y+K  HLNDSK   GS +D H NIG G +G        ++    ++P +LETP           +D+ ++  EI  L S
  S:   123 KRAMYIGAHV--SAAGGVQNSVENAAQIGANAFALFLKSQRKWANPPLAPDARDQFHSSCTKHSYDAAKHCLPHGSYLVNLAQPEKEKADQAYSNFVDDLKRCDELGIRLYNFHPGSALKDTKEAAIGRIAAQLNRSHKETKS-VITVVENMAGSGNVVGSTFEDLRDIIELVEDKSRVGVCIDTCHAFAAGYDLRTPEAFKKTFDEFDRIVGNKYLKAFHLNDSKAPFGSNRDLHANIGTGFLGLRAFHSVVNHAPFQDLPMVLETPIDKKDASGKTVEDRQVWADEIKLLES 413
>gi|154148069|ref|YP_001405851.1| endonuclease 4 (endonuclease IV) (endodeoxyribonucleaseiv) [Campylobacter hominis ATCC BAA-381] >gi|166224276|sp|A7I010|END4_CAMHC Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|153804078|gb|ABS51085.1| endonuclease 4 (Endonuclease IV) (EndodeoxyribonucleaseIV) [Campylobacter hominis ATCC BAA-381] (282 aa)
Score = 364, Expect = 6.2e-33, Identities = 92/272 (33%), Positives = 151/272 (55%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           +G+HV   A   +  + L   +   + F +F    + +  K L+   I+   + +K  + +L E+I+ H  YLINLG P    R   L   I EINR   +  +L+  HPGS L        + +IA+++NKA+ A  N V + +E  AG+GS +G +F++++ I+  V +K RIGVC+DTCH    G D       ++T+ EF   +   ++  +HLND+KNE+G RKDRH+++G G +G +      +++ +  +P ILET    D+ I+  EI
  S:     4 IGAHV--SASGGVSNAPLNAAKIGADAFALFVKNQRQWSAKPLENQEIENFKQNLK-ISKILPEHILAHDSYLINLGHPNLQNRQKSLETFIDEINRCEILGIRLLNFHPGSHLKLISEQECLKNIAESINKAL-ANTNRVKLVIENTAGQGSNLGYHFDQIAFIIKNVSDKSRIGVCIDTCHAFAGGYDFRTKAAYEKTMSEFDAKIGYKFLSGMHLNDTKNELGIRKDRHESLGKGFLGLESFENIMNDKNIDEIPMILETI---DETIWPDEI 272
>gi|183599516|ref|ZP_02961009.1| hypothetical protein PROSTU_02995 [Providencia stuartii ATCC 25827] >gi|188021763|gb|EDU59803.1| hypothetical protein PROSTU_02995 [Providencia stuartii ATCC 25827] (280 aa)
Score = 364, Expect = 6.4e-33, Identities = 97/279 (34%), Positives = 151/279 (54%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           +G+HV   A   +  +V+   E +   F +FT   + +    L + +I E  K    K       I+ H  YLINLG P++          I E+ R  Q+   L+  HPGS L   D +  +  IA+++N A+  T   VI  +E  AG+GS +G  FE ++KI+  V +K R+GVC+DTCH   +G D+      ++T ++FS  +   Y+K +HLND+K+E  SR DRH ++G G +G   F Y++K   + +   +P ILET   D   I+ QEI  L S++
  S:     4 VGAHV--SASGGVDQAVIRAHEINATAFALFTKNQRQWKAPPLSEEVI-EKFKANCAKYGYGKHQILPHDSYLINLGHPEQEALEKSRIAFIDEMQRCEQLGIDLLNFHPGSHLKKIDIDDCLARIAESINIALNETQG-VIAVIENTAGQGSNLGYRFEHLAKIIEDVDDKSRVGVCIDTCHAFAAGYDLRTEEACEETFKQFSDIVGFEYLKGMHLNDAKSEFASRVDRHHSLGEGNIGYTPFSYIMK---DPRFDGIPLILETINPD---IWPQEIAWLKSQQ 279
>gi|17531193|ref|NP_495687.1| APurinic/apyrimidinic endoNuclease family member (apn-1) [Caenorhabditis elegans] >gi|20141264|sp|Q10002|APN1_CAEEL DNA-(apurinic or apyrimidinic site) lyase (Apurinic-apyrimidinic endonuclease) (AP endonuclease) >gi|15718251|emb|CAA87789.2| C. elegans protein T05H10.2, confirmed by transcript evidence [Caenorhabditis elegans] (396 aa)
Score = 363, Expect = 7.7e-33, Identities = 79/233 (33%), Positives = 136/233 (58%)
  Q:    57 FMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           F +F    + +  K + + +++   K ++E N   L+ IV H  YL+N GSP+          ++ E  R  ++   +   HPGS +   ++   +  IA+ ++  +E T+N +I+ +ETMAG+G+ +G  FEE+  I+  VK K R+GVC+DTCH+   G DI      ++ ++ F + +  +Y+K IH+NDSK ++GS+ DRH++IG GK+G        ++ +L  +P ILETP
  S:   145 FAMFVRNQRTWNHKPMSEEVVENWWKAVRETN-FPLDQIVPHGSYLMNAGSPEAEKLEKSRLAMLDECQRAEKLGITMYNFHPGSTVGKCEKEECMTTIAETIDFVVEKTEN-IILVLETMAGQGNSIGGTFEELKFIIDKVKVKSRVGVCIDTCHIFAGGYDIRTQKAYEEVMKNFGEVVGWNYLKAIHINDSKGDVGSKLDRHEHIGQGKIGKAAFELLMNDNRLDGIPMILETP 379
>gi|156362081|ref|XP_001625610.1| predicted protein [Nematostella vectensis] >gi|156212451|gb|EDO33510.1| predicted protein [Nematostella vectensis] (281 aa)
Score = 363, Expect = 8.0e-33, Identities = 93/278 (33%), Positives = 143/278 (51%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
            +G+HV      Y   +V   ++     F +F    + +  K LD    +  ++  K +       I+ H  YL+NLGSP + T +     L+ E+ R  ++   L   HPGS          I  I +++NKA  A    V+  +E M+ +G  +G  FEE+S I+  V++K R+GVC+DTCH   +G DIS     ++ ++ F K + L Y+K IHLNDSK ++G   DRH+NIG G +G     +   + +L  +P ILETP   D   Y +EI  L S
  S:     2 FIGAHVSIAGGLY--KAVHNAVQIGAKAFAMFLRSQRQWNSKPLDDKTAELFIEACKSEG-FAPSTILPHGIYLMNLGSPDDETLTKSRAVLVEELQRCEKLGLTLYNFHPGSTCGKITVQDCIERIGESINKA-HAQTKKVVTVIENMSCQGHTIGGKFEELSDIIDLVRDKSRVGVCIDTCHAFAAGHDISTDKGYEEVMDNFDKIVGLKYLKAIHLNDSKGKLGCHLDRHENIGQGSLGKATFHRIMVDPRLNGIPMILETPCEADN-TYMREIKMLYS 278
>gi|125621333|gb|EAZ49671.1| endonuclease IV [Vibrio cholerae V51] (286 aa)
Score = 363, Expect = 8.4e-33, Identities = 92/276 (33%), Positives = 145/276 (52%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           L+G+HV       L  + +   E   N F +FT   + +  K L+ + I  A K   +K     E I+ H  YLINLG+P+           + E+ R +Q+   L+  HPGS L        +  I +++N A     N VI  +E  AG+GS +G  FE ++ I+  V++K R+GVCLDTCH   +G D+      D+T  EF + + + Y++ +H+NDSK ++ SR DRH ++G G++G++     A + +   +P ILET    D  I+  EI  L
  S:     5 LIGAHVSASGGVEL--APVRAHEIGANAFALFTKNQRQWAAKPLEASSI-RAFKANCKKWGFGSEAILPHDSYLINLGAPEPEKLDKSRAAFVDEMLRCDQLGLTLLNFHPGSHLQQVSEEACLATIXESINLAHRQVPN-VIAVIENTAGQGSNLGWRFEHLAAIIDQVEDKDRVGVCLDTCHTFAAGYDLRTKAACDETFAEFERVVGMHYLRAMHINDSKGKLASRVDRHHSLGMGEIGWECFEYIAQDARFNGIPLILETI---DPDIWATEIATL 277
>gi|194337300|ref|YP_002019094.1| apurinic endonuclease Apn1 [Pelodictyon phaeoclathratiforme BU-1] >gi|194309777|gb|ACF44477.1| apurinic endonuclease Apn1 [Pelodictyon phaeoclathratiforme BU-1] (280 aa)
Score = 363, Expect = 9.6e-33, Identities = 88/255 (34%), Positives = 135/255 (52%)
  Q:    47 LETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           L+        F +FT   + +   +L  + I EA K   E      E+I+ H  YLINLGSP            I E+ R  ++   L+  HPGS L +      +  IA+++N+A++AT   V   +E  AG+G+ +G  FE+++ +V  +++K R+GVCLDTCH+  SG D+      + T  EF + + L Y++ +HLND+   +GSR DRH  IG G +G D      +N     +P ILETP   D   + +EI
  S:    19 LQATSIGAKAFALFTKNQRQWKAPKLTTSSI-EAFKKNCEAGGFRPEHILPHDSYLINLGSPDPEKLQRAREAFIEEMQRAEELGLLLLNFHPGSHLKEIAEERCLELIAESINRALDATKT-VTAVIENTAGQGTNLGNRFEQLAFLVDRIEDKTRVGVCLDTCHLFASGYDLQTTAAIESTFMEFDRIVGLRYLRGMHLNDAMQPLGSRIDRHAGIGKGTIGMDAFRWIMNNPACEEIPLILETP---DSAAWSEEI 272
>gi|90416180|ref|ZP_01224112.1| endonuclease IV [marine gamma proteobacterium HTCC2207] >gi|90331905|gb|EAS47119.1| endonuclease IV [marine gamma proteobacterium HTCC2207] (282 aa)
Score = 363, Expect = 9.7e-33, Identities = 89/277 (32%), Positives = 142/277 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           +G+HV   A   +  + L         F  FT   + +  K L Q  I E  +   E+     E I+ H  YLINLG P+           + E+ R  Q+  K +  HPGS L     N  I  IA+++N A++ T   V   +E  AG+GS +G +FE+++ ++ GV++K R+G+C DTCH   +G D+   D   +  ++F + +   Y+  +HLNDS++E  SR DRH ++G+G +G +       +E+   +P +LET    D  I+  EI  L S
  S:     4 IGAHV--SAAGGIENAPLNAQAIGATAFAFFTKNQRQWQAKPLSQESI-EKFRENCERYDFSPEQILPHDSYLINLGHPETEGLEKSREAFVDELRRCEQLGLKYLNFHPGSHLRKITENQCITKIAESINLALDVTSG-VTAVIENTAGQGSNLGFSFEQLAAMIDGVEDKSRVGICYDTCHAFAAGYDMRSTDGCEKVFDDFQRIVGFDYLCGMHLNDSRSEYASRVDRHHSLGHGNLGLNVFQFIMQDERFDGIPLVLETI---DPSIWADEIELLRS 277
>gi|89092015|ref|ZP_01164970.1| endonuclease IV [Oceanospirillum sp. MED92] >gi|89083750|gb|EAR62967.1| endonuclease IV [Oceanospirillum sp. MED92] (225 aa)
Score = 362, Expect = 1.1e-32, Identities = 78/209 (37%), Positives = 123/209 (58%)
  Q:    93 ENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           E I+ H  YLINLG P+E       +  + E+ R  Q+    +  HPGS L     +  I+ IAD+LN AI  TD+ VI  +E  AG+GS +G +FE+++ I+  V++K R+GVC+DTCHM  +G DI   +   +  + F + +   Y+K +HLNDSK  + S  DRH ++G G++G +       +++   +P +LET    D+ I+ +EI
  S:     6 EQILPHDSYLINLGHPEEEALQKSRDAFLDEMQRCEQLGLVYLNFHPGSHLRKISEDECISRIADSLNWAIAQTDS-VIAVIENTAGQGSNLGFSFEQLAAIIDQVEDKSRVGVCIDTCHMFAAGYDIRTQESCAEVFQSFEEIVGFKYLKGMHLNDSKGGLSSNLDRHHSLGQGEIGLEVFRFIMRDDRFRGIPLVLETI---DETIWAEEI 214
>gi|50121650|ref|YP_050817.1| endonuclease IV [Pectobacterium atrosepticum SCRI1043] >gi|59797732|sp|Q6D3L8|END4_ERWCT Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|49612176|emb|CAG75626.1| endonuclease IV [Erwinia carotovora subsp. atroseptica SCRI1043] (281 aa)
Score = 362, Expect = 1.1e-32, Identities = 94/278 (33%), Positives = 146/278 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
           +G+HV   A   +  +V+   E     F +FT   + +    L   +ID   K   E+   +   I+ H  YLINLG P            I E++R   +   L+  HPGS L   +    +  IA+++N A+  TD  V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH    G D+   +D + T  EF + +   Y++ +HLND+K+  GSR DRH ++G G +G   F Y++K   + +   +P ILET   D   I+  EI  L S+
  S:     4 IGAHV--SAAGGVDQAVIRAHEIKATAFALFTKNQRQWQAAPLSTEVIDR-FKAACEQYAYMSAQILPHDSYLINLGHPDGEALEKSRIAFIDEMSRCQLLGLSLLNFHPGSHLKQIEEADCLARIAESINIALAETDG-VTAVIENTAGQGSNLGFRFEHLAAIIDGVEDKSRVGVCIDTCHAFAGGYDLRTEADCEATFAEFDRIVGFRYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGKTAFSYIMK---DTRFDGIPMILETVNPD---IWADEIAWLKSE 278
>gi|94677036|ref|YP_588835.1| endonuclease IV [Baumannia cicadellinicola str. Hc (Homalodisca coagulata)] >gi|94220186|gb|ABF14345.1| endonuclease IV [Baumannia cicadellinicola str. Hc (Homalodisca coagulata)] (292 aa)
Score = 362, Expect = 1.1e-32, Identities = 94/278 (33%), Positives = 143/278 (51%)
  Q:    27 KLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLD---LSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           K  +G+HV       +  +V+       N F +FT     +    L  NLI +  ++   K       I+ H  YLINL  P +          I E++R  ++   L+  HPGS L   D + +I  IAD++N A+E T   V   VE  AG+GS +G  FE++++I+  V +K RIGVC+DTCH   +G D+      +  F ++ D     Y++ +HLND+K   GSR DRH ++G GK+G+        + +  N+P ILET    +  I+ QEII L
  S:     4 KKWIGAHVSINGG--IDKAVIRAHALHANAFALFTKNQLQWKASTLTINLI-KNFRVACNKYNYTTAQILPHNSYLINLSHPIKDKLKQSRIAFIEELHRCEKLGLSLLNFHPGSHLQQIDEDNSITRIADSINIALEKT-TGVTAVVENTAGQGSNMGFRFEQLAEIIRQVDDKSRIGVCIDTCHAFAAGYDLRTEQSCIATFKQFADTIGFKYLRGLHLNDTKTSCGSRIDRHQSLGQGKIGYTAFNWIMADNRFNNIPIILETI---NPTIWSQEIIWL 278
>gi|21672420|ref|NP_660487.1| endonuclease IV [Buchnera aphidicola str. Sg (Schizaphis graminum)] >gi|24636819|sp|P59058|END4_BUCAP Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|21623030|gb|AAM67698.1| endonuclease IV [Buchnera aphidicola str. Sg (Schizaphis graminum)] (279 aa)
Score = 362, Expect = 1.1e-32, Identities = 90/259 (34%), Positives = 146/259 (56%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVA-INHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDIS---DPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILET 288
           +G+HV   +   L  +V    +     F  FT   + ++   L +  I++  K   + N    E I+ H+ YLINLG P +          I EI R +Q+  + +  HPGS L+    V  ++ I++++N A+E T N V+  +E  AG+G+ +G  FE + +I+  + +K RIGVC+DTCH+  SG D+    D + T  +F   +++ Y+K  HLNDSK +  SR DRH+N+G G++G   F +++K   N+   N+P ILET
  S:     4 IGAHV--SSSGGLEKAVFRAFQIKATTFSFFTKNQRQWISLPLQKKNIEDFKKACIKYN-FSPEKILPHSSYLINLGHPIDFFLEKSRVAFIDEIVRCDQLGLRFLNFHPGSHLNKISEVTCLSRISESINIALEKTKN-VVAVIENTAGQGTNIGYRFEHLYEIIKKIDDKSRIGVCIDTCHLFASGYDLRTKIDYESTFNKFFDLIEMKYLKGFHLNDSKKQFNSRVDRHENLGLGEIGKSVFKWIIK---NKNFHNIPMILET 262
>gi|37526747|ref|NP_930091.1| endonuclease IV [Photorhabdus luminescens subsp. laumondii TTO1] >gi|39930942|sp|Q7N364|END4_PHOLL Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|36786179|emb|CAE15231.1| endonuclease IV (endodeoxyribonuclease IV) [Photorhabdus luminescens subsp. laumondii TTO1] (280 aa)
Score = 362, Expect = 1.1e-32, Identities = 94/273 (34%), Positives = 147/273 (53%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
            +G+HV   A   +  +V+   E     F +FT   + +    L  ++ID+  K   E+       I+ H  YLINLG P+           I E+ R  Q+   L+  HPGS L+  D +  +  IA+++N A+  T   V   +E  AG+G+ +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+   D   QT ++F K +   Y+  +HLND+K+E  SR DRH ++G G +G   F Y++K   + +   +P ILET   D   I+ QEI
  S:     3 FVGAHV--SAAGGVDQAVIRAHELKATAFALFTKNQRQWHAPHLAADVIDK-FKENCERYGYGSRQILPHDSYLINLGHPESEALEKSRLAFIDEMQRCEQLGIDLLNFHPGSHLNKVDVDKCLARIAESINIALNKTQR-VTAVIENTAGQGTNLGFKFEHLAAIIDGVEDKNRVGVCIDTCHAFAAGYDLRTNDVCEQTFQQFEKIVGFQYLCGMHLNDAKSEFASRVDRHHSLGEGNIGKTPFSYIMK---DARFDGIPLILETINPD---IWPQEI 272
>gi|46445979|ref|YP_007344.1| endonuclease IV [Candidatus Protochlamydia amoebophila UWE25] >gi|59797771|sp|Q6MED0|END4_PARUW Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|46399620|emb|CAF23069.1| probable endonuclease IV [Candidatus Protochlamydia amoebophila UWE25] (282 aa)
Score = 362, Expect = 1.3e-32, Identities = 93/282 (32%), Positives = 153/282 (54%)
  Q:    23 MSKNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           MS + LLLG+H       Y   ++LE  +        FT   + +  ++   N I+     +KE N   L +++ H  YLINLG P +            E+ R  Q+    +  HPG++L  D    ++ I ++L         ++ + +E  AG+G+ VG  FE+++ I++GVK++  IGVC+DTCH+  +G DI   S  D TL+ F + + L Y+   H+NDS  ++GSR DRH  +G GK+G   F++L+K   + +  ++PK LETP   D  ++++EI  L
  S:     1 MSHSNLLLGAHTSAAGGVYR--ALLEGKKIGATTIQFFTSNQKQWKGRQFTTNDIELWQSTLKETN---LTHLMSHDSYLINLGCPNQENLLKSRQAFQEEVIRCTQLGINYLNFHPGASLGEDVQKCLDSIVESLLLVRPFIQGNLRLLLEATAGQGTSVGHKFEQLAYIINGVKDELPIGVCIDTCHIFVAGYDIRTSSAWDFTLKGFDRIIGLPYLYAFHINDSSKDLGSRVDRHQPLGEGKIGWESFEFLMK---DSRTRHLPKYLETPGGVD--LWEKEIQKL 278
>gi|76803187|ref|YP_331282.1| endonuclease IV [Natronomonas pharaonis DSM 2160] >gi|121723033|sp|Q3IMK8|END4_NATPD Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|76559052|emb|CAI50650.1| endonuclease IV [Natronomonas pharaonis DSM 2160] (278 aa)
Score = 361, Expect = 1.6e-32, Identities = 83/250 (33%), Positives = 144/250 (57%)
  Q:    45 SVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLL-LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATD--NDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK 294
           +V E LEYDG C  +FT  PQ +     D N+ DE     ++++    +   V+H+ YL+NL +PK+  R   ++ +  E++    +H   + +H G+         +    DN   A+E  D  + V + +E+ AG G+++G  FEE++ ++   +  + + VCLDT HM  +G D+S P+   +T E F + + L +++ IHLNDSK++ G+ KD H +IG GK+G   +  + ++E +A+VP +LETP  + K
  S:    17 AVEEQLEYDGTCGQIFTHSPQVWQ----DPNIGDEEATAFRDRSAEAGVGPWVIHSSYLVNLCTPKDDLREKSIDSMQKEVDAAATLHIPYVNVHLGA----HTGAGVEQGLDNAASALEELDIPDGVTVLIESDAGSGTKLGSTFEELAGVLD--RCDQPLDVCLDTAHMFAAGYDLSTPEGVAETFEAFDETVGLDHLEYIHLNDSKHDCGTNKDEHAHIGEGKIGEAGMRAFINHEAVADVPFVLETPTENGK 262
>gi|149192225|ref|ZP_01870440.1| endonuclease IV [Vibrio shilonii AK1] >gi|148833927|gb|EDL50949.1| endonuclease IV [Vibrio shilonii AK1] (282 aa)
Score = 360, Expect = 2.1e-32, Identities = 83/238 (34%), Positives = 138/238 (57%)
  Q:    51 EYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILET 288
           E   N F +FT   + ++ K L + +I +  KL  +K     E I+ H  YLINLG+P+           I E+ R  Q+   L+  HPGS L     +  ++ IA+++N A +    DVI  +E  AG+G+ +G  FE ++ I+  V++K R+GVCLDTCH   +G D+      + T  EF + + + Y++ +HLNDSK  +G + DRH ++G G++G   F+Y+++   +++  ++P ILET
  S:    23 EIGANAFALFTKNQRQWVAKPLTEEVI-QRFKLECQKYGFRAEQILPHDSYLINLGAPELDKLEKSRAAFIDEMERCQQLGLTLLNFHPGSHLKKLSESDCLDRIAESINLAHQEVP-DVIAVIENTAGQGTNLGWRFEHLAHIIDKVEDKSRVGVCLDTCHTFTAGYDLRTKEACEHTFAEFDRIVGMHYLRAMHLNDSKIPLGGKVDRHHSLGKGEIGWACFEYIMQ---DQRFDSIPLILET 262
>gi|54307762|ref|YP_128782.1| endonuclease IV [Photobacterium profundum SS9] >gi|59797770|sp|Q6LUP5|END4_PHOPR Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|46912185|emb|CAG18980.1| putative endonuclease IV [Photobacterium profundum SS9] (279 aa)
Score = 360, Expect = 2.1e-32, Identities = 84/242 (34%), Positives = 141/242 (58%)
  Q:    65 QNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           + ++ K L+Q++I  A K   ++     E I+ H  YLINLG+P+           I E+ R NQ+   L+  HPGS L   + +  +  IA+++N A +    +V+  +E  AG+GS VG  FE +++I+  +++K R+GVC+DTCH   +G D+   +  + T  EF + + +S+++ +HLNDSK ++GS  DRH ++G G++G+D            N+P +LET   D   I++QEI+ L S
  S:    34 RQWVAKPLEQDVI-TAFKARCQQYGFKSEAILPHDSYLINLGNPETEKLEKSRAAFIDEMQRCNQLGLTLLNFHPGSHLKKINESDCLRLIAESINMAHQEVP-EVVAVIENTAGQGSNVGWRFEHLAEIIDQIEDKSRVGVCIDTCHTFAAGYDLRSEAATEVTFSEFDQVVGMSFLRGMHLNDSKGKLGSHLDRHHSLGEGEIGWDCFRYLMQASGFDNIPLVLETINPD---IWQQEIMMLRS 274
>gi|67613071|ref|XP_667273.1| apurinic/apyrimidinic endonuclease Apn1 [Cryptosporidium hominis TU502] >gi|54658393|gb|EAL37044.1| apurinic/apyrimidinic endonuclease Apn1 [Cryptosporidium hominis] (349 aa)
Score = 359, Expect = 2.3e-32, Identities = 96/277 (34%), Positives = 149/277 (53%)
  Q:    25 KNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP-YRDDKPIYKQEI 301
           K +  +G+HV   A   +  SV  ++   G  F +F  P + +    L Q  ID   K  +       +  + H  YLINLG+P E  RS        E+ R + +  +L   HPGS +    +  +I  I+D +NKA E T + VI  +E  A +   VG  F+E+S+I+  VK+K R+GVCLDTCH+  +G D+   +   + + EF   + L Y+K +HLNDSK +  S  DRH+N+G G +G +      ++ +  ++P ILETP   +D  +YK+EI
  S:    61 KYRKFVGAHV--SASGGVDKSVNNSMNIAGMAFSMFLKPSRGWNAPPLKQQTIDLFKKNCETNKIEYCKFCIPHGSYLINLGNPDEEKRSKMYVAFEDELKRCDALGIRLYNFHPGSTVGQCSKEESIQFISDCINKAHEQTKS-VITVLENCA-ESKCVGYRFKELSEIIERVKDKSRVGVCLDTCHLFAAGYDVRTAESFNKVMVEFEAVIGLKYLKAMHLNDSKGQFNSGLDRHENLGKGNIGMECFKFIMNDSRFNDIPLILETPDPNNDDKVYKKEI 338
>gi|170103340|ref|XP_001882885.1| predicted protein [Laccaria bicolor S238N-H82] >gi|164642256|gb|EDR06513.1| predicted protein [Laccaria bicolor S238N-H82] (302 aa)
Score = 359, Expect = 2.3e-32, Identities = 91/272 (33%), Positives = 148/272 (54%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVV-HAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP-YRDDKPIYKQEI 301
           +G+HV   A   +  +++       N F +F    + +    L +  I    K MKE       N+V+ H  YLINLG+P    R    +  + ++ R  Q+   L   HPGS + D   + +++ IA+ +N+A + T   V   +E MAG G+ +G +F  ++ I+  V++K R+GVCLDTCH   +G DI   +    TL +F   + LSY++ +HLNDSK E  S++DRH+NIG G +G        ++ ++ N+P ILETP +     ++ +EI
  S:     1 VGAHV--SAVGGVENAIVNARAIGANAFALFIKSQRKWTSPPLSEESIASFKKRMKEYG--YSPNVVLPHGSYLINLGNPDADKRKKSYDCFLDDLKRCEQLGLTLYNFHPGSTVGDCSTDESLSLIAECINQAHKETAF-VTTVLENMAGAGNIIGGDFAHLAGIIERVEDKTRVGVCLDTCHSFAAGYDIRTKEGWESTLTKFDSQVGLSYLRGMHLNDSKTEFNSKRDRHENIGLGHLGIPAFQHILNDPRVQNIPLILETPSFEKPAEVWGKEI 273
>gi|169625152|ref|XP_001805980.1| hypothetical protein SNOG_15845 [Phaeosphaeria nodorum SN15] >gi|160705609|gb|EAT76683.2| hypothetical protein SNOG_15845 [Phaeosphaeria nodorum SN15] (466 aa)
Score = 359, Expect = 2.4e-32, Identities = 80/214 (37%), Positives = 128/214 (59%)
  Q:    98 HAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKA-IEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY---------RDDKPIYKQEI--------INLNSKEWKE 311
           H  YL+NL  P  + +    +  + ++ R N +  KL   HPG+A  + R   I  IA N+N+A  +    DV+  +ETMA  G+ +G  F +++ I+  V +K R+GVCLDTCH+  +G D+  P+    T++EF   + L Y+K +H+NDSK  + S +D H NIG G +G        ++++L  +P +LETP           DDK I+ +EI        +++ S E+KE
  S:   161 HGSYLVNLAHPDPARKKQAFDSFLNDLERCNTLGIKLYNFHPGNANATTREEGIRLIAQNINEAHQDKASGDVVAVLETMASLGNTIGGTFADLADIIKLVDDKARVGVCLDTCHVFAAGYDLRTPEAYAATMKEFDDVIGLKYLKALHMNDSKAPLSSYRDLHANIGTGFLGLSSFHNIVNDKRLHGLPMVLETPVDSVDENGKKTDDKGIWAREIKMLESLVGMDIESDEFKE 395
>gi|146312402|ref|YP_001177476.1| endonuclease IV [Enterobacter sp. 638] >gi|166920084|sp|A4WCJ5|END4_ENT38 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|145319278|gb|ABP61425.1| Endonuclease IV [Enterobacter sp. 638] (285 aa)
Score = 359, Expect = 2.5e-32, Identities = 84/255 (32%), Positives = 137/255 (53%)
  Q:    57 FMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           F +FT   + +    L   +I++  K   EK       I+ H  YLINLG P +          + E+ R  Q+   L+  HPGS L   D +  +  IA+++N A+  T+  V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+    + ++T  EF + +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P +LET   D   I+ +EI  L +++  E
  S:    29 FALFTKNQRQWRAAPLTPEIIND-FKAACEKYNFGPGQILPHDSYLINLGHPVQEALDKSREAFLDELQRCEQLGLTLLNFHPGSHLMQIDEDACLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKTRVGVCIDTCHAFAAGYDLRSQEECEKTFAEFERIVGFKYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRFIMQDPRFDGIPMVLETVNPD---IWAEEIAWLKAQQTAE 282
>gi|158521891|ref|YP_001529761.1| apurinic endonuclease Apn1 [Desulfococcus oleovorans Hxd3] >gi|158510717|gb|ABW67684.1| apurinic endonuclease Apn1 [Desulfococcus oleovorans Hxd3] (283 aa)
Score = 359, Expect = 2.7e-32, Identities = 75/209 (35%), Positives = 123/209 (58%)
  Q:    93 ENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           ++I+ H  YLINLG P+             E+ R  Q+  K +  HPGS L     +  ++ IA+++N A++ T + V   +E  AG+G+ +G  FE +++++  V++K R+GVCLDTCH   +G D+   S  + TL+ F + + L Y++ +HLNDS   + SR DRH ++G G +G D   +  ++ +  N+P ILET    D  I++QEI
  S:    64 DHILPHDSYLINLGHPEADNLKKSRTAFFDEMKRCEQLGLKFLNFHPGSHLGKISEDACLSRIAESVNMALDRTAS-VCAVIENTAGQGTNLGHRFEHLARVIDQVEDKTRVGVCLDTCHTFAAGYDLRTASTYEATLKAFDRVVGLKYLRAVHLNDSIKGLASRVDRHQSLGQGALGLDVFRRIMNDRRFENMPLILET---KDATIWEQEI 272
>gi|116515028|ref|YP_802657.1| hypothetical protein BCc_087 [Buchnera aphidicola str. Cc (Cinara cedri)] >gi|116256882|gb|ABJ90564.1| endonuclease IV [Buchnera aphidicola str. Cc (Cinara cedri)] (290 aa)
Score = 358, Expect = 2.9e-32, Identities = 92/257 (35%), Positives = 145/257 (56%)
  Q:    45 SVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKY---LDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           SVL+  + +   F  F   P  +    L Q+ I    K   + N   L+ I+ H+ YLINLG P +  +      LI EIN  N +   +I +HPGS+L        + +I++++N  ++ T+N +II +E  +G+G  +G  FE ++ I++ V+NK RIGVCLDTCH+  SG  +++ +  L  F ++   + L Y++ IHLNDSK +  S+ DRH+N+GYG +      K     +  N+P ILET    D  I+K+EI
  S:    18 SVLQANKLNATAFSFFVKNPLRWNTLPLQQSTIKSFRKFCNKYNYSTLQ-ILPHSSYLINLGHPDKEKKKKSCKTLIEEINFCNLLGLVMINIHPGSSLKKITEKKCLENISNSINYILKKTNN-IIIVLENTSGQGGNMGYCFEHLAFIINKVRNKSRIGVCLDTCHLFASGYQLNNKNSFLNIFYRFHELIGLKYLRGIHLNDSKGKFNSKLDRHENLGYGNIKTSVFSKIVRVIEFNNIPIILET---KDASIWKKEI 273
>gi|50292569|ref|XP_448717.1| unnamed protein product [Candida glabrata] >gi|49528029|emb|CAG61680.1| unnamed protein product [Candida glabrata] (354 aa)
Score = 358, Expect = 2.9e-32, Identities = 91/267 (34%), Positives = 135/267 (50%)
  Q:    45 SVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEK------NPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           SV        N F +F   P+ ++     Q    E +   KE       NPL   +I+ H  Y INL +P            I ++ R  Q+   L   HPGS L  D +  +  +A  +NKA+  T   V I +E MAG G+ VG +  ++ K++  V +K RIGVC+DTCH   +G DI   D   +  ++F   +   Y+  +HLNDSK  +G+ +D H+ +G G +G D+    AH + L  +P +LETP  DD   Y +E+  L   EW E
  S:    27 SVTNAFNAGCNSFAMFLKSPRKWVSPAFTQ----EEIAKFKENCEKYGYNPL--TDILPHGQYFINLANPDPEKAEKSYESFIDDLTRCEQLGVGLYNFHPGSTLKGDHDEQLKQLASYINKALGET-KFVKIVLENMAGTGNLVGSDLTDLRKVIDMVTDKSRIGVCIDTCHTFAAGYDIQSKDAFDKFWKDFDDIIGYKYLASVHLNDSKAPLGANRDLHEKLGEGYLGLDFFRNLAHYDHLKGIPIVLETPQPDDAG-YAKEVKLL---EWLE 291
>gi|124513402|ref|XP_001350057.1| apurinic/apyrimidinic endonuclease Apn1 [Plasmodium falciparum 3D7] >gi|32482399|gb|AAK01930.2|AF326063_1 AP endonuclease 1 [Plasmodium falciparum] >gi|23615474|emb|CAD52465.1| apurinic/apyrimidinic endonuclease Apn1 [Plasmodium falciparum 3D7] (597 aa)
Score = 358, Expect = 3.0e-32, Identities = 87/210 (41%), Positives = 128/210 (60%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP-YRDDKPIYKQEIINL 304
           I+ H  YLINL +P +  R       + +I R  Q++ KL   HPGS +     +  I ++AD +NK  + T+N VII +E  AG+ + VG  FE +  I++ V +K RIGVCLDTCH   +G +I    + D  +++F   +++ Y+K +HLNDSK++IGS  DRH+NIG GK+  D       ++   N+P ILETP   +D+ IYK EI NL
  S:   377 ILPHGSYLINLANPDKEKRDKSYLSFLDDIKRCEQLNIKLYNFHPGSTVGQCTVDEGIKNVADCINKVHKETNN-VIIVLENSAGQKNSVGSKFEHLRDIINLVHDKDRIGVCLDTCHTFAAGYNIKTFENFDNVMKQFDDIVNVKYLKAVHLNDSKSDIGSGLDRHENIGKGKLTMDTFKYIMKSKYFKNIPIILETPDITNDESIYKYEIQNL 590
>gi|163846633|ref|YP_001634677.1| apurinic endonuclease Apn1 [Chloroflexus aurantiacus J-10-fl] >gi|187602548|ref|ZP_02988772.1| apurinic endonuclease Apn1 [Chloroflexus sp. Y-400-fl] >gi|189037121|sp|A9WII8|END4_CHLAA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|163667922|gb|ABY34288.1| apurinic endonuclease Apn1 [Chloroflexus aurantiacus J-10-fl] >gi|187485368|gb|EDU23345.1| apurinic endonuclease Apn1 [Chloroflexus sp. Y-400-fl] (285 aa)
Score = 358, Expect = 3.0e-32, Identities = 70/216 (32%), Positives = 121/216 (56%)
  Q:    78 DEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI-EATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           +EA     E+    +  +VVH  YLINL +P +  R   +     E+ R  Q+    +V HPG+         +  +AD + + + E    + +I +ET AG+G+ +G  FE ++++   +   +R+G+C+DTCH+  +G DI DP+    T  E  + + L+ +K  HLNDS+ ++GSR DRH +IG G +G +      ++ + A++P I+ETP  +D
  S:    47 EEATAFRTEQQRTGIHPVVVHDSYLINLAAPADELREKSIAAFADELERCAQLDIPYLVTHPGAHTGIGEEAGLARVADAICRLLAEGVGGNTMILLETTAGQGTALGYRFEHLARLFELIPYHERLGICVDTCHIFAAGYDIRDPEGYQTTFAELDRLVGLTRVKCFHLNDSQKDLGSRVDRHAHIGQGCIGVEAFRMLVNDPRFADLPMIIETPKGED 266
>gi|94268621|ref|ZP_01291237.1| Deoxyribonuclease IV (phage T4-induced) [delta proteobacterium MLMS-1] >gi|93451533|gb|EAT02350.1| Deoxyribonuclease IV (phage T4-induced) [delta proteobacterium MLMS-1] (284 aa)
Score = 358, Expect = 3.1e-32, Identities = 75/210 (35%), Positives = 116/210 (55%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEAT--DNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           +  H  YLINL   K  T       L  E+ R   +    +++HPGS L       I  +  NL++ + A   +N V I +E  AG+G+ +G +F E+++IV+G  + +R+G C DTCH   +G D+  P   +QT +EF  YL L  +   HLND+  ++GSR DRH +IG GK+G +      ++ + A  P +LET   D  P  +++I NL
  S:    64 VAAHNSYLINLAGYKPETEERSRQALTAELQRCQALGISWLIMHPGSHLGRGTKEGIERLTRNLDQVLAAVGEENRVTILLENTAGQGTNLGCDFAELAEIVAGCHHPQRLGFCFDTCHAFAAGYDLRTPAAYEQTFKEFDHYLGLDRLHFFHLNDALKDLGSRVDRHAHIGQGKIGLEGFRLLLNDPRFATHPMVLET---DKGPDLREDIENL 275
>gi|78188506|ref|YP_378844.1| endonuclease IV [Chlorobium chlorochromatii CaD3] >gi|123580266|sp|Q3AT74|END4_CHLCH Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|78170705|gb|ABB27801.1| Endonuclease IV [Chlorobium chlorochromatii CaD3] (282 aa)
Score = 358, Expect = 3.2e-32, Identities = 91/277 (32%), Positives = 146/277 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           +G+HV   A   +  + L         F +FT   + +   +L +  I EA +          ++I+ H  YLINLGSP         +  I E+ R   +  +L+  HPGS L +     ++  IA+++N A+EAT N V   +E  AG+G+ +G  FE+++ ++  +++K R+GVCLDTCH+  SG D+S     + T  EF   + L Y++ +HLND+   +GSR DRH ++G G +G        ++     +P ILETP  D   I+ +EI  L S
  S:     4 VGAHV--SASGGVEQAPLNATAIGAKAFALFTKNQRQWKAPKLSKATI-EAFQKACADGGFQPQHILPHDSYLINLGSPDPEKLERARSAFIDEMQRVADLGLQLLNFHPGSHLKEISEEASLLLIAESINMALEAT-NGVTAVIENTAGQGTNLGYRFEQIAFLIDRIEDKSRVGVCLDTCHLFASGYDLSSTEAIETTFNEFDSTVGLHYLRGMHLNDAMQPLGSRVDRHASLGKGTIGMAAFTFIMNHPACEEIPLILETPNPD---IWSEEIALLYS 277
>gi|15076900|gb|AAK82983.1|AF284763_1 apurinic/apyrimidinic endonuclease Apn1 [Plasmodium falciparum] (597 aa)
Score = 358, Expect = 3.3e-32, Identities = 87/210 (41%), Positives = 128/210 (60%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP-YRDDKPIYKQEIINL 304
           I+ H  YLINL +P +  R       + +I R  Q++ KL   HPGS +     +  I ++AD +NK  + T+N VII +E  AG+ + VG  FE +  I++ V +K RIGVCLDTCH   +G +I    + D  +++F   +++ Y+K +HLNDSK++IGS  DRH+NIG GK+  D       ++   N+P ILETP   +D+ IYK EI NL
  S:   377 ILPHGSYLINLANPDKEKRDKSYLSFLDDIKRCEQLNIKLYNFHPGSTVGQCTVDEGIKNVADCINKVHKETNN-VIIVLENSAGQKNSVGSKFEHLRDIINLVHDKDRIGVCLDTCHTFAAGYNIKTFENFDNVMKQFDDIVNVKYLKAVHLNDSKSDIGSGLDRHENIGKGKLTMDTFKYIMKSKYFKNIPIILETPDITNDESIYKYEIQNL 590
>gi|51243905|ref|YP_063789.1| endonuclease IV [Desulfotalea psychrophila LSv54] >gi|59797729|sp|Q6ASE4|END4_DESPS Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|50874942|emb|CAG34782.1| probable endonuclease IV [Desulfotalea psychrophila LSv54] (292 aa)
Score = 358, Expect = 3.5e-32, Identities = 83/258 (32%), Positives = 145/258 (56%)
  Q:    54 GNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKE---KNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID---ISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS---KEWKE 311
            N F +FT   + +  K L +    E++   KE   +  +   +++ H  YLINLG P+           + E+ R  Q+   L+  HPGS L   D    ++ IA+++N A   +  DVI  +E  AG+G+ +G  FE +++I++ V++K R+GVC+DTCH   +G D   +   +++  EF + +   Y++ +HLND+K+E  SR DRH ++G G +G++       +++  ++P ILET    D  ++++EI  L      EW+E
  S:    26 ANAFALFTKNQRQWKAKPLTE----ESIAAFKENLTEAGIEARHVLPHDSYLINLGHPEAEALEKSRGAFMDELGRCAQLGLPLLNFHPGSHLKKIDPEACLDRIAESINLA-HGSVADVITVIENTAGQGTNLGYRFEHLARIIAAVEDKSRVGVCIDTCHAFAAGYDLRTVEACEKSWAEFDRIVGFKYLRGMHLNDAKSEFFSRVDRHQSLGAGNIGWEAFRYIMKDDRFDDIPLILETV---DTSLWQEEIKKLQQWSVVEWRE 285
>gi|94264840|ref|ZP_01288616.1| Deoxyribonuclease IV (phage T4-induced) [delta proteobacterium MLMS-1] >gi|93454721|gb|EAT04982.1| Deoxyribonuclease IV (phage T4-induced) [delta proteobacterium MLMS-1] (284 aa)
Score = 357, Expect = 3.9e-32, Identities = 75/210 (35%), Positives = 116/210 (55%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEAT--DNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           +  H  YLINL   K  T       L  E+ R   +    +++HPGS L       I  +  NL++ + A   +N V I +E  AG+G+ +G +F E+++IV+G  + +R+G C DTCH   +G D+  P   +QT +EF  YL L  +   HLND+  ++GSR DRH +IG GK+G +      ++ + A  P +LET   D  P  +++I NL
  S:    64 VAAHNSYLINLAGYKPETEERSRQALTAELQRCQALGIPWLIMHPGSHLGRGTKEGIERLTRNLDQVLAAVGEENRVTILLENTAGQGTNLGCDFAELAEIVAGCHHPQRLGFCFDTCHAFAAGYDLRTPAAYEQTFKEFDHYLGLDRLHFFHLNDALKDLGSRVDRHAHIGQGKIGLEGFRLLLNDPRFATHPMVLET---DKGPDLREDIENL 275
>gi|157960898|ref|YP_001500932.1| apurinic endonuclease Apn1 [Shewanella pealeana ATCC 700345] >gi|157845898|gb|ABV86397.1| apurinic endonuclease Apn1 [Shewanella pealeana ATCC 700345] (284 aa)
Score = 357, Expect = 3.9e-32, Identities = 81/212 (38%), Positives = 129/212 (60%)
  Q:    90 LLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAIN----HIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           +  E I+ H  YLINLG P     +        E+ R  QI  KL+  HPGS L   R + I+    +I++++N A+E T N V   +E  AG+GS +G +FE++++I+ GV++K R+G+C+DTCH+  +G DI   +  +QT E F K +   Y+K +HLNDSK  + SR DRH+++G G++G +        + +  +P ILET   +   I+++EI
  S:    64 IAFEAILPHDSYLINLGHPDPELLNKSREAFYDEMQRCEQIGLKLLNFHPGSHL---RKMPIDDCLTNISESINLALERTSN-VTAVIENTAGQGSNLGHSFEQLAQIIDGVEDKTRVGICIDTCHLFAAGYDIRTKATCEQTFELFDKIVGNRYLKAMHLNDSKTPLNSRVDRHESLGQGEIGQEAFASLMKLDAVKGIPLILETVRAE---IWQEEI 275
>gi|167044441|gb|ABZ09117.1| putative AP endonuclease family 2 [uncultured marine crenarchaeote HF4000_APKG6D9] (282 aa)
Score = 357, Expect = 4.6e-32, Identities = 92/265 (34%), Positives = 143/265 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKV---GFDYLVKWAHNEKLANVPKILETPYRDDK 294
           +G HV       +  +V   +E   + F +FT  P+ +  KEL +  I      +KE     L     H PYL NL SPK       +  LI EI R +Q+    +V H GS L +     I  + + L++A   T  DV+I +E  AG+ + VG +F+++ +I + +K  K+ GVC DTCH   SG D+   +   +T +EF KY+ +  +K++HLND++ EIG   DRH ++G G +   G   ++K+A+ EK   +P ILETP   D+
  S:     6 IGCHVSISGS--IDKAVDNAVERKCSAFQIFTRNPRGWNAKELTKEDIANFKSKLKESKIERLAT-CAHMPYLPNLASPKVEGFEKSVKTLIDEIERCSQLGIPYLVTHLGSHLGTGEEGGIKRLVEGLSRA-GKTSKDVMILLENTAGQKNSVGSDFKQLGEIFNQLKPAKKFGVCFDTCHAFVSGYDLRSKEKVKETFDEFEKYVGIKNLKILHLNDARGEIGCNLDRHYHLGLGGIGEKGISAVIKFANKEK---IPIILETPIDKDR 269
>gi|82596353|ref|XP_726227.1| AP endonuclease 1 [Plasmodium yoelii yoelii str. 17XNL] >gi|23481545|gb|EAA17792.1| AP endonuclease 1 [Plasmodium yoelii yoelii] (460 aa)
Score = 356, Expect = 5.5e-32, Identities = 83/207 (40%), Positives = 123/207 (59%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP-YRDDKPIYKQEI 301
           I+ H  YLINL +P +  R       + +I R  Q++ KL   HPGS +        I +I+D +N+A + T N VII +E  AG+ + +G  FE +  I+S + +K+RIGVCLDTCH   +G DI   +   Q +  F   +D  Y+K +HLNDSK+++GS  DRH+NIG GK+  D       ++   N+P +LETP   +D+ +YK EI
  S:   239 ILPHGSYLINLANPDKEKREKSYLSFVDDIKRCEQLNIKLYNFHPGSTVGMCSTEQGIKNISDCINRAHKETSN-VIIVLENSAGQKNSIGSKFEHLRDIISQINDKERIGVCLDTCHTFAAGYDIKSYEKFEQVMNHFHNIVDSKYLKAVHLNDSKSDLGSGLDRHENIGKGKLTLDTFKYIMTSKYFKNIPIVLETPDITNDESVYKYEI 449
>gi|145219294|ref|YP_001130003.1| endonuclease IV [Prosthecochloris vibrioformis DSM 265] >gi|189037126|sp|A4SDE2|END4_PROVI Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|145205458|gb|ABP36501.1| Endonuclease IV [Prosthecochloris vibrioformis DSM 265] (279 aa)
Score = 355, Expect = 6.7e-32, Identities = 89/252 (35%), Positives = 134/252 (53%)
  Q:    57 FMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISD---PDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
           F +FT   + +    L +  +D A +   E       +I+ H  YLINLG+P            I E+ R   +   L+  HPGS L++      +  IAD++N AI+ATD  V   +E  AG+G+ +G  FE +  I+  ++++ RIGVCLDTCH+  SG D+      ++T EEF + + + Y+K +HLND+   +GSR DRH  IG G +G +       +     +P ILETP   D   +K+EI  L S E
  S:    29 FALFTRNQRQWHSPPLQKASVD-AFRRHCEAGGFDARHILPHDSYLINLGNPDPDKLERSRKAFIEEMERAETLGLVLLNFHPGSHLNAIGEEECLGLIADSINLAIKATDR-VTAVIENTAGQGTNLGSRFEHLRAIIDRIEDRSRIGVCLDTCHLFASGYDLGTAEAAERTFEEFDRTVGMQYLKGMHLNDALRPLGSRLDRHACIGKGMIGIEGFRYIMQSPLFEEIPLILETP---DSEGWKEEIELLYSLE 279
>gi|157371464|ref|YP_001479453.1| endonuclease IV [Serratia proteamaculans 568] >gi|166920086|sp|A8GGT5|END4_SERP5 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|157323228|gb|ABV42325.1| apurinic endonuclease Apn1 [Serratia proteamaculans 568] (279 aa)
Score = 355, Expect = 7.2e-32, Identities = 92/280 (32%), Positives = 153/280 (54%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL---DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
            +G+HV   A   +  +V+   E +   F +FT   + +    L  ++ID+  K    +       I+ H  YLINLG P            + E+ R  Q+   L+  HPGS L   D D+ +A   IA+++N  ++ T   V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+      +QT +E  + +  +Y++ +HLND+K+E GSR DRH ++G G +G   F Y+++   + +   +P ILET   D   I+ +EI  L +++
  S:     3 FVGAHV--SASGGVDQAVIRAHELEATAFALFTKNQRQWKAAPLPADVIDK-FKSACAQYGYGPGQILPHDSYLINLGHPVTEALEKSREAFLDEMQRCEQLGLTLLNFHPGSHLMQIDEDKCLA--RIAESINLVLDKTSG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTEETCEQTFKELGEVVGFNYLRGMHLNDAKSEFGSRVDRHHSLGEGNIGKTVFSYIMR---DPRFDKIPLILETVNPD---IWAEEIAWLKAQQ 279
>gi|187735347|ref|YP_001877459.1| apurinic endonuclease Apn1 [Akkermansia muciniphila ATCC BAA-835] >gi|187425399|gb|ACD04678.1| apurinic endonuclease Apn1 [Akkermansia muciniphila ATCC BAA-835] (277 aa)
Score = 354, Expect = 8.6e-32, Identities = 92/264 (34%), Positives = 132/264 (50%)
  Q:    30 LGSHVGFKAKNY-LVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP-DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           +G H+   AK Y  +G V   L    N F  FT  P+    K +D+  I   ++L +         ++ HAPY +N  S   S        L  ++     +   L   HPG  +       I  +AD LN  + + +   I+ +ETM+GKGSEVG  FEE++ I+  V  K ++GVCLDTCH++ +G DI +  D  LE F   L L  ++ IHLNDS     S KDRH+ IG G +G    +   ++  L  +P  LETP RDD
  S:     4 IGCHLS-SAKGYEAMGRV--ALSIGANTFQFFTRNPRGSKAKAIDEQDIARFLELARNNG---FGTLLAHAPYTLNPCSADPSVARFAAQVLKEDLELMEHLPGNLYNFHPGCHVGQGVEKGIELVADQLNDVL-SPEQKTIVLLETMSGKGSEVGRTFEELAAIMERVDLKDKLGVCLDTCHVYSAGYDIVNRLDSVLEHFDAVLGLERLRAIHLNDSMTPFSSFKDRHETIGKGSLGEQAFINIINHPVLRELPFFLETP-RDD 261
>gi|15835527|ref|NP_297286.1| endonuclease IV [Chlamydia muridarum Nigg] >gi|10719984|sp|Q9PJB8|END4_CHLMU Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|7190942|gb|AAF39706.1| endonuclease IV [Chlamydia muridarum Nigg] (288 aa)
Score = 354, Expect = 1.1e-31, Identities = 90/273 (32%), Positives = 148/273 (54%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPK----ESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNK--AIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           LLG+H    A   L  ++ E  +       +FT   + + R+ L QN+I++    + E +   L  I+ HA YL N G+P     E TR      +  EI     +    +  HPG+AL   +   ++    + ++   +  T+  +++ +ET AG+GS +G +FEE++ ++ G+K    +GVCLDTCH+  +G DIS P   +Q L+ F + + LS+++ IHLNDS   +G  KDRH  IG G +G +       +E+   +PK LETP   D  ++ +EI
  S:    11 LLGAHT--SAAGGLHNALYEGRDIGATTIQLFTANQRQWKRRSLTQNMIEQFQTALDETS---LSYIMSHAGYLNNPGAPNPEILEKTRIC----MYQEIADCIALGISFVNFHPGAALSDSKESCLDRAITSFSQMAPLFETNPPLVVLLETTAGQGSLIGSSFEELAYLIQGIKAHIPVGVCLDTCHIFAAGYDISSPEGWEQVLKHFDEVIGLSFLRAIHLNDSIFPLGKNKDRHAPIGEGCIGSESFCFLMRDERTRKLPKYLETPGGPD--LWTKEI 281
>gi|29839781|ref|NP_828887.1| endonuclease IV [Chlamydophila caviae GPIC] >gi|33301066|sp|Q824X6|END4_CHLCV Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|29834128|gb|AAP04765.1| endonuclease IV [Chlamydophila caviae GPIC] (289 aa)
Score = 354, Expect = 1.1e-31, Identities = 89/278 (32%), Positives = 143/278 (51%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND--VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           LLG+H        L  ++ E  E   +   +FT   + + R+ L  +LI+     +KE +   L  I+ HA YLIN GSP           +  EI     +    +  HPG+A++  +   ++ I  + +      +N   +++  ET AG+G+ VG NFEE+S ++  + +K  +GVC+DTCH+  +G DI+ P+   + L+ F   + LSY++  HLNDS   +G  KDRH  +G G +G +       NE    +PK LETP   D  ++ +EI  L S
  S:    11 LLGAHT--STAGGLHNAIYEGQEIGASTIQMFTANQRQWRRRPLTDSLINSFKTALKETS---LSYIMSHAGYLINPGSPNPEILEKSRICIQQEIQDCISLGINFVNFHPGAAVNDTKETCLDRIISSFSLMEPLFENSPPLVVLFETTAGQGTLVGSNFEELSYLIDNLNHKIPVGVCIDTCHIFAAGYDITSPESWKRVLKNFDDVIGLSYLRAFHLNDSMFPLGQHKDRHAPLGEGDIGIESFKFLMTNEDTRMIPKYLETPGGPD--LWAKEIRQLQS 286
>gi|156933266|ref|YP_001437182.1| endonuclease IV [Enterobacter sakazakii ATCC BAA-894] >gi|166224280|sp|A7MLL2|END4_ENTS8 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|156531520|gb|ABU76346.1| hypothetical protein ESA_01078 [Enterobacter sakazakii ATCC BAA-894] (285 aa)
Score = 353, Expect = 1.2e-31, Identities = 89/280 (31%), Positives = 142/280 (50%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKE 308
            +G+HV   A   +  +     E     F +FT   + +    L   +IDE  K    K+      I+ H  +LINLG P+           I E+ R  Q+   L+  HPGS L        ++ IA+++N A++ T+  V   +E  AG+GS +G  FE ++ I+  V++K R+GVC+DTCH   +G D+    D ++T  EF + +   Y++ +HLND+K+   SR DRH ++G G +GF             N+P ILET   D   I+ +EI  L +++
  S:     3 FIGAHV--SASGGVANAPARAAEIGATAFALFTKNQRQWRAAALTPAVIDE-FKAACRKHGYGPGQILPHDSFLINLGHPEPEALEKSRAAFIDELARCAQLGLTLLNFHPGSHLQQLSEEACLSRIAESVNIALDKTEG-VTAVIENTAGQGSNLGFRFEHLAAIIDQVEDKSRVGVCIDTCHAFAAGYDLRTEEDCEKTFAEFDRIVGFQYLRGMHLNDAKSTFASRVDRHHSLGEGNIGFTPFRWIMQQSHFDNIPLILETINPD---IWNEEIAWLKAQQ 279
>gi|119357774|ref|YP_912418.1| endonuclease IV [Chlorobium phaeobacteroides DSM 266] >gi|119355123|gb|ABL65994.1| Endonuclease IV [Chlorobium phaeobacteroides DSM 266] (284 aa)
Score = 353, Expect = 1.3e-31, Identities = 81/214 (37%), Positives = 121/214 (56%)
  Q:    93 ENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQT---LEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           E+I+ H  YLINLG+P         N  I EI R   +   ++  HPGS L+  D    +  IAD++N A+E T   V   +E  AG+GS +G +FE+++ I+  + +K R+GVCLDTCH+  SG D+   +      E F + + LS ++ +HLND+K+ +GS  DRH  IG G +G        ++     +P ILETP   D   +K+EI+ L S
  S:    64 EHILPHDSYLINLGNPDPDKLERSRNAFIDEIRRAASLGLVMLNFHPGSHLNQIDEKGCLQLIADSVNIALEKTSG-VTAVIENTAGQGSNLGNSFEQLASIIDKIDDKSRVGVCLDTCHLFASGYDLQSSEAVTAMFEAFDRTVGLSNLRGMHLNDAKHPLGSHLDRHACIGKGAIGLSAFASIMNSPFCEEIPLILETP---DAEGWKEEIVLLYS 277
>gi|89209751|ref|ZP_01188146.1| AP endonuclease, family 2 [Halothermothrix orenii H 168] >gi|89160820|gb|EAR80473.1| AP endonuclease, family 2 [Halothermothrix orenii H 168] (278 aa)
Score = 352, Expect = 1.5e-31, Identities = 84/235 (35%), Positives = 129/235 (54%)
  Q:    55 NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           N   +F   P+ +  KE+  + I +    +K++N   +  +VVH+ YLIN+ +P++      +N L  E  RT  I++   V+HPGS      +  IN I + +N       N   + +E +AG GS +G NF E+  I++ V +  RIGVCLDTCH   +G D+   D   + L +F K + L  +KVIHLNDSK  + S KD H +IG G++G   +    ++  L + P ILETP
  S:    26 NALQIFVKNPRGWKIKEVSDSEIKKLKDNIKKEN---MYPLVVHSSYLINMATPRDELWEKSVNSLKKEYKRTELINADYFVVHPGSHTGKGLHFGINRIIEAINSVFGEVKNGPQLLLENVAGAGSSIGSNFTELRDIINKVDDYARIGVCLDTCHAFAAGYDLRYEDGLEELLNDFDKIIGLDLLKVIHLNDSKYGLASNKDEHAHIGEGEIGEKGISNIINHPLLKDKPFILETP 260
>gi|161527576|ref|YP_001581402.1| apurinic endonuclease Apn1 [Nitrosopumilus maritimus SCM1] >gi|160338877|gb|ABX11964.1| apurinic endonuclease Apn1 [Nitrosopumilus maritimus SCM1] (279 aa)
Score = 352, Expect = 1.5e-31, Identities = 90/265 (33%), Positives = 141/265 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKV---GFDYLVKWAHNEKLANVPKILETPYRDDK 294
           +G HV       +  SV   +E + + F +FT  P+ +  K L ++ I      +KE           H PYL NL +PKE      +  L+ E+ R  Q+    +V H GS L +     I  +   L +A   T NDV+I +E  AG+ + VG +F+++ +I   +K  K+ GVCLDTCH    G D+   +   +T  EF KY+ +  +K++HLND+K ++G   DRH ++G G +   G   +VK+A+ +K   +P ILETP  DD+
  S:     3 IGCHVSISGS--IDKSVDNAVERECSAFQIFTRNPRGWHAKTLTKDDITNFKSKLKESKIDRFAT-CAHMPYLPNLATPKEDGFEKSVKTLVDEVERCAQLGIPYLVTHLGSHLGTGEEAGIKKLVKGLTEA-GKTKNDVMILLENTAGQKNSVGSDFKQLGEIFKQLKPAKKFGVCLDTCHAFVFGYDLRTEAKVKETFSEFDKYVGIDNLKILHLNDAKGDLGCNLDRHYHLGMGGIGEKGISAIVKFANKKK---IPIILETPIDDDR 266
>gi|86157477|ref|YP_464262.1| endonuclease IV [Anaeromyxobacter dehalogenans 2CP-C] >gi|85773988|gb|ABC80825.1| Endonuclease IV [Anaeromyxobacter dehalogenans 2CP-C] (275 aa)
Score = 351, Expect = 1.9e-31, Identities = 81/264 (30%), Positives = 140/264 (53%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDG-NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKN--KKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR 291
           +LLG+H G       V +     E DG +C  +FT   + +  K L+     + VK  + +     + +  H+ YLIN  +     R    + L  E++R  ++    ++ HPGS  ++   +A+  +A+ + +AIE       + VET AG+GS +G  FEE++ I   +    ++R GVC+DTCH+  +G D++  +   +T EE  + + LS ++  HLNDSK  +G R DRH++IG G +G     +  ++ + A +P  +ET  R
  S:     1 MLLGAHEGIAGG---VSTAFARAEADGADCLQIFTRNARGWAAKPLEP----DEVKRFQGEARRTRKPVAAHSSYLINSAAADRDLRKKSWDALADELDRCERLGIPGLIFHPGSHENAAEGIAL--VAEGMQRAIEQVPGKAKLLVETTAGQGSSLGWRFEEIAAIRQAIPGAARRRTGVCVDTCHLFAAGYDLTTEEGYHRTFEELDRVVGLSNVRAFHLNDSKKPLGCRVDRHEHIGQGAMGLGPFRRLVNDPRFAEIPGFVETESR 261
>gi|152971136|ref|YP_001336245.1| endonuclease IV [Klebsiella pneumoniae subsp. pneumoniae MGH 78578] >gi|166224282|sp|A6TBP4|END4_KLEP7 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|150955985|gb|ABR78015.1| endonuclease IV [Klebsiella pneumoniae subsp. pneumoniae MGH 78578] (284 aa)
Score = 351, Expect = 2.0e-31, Identities = 86/255 (33%), Positives = 132/255 (51%)
  Q:    57 FMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           F +FT   + +    L    I E  K   EK       I+ H  YLINLG P E       +  I E+ R  Q+   L+  HPGS L        +  IA+++N A+  T+  V   +E  AG+GS +G  FE ++ I+ GV++K R+GVC+DTCH   +G D+      ++T   F + +   Y++ +HLND+K+  GSR DRH ++G G +G D       + +   +P ILET   D   I+ +EI  L +++  E
  S:    29 FALFTKNQRQWRAAPLSDETIAE-FKAACEKYHFGPGQILPHDSYLINLGHPVEEALEKSRDAFIDEMTRCQQLGLTLLNFHPGSHLQQIPEEECLARIAESINIALAKTEG-VTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRSAEACEKTFAAFERIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDCFSWIMQDSRFDGIPLILETINPD---IWAEEIAWLRAQQIAE 282
>gi|116753721|ref|YP_842839.1| apurinic endonuclease Apn1 [Methanosaeta thermophila PT] >gi|116665172|gb|ABK14199.1| Endonuclease IV [Methanosaeta thermophila PT] (291 aa)
Score = 351, Expect = 2.1e-31, Identities = 90/265 (33%), Positives = 143/265 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY---RDDK 294
            G H+      +L  SV   +E   + + +FT  P+ +  K+L  ++I EA K    ++ +    +V H PYL NL SP+ES  S  +  L  E+ R + +    +V H GS L S R+  I+ I   +  A+  + N   I +ET +G  + +G  FE+++ ++  V     +G+CLDTCH+  +G D+ D    D TL  F     L  + +IHLNDS  ++GS  DRH++IG GK+G +      ++ +L  +P ILETP    RDD+
  S:    13 FGVHISIAGGIHL--SVRRAIELGCDTYQIFTSNPRGWHTKQLSDDVI-EAFKSQLSRSGIW--PVVGHMPYLPNLASPRESVYSRSVQALKDELMRCSALGIPYLVTHMGSHLGSGRDSGISRIVGAIEAALPDS-NGTKILLETTSGSKNSIGGRFEDLADVLERV-GSDLLGICLDTCHVFAAGYDLRDEKSLDATLRAFDSTAGLKDLMLIHLNDSVGDLGSGLDRHEHIGMGKIGLNGFAAVINDYRLRELPMILETPVDKRRDDR 276
>gi|164422508|ref|XP_957961.2| hypothetical protein NCU10044 [Neurospora crassa OR74A] >gi|157069687|gb|EAA28725.2| hypothetical protein NCU10044 [Neurospora crassa OR74A] (490 aa)
Score = 350, Expect = 2.6e-31, Identities = 91/282 (32%), Positives = 146/282 (51%)
  Q:    25 KNKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKL--MKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKA-IEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR---------DDKPIYKQEIINLNS 306
           K KL +G+HV   +   +  S+   L    N F VF    + ++   LD++   +  +L  +   +P L  +++ H  YL+NL    ++         + ++ R   +  KL   HPGS        A   IA  LN+A  E    +V+  +E M G G+ +G  FE++  I+ GV++K R+GVC+DTCH   +G D+  P   ++T++ F + + L Y+K  HLNDSK   GS +D H NIG G +G        + E +  +P +LETP           ++K I+  EI  L S
  S:   121 KRKLYIGAHV--SSAGGVQNSITNALHIGANAFAVFLKSQRKWVSPPLDRSAAADFSRLASLHGYSPSL--HVLPHGSYLVNLAQVDKAKADQAYGNFVDDLQRCATLGIKLYNFHPGSTGGEPIEEACARIASQLNRAHKEKGTGEVVTVIENMCGSGNVIGSRFEDLKMIIDGVEDKSRVGVCIDTCHAFAAGHDLRTPEAFEKTMKRFDEIVGLKYLKAFHLNDSKAPFGSCRDLHANIGTGFLGLRAFHNLMNYEAVQGLPMVLETPIEEKGADGKMVENKQIWADEIKLLES 413
>gi|118046465|ref|ZP_01515115.1| apurinic endonuclease (APN1) [Chloroflexus aggregans DSM 9485] >gi|117997037|gb|EAV11228.1| apurinic endonuclease (APN1) [Chloroflexus aggregans DSM 9485] (286 aa)
Score = 350, Expect = 2.6e-31, Identities = 70/216 (32%), Positives = 118/216 (54%)
  Q:    78 DEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI-EATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQ---TLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           +E      E+    +  ++VH  YLINL +P +  R   +     E+ R  Q+    +V HPG+         +  +AD +++ + E      +I +ET AG+G+ +G  FE ++++   +    R+GVC+DTCH+  +G DI DPD    T  E  + + L  +K  HLNDS+ ++GSR DRH +IG G +G +      ++ + A++P I+ETP  +D
  S:    47 EEMAAFQAEQQRTGIHPVIVHDSYLINLAAPADDLREKSIVAFADELERCAQLKIPYLVTHPGAHTGIGEEAGLVRVADAISRLLAEGVGGTTMILLETTAGQGTALGYRFEHLARLFELIPYHDRLGVCVDTCHIFAAGYDIRDPDTYDATFAELDRLVGLERVKCFHLNDSQKDLGSRVDRHAHIGQGCIGTEAFRLLVNDPRFAHLPMIIETPKGED 266
>gi|66814514|ref|XP_641436.1| apurinic/apyrimidinic endonuclease [Dictyostelium discoideum AX4] >gi|74844876|sp|Q966U0|END4_DICDI Endonuclease 4 homolog (Endonuclease IV homolog) (Endodeoxyribonuclease IV homolog) (Apurinic/apyrimidinic endonuclease) (AP endonuclease) (DdAPN) >gi|14278957|dbj|BAB59036.1| DdAPN [Dictyostelium discoideum] >gi|60469440|gb|EAL67433.1| apurinic/apyrimidinic endonuclease [Dictyostelium discoideum AX4] (542 aa)
Score = 350, Expect = 2.6e-31, Identities = 87/231 (37%), Positives = 138/231 (59%)
  Q:    60 FTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLE--NIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDIS---DPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILET--PY 290
           FT PP+ +    +    +D+++K  +    L  +   I+ H  Y +NLGSP +       + +I E+     +  K    HPGS L+    + +I  +A++L+  +E T  DV+  +E  AG+G+ +G  FE +  +++ VK+K R+GVCLDTCHM  +G +IS   + D   +EF K +   Y+K +HLNDSK+  GS+ DRH+NIG G +G   F YLV   ++++  N+P ILET  PY
  S:   291 FTNPPRTWKHHTVK---LDDSIKFKQSCKSLNFDVNCILPHGSYFLNLGSPNKENLQKSRDLMIHEMKNCEILGVKHFNFHPGSHLNEISESESIKIVAESLDYILERT-KDVVAVIECTAGQGTNLGYTFEHLRDMIALVKDKTRVGVCLDTCHMFAAGYNISTKSNCDVIFQEFDKVVGFKYLKGVHLNDSKSTCGSKLDRHENIGKGHIGTPCFKYLV---NDKRFQNIPMILETVGPY 525
>gi|167455437|ref|ZP_02321659.1| apurinic endonuclease Apn1 [Anaeromyxobacter dehalogenans 2CP-1] >gi|167418122|gb|EDR84821.1| apurinic endonuclease Apn1 [Anaeromyxobacter dehalogenans 2CP-1] (275 aa)
Score = 350, Expect = 2.8e-31, Identities = 80/264 (30%), Positives = 141/264 (53%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDG-NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKN--KKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR 291
           +LLG+H G       V +     E DG +C  +FT   + +  K L+     + VK  + +     + +  H+ YLIN  +     R    + L  E++R  ++    ++ HPGS  ++ + + +  +A+ + +AIE       + VET AG+GS +G  FEE++ I   +    ++R GVC+DTCH+  +G D++  +   +T +E  + + LS ++  HLNDSK  +G R DRH++IG G +G D   +  ++ + A +P  +ET  R
  S:     1 MLLGAHEGIAGG---VSTAFARAEADGADCLQIFTRNARGWAAKPLEP----DEVKRFQGEARRTRKPVAAHSSYLINSAAADRDLRKKSWDALADELDRCERLGIPGLIFHPGSHENAAQGLEL--VAEGMQRAIEKVPGKAKLLVETTAGQGSSLGWRFEEIAAIRQAIPGAARRRTGVCVDTCHLFAAGYDLTTEEGYHRTFQELDRVVGLSNVRAFHLNDSKKPLGCRVDRHEHIGQGAMGLDPFRRLVNDPRFAEIPGFVETESR 261
>gi|149177350|ref|ZP_01855955.1| Xylose isomerase-like TIM barrel [Planctomyces maris DSM 8797] >gi|148843875|gb|EDL58233.1| Xylose isomerase-like TIM barrel [Planctomyces maris DSM 8797] (285 aa)
Score = 350, Expect = 3.2e-31, Identities = 90/278 (32%), Positives = 150/278 (53%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVV-----HAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN-DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSG---IDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           LLG+H       Y   +V    E++ +C  +FT     +  K L     D+ + L +E     LE+  V     H  YLINL SPKE   +  ++ ++VE+ R   +  +  V+HPGS + S     ++ I   +++  + T+     I +ET AG+GS +G  FE+++ +++ V++  R+G+C+DTCH+  +G   I  S+   T+ E  + +    I   HLNDSK E GSRKDRH+NIG G +G +      ++    + P  LETP +D++     + IN+ +
  S:     3 LLGAHQSIAGGYY--KAVDTAAEFEMDCVQIFTKNNNQWRAKPL----TDKDINLFREH----LESTGVGRPCSHMSYLINLASPKEELWNKSIDAVVVELQRAEALGLEGAVMHPGSFVTSSEEEGLDRIVAAIDRIHQETEGFQTQIWLETTAGQGSNLGFRFEQLAYLLNQVQDGGRLGICVDTCHIFAAGYPLIKKSEYKATMSELDQVIGFDRICAFHLNDSKCEFGSRKDRHENIGRGCLGLEPFRHLLNDPVFQDRPMYLETP-KDEEDGVPLDQINMQT 278
>gi|127512016|ref|YP_001093213.1| apurinic endonuclease Apn1 [Shewanella loihica PV-4] >gi|126637311|gb|ABO22954.1| apurinic endonuclease Apn1 [Shewanella loihica PV-4] (283 aa)
Score = 349, Expect = 3.8e-31, Identities = 91/278 (32%), Positives = 149/278 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDL---SYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSK 307
           +G+HV   A   +  + L   +   N F +FT   + +    L  + ID A K   E+  +  + I+ H  YLINLG P E   +      + E+ R  Q+   L+  HPGS L+    +  +  I++++N A++ T   V   +E  AG+GS +G +FE++++I+  V++K R+GVC+DTCHM  +G D++  +   E F ++  +    Y+K +HLNDSK  + SR DRH ++G G +G D       +     +P ILET    +  I+ QEI  L S+
  S:     7 VGAHV--SAAGGIANAPLNAQKIGANAFALFTKNQRRWQSAPLCPSQID-AFKANCEQANIHPDAILPHDSYLINLGHPDEEQLARSREAFLDEMQRCEQMGLTLLNFHPGSHLNKIGIDECLARISESINLALDKTQG-VSAIIENTAGQGSNLGHSFEQLAQIIDKVEDKSRVGVCIDTCHMFAAGYDLTTLEACEESFGQFDAIVGNHYLKAMHLNDSKTPLNSRVDRHHSLGAGYIGMDAFSYIMKHPATRQIPLILETI---EPEIWPQEINWLRSQ 281
>gi|163768492|ref|ZP_02175483.1| apurinic endonuclease Apn1 [Anaeromyxobacter sp. K] >gi|196171366|gb|ACG72339.1| apurinic endonuclease Apn1 [Anaeromyxobacter sp. K] (275 aa)
Score = 349, Expect = 3.8e-31, Identities = 80/264 (30%), Positives = 140/264 (53%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDG-NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKN--KKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR 291
           +LLG+H G       V +     E DG +C  +FT   + +  K L+     + VK  + +     + +  H+ YLIN  +     R    + L  E++R  ++    ++ HPGS  ++   + +  +A+ + +AIE       + VET AG+GS +G  FEE++ I   +    ++R GVC+DTCH+  +G D++  +   +T +E  + + LS ++  HLNDSK  +G R DRH++IG G +G D   +  ++ + A +P  +ET  R
  S:     1 MLLGAHEGIAGG---VSTAFARAEADGADCLQIFTRNARGWAAKPLEP----DEVKRFQGEARRTRKPVAAHSSYLINSAAADRDLRKKSWDALADELDRCERLGIPGLIFHPGSHENAAEGLEL--VAEGMQRAIEKVPGKAKLLVETTAGQGSSLGWRFEEIAAIRQAIPGAARRRTGVCVDTCHLFAAGYDLTTEEGYHRTFQELDRVVGLSNVRAFHLNDSKKPLGCRVDRHEHIGQGAMGLDPFRRLVNDPRFAEIPGFVETESR 261
>gi|89898801|ref|YP_515911.1| endonuclease IV [Chlamydophila felis Fe/C-56] >gi|89332173|dbj|BAE81766.1| virulence factor mviN [Chlamydophila felis Fe/C-56] (320 aa)
Score = 348, Expect = 4.8e-31, Identities = 87/278 (31%), Positives = 144/278 (51%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND---VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           LLG+H        L  ++ E  E   +   +FT   + + R+ L   +++   + ++E +   L  I+ HA YLIN G+P           +  EI     +    +  HPG+A++  +   ++ I  + +  +E    D   +++  ET AG+G+ VG NFEE+  ++  +K+K  +GVC+DTCH+  +G DI+ PD   Q L  F  ++ LSY++  HLNDS   +G  KDRH  IG G +G +       ++    +PK LETP   D  ++ +EI  L S
  S:    42 LLGAHT--STSGGLQNAIYEGQEIGASTIQMFTANQRQWRRRPLTDTMVNSFKQALEETS---LSYIMSHAGYLINPGAPNPEILEKSRICIQQEIQDCISLGISFVNFHPGAAVNDTKEACLDRIVSSFS-LVEPLFEDSPPLVVLFETTAGQGTLVGSNFEELGYLIDKLKHKIPVGVCIDTCHIFAAGYDITSPDSWKQVLRNFDDHVGLSYLRAFHLNDSMFPLGQHKDRHAPIGEGDIGIESFKFLMTDKATRMIPKYLETPGGPD--LWAKEISLLQS 317
>gi|39995636|ref|NP_951587.1| endonuclease IV [Geobacter sulfurreducens PCA] >gi|59797822|sp|Q74FS7|END4_GEOSL Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|39982399|gb|AAR33860.1| endonuclease IV [Geobacter sulfurreducens PCA] (296 aa)
Score = 347, Expect = 5.8e-31, Identities = 72/202 (35%), Positives = 109/202 (53%)
  Q:    92 LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDV-IICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           L  I+ H  YLINL +P   TR   L     E+ R  ++    IV+HPG+ L       I  I +  N+ I A      +I +ET AG+G+ +G  FE+++ I++G     R  VC DTCH   +G D +  +   +   EF + + L  ++  HLNDS+  + SR DRH++IG G +G +      ++++   VPKILETP  DD
  S:    62 LHEIIAHDIYLINLAAPPGETRDKSLAAFREEMERCTRLGIGTIVMHPGAHLGDGEETGIRRICEAFNRLIPAVPEFTGVILLETTAGQGTSLGHTFEQLAAIIAGTAFPDRFAVCFDTCHTFAAGYDFTTGEGYRRVFAEFDRLIGLDRLRCFHLNDSRKGLNSRVDRHEHIGRGTLGLEPFRFLMNDDRFTTVPKILETPKGDD 267
>gi|78186316|ref|YP_374359.1| endonuclease IV [Pelodictyon luteolum DSM 273] >gi|123583435|sp|Q3B5R5|END4_PELLD Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|78166218|gb|ABB23316.1| Endonuclease IV [Pelodictyon luteolum DSM 273] (279 aa)
Score = 347, Expect = 6.4e-31, Identities = 72/201 (35%), Positives = 117/201 (58%)
  Q:    92 LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRD 292
           + +I+ H  YLINLG+P            I E+ R   +  +L+  HPGS L+ S  +  +  IAD++N A+E + + V   +E  AG+G+ +G  FE+++ ++    +K R+GVCLDTCH+  +G D++  D   +T  EF + + + Y++ +HLND+ + +GSR DRH  +G GK+G D       +     +P ILETP  D
  S:    63 MRHILPHDSYLINLGNPDPLKLERSRAAFIDEMQRAESLGLELLNFHPGSHLNLSTPDECLRRIADSINMALEHS-SCVTAVIENTAGQGTNLGNRFEQLAALIEMTDDKSRVGVCLDTCHLFAAGYDLATADAAGETFREFDRVVGMRYLRGMHLNDALHPVGSRLDRHACVGKGKIGLDAFRLVMQSPAFEEIPLILETPDSD 266
>gi|194334509|ref|YP_002016369.1| apurinic endonuclease Apn1 [Prosthecochloris aestuarii DSM 271] >gi|194312327|gb|ACF46722.1| apurinic endonuclease Apn1 [Prosthecochloris aestuarii DSM 271] (283 aa)
Score = 347, Expect = 6.8e-31, Identities = 76/208 (36%), Positives = 123/208 (59%)
  Q:    94 NIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQ---TLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           +I+ H  YLINLGSP  +           E+ R   +   L+  HPGS L ++  +  +N IA+++N A++ +   V   +E  AG+GS +G  FE+++ I+  +++K R+GVCLDTCH+  +G D+   +    T  EF   + LSY++ +HLND+K ++GS++DRH++IG G +G D       +     +P ILETP  D   I+ +EI
  S:    65 HILPHDSYLINLGSPDPAKLERSRKAFTDEMQRVEALGLSLLNFHPGSHLNETGIDNCLNTIAESVNIALDNSSG-VTAVLENTAGQGSNLGHTFEQLAAIIDQIEDKTRVGVCLDTCHLFAAGYDLRTSEAVEATFNEFDSIVSLSYLRGMHLNDAKLDLGSKRDRHESIGSGFIGNDGFAAIIQHPACDEIPLILETPNPD---IWNREI 272
>gi|15605356|ref|NP_220142.1| endonuclease IV [Chlamydia trachomatis D/UW-3/CX] >gi|76789364|ref|YP_328450.1| endonuclease IV [Chlamydia trachomatis A/HAR-13] >gi|123606723|sp|Q3KL70|END4_CHLTA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|8928094|sp|O84630|END4_CHLTR Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|3329072|gb|AAC68229.1| Endonuclease IV [Chlamydia trachomatis D/UW-3/CX] >gi|76167894|gb|AAX50902.1| endonuclease IV [Chlamydia trachomatis A/HAR-13] (288 aa)
Score = 345, Expect = 1.1e-30, Identities = 91/273 (33%), Positives = 148/273 (54%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPK----ESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND--VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           LLG+H    A   L  ++ E  +       +FT   + + R+ L Q ++D+    + E +   L  I+ HA YL N G+P     E TR + ++Q   EI     +    +  HPG+AL   +   ++    + ++     +N+  +++ +ET AG+GS +G +FEE++ ++ G+K    IGVCLDTCH+  +G DIS     +Q L+ F   + LS+++ IHLNDS   +G  KDRH  IG G +G D       +E+   +PK LETP   D  ++ +EI
  S:    11 LLGAHT--SAAGGLHNALYEGRDIGATTVQLFTANQRQWKRRTLTQEMVDQFRIALNETS---LSYIMSHAGYLNNPGAPNPEILEKTR-VCMHQ---EIADCISLGISFVNFHPGAALSDSKESCLDRTIASFSQMAPLFENNPPLVVLLETTAGQGSLIGSSFEELAYLIQGIKAHIPIGVCLDTCHIFAAGYDISSVAGWEQVLKHFDAVIGLSFLRAIHLNDSVFALGKNKDRHAPIGEGCIGSDSFCFLMQDERTRMLPKYLETPGGPD--LWTKEI 281
>gi|90407203|ref|ZP_01215390.1| Endonuclease IV [Psychromonas sp. CNPT3] >gi|90311626|gb|EAS39724.1| Endonuclease IV [Psychromonas sp. CNPT3] (280 aa)
Score = 344, Expect = 1.3e-30, Identities = 89/255 (34%), Positives = 145/255 (56%)
  Q:    57 FMVFTGPPQNFMRKELDQNLIDE---AVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAIN----HIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
           F +FT   + +  K LD++ I +   A KL         E I+ H  YLINLG P+           + E+ R  Q+   L+  HPGS L   + + +N     I++++N A+E T+N V   +E  AG+G+ +G  FE+++ I+  V++K R+G+CLDTCH   SG D+      + T + FS  +   Y+  +H+NDSK  +GSR DRH ++G G++G   F+Y++K   + +   +P +LET   D   I+  EI  L  ++W +
  S:    29 FALFTKNQRRWEAKPLDEDSIKKFKAACKLYGYS----AEQILPHDSYLINLGHPEVEPLEKSRLAFVDEMQRCQQLGLTLLNFHPGSHL---KKIPVNDCLLRISESINWALERTEN-VKAVIENTAGQGTNLGYKFEQLATIIEHVEDKSRVGICLDTCHTFVSGYDLRTTQTCEDTFQAFSDIVGFEYLSAMHINDSKVPLGSRVDRHASLGVGEIGWPCFEYIMK---DSRFDAIPMVLETSNPD---IWADEIRQL--QQWAK 280
>gi|167623052|ref|YP_001673346.1| apurinic endonuclease Apn1 [Shewanella halifaxensis HAW-EB4] >gi|167353074|gb|ABZ75687.1| apurinic endonuclease Apn1 [Shewanella halifaxensis HAW-EB4] (284 aa)
Score = 344, Expect = 1.4e-30, Identities = 81/212 (38%), Positives = 125/212 (58%)
  Q:    92 LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAIN----HIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIIN 303
           LE+I+ H  YLINLG P +            E+ R  QI   L+  HPGS L   R + I+     I++++N A+E +   V   +E  AG+GS +G +FE++++I++GV++K R+GVC+DTCH+  +G DI   +   QT + F K +   Y+K +HLNDSK  + SR DRH+++G G++G          + +  +P ILET     +P   QE IN
  S:    66 LESILPHDSYLINLGHPDDELLEKSRQAFYDEMQRCEQIGLSLLNFHPGSHL---RKIPIDDCLAKISESINLALERSSG-VTAVIENTAGQGSNLGHSFEQLAQIINGVEDKSRVGVCIDTCHLFAAGYDIRTQEACKQTFDLFDKVVGNQYLKAMHLNDSKTALNSRVDRHESLGQGEIGQQAFASLMKLDVIKGIPLILETI----RPEIWQEEIN 276
>gi|114776757|ref|ZP_01451800.1| endonuclease IV [Mariprofundus ferrooxydans PV-1] >gi|114552843|gb|EAU55274.1| endonuclease IV [Mariprofundus ferrooxydans PV-1] (281 aa)
Score = 344, Expect = 1.6e-30, Identities = 85/272 (31%), Positives = 143/272 (52%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLL---LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNV-AINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           +G+HV   A   +  + L   E     F +FT   + ++ K L     DE++   K    L     E+++ H  YLINLG P+    +      + E+ R  Q+  KL+  HPGS L        ++ IA+++N  + A  + V   +E  +G+GS +G  FE ++ I+  V++K R+GVCLDTCH   +G D+  P   + T  EF   +   Y+  +H+N SK +  SR DRH ++  G++G D      ++++  ++P +LET    D+ I+ +EI
  S:     4 IGAHV--SAAGGVENAPLRAKEIGARAFALFTKNQRQWVAKPL----TDESIAAFKANLQLADIRPEHVLPHDSYLINLGHPEAEALAKSRAAFLDEMQRCEQLGLKLLNFHPGSHLKQISEADCLSRIAESINLTL-AQSSGVTAVIENTSGQGSNLGFRFEHLAAIIEQVEDKSRVGVCLDTCHTFTAGYDLRTPADCESTFGEFDDIVGFQYLSAMHINGSKAKFASRVDRHHSLTQGELGLDVFRHIMNSDQFNDIPMVLETI---DETIWPEEI 272
>gi|157374318|ref|YP_001472918.1| deoxyribonuclease IV (phage-T(4)-induced) [Shewanella sediminis HAW-EB3] >gi|157316692|gb|ABV35790.1| Deoxyribonuclease IV (phage-T(4)-induced) [Shewanella sediminis HAW-EB3] (286 aa)
Score = 343, Expect = 2.0e-30, Identities = 88/281 (31%), Positives = 150/281 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWK 310
           +G+HV   A   +  + +   +   N F +FT   + +    L Q  I++     ++ N +    I+ H  YLINLG P              EI R  Q+   L+  HPGS L   + +  ++ I+ ++N A+E +   V   +E  AG+GS +G +FE++++I+ GV++K R+G+C+DTCHM  +G D++      ++ E F + +   Y+K +HLNDSK  + SR DRH+++G G +G +      + E   N+P +LET   D   I++ EI  L S  ++
  S:     7 IGAHV--SAAGGIENAPINAKKIGANAFALFTKNQRRWQAAPLAQANIEQFKDNCRQAN-IPGSAILPHDSYLINLGHPDNIQLDKSREAFFDEIERCEQLGLSLLNFHPGSHLRKIEIDECLSRISQSINMALERS-TGVTAVIENTAGQGSNLGHSFEQLAQIIDGVEDKSRVGICIDTCHMFAAGYDLTTKAACQESFELFDRIVGNQYLKAMHLNDSKTPLNSRVDRHESLGLGHIGQEAFSFLMNLEATKNIPMVLETINSD---IWEDEINWLRSLSYE 284
>gi|157364640|ref|YP_001471407.1| apurinic endonuclease Apn1 [Thermotoga lettingae TMO] >gi|157315244|gb|ABV34343.1| apurinic endonuclease Apn1 [Thermotoga lettingae TMO] (283 aa)
Score = 342, Expect = 2.5e-30, Identities = 85/258 (32%), Positives = 133/258 (51%)
  Q:    49 TLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           T+E  GN F +F+  P+ + R  L      E  K+   K  +  +N   H  YLINL SPKE   +  +  +I+E      +    + +HPGS   S     +  I   +++ ++ T N + + +E ++ KG  +G    ++ +I+  V    RIGV  DTCH  D+G DI+  +   + L+E      L  +K+IHLNDSK   G   DRH+NIG G +G +    +    ++ +VP ILETP  D K +YK EI ++ S
  S:    21 TVEIGGNAFQIFSHSPRTW-RAGLPSKESCEKFKIFMNKCAIPFQNAFCHTGYLINLASPKEDIWTKSVQLMIIEGKICEMLGIPYLNVHPGSHTGSGEREGMQRIVRAIDEFMKNTSN-ITLLLENVSPKGGNIGYKMHQLGQIIKSVSYPDRIGVTYDTCHGFDAGYDITTKEGVTKLLDEMESAFGLWRLKMIHLNDSKAPFGKPLDRHENIGKGYIGDEGFRNFLSFSQIQSVPWILETP--DSKDLYKTEIKHVKS 277
>gi|167043357|gb|ABZ08060.1| putative AP endonuclease family 2 [uncultured marine crenarchaeote HF4000_ANIW141O9] (279 aa)
Score = 342, Expect = 2.5e-30, Identities = 86/265 (32%), Positives = 136/265 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQ---TLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK 294
           +G HV       +  +V   +E + + F +FTG P+ +  K+L    +    K + E +       V H PYL NL +P   +    +  +I E+ R  +I    +V H GS   S     I  +   L + +  T NDV I +E  AG+ + VG +F ++++I   ++   R G+C+DTCH   +G D+ +      T E+F K + L ++K++HLNDSK E+GS  DRHD+IG G++G   L K         +P ILETP  D +
  S:     3 IGLHVSISGS--IANAVTNAIERECSAFQIFTGNPRGWYTKDLANEDVRNYKKNLSECDIDRFAT-VAHMPYLPNLSTPDIPSHEKSIKAMIREVERCAKIGIPYLVTHLGSHKGSGEENGIQRLTSALME-VAKTTNDVTILLENTAGQKNSVGSDFIQLAEIFFSLEPADRFGICIDTCHTFAAGYDLKNQKNVKDTFEKFDKEIGLKHLKILHLNDSKGELGSHLDRHDHIGLGQIGNAGLSKVIKLMNKNKIPIILETPIDDRR 266
>gi|163750639|ref|ZP_02157876.1| endonuclease IV [Shewanella benthica KT99] >gi|161329634|gb|EDQ00625.1| endonuclease IV [Shewanella benthica KT99] (285 aa)
Score = 341, Expect = 3.4e-30, Identities = 89/277 (32%), Positives = 150/277 (54%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDL---SYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           +G+HV   A   +  + +   +   N F +FT   + +    L Q  I+   +     N +  + I+ H  YLINLG P              E+ R  Q+   L+  HPGS L   + +  ++ I+D++N A+E + + V   +E  AG+GS +G +FE++++I+ GV++K R+G+CLDTCHM  +G D++  +     F  + D+    Y+K +HLNDSK  + SR DRH+++G G +G   F +++     ++   +P +LET   D   I+ QEI  L S
  S:     7 IGAHV--SAAGGIQNAPINAKKIGANAFALFTKNQRRWQAAPLTQEQIESFKRNCLAAN-ISSDGILPHDSYLINLGHPDAEQLEKSRLAFFEEMQRCEQMGLTLLNFHPGSHLRKIEIDECLSRISDSINMALERS-SQVTAVIENTAGQGSNLGHSFEQLAQIIQGVEDKTRVGICLDTCHMFAAGYDLTTEEACQHSFKLFDDIVGDKYLKAMHLNDSKTPLNSRVDRHESLGLGHIGQAAFGFIMNHPATKR---IPMVLETINAD---IWPQEINWLRS 280
>gi|166154840|ref|YP_001654958.1| endonuclease IV [Chlamydia trachomatis 434/Bu] >gi|166155715|ref|YP_001653970.1| endonuclease IV [Chlamydia trachomatis L2b/UCH-1/proctitis] >gi|165930828|emb|CAP04326.1| endonuclease IV [Chlamydia trachomatis 434/Bu] >gi|165931703|emb|CAP07280.1| endonuclease IV [Chlamydia trachomatis L2b/UCH-1/proctitis] (288 aa)
Score = 341, Expect = 3.5e-30, Identities = 91/273 (33%), Positives = 147/273 (53%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPK----ESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND--VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           LLG+H    A   L  ++ E  +       +FT   + + R+ L Q ++D+    + E +   L  I+ HA YL N G+P     E TR + ++Q   EI     +    +  HPG+AL   +   ++    + ++     +N   +++ +ET AG+GS +G +FEE++ ++ G+K    IGVCLDTCH+  +G DIS     +Q L+ F   + LS+++ IHLNDS   +G  KDRH  IG G +G D       +E+   +PK LETP   D  ++ +EI
  S:    11 LLGAHT--SAAGGLHNALYEGRDIGATTVQLFTANQRQWKRRALTQEMVDQFRIALNETS---LSYIMSHAGYLNNPGAPNPEILEKTR-VCMHQ---EIADCISLGISFVNFHPGAALSDSKESCLDRAITSFSQMAPLFENHPPLVVLLETTAGQGSLIGSSFEELAYLIQGIKALIPIGVCLDTCHIFAAGYDISSVAGWEQVLKHFDAVIGLSFLRAIHLNDSVFALGKNKDRHAPIGEGCIGSDSFCFLMQDERTRMLPKYLETPGGPD--LWTKEI 281
>gi|186460256|ref|ZP_02970557.1| apurinic endonuclease Apn1 [bacterium Ellin514] >gi|184203280|gb|EDU00338.1| apurinic endonuclease Apn1 [bacterium Ellin514] (268 aa)
Score = 340, Expect = 3.7e-30, Identities = 72/202 (35%), Positives = 112/202 (55%)
  Q:    92 LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND-VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           L +I  H  YLINLG+     R   +  L+ EIN    +    +V+HPG+ L +    AI  IA  L++A +AT +  V I +E  AG+G+ +G     +++I   V   +R+GVCLDT H  ++G D+  P   +  + E   ++ +  +   HLNDSK ++GSR DRH  IG GK+G +      ++E+  ++P  LETP   D
  S:    46 LASIFGHTGYLINLGAQASENREKSIKSLVQEINMATDLGLPFLVMHPGAHLGTGEEAAIKQIAAGLDEAFQATKHSPVRIALENTAGQGTCLGHEIRHLAEIFQKVNRPERLGVCLDTAHFFEAGYDLRTPKGWNAAIGEVENFIGVKQVLAFHLNDSKTDLGSRVDRHAGIGEGKIGREAFRHIVNDERFRDLPGCLETPKSAD 251
>gi|62184659|ref|YP_219444.1| endonuclease IV [Chlamydophila abortus S26/3] >gi|81313155|sp|Q5L798|END4_CHLAB Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|62147726|emb|CAH63470.1| putative endonuclease IV [Chlamydophila abortus S26/3] (289 aa)
Score = 340, Expect = 3.9e-30, Identities = 88/278 (31%), Positives = 142/278 (51%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND---VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           LLG+H        L  ++ E  E   +   +FT   + + R+ L  +LI+     ++E +   L  I+ HA YLIN G+P           +  EI     +    +  HPG+A++  +   ++ I  + +  +E    D   +++  ET AG+G+ VG  FEE+  ++  +K+K  +GVC+DTCH+  SG DI+ P    Q L+ F   + LSY++  HLNDS   +G  KDRH  +G G +G +       +E    +PK LETP   D  ++ +EI  L S
  S:    11 LLGAHT--STSGGLQNAIYEGQEIGASTVQMFTANQRQWRRRPLTDDLINSFKTALEETS---LSYIMSHAGYLINPGAPNPEILEKSRICIQQEIQDCLSLGITFVNFHPGAAVNDTKEACLDRIVSSFS-LVEPLFEDSPPLVVLFETTAGQGTLVGSTFEELGYLIDKLKHKIPVGVCIDTCHIFASGYDITSPGSWKQVLKNFDDAIGLSYLRAFHLNDSMFPLGKHKDRHAPLGEGDIGMESFKFLMTDELTRMIPKYLETPGGPD--LWTKEIRQLKS 286
>gi|169824415|ref|YP_001692026.1| endonuclease IV [Finegoldia magna ATCC 29328] >gi|167831220|dbj|BAG08136.1| endonuclease IV [Finegoldia magna ATCC 29328] (277 aa)
Score = 340, Expect = 4.1e-30, Identities = 87/257 (33%), Positives = 137/257 (53%)
  Q:    45 SVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           ++ + LE + + F  F   P+    + + +  ID+ ++L K  N   +  IV H  Y +NL S +E  R L +  +  ++ +   +     VLHPGS  +      +  I + +NK      N  +IC+ETM+GKGSE+G + ++++ I++       + VC+DTCH+  SGI + + D  L+EF K + +  IKVIH NDS    G+ KDRH+  G G +G   L     NE+L + P ILETP  +D   YK EI
  S:    17 TIEQCLEINADTFQFFPRNPRGSKSRLIPKKEIDKFLELRKIHN---INKIVCHGAYTMNLCSDREDLRKLAVKLINEDMKKIQDMRINHYVLHPGSHKNQGIEEGLKLIVEGINKV--DVSNGQMICIETMSGKGSELGCDIDQIAYIINNASIP--LYVCIDTCHLFSSGIRLDNFDDYLDEFDKKIGIDKIKVIHCNDSMMPFGANKDRHEKFGKGLIGEQDLFNVIFNERLKDRPIILETP--NDLDGYKIEI 264
>gi|170725635|ref|YP_001759661.1| apurinic endonuclease Apn1 [Shewanella woodyi ATCC 51908] >gi|169810982|gb|ACA85566.1| apurinic endonuclease Apn1 [Shewanella woodyi ATCC 51908] (289 aa)
Score = 340, Expect = 4.2e-30, Identities = 91/263 (34%), Positives = 148/263 (56%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKEL-DQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEE----FSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGY---GKVGFDYLVKWAHNEKLANVPKILETPYRD 292
           +G+HV   A   +  + +   +   + F +FT   + +    L  Q +ID   K   ++  +L E I+ H  YLINLG P +            E+ R  Q+   L+  HPGS L   + +  ++ I+ ++N A++ T + V   +E  AG+GS +G +FE++++I+ GV++K R+GVC+DTCHM  +G DIS   Q  EE    F + +   Y+K +HLNDSK  + SR DRH+++G    GK GF++++     E   N+P +LET   D
  S:     7 VGAHV--SASGGIANAPINAKKIGADAFALFTKNQRRWQAAPLCPQQVID--FKQNCQEANILSEAILPHDSYLINLGHPDQEQLEKSRLAFFDEMERCEQMGLSLLNFHPGSHLRKIEIDECLSRISQSINMALDKTQH-VTAVIENTAGQGSNLGHSFEQLAQIIDGVEDKSRVGVCIDTCHMFAAGYDISTY-QACEESFALFDRIVGDRYLKAMHLNDSKTPLNSRVDRHESLGLGHIGKEGFEFIMNHPATE---NIPMVLETINSD 269
>gi|189426628|ref|YP_001953805.1| apurinic endonuclease Apn1 [Geobacter lovleyi SZ] >gi|189422887|gb|ACD97285.1| apurinic endonuclease Apn1 [Geobacter lovleyi SZ] (281 aa)
Score = 337, Expect = 8.0e-30, Identities = 70/202 (34%), Positives = 108/202 (53%)
  Q:    92 LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEAT-DNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           L  ++ H  YLINL +P   TR   L     E+    ++    IV+HPGS         +  +    ++  E T + + ++ +ET AG+G+ +G  FEE+  I++G K   R G+C DTCH   +G + + P+     + +F + L L  +   H NDSK  +GSR DRH++IG G +G +      H+ +   VPKILETP  DD
  S:    62 LHEVISHDIYLINLAAPAGDTRDKSLAAFGDEMATCARLGINKIVMHPGSHTTDSPEAGLERVISAFDQLFEQTPEYEGLVLLETTAGQGTNLGRTFEELQTIINGSKYPDRFGICFDTCHTFAAGYNTATPEGYADVMAQFDRLLGLERLLCFHFNDSKKGLGSRVDRHEHIGQGTLGLEPFRFIMHDPRFITVPKILETPKGDD 267
>gi|16081940|ref|NP_394350.1| endonuclease IV related protein [Thermoplasma acidophilum DSM 1728] >gi|24636842|sp|Q9HJS3|END4_THEAC Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|10640168|emb|CAC12020.1| endonuclease IV related protein [Thermoplasma acidophilum] (281 aa)
Score = 337, Expect = 8.3e-30, Identities = 81/213 (38%), Positives = 122/213 (57%)
  Q:    78 DEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLD----LSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY 290
           DEA     E     +E+ ++HA YLINL S         +     EI+R++++ S  + +HPGS  + DR   I  + D L+      D+ VII +E  AG+G+ +G   +EV+KI+    + K++GVC+DTCH   SG D+ D   +LE+F + LD    L  I   HLND+K E+GSR DRH+ IG G +    L+    +++L   PKI+ETP+
  S:    58 DEAAAFKSEVRKYGIESTMIHASYLINLASADPDLYKRSMEAFHDEIDRSDKLGSTFLTVHPGS--NPDRADGIRRVRDALST---IGDHAVIILIENTAGQGNVIGTRLDEVAKIID--TSDKKLGVCIDTCHAWASGYDLRD---SLEKFIESLDYTIGLDRIFAFHLNDAKREMGSRIDRHELIGKGTID-GGLINLIRDDRLRAKPKIMETPF 263
>gi|153896370|ref|ZP_02016948.1| apurinic endonuclease Apn1 [Halorubrum lacusprofundi ATCC 49239] >gi|151584991|gb|EDN48420.1| apurinic endonuclease Apn1 [Halorubrum lacusprofundi ATCC 49239] (291 aa)
Score = 337, Expect = 1.0e-29, Identities = 84/253 (33%), Positives = 136/253 (53%)
  Q:    42 LVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLEN-IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATD--NDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK 294
           +  +V    ++ GNC  +FT  PQ +     D N+ DE  +  +E     LE   V+H  YL+NL +PKE  R   L+ +  E++  + +    + +H G+         +    DN    I+  D  + V I +E+ AG G+++G  FE ++ I+   + +  I VC+DT H   +G D+S P   D+T+ EF   + L ++K IHLNDSK+  G+ KD H +IG G +G D + ++ ++  L +VP  LETP  D K
  S:    28 IANAVFRQKQFGGNCGQIFTHSPQVWQ----DPNIGDEEAERFREGTERDLEGPWVIHTSYLVNLCTPKEGLREKSLDSMQKEVDAADTLGIPYVNVHLGA----HTGAGVEGGLDNAASVIDDIDVPDGVTILIESDAGAGTKLGGEFEHLAGIID--RTETDIDVCVDTAHAFAAGYDLSTPEAVDETIAEFDDVVGLEHLKYIHLNDSKHACGTNKDEHAHIGEGLIGEDGMERFLNHPDLIDVPLALETPTEDGK 276
>gi|156088627|ref|XP_001611720.1| apurinic endonuclease (APN1) family protein [Babesia bovis] >gi|154798974|gb|EDO08152.1| apurinic endonuclease (APN1) family protein [Babesia bovis] (374 aa)
Score = 337, Expect = 1.0e-29, Identities = 91/274 (33%), Positives = 146/274 (53%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMK---EKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQ---TLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP-YRDDKPIYKQEI 301
           L +G+H+       L  SV+      G  F +F        R+     L D  VK      EK    +  ++ H  YLIN+ +P    R    +  + +I R  ++   L   HPGS +   ++   I +IA+ +N A++ T +  I+ +E  AG+ + +G  FE++  I++ V+NK R+ VCLDTCH+  +G DI   D+    +  F + + L Y+  +HLND K+++GS  DRH+NIG GK+  +     A++    N+P ILETP    D+ IYKQE+
  S:    84 LYIGAHI--STAGGLDNSVINAYNICGQAFALFL----KNQRRWDSPPLADATVKKFTANIEKYKYDIRYVLPHGSYLINIANPDYEKRMKSYHHFVDDIQRCEKLGITLYNFHPGSTVGMCEKPEGIRNIANCINMAMKETSSAKIV-LENAAGQKNVIGSTFEDLRDIINLVENKDRVAVCLDTCHLFAAGYDIRTKDKFEAVMRSFDEIIGLKYLVAVHLNDCKSDLGSGLDRHENIGIGKLTRETFEFIANSGYFRNMPIILETPDIHGDETIYKQEV 358
>gi|34558061|ref|NP_907876.1| endonuclease IV [Wolinella succinogenes DSM 1740] >gi|39930918|sp|Q7M8B4|END4_WOLSU Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|34483779|emb|CAE10776.1| ENDONUCLEASE IV [Wolinella succinogenes] (282 aa)
Score = 337, Expect = 1.0e-29, Identities = 88/280 (31%), Positives = 154/280 (55%)
  Q:    27 KLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           K  +G+HV   A   +  + L   +     F +FT   + +  K L++  I++    +K    +    ++ H  YLINLG P E+  +      + E+ R  Q+    +  HPGS L +   +  ++ +A+++N A+EAT   VI  +E  AG+GS VG +F  + +I+  V +K R+G+C+DTCHM  +G DI      + ++    + +   Y+K +HLNDSK +  SR DRH ++G G++G   F++++   ++ ++  +P ILET    D+ ++ QEI  L S
  S:     2 KKFVGAHV--SASGGVRNAPLNAQKIGAKAFALFTKNQRQWSAKALEEEEIEQFKANLKAAG-IAPSCVLPHDSYLINLGHPGEAELAKSREAFLDEMRRCEQLGLDRLNFHPGSHLGAISESECLSRVAESINLALEATSG-VIAVIENTAGQGSNVGYDFRHLGEIIDQVHDKSRVGICIDTCHMFSAGYDIRTREAYEASMAILDREVGWCYLKGMHLNDSKVKFQSRVDRHHSLGMGELGIAPFEFIM---NDPRMDGIPLILETI---DEALWAQEITLLYS 278
>gi|78224187|ref|YP_385934.1| endonuclease IV [Geobacter metallireducens GS-15] >gi|78195442|gb|ABB33209.1| Endonuclease IV [Geobacter metallireducens GS-15] (285 aa)
Score = 336, Expect = 1.1e-29, Identities = 77/229 (33%), Positives = 119/229 (51%)
  Q:    78 DEAVKLMKEK-NPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDV-IICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           D  V L +EK     L  I+ H  YLINL +P+  TR   L     E+ R  ++    IV+HPG+ +       I  I +  +  I A       I +ET AG+G+ +G  FE +  I+ G  +  R  VC DTCH   +G DI+ P+   Q   +F + + +  ++  H+NDSK  +  R DRH++IG G +G +      ++ + A VPKILETP  D+      +++NL +
  S:    46 DSDVALFREKWAESGLHEIICHDIYLINLAAPEGETRDKSLLSFREEMERCARLGIDKIVMHPGAHVGDGEETGIKRICEAFDALIPAVPEFTGKILLETTAGQGTNLGYTFEHLRAIIDGSAHPDRFAVCYDTCHTFAAGYDITTPEGYKQVFADFDRIIGIDRLQCFHINDSKKGLNCRVDRHEHIGQGAMGLEGFRTLVNDPRFAKVPKILETPKGDNDEF---DVMNLKT 276
>gi|152990035|ref|YP_001355757.1| endonuclease IV [Nitratiruptor sp. SB155-2] >gi|166224289|sp|A6Q1P1|END4_NITSB Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|151421896|dbj|BAF69400.1| endonuclease IV [Nitratiruptor sp. SB155-2] (281 aa)
Score = 335, Expect = 1.6e-29, Identities = 75/209 (35%), Positives = 119/209 (56%)
  Q:    93 ENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           ++I+ H  YLINLG P+E  R   L   + E+ R  Q+    +  HPGS L        ++ IAD +N+ +  +   V + +E  AG+GS +G  FE +  ++    +K R+GVCLDT HM  +G DI      D+T++ F + +   Y+K +H+NDSK +  SR DRH ++G G++G D      ++ +L ++P ILET    D  I+ +EI
  S:    65 KHILPHDSYLINLGHPEEEKRQKSLEAFLDEVRRCEQLGLDKLNFHPGSHLKKISEEECLDRIADAMNETLRQSSG-VTLVIENTAGQGSNLGYKFEHLRYLIDKSIDKSRVGVCLDTAHMFAAGYDIRTKEAYDKTMQAFDEIVGFEYLKGMHINDSKAKFASRVDRHHSLGKGEIGLDAFRFIMNDPRLDDIPLILETI---DDTIWDKEI 273
>gi|118578893|ref|YP_900143.1| apurinic endonuclease Apn1 [Pelobacter propionicus DSM 2379] >gi|118501603|gb|ABK98085.1| Endonuclease IV [Pelobacter propionicus DSM 2379] (283 aa)
Score = 335, Expect = 1.6e-29, Identities = 77/221 (34%), Positives = 120/221 (54%)
  Q:    73 DQNLIDEAVKLMKEKNPLL-LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIA---DNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           ++ L D  V L +EK     L  ++ H  YLINL S     R   L     E+    ++    +V+HPGS L      A+  ++   D L + +      V++  ET AG+G+ +G NF+E+  I+ G +  +R GVC DTCH   +G DI+  +    T EEF + + L  ++  H NDS+  +GSR DRH++IG G +G +      ++++ A  PKILETP  D+
  S:    42 EKTLSDADVALFREKFAASGLREVISHDIYLINLASAPGEVRDKSLAAFRDELETCARLGIDRVVMHPGSHLSDSPEAALTRVSQAFDRLFQEVPLFQGRVLL--ETTAGQGTNLGRNFQELRTIIDGCRYPERFGVCFDTCHTFAAGYDITSEEGYRSTKEEFDQIIGLDRLECFHFNDSRKGLGSRVDRHEHIGQGMLGLNPFRFILNDQRFATTPKILETPKGDN 267
>gi|154492725|ref|ZP_02032351.1| hypothetical protein PARMER_02362 [Parabacteroides merdae ATCC 43184] >gi|154087030|gb|EDN86075.1| hypothetical protein PARMER_02362 [Parabacteroides merdae ATCC 43184] (278 aa)
Score = 334, Expect = 2.1e-29, Identities = 75/214 (35%), Positives = 122/214 (57%)
  Q:    93 ENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           E I+ H  YLINLG P+        +  + E+ R  Q+    +  HPGS L+  +    +  IA+++N A++ T   V   +E  AG+G+ +G  FE+++ I+  V++K R+GVC+DT H   +G DI   +   +T   F + +  SY++ +H+NDSK ++ +R DRHD+IG G +G         + +  N+P ILETP   D+ I+ +EI  L S
  S:    64 EYILPHDSYLINLGHPEAEGLQKSRDAFLDEMQRCEQLGLNRLNFHPGSHLNQMEVEDCLTRIANSVNWALDQTSG-VCAVLENTAGQGTNLGYTFEQLAYIIDKVEDKSRVGVCIDTAHTLAAGYDIKTVEGFTETFRHFDEVIGFSYLRGMHINDSKKDLATRVDRHDSIGKGVMGLTTFKMLMDDPRFDNIPLILETP---DESIWSEEIEYLYS 277
>gi|45185176|ref|NP_982893.1| ABL054Cp [Ashbya gossypii ATCC 10895] >gi|44980812|gb|AAS50717.1| ABL054Cp [Ashbya gossypii ATCC 10895] (359 aa)
Score = 333, Expect = 2.4e-29, Identities = 86/282 (30%), Positives = 137/282 (48%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEWKE 311
            G+HV       +  SV+       N F +F   P+ ++ K      I       +E       +++ H  Y INL +P            + ++ R  Q+   L   HPGSAL  + +  +  +A  +N+AI  T   V I +E MAG G+ +G   E++  ++  V+ K R+GVC+DTCH   +G DI      D   ++F   L + Y+  +H+NDSK  + +  DRH+ +G G +G +     A ++ L N+P ILETP ++D   Y +EI  L   EW E
  S:    13 FGAHV--SGAGGISNSVVNAHRIGCNAFAMFLKSPKQWVSKAYSAEEIKRFHDNCEELGYNPRTDVLPHGLYFINLANPDREKAEKAYGAFLDDLQRCEQLGIGLYNFHPGSALKGEYDAQLRQLAMYINRAISET-KFVKIVLENMAGHGNIIGSKLEDLRTVIDLVEQKDRVGVCVDTCHTFAAGYDIRSRAAFDSFWDKFRTTLGMQYLASMHINDSKAPLAANADRHELLGQGFLGLEAFRLIARSDFLQNIPIILETPQKEDDG-YGEEIKML---EWLE 290
>gi|11066945|gb|AAG28773.1|AF300991_1 endonuclease IV [Salmonella typhimurium] (226 aa)
Score = 331, Expect = 4.0e-29, Identities = 74/211 (35%), Positives = 116/211 (54%)
  Q:    51 EYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIG 261
           E     F +FT   + +    L   +ID+  K+  EK       I+ H  YLINLG P         +  + E+ R  Q+   L+  HPGS L    +   +  IA+++N A+  T+  V   +E  AG+GS +G  FE+++ I+ GV++K R+GVC+DTCH   +G D+  P   ++T  EF K +   Y++ +HLND+K+  GSR DRH ++G
  S:    14 EIGATAFALFTKNQRQWRAAPLTPQVIDD-FKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEG-VTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLG 226
>gi|153003967|ref|YP_001378292.1| apurinic endonuclease Apn1 [Anaeromyxobacter sp. Fw109-5] >gi|152027540|gb|ABS25308.1| apurinic endonuclease Apn1 [Anaeromyxobacter sp. Fw109-5] (280 aa)
Score = 331, Expect = 4.5e-29, Identities = 86/267 (32%), Positives = 139/267 (52%)
  Q:    25 KNKLLLGSHVGFKAKNYLVGSVLETLEYDG-NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGV--KNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETPYR 291
           + ++LLG+H G       V +     E DG +C  +FT   + +  K L+    +E  +   E     L     H+ YLIN  S     R      L  E+ R   +    ++ HPGS  D    + +  +A+ + +A++A      + VET AG+GS +G  FE V+ I   V    ++R+GVC+DTCH+  +G DI+      +T+EE  + + L+ ++  HLNDSK  +G R DRH++IG G +G   F +LV   ++ + A +P  +ET  R
  S:     2 RARMLLGAHEGIAGG---VSTAFTRAEADGADCLQIFTRNARGWAAKPLEA---EEIARFKGEAKRTKLPT-AAHSSYLINCCSEDADIRRKSWAGLADELGRCEALGIPSLIFHPGSHCDEAEGIRL--VAEAMERALDAVPGKARLLVETTAGQGSSLGWRFEHVAAIRDAVPAAKRRRVGVCVDTCHVFAAGYDITHEAGYHRTIEELDRVVGLANVRAFHLNDSKKPLGCRVDRHEHIGEGAMGITPFRFLV---NDARFAELPGFVETESR 265
>gi|154150197|ref|YP_001403815.1| apurinic endonuclease Apn1 [Candidatus Methanoregula boonei 6A8] >gi|153998749|gb|ABS55172.1| apurinic endonuclease Apn1 [Candidatus Methanoregula boonei 6A8] (281 aa)
Score = 329, Expect = 7.3e-29, Identities = 78/242 (32%), Positives = 130/242 (53%)
  Q:    53 DGNC--FMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY---RDDK 294
           D  C  F +F+  P+ +  K L +   D   K +     L ++    H PYL NL SPK       +  L  E++R N++    +V H G  L          +   +N  + ++++  ++ +E  AG+ + VG +FE +  I++G+ ++KRIGVC DTCH   +G ++   +    TL +F + + +S ++VIHLND+K ++GS  DRH++IG G +  D      HN   A +P + ETP    RDD+
  S:    25 DAGCDVFQMFSRNPRGWGYKPLSEGDCDLYKKKIAATGLLPVD----HMPYLPNLASPKTEIWEKSVQTLNAELDRCNRLGIPYLVTHLGHHLGDGIAGGRARVIKAINTVLASSESGTMLLLENTAGEKNSVGSSFEHIGAILAGLSDEKRIGVCFDTCHAFAAGYELRTREGITSTLAQFDEQVGISRLRVIHLNDTKGDLGSGLDRHEHIGMGFISEDGFRHILHNPVFARLPLVCETPVDERRDDR 270
>gi|7490448|pir||T41497 DNA (apurinic or apyrimidinic site) lyase, endon uclease - fission yeast (Schizosaccharomyces pombe) (349 aa)
Score = 329, Expect = 8.3e-29, Identities = 78/273 (28%), Positives = 144/273 (52%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           ++G+H+   A   +  +++     + N    F    + +   +L +++  + ++   E      + ++VH  YLIN+ +  E  R    N  + ++ R  ++   L   HPGS     +   IN++A+ +N+A E T + VII  E MAG+G+ +G  F++ + + S +KN  R  VCLDTCH   +G DI   +   + ++EF + +   Y+   HLNDSK  +GS +D H+NIG G +G +      ++ +   +P +LETP +  +  +K+E+
  S:     1 MIGAHI--SAAGGVFNALINMKNINANSCAFFVKSQRKWTSPDLSEDVAQKFLETASEMKFDASKQVLVHGSYLINMANADEQKREQAFNCFVDDLKRCERLGVGLYNFHPGSTASCTKEEGINNLAECINRAHEETKS-VIIVTENMAGQGNCLGGTFDDFAALKSKIKNLDRWRVCLDTCHTFAAGYDIRTEESYKKVIDEFDEKVGAKYVSGWHLNDSKAPLGSNRDLHENIGLGFLGLEPFRLIMNDSRWDGIPLVLETPAKSPEQ-WKKEV 272
>gi|193084141|gb|ACF09807.1| endonuclease IV [uncultured bacterium SAT53-B3] (243 aa)
Score = 328, Expect = 9.4e-29, Identities = 84/232 (36%), Positives = 133/232 (57%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKEL-DQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL---------DSDRNVAINHIADNLNKAIEATDN-DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIG 261
           LG+HV       L  ++   LE + + F +F+   + ++ K L D+N+  EA K    K  L    +++H  YLIN+GSP E+         + E +R   +    +  HPGS              R+ A+  IAD++NK ++ T   D  + +E  AG+G+ VGI FEE+  I+  + +KKR+GVC+DT H   SG D  +D +Q  ++F   + + Y+  +HLNDSK+++G+R DRHDNIG
  S:     3 LGAHVSVAGG--LQNAIPWALEIEADTFQMFSKNQRQWIAKPLTDENI--EAFKTPLAKTDL--GPLMIHDSYLINMGSPDETKGKRAQVAFLEEYHRCEALGVAYLNFHPGSHTHPKKDMRDDKQTRDEALERIADHMNKTLKETKGYDSKLVIENAAGQGTNVGIKFEEIKHIIDHIDDKKRVGVCIDTQHAWASGYDWRNDFNQIWDDFESIVGMEYLVALHLNDSKSDLGTRVDRHDNIG 240
>gi|145299169|ref|YP_001142010.1| endonuclease IV [Aeromonas salmonicida subsp. salmonicida A449] >gi|166224270|sp|A4SMZ0|END4_AERS4 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|142851941|gb|ABO90262.1| endonuclease IV [Aeromonas salmonicida subsp. salmonicida A449] (281 aa)
Score = 328, Expect = 1.0e-28, Identities = 84/277 (30%), Positives = 141/277 (50%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVA-INHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           +G+HV   A   +  ++        N F +FT   + +    L +  I  A KL  EK     E I+ H  YLINLG P     +   +  + EI R  Q+    +  HPGS L      A +  +++++N A+E +   V   +E  AG+G+ +G +FE ++ ++ GV++K R+G+C DTCH   +G D+  P+   Q   +F + +   Y+K +H+N +K   GSR DRH ++  G +G        ++++   +P +LET    D+ I+  EI  L S
  S:     4 IGAHV--SAAGGVENTIARAQAIGANAFALFTKNQRQWQAAPLSEASI-RAFKLACEKAGFRPEQILPHDSYLINLGHPDPDGLAKSRDAFLDEIKRCEQLGLCYLNFHPGSHLKQIPEAASLTLVSESINWALERSQG-VTAVIENTAGQGTNLGWSFEHLATLIDGVEDKSRVGICFDTCHAFAAGYDLRTPESCAQVFADFDRIVGFQYLKGMHINGAKCTFGSRVDRHHSLREGNLGEAVFHHIMNDDRFDGIPLVLETI---DETIWGDEISWLRS 277
>gi|116748106|ref|YP_844793.1| apurinic endonuclease Apn1 [Syntrophobacter fumaroxidans MPOB] >gi|116697170|gb|ABK16358.1| Endonuclease IV [Syntrophobacter fumaroxidans MPOB] (326 aa)
Score = 327, Expect = 1.4e-28, Identities = 81/265 (30%), Positives = 133/265 (50%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKE-KNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIE-ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           LLG+H+       L  +    L+  G    VF    + +    L  +    AV+L +E ++      +  H  YLINL +P        +     E++   Q+  + ++LHPG    +  +  I   A NL++A   A  + V + +ET AG+GS +G  FEE++ ++   K  + +GVC DTCH   +G D+ D    ++T + F K + L  ++  HLNDSK   GSR DRH++IG G++G        ++ +  + P +LETP   D
  S:     3 LLGAHMSIAGG--LHNAFQRLLQVRGEALQVFLKNQRQWHPPPLSAH----AVRLFQEERDNFAHVPVAAHDSYLINLAAPDPDIAEKSVGAFASELDACAQLGIEFLILHPGFHRGAGISTGIARFAKNLDRACALAKAHSVTVLIETTAGQGSGIGSKFEEIADMLMKSKAGRPLGVCFDTCHAFAAGYDLRDERSYERTFDRFEKTIGLRLLRWFHLNDSKAGFGSRVDRHEHIGRGRIGLQGFRLLVNDPRFESHPMVLETPKGKD 266
>gi|27904631|ref|NP_777757.1| endonuclease IV [Buchnera aphidicola str. Bp (Baizongia pistaciae)] >gi|29611724|sp|P59496|END4_BUCBP Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|27904028|gb|AAO26862.1| putative endonuclease IV [Buchnera aphidicola str. Bp (Baizongia pistaciae)] (278 aa)
Score = 326, Expect = 1.7e-28, Identities = 93/277 (33%), Positives = 144/277 (51%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINH----IADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           +G+HV   A   L   +  + E     F  F   P  +   +     I + + L K+ N  + + I+ H+ YLINLG P +          + EI    +++  L+  HPGS L   R ++  H    +AD++N A++ T   V + +E  AG+GS +G  FE +++I+  VK K RIG+CLDTCH+H SG D+       QT + F+  + L Y+  +H+NDSK +  SR DRH N+G G +G   +     N      P ILET    +  ++K EI  +NS
  S:     4 IGAHV--SAAGGLDQVIFRSKELGATAFSFFLSNPLRWNLIQFRDETIKKFIFLCKKFN-YVSDQILPHSSYLINLGHPSDEHLKKSRLLFVNEIINCKKLNLSLLNFHPGSHL---RKISEQHCLIRVADSINFALQNTVG-VKLVIENTAGQGSNIGYCFEHLAQIIHKVKEKDRIGICLDTCHLHASGYDLKTELGCRQTFKAFNDIVGLHYLSGMHINDSKTKRNSRIDRHHNLGQGYIGKSSIRWIIRNINFKLFPMILET---TNNKLWKDEINWINS 277
>gi|170288369|ref|YP_001738607.1| apurinic endonuclease Apn1 [Thermotoga sp. RQ2] >gi|170175872|gb|ACB08924.1| apurinic endonuclease Apn1 [Thermotoga sp. RQ2] (287 aa)
Score = 326, Expect = 1.7e-28, Identities = 83/242 (34%), Positives = 127/242 (52%)
  Q:    48 ETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQT---LEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           +T+   GN F +F    +++  K L  + +    K   +KN +  EN   H+ YLINL SPKE      +  L  E+    ++  + + +HPGS L +     I+ I   LN+ +  T+  V+I +E ++ KG  +G   E++ KI   V  K R+ V  DTCH  DSG DI+  +     L E      L  +K+IHLNDSK  +G+ KDRH+ IG G +G +    +   +++  VP ILETP
  S:    20 DTVNIGGNSFQIFPHNARSWGAK-LPSDEVATKFKREMKKNGIDWENAFCHSGYLINLASPKEDIWQKSVELLKKEVEICRKLGIRYLNIHPGSHLGTGEEEGIDRIVRGLNEVLNNTEG-VVILLENVSQKGGNIGYKLEQLKKIRDLVDQKDRVAVTYDTCHGFDSGYDITKKEGVEALLNEIETLFGLERLKMIHLNDSKYPLGAAKDRHERIGSGFIGEEGFAVFFSFKEIQEVPWILETP 262
>gi|91204144|emb|CAJ71797.1| similar to endonuclease IV [Candidatus Kuenenia stuttgartiensis] (278 aa)
Score = 326, Expect = 1.9e-28, Identities = 83/262 (31%), Positives = 142/262 (54%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKEL---DQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND-VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           +LLG H   K    L  +  E      + F +FT   + +  K +   ++ +  E    +++ N   ++ I  HA YLINL +      +L  N L+ EI R + +    I++HPG   ++ +   + ++   +   ++ T+N  V I +E  AG+GS +G +F+++ +++ G+    RIGVC DTCH   +G DI      + T+EE    + L+ +  IHLNDSK  +GS+ DRH++IG G +G +   +  +  K  ++PKILETP
  S:     1 MLLGVHCSIKGS--LHNAFNEAASLGIDTFQIFTKNQRQWKEKIVGPAEKTIFRET---LRQSN---IKTIFSHASYLINLATSDSRIYALTHNSLLGEIQRCDDLGIASIIIHPGFTKNTGKQTGMKNVIKMIKSVLKKTNNSPVKILMENTAGQGSSIGYHFKQLQQLIEGI-GSGRIGVCFDTCHAFAAGYDIRTKIGFETTMEELDATVGLNSLYAIHLNDSKGALGSKIDRHEHIGQGAIGLEPFRQIMNTMK--HIPKILETP 258
>gi|55378731|ref|YP_136581.1| endonuclease IV [Haloarcula marismortui ATCC 43049] >gi|59797655|sp|Q5V0S8|END4_HALMA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|55231456|gb|AAV46875.1| probable endonuclease IV [Haloarcula marismortui ATCC 43049] (277 aa)
Score = 325, Expect = 2.5e-28, Identities = 81/265 (30%), Positives = 141/265 (53%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATD--NDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK 294
           +G+H       Y   +V E +EY GNC  +F+  PQ +    +D    DEA +         +   V+H+ YL+NL +PK+  R   L+ +  E++   ++  + + +H G+         ++   DN    ++  D    V + VE+ AG G+++G  FE ++ +    +  + I  CLDT HM  +G D+S P   D+TL EF + + +  +  +HLNDSK+E G+ KD H +IG G +G D +  + +++ + +VP +LETP  + K
  S:     4 VGAHTSIAGGVY--NAVEEQVEYSGNCGQIFSHSPQVWQDPNIDD---DEAEQFRDLAADHGVGPWVIHSSYLVNLCTPKDDLREKSLDSMQKEVDAAAKLGIEYVNVHLGA----HTGAGVDGGLDNAASVLDDLDIPEGVTVLVESDAGSGTKLGGQFEHLATVRE--RTDQDIEFCLDTAHMFAAGYDLSTPEAVDETLAEFDEVVGVEDLACVHLNDSKHECGTNKDEHAHIGEGHIGEDGMRAFVNHDAIRDVPLVLETPTENGK 262
>gi|163781824|ref|ZP_02176824.1| deoxyribonuclease IV [Hydrogenivirga sp. 128-5-R1-1] >gi|159883044|gb|EDP76548.1| deoxyribonuclease IV [Hydrogenivirga sp. 128-5-R1-1] (279 aa)
Score = 324, Expect = 2.6e-28, Identities = 89/276 (32%), Positives = 138/276 (50%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLE----YDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI-EATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           L G+HV         GS+L T E         F  F   P+ +  K +   L    V+  KE+       ++VH+PYL+NL S  E  R   ++  + E+   + +       HPG+A       AI +I  +L +   E   +   + +E  AG+  ++G +F E+++IV G  N  RIGVCLDTCH    G +I+ P   D+ L E  K L    IK +H NDSK  +G+R+DRH++IG G +G +       +E   ++P  +ETP   D      +++NL
  S:     3 LFGAHVSS------AGSILNTFERAKDIGAEVFQFFLRSPRVWRWKGISNKL----VRKFKEELEGFGNPVMVHSPYLLNLASSNEELRRKSVSVFLEELKFCDSVGIHFYNFHPGTAKGISEEEAIKNILVSLEEVFREYEPSRTTVLLENTAGERGDMGKSFRELAEIV-GAFNGVRIGVCLDTCHAFAYGYEINTPKGFDEFLREVEKTLGFDRIKAVHANDSKVPLGARRDRHEHIGEGYIGIEGFRNLLSHEYFGSLPYYIETPKEGD-----MDVVNL 270
>gi|63054441|ref|NP_588189.2| AP endonuclease Apn1 [Schizosaccharomyces pombe] >gi|48429230|sp|P50525|APN1_SCHPO DNA-(apurinic or apyrimidinic site) lyase 1 (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) >gi|7490449|pir||T41498 DNA (apurinic or apyrimidinic site) lyase, endon uclease - fission yeast (Schizosaccharomyces pombe) >gi|40287244|gb|AAR83751.1| AP-endonuclease-like protein [Schizosaccharomyces pombe] >gi|47023035|emb|CAB61503.4| AP endonuclease Apn1 [Schizosaccharomyces pombe] (342 aa)
Score = 324, Expect = 3.0e-28, Identities = 71/209 (33%), Positives = 119/209 (56%)
  Q:    93 ENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           + ++VH  YLIN+ +  E  R    N  + ++ R  ++   L   HPGS     +   IN++A+ +N+A E T + VII  E MAG+G+ +G  F++ + + S +KN  R  VCLDTCH   +G DI   +   + ++EF + +   Y+   HLNDSK  +GS +D H+NIG G +G +      ++ +   +P +LETP +  +  +K+E+
  S:    56 KQVLVHGSYLINMANADEQKREQAFNCFVDDLKRCERLGVGLYNFHPGSTASCTKEEGINNLAECINRAHEETKS-VIIVTENMAGQGNCLGGTFDDFAALKSKIKNLDRWRVCLDTCHTFAAGYDIRTEESYKKVIDEFDEKVGAKYVSGWHLNDSKAPLGSNRDLHENIGLGFLGLEPFRLIMNDSRWDGIPLVLETPAKSPEQ-WKKEV 265
>gi|117619212|ref|YP_856627.1| endonuclease IV [Aeromonas hydrophila subsp. hydrophila ATCC 7966] >gi|166224269|sp|A0KK26|END4_AERHH Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|117560619|gb|ABK37567.1| endonuclease IV [Aeromonas hydrophila subsp. hydrophila ATCC 7966] (281 aa)
Score = 322, Expect = 5.1e-28, Identities = 85/278 (30%), Positives = 139/278 (50%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVA-INHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
            +G+HV   A   +  ++        N F +FT   + +    L +  I  A KL  EK     E I+ H  YLINLG P     +   +  + E+ R  Q+    +  HPGS L      A +  +++++N A+E +   V   +E  AG+G+ +G +FE ++ I+ GV++K R+G+C DTCH   +G D+   D       EF + +   Y+K +H+N +K   GSR DRH ++  G +G        ++++   +P ILET    D+ I+  EI  L S
  S:     3 FIGAHV--SAAGGVENTIARAQAIGANAFALFTKNQRQWQAAPLSEASI-HAFKLACEKGGFRPEQILPHDSYLINLGHPDPDGLAKSRDAFLDEMKRCEQLGLCYLNFHPGSHLKQIPEAASLKLVSESINWALERSQG-VTAVIENTAGQGTNLGWSFEHLATIIDGVEDKSRVGICFDTCHAFAAGYDLRTADACAAVFAEFEQTVGFQYLKGMHINGAKCTFGSRVDRHHSLREGNLGEAVFHHIMNDDRFDGIPLILETI---DESIWGDEIRWLRS 277
>gi|58270324|ref|XP_572318.1| DNA-(apurinic or apyrimidinic site) lyase [Cryptococcus neoformans var. neoformans JEC21] >gi|57228576|gb|AAW45011.1| DNA-(apurinic or apyrimidinic site) lyase, putative [Cryptococcus neoformans var. neoformans JEC21] (463 aa)
Score = 321, Expect = 6.7e-28, Identities = 85/265 (32%), Positives = 139/265 (52%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLL----ENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSE-VGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRD 292
           +LLG+HV   A      ++L       N   +F    + +  K  +   +    +LMK K    +    E+I+VH  YLINLG+P  +   +       +I R +Q+  KL   HPGS + +  +  +   IA  +N+ +     +VI  +E MA  GS  VG  + ++S I+  V++K R+ VC+DTCH   +G DI  P+   +T++ F + +   Y+  +HLNDSK  +G+ KD H+NIG G++G         +  +  +P +LETP  D
  S:   115 MLLGAHV--SAAGGPATALLRAGLAGANGLALFVKSQRQWKSKPYEDETVQRFKELMKSKEEGGMGYGPESILVHGSYLINLGNPDPAKWKVSYECFKDDIARCHQLGIKLYNWHPGSTVGACTKEESFALIAKAINQ-VHKDVPEVITVIENMANAGSNIVGTAWSDLSSIIKLVEDKSRVRVCIDTCHTFAAGYDIRTPETYAETMKRFDEVVGNKYLAGVHLNDSKANLGANKDLHENIGLGEIGLTAFRCIMRDPLMTGIPLVLETPAPD 385
>gi|149908884|ref|ZP_01897544.1| endonuclease IV [Moritella sp. PE36] >gi|149808158|gb|EDM68099.1| endonuclease IV [Moritella sp. PE36] (282 aa)
Score = 320, Expect = 7.5e-28, Identities = 70/207 (33%), Positives = 120/207 (57%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI---SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           I+ H  YLINLG P+ +      N    E++R  Q+   L+  HPGS L     + ++  +A+++N A+E +   V   +E  AG+G+ +G  FE +++I+  V++K R+GVC+DTCH   +G D+   +  ++T  +FS  +   Y+  +H+NDSK ++G++ DRH ++G G +G D       +E+   +P +LET    D  I+  EI
  S:    67 ILPHDSYLINLGHPEMAALEKSRNAFYDEMHRCEQLGLTLLNFHPGSHLKKISESESLKLVAESINLALEKS-TSVKAVIENTAGQGTNLGYRFEHLAEIIEQVEDKSRVGVCIDTCHTFVAGYDLRTFTACEKTFNDFSSIVGFEYLAGMHINDSKVDLGTKVDRHHSLGQGFIGDDAFKFIMQDERFNGIPMVLETI---DDTIWADEI 273
>gi|134117748|ref|XP_772508.1| hypothetical protein CNBL1230 [Cryptococcus neoformans var. neoformans B-3501A] >gi|50255122|gb|EAL17861.1| hypothetical protein CNBL1230 [Cryptococcus neoformans var. neoformans B-3501A] (463 aa)
Score = 320, Expect = 7.9e-28, Identities = 85/265 (32%), Positives = 139/265 (52%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLL----ENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSE-VGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRD 292
           +LLG+HV   A      ++L       N   +F    + +  K  +   +    +LMK K    +    E+I+VH  YLINLG+P  +   +       +I R +Q+  KL   HPGS + +  +  +   IA  +N+ +     +VI  +E MA  GS  VG  + ++S I+  V++K R+ VC+DTCH   +G DI  P+   +T++ F + +   Y+  +HLNDSK  +G+ KD H+NIG G++G         +  +  +P +LETP  D
  S:   115 MLLGAHV--SAAGGPATALLRAGLAGANGLALFVKSQRQWKSKPYEDETVQRFKELMKSKEEGGMGYGPESILVHGSYLINLGNPDPAKWKVSYECFKDDIARCHQLGIKLYNWHPGSTVGACTKEESFALIAKAINQ-VHKDVPEVITVIENMANAGSNIVGTAWSDLSSIIKLVEDKSRVRVCIDTCHTFAAGYDIRTPETYAETMKRFDEVVGNKYLGGVHLNDSKANLGANKDLHENIGLGEIGLTAFRCIMRDPLMTGIPLVLETPAPD 385
>gi|126178588|ref|YP_001046553.1| apurinic endonuclease Apn1 [Methanoculleus marisnigri JR1] >gi|166224285|sp|A3CT71|END4_METMJ Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|125861382|gb|ABN56571.1| Endonuclease IV [Methanoculleus marisnigri JR1] (282 aa)
Score = 319, Expect = 9.9e-28, Identities = 83/262 (31%), Positives = 132/262 (50%)
  Q:    28 LLLGSHVGFKAK-NYLVGSVLETLEYDGNC--FMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIE-ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           +L+G HV      +  VG  L     D  C  F +F+  P+ +  K+LD  L   A       +   +  +V H PYL N  SP        +  L  E+ R + +    +V H G    +        +   +N+A E A ++DV++ +E  AG+ + VG   + +S+IV G+  K+R+G+C DTCH   +G D+      D  L E    +DLS ++V+HLND K ++GS  DRH++IG G++G D       +  +  +P I ETP
  S:     2 VLVGCHVSIAGSIDRAVGRAL-----DAGCDTFQIFSRNPRGWKVKDLDPGL---AGAFRAAVSASGIGPVVDHMPYLPNPASPDAEIYEKSVAALAGELRRCSLLGIPYLVTHLGHHRGAGMEAGQERVVAAINRAFEDAGESDVMLLLENTAGEKNSVGTTVDNLSRIVDGIDAKERVGICFDTCHAFAAGYDLRTAEGVDAVLGEIDDAIDLSRLRVVHLNDCKGDLGSGLDRHEHIGLGRIGEDGFRHILRHPAVRRLPLICETP 262
>gi|167753951|ref|ZP_02426078.1| hypothetical protein ALIPUT_02236 [Alistipes putredinis DSM 17216] >gi|167658576|gb|EDS02706.1| hypothetical protein ALIPUT_02236 [Alistipes putredinis DSM 17216] (281 aa)
Score = 319, Expect = 1.1e-27, Identities = 71/211 (33%), Positives = 116/211 (54%)
  Q:    94 NIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           +I+ H  YLINLG P+           I E++R   +    +  HPGS L+       ++ IA+++N A++ T   V   +E  AG+GS +G  FE ++ I+  V++K R+G+C+DTCH   +G D+      D T  E  + + L Y++ +HLND+   +GS  DRH  +G G +G +     A + +  ++P ILETP   D+  + +EI  L
  S:    65 SILPHDSYLINLGHPEREGLEKSRTAFIDEMSRCQALGLDRLNFHPGSHLNRISTEECLDRIAESINIALDRTQG-VTAVIENTAGQGSNLGFRFEHLAYIIDKVEDKSRVGICIDTCHAFTAGYDLRTAAACDATFSELDRIVGLKYLRGMHLNDTLKTLGSHVDRHAPLGEGVLGIECFRYIARDSRFDDMPLILETP---DESRWAEEIAEL 275
>gi|118577095|ref|YP_876838.1| endonuclease IV [Cenarchaeum symbiosum A] >gi|118195616|gb|ABK78534.1| endonuclease IV [Cenarchaeum symbiosum A] (280 aa)
Score = 317, Expect = 1.9e-27, Identities = 80/249 (32%), Positives = 126/249 (50%)
  Q:    45 SVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISD---PDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY---RDD 293
           SV   +E     F +F+  P+ +  KE+ ++      K +KE   +      VH PYL NL S  + +    ++ LI E+ R   +    +V H GS L +     I  +     K+     N V I +E  AG+ + VG  F ++  I+S ++  KR GVCLDTCH    G D+S      ++ +EF K + L  ++V+HLND+K   GS+ DRH ++G G +G + +   A       +P ++ETP    RDD
  S:    16 SVDNAVERGCTAFQIFSRNPRGWRAKEISKDEAGTFKKKLKESK-IEPSGTCVHMPYLPNLASTNDESHKKSVDTLIGEVERCGLLGIPFLVTHLGSHLGAGEEKGIERLVKAY-KSAAGVKNGVTILLENTAGQKNSVGSEFGQLGSILSQLRPAKRFGVCLDTCHAFAYGYDLSTRAGAKKSFDEFDKKVGLDNLRVLHLNDAKAGCGSKLDRHYHVGLGSIGKEGMRAAARLASKRGIPMVVETPVDETRDD 268
>gi|148269693|ref|YP_001244153.1| apurinic endonuclease Apn1 [Thermotoga petrophila RKU-1] >gi|166224294|sp|A5IK54|END4_THEP1 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|147735237|gb|ABQ46577.1| Endonuclease IV [Thermotoga petrophila RKU-1] (287 aa)
Score = 315, Expect = 3.2e-27, Identities = 79/242 (32%), Positives = 127/242 (52%)
  Q:    48 ETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQT---LEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           +T+   GN + +F    +++  K    ++  +  + MK K  +  EN   H+ YLINL SPKE      +  L  E+    ++  + + +HPGS L +        I   LN+ + +T+ DV+I +E ++ KG  +G   +++ KI   V  K R+ +  DTCH  DSG DI+  +     L E      L  +K+IHLNDSK  +G+ KDRH+ IG G +G +    +   +++  VP ILETP
  S:    20 DTVNIGGNAYQIFPHNARSWSAKLPSDDITTKFKREMK-KYGIDWENAFCHSGYLINLASPKEDIWQKSVELLKKEVEICRKLGIRYLNIHPGSHLGAGEKEGTERIVRGLNEVLNSTE-DVVILLENVSQKGGNIGYKLDQLKKIRDLVDQKDRVAITYDTCHGFDSGYDITKKEGVEALLNEIETLFGLERLKMIHLNDSKYPLGAAKDRHERIGSGFIGEEGFAVFFSFKEIQKVPWILETP 262
>gi|110601589|ref|ZP_01389769.1| apurinic endonuclease (APN1) [Geobacter sp. FRC-32] >gi|110547710|gb|EAT60956.1| apurinic endonuclease (APN1) [Geobacter sp. FRC-32] (285 aa)
Score = 314, Expect = 4.3e-27, Identities = 77/216 (35%), Positives = 110/216 (50%)
  Q:    78 DEAVKLMKEK-NPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI-EATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           D  + L KEK     L  ++ H  YLINL S     R   LN    E+ R +++    IV+HPGS       V +  I +  +  I E       I +ET AG+G+ +G  FE +  I+ G  +  R GVC DTCH   +G DI+      Q  EEF + + L  ++  H NDSK  +  R DRH++IG G +G        ++ + A +PKILETP  D+
  S:    47 DPDILLFKEKLAESGLNEVISHDIYLINLASAPGEIRDKSLNGFQEEMIRCSRLGIGKIVMHPGSHNGDGEEVGLRRIIEAFDYLIAETPAYSGKILLETTAGQGTNLGYTFEHLRTIIEGSAHPDRFGVCYDTCHTFAAGYDITSAAAYGQVWEEFDRIIGLDRLQCFHFNDSKKGLNCRIDRHEHIGKGAIGATAFSLIMNDPRFAGIPKILETPKGDN 267
>gi|15643130|ref|NP_228173.1| deoxyribonuclease IV [Thermotoga maritima MSB8] >gi|8928109|sp|Q9WYJ7|END4_THEMA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|4980865|gb|AAD35449.1|AE001716_12 deoxyribonuclease IV [Thermotoga maritima MSB8] (287 aa)
Score = 313, Expect = 5.0e-27, Identities = 81/242 (33%), Positives = 125/242 (51%)
  Q:    48 ETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKE--KNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQT---LEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           +T+   GN F +F   P N           + A K  +E  K+ +  EN   H+ YLINL SPK+      +  L  E+    ++  + + +HPGS L +     I+ I   LN+ +  T+  V+I +E ++ KG  +G   E++ KI   V  + R+ +  DTCH  DSG DI+  +     L E      L  +K+IHLNDSK  +G+ KDRH+ IG G +G +    +   +++  VP ILETP
  S:    20 DTVNIGGNSFQIF---PHNARSWSAKLPSDEAATKFKREMKKHGIDWENAFCHSGYLINLASPKDDIWQKSVELLKKEVEICRKLGIRYLNIHPGSHLGTGEEEGIDRIVRGLNEVLNNTEG-VVILLENVSQKGGNIGYKLEQLKKIRDLVDQRDRVAITYDTCHGFDSGYDITKKEGVEALLNEIESLFGLERLKMIHLNDSKYPLGAAKDRHERIGSGFIGEEGFAVFFSFKEIQEVPWILETP 262
>gi|159124264|gb|EDP49382.1| DNA (apurinic or apyrimidinic site) lyase, endon uclease [Aspergillus fumigatus A1163] (561 aa)
Score = 313, Expect = 5.1e-27, Identities = 77/242 (31%), Positives = 125/242 (51%)
  Q:    54 GNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGV--KNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKP 295
           GN F +F    + +    L  +  D+  +L  E      ++I+ H  YL+NL    +       +  + ++ R   +   L   HPGSA  S    A++ +A  L  A+EAT   V+  +ETM G G+ +G    E   +++ +  ++  RIG+C+DTCH   +G D+S P      ++EF   + L Y++ +HLNDSK   GS++D H NIG G +G        ++ +L  +P ILETP   D+P
  S:   160 GNAFALFLKSQRKWENPPLQDDHRDQFRQLCLEHKYDGAKHILPHGSYLVNLAQEDKVKAKQAYDSFLDDLRRCEALGITLYNFHPGSANQSSLPDALSRLAKALTNALEATST-VVPVLETMCGHGTTIGGYLSEFRDLLALIPREHHPRIGICIDTCHSFAAGYDLSSPAGYQSFMKEFEDQIGLQYLRALHLNDSKAPRGSKRDLHANIGTGFLGLRAFHNIMNDPRLEGLPMILETPI--DRP 403
>gi|70991705|ref|XP_750701.1| DNA (apurinic or apyrimidinic site) lyase, endon uclease [Aspergillus fumigatus Af293] >gi|66848334|gb|EAL88663.1| DNA (apurinic or apyrimidinic site) lyase, endon uclease [Aspergillus fumigatus Af293] (561 aa)
Score = 313, Expect = 5.1e-27, Identities = 77/242 (31%), Positives = 125/242 (51%)
  Q:    54 GNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGV--KNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKP 295
           GN F +F    + +    L  +  D+  +L  E      ++I+ H  YL+NL    +       +  + ++ R   +   L   HPGSA  S    A++ +A  L  A+EAT   V+  +ETM G G+ +G    E   +++ +  ++  RIG+C+DTCH   +G D+S P      ++EF   + L Y++ +HLNDSK   GS++D H NIG G +G        ++ +L  +P ILETP   D+P
  S:   160 GNAFALFLKSQRKWENPPLQDDHRDQFRQLCLEHKYDGAKHILPHGSYLVNLAQEDKVKAKQAYDSFLDDLRRCEALGITLYNFHPGSANQSSLPDALSRLAKALTNALEATST-VVPVLETMCGHGTTIGGYLSEFRDLLALIPREHHPRIGICIDTCHSFAAGYDLSSPAGYQSFMKEFEDQIGLQYLRALHLNDSKAPRGSKRDLHANIGTGFLGLRAFHNIMNDPRLEGLPMILETPI--DRP 403
>gi|189219253|ref|YP_001939894.1| Endonuclease IV [Methylokorus infernorum V4] >gi|189186111|gb|ACD83296.1| Endonuclease IV [Methylacidiphilum infernorum V4] (321 aa)
Score = 312, Expect = 7.8e-27, Identities = 77/219 (35%), Positives = 124/219 (56%)
  Q:    71 ELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGS-AL-DSDRNVAINHIADNLNKAIEATDNDVI-ICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           ++D+  I   V L +E N         H  YLINL S  +      LN L+ EI    ++    +VLHPG+ AL  ++ + AI  +   LN+A+E T N  + I +ETMAG+G ++G   E++ +I+  V + +R   CLDT H+ ++G ++       +T+E+ +  L LS I  IHLNDS +  GS+ DRH +IG G +G +   +  ++ +   +P +LETP
  S:    83 KIDEKDIVAFVSLKEENNIFFFG----HFSYLINLCSRSKEITQKSLNALVQEIIMAEKLTLPFVVLHPGTIALGKAEISQAIEVLCGYLNQAVELTKNTAVKIALETMAGQGGQLGWKLEQLREIIERVDSPERFCFCLDTAHLWEAGYELKTAGGYQKTMEKIALELGLSRIAAIHLNDSFSPFGSKVDRHAHIGEGTLGVEPFRRLVNDSRFLGIPMVLETP 303
>gi|77920661|ref|YP_358476.1| endonuclease IV [Pelobacter carbinolicus DSM 2380] >gi|77546744|gb|ABA90306.1| Endonuclease IV [Pelobacter carbinolicus DSM 2380] (282 aa)
Score = 312, Expect = 7.9e-27, Identities = 82/274 (29%), Positives = 126/274 (45%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETL----EYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           +LLG+HV       + G V        E       +FT     +  K L    I       +  N   + +++ H  YLINL +     R   L   + E+ R   +    +V+HPG+ LD+  ++ +  IA+       A    V + +E  AG+GS +G   E ++ I+  V  + R GVC DTCH   +G D+S  +   + +EE         I   HLNDSK E GSR DRH +IG G +  +       + +  +VPKILET   D    + +E+
  S:     1 MLLGAHVS------IAGGVSRAFSRAQEIGATAMQIFTKNANRWQAKPLPDKEIKAFAAARENCN---VASVIAHDSYLINLAAADGEKRHRSLAAFVDEMERCAALGIGGLVMHPGAHLDAGEDIGLQRIAEAFRSIFAAAPPQVTVLLENTAGQGSYLGYRLEHLAAIMERVP-EGRFGVCFDTCHAFAAGYDLSSANGYQKVMEECEHLFGTGRIAAFHLNDSKKEQGSRVDRHAHIGEGCIALEAFAALMQDVRFESVPKILETAPGDHNCFHLKEL 271
>gi|15789493|ref|NP_279317.1| hypothetical protein VNG0183G [Halobacterium sp. NRC-1] >gi|169235209|ref|YP_001688409.1| DNA-(apurinic or apyrimidinic site) lyase [Halobacterium salinarum R1] >gi|24636843|sp|Q9HSK7|END4_HALSA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|10579831|gb|AAG18797.1| endonuclease IV [Halobacterium sp. NRC-1] >gi|167726275|emb|CAP13056.1| DNA-(apurinic or apyrimidinic site) lyase [Halobacterium salinarum R1] (275 aa)
Score = 311, Expect = 8.3e-27, Identities = 77/265 (29%), Positives = 146/265 (55%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNL-IDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATD--NDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK 294
           +G+HV       +  +V   L+  GNC  +FT  PQ +     D N+  DEA    +     L    V+H+ YL+NL +PK+  R+  ++ +  E++  + +    + +H G+         ++   DN   A++  D  +DV + +E+ AG G+++G +FE + ++++  ++ + + VC+DT H   +G D+S     + TL  F   + L +++ +HLNDSK+  G+ KD H +IG G +G   +  + +++ +A+VP +LETP+ D +
  S:     3 VGAHVSIAGG--VDNAVTNELDVGGNCGQIFTHSPQVWQ----DPNIGADEAAAFREGTAADLDGPWVIHSSYLVNLCTPKDDLRAKSIDSMQAEVDAAHTLGIPYVNVHLGA----HTGAGVDDGLDNAASALDELDIPDDVTVLIESDAGSGTKLGGDFEHLHEVLT--RSDQDLDVCIDTAHAFAAGYDLSTEAAVNDTLAAFDDVVGLDHLQYVHLNDSKHACGTNKDEHAHIGEGHIGEAGMRAFINHDAIADVPLVLETPHEDGR 261
>gi|121591801|ref|ZP_01678994.1| endonuclease 4 [Vibrio cholerae 2740-80] >gi|121546336|gb|EAX56607.1| endonuclease 4 [Vibrio cholerae 2740-80] (200 aa)
Score = 311, Expect = 8.7e-27, Identities = 67/182 (36%), Positives = 107/182 (58%)
  Q:   123 EINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           E+ R +Q+   L+  HPGS L        +  IA+++N A     N VI  +E  AG+GS +G  FE ++ I+  V++K+R+GVCLDTCH   +G D+      D+T  EF + + + Y++ +H+NDSK ++ SR DRH ++G G++G++     A + +   +P ILET    D  I+  EI  L
  S:    10 EMLRCDQLGLTLLNFHPGSHLQQVSEEACLATIAESINLAHRQVPN-VIAVIENTAGQGSNLGWRFEHLAAIIDQVEDKERVGVCLDTCHTFAAGYDLRTKAACDETFAEFERVVGMHYLRAMHINDSKGKLASRVDRHHSLGMGEIGWECFEYIAQDARFNGIPLILETI---DPDIWATEIATL 191
>gi|13541802|ref|NP_111490.1| endonuclease IV [Thermoplasma volcanium GSS1] >gi|24636840|sp|Q97A09|END4_THEVO Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|14325218|dbj|BAB60143.1| endonuclease IV [Thermoplasma volcanium GSS1] (280 aa)
Score = 311, Expect = 8.8e-27, Identities = 79/238 (33%), Positives = 126/238 (52%)
  Q:    57 FMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATD-NDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP-DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK 294
           F  F    +N MR        +EA++ + E +   + + +VHA YLINL S          N  + EI R  +I +  +  HPGS  + D  +        + +AIE  + + V + VE  AG+G+ +G    E+ +I+ G  +   +GVC+DTCH   +G DI++  D+ ++E    + L  I   HLND+  ++GS  DRH+ IG GK+G + L+K   + +L   PKI+ETPY + K
  S:    36 FRTFQFFSKNQMRWNSTPISEEEALRFISEVSSHSISSTMVHASYLINLASSSNELHQKSFNAFVEEIQRAERIDATFLTFHPGSNGNKDEGIR------KIKEAIEKVETHKVKLLVENTAGQGNVIGSTIYEIGQIIDGFDSS--VGVCIDTCHAWAAGYDITNKYDEFIDELDSAIGLDRIYAFHLNDAMKDLGSNIDRHELIGRGKIG-EGLIKLISDVRLFGKPKIMETPYGEAK 266
>gi|119193544|ref|XP_001247378.1| hypothetical protein CIMG_01149 [Coccidioides immitis RS] >gi|90306164|gb|EAS35795.1| hypothetical protein CIMG_01149 [Coccidioides immitis RS] (557 aa)
Score = 311, Expect = 9.8e-27, Identities = 77/269 (28%), Positives = 136/269 (50%)
  Q:    27 KLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNK--KRIGVCLDTCHMHDSGIDISDPDQ---TLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKP 295
           ++ +G+HV   A   +  +V  +L   GN F +F    + +    +  +  D+   L  E      + ++ H  YL+NL     +  +   N  I ++ R  ++  KL   HPG++  S    A++ +A  L  A++AT   VI  +ET  G G+ +G        +++ +      R+G+CLDTCH   +G D+   D     ++EF + + L +++ +H+NDSK  +GS +D H NIG G +G        ++++L  +P ILETP   D+P
  S:   120 RMFIGAHV--SASKGIHNAVTNSLHIGGNAFALFLKSQRKWDNPPMQDDHRDQFRTLCSEHKYDASKYVLPHGSYLVNLAQEDPTKANQAYNSFIDDLRRCEELGIKLYNFHPGASNQSTLESALSRLAKALIAALDATKT-VIPVLETTCGHGTSIGGPLSHFKSLLALIPESYHSRLGICLDTCHTFAAGYDLRTQDTWNAFMKEFDETVGLKFLRALHINDSKTPLGSNRDLHANIGTGFLGLRAFHNVMNDKRLEGLPMILETPI--DRP 388
>gi|154274870|ref|XP_001538286.1| conserved hypothetical protein [Ajellomyces capsulatus NAm1] >gi|150414726|gb|EDN10088.1| conserved hypothetical protein [Ajellomyces capsulatus NAm1] (528 aa)
Score = 309, Expect = 1.5e-26, Identities = 67/208 (32%), Positives = 115/208 (55%)
  Q:    88 NPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKN--KKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKP 295
           N L + +++ H  YL+NL     +      +  + ++ R  ++  KL   HPG+   +    +++ +A  L  A++AT   V+  +ETM G G+ +G        +++ + +  + RIG+C+DTCH   +G D+  P   +  +EEF K + L Y++  HLNDSK  +GSR+D H NIG G +G        ++++L  +P ILETP   D+P
  S:   170 NSLYIGHVLPHGSYLVNLAQEDPTKAKQAYDSFLDDLKRCEELGIKLYNFHPGATNKASLESSLSRLAQALVSALKATTT-VVPVLETMCGHGTTIGGPLSHFKSLLALIPDTYRSRIGICVDTCHSFAAGYDLRSPSSWNNFMEEFDKEVGLQYLRAFHLNDSKTPLGSRRDLHANIGTGFLGLRAFHNLMNDKRLEGIPMILETPI--DRP 379
>gi|119469254|ref|XP_001257929.1| DNA (apurinic or apyrimidinic site) lyase, endon uclease [Neosartorya fischeri NRRL 181] >gi|119406081|gb|EAW16032.1| DNA (apurinic or apyrimidinic site) lyase, endon uclease [Neosartorya fischeri NRRL 181] (561 aa)
Score = 308, Expect = 1.9e-26, Identities = 76/242 (31%), Positives = 125/242 (51%)
  Q:    54 GNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGV--KNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKP 295
           GN F +F    + +    L  +  D+  ++  E      ++I+ H  YL+NL    +       +  + ++ R   +   L   HPGSA  S    A++ +A  L  A+EAT   V+  +ETM G G+ +G    E   +++ +  ++  RIG+C+DTCH   +G D+S P      ++EF   + L Y++ +HLNDSK   GS++D H NIG G +G        ++ +L  +P ILETP   D+P
  S:   160 GNSFALFLKSQRKWENPPLQDDHRDQFRQMCLEHKYDGAKHILPHGSYLVNLAQEDKVKAKQAYDSFLDDLRRCEALGITLYNFHPGSANQSSLPDALSRLAKALTNALEATST-VVPVLETMCGHGTTIGGYLPEFRDLLALIPREHHPRIGICIDTCHSFAAGYDLSSPAGYQSFMKEFEDQIGLQYLRALHLNDSKAPRGSKRDLHANIGTGFLGLRAFHNIMNDPRLEGLPMILETPI--DRP 403
>gi|159898151|ref|YP_001544398.1| apurinic endonuclease Apn1 [Herpetosiphon aurantiacus ATCC 23779] >gi|159891190|gb|ABX04270.1| apurinic endonuclease Apn1 [Herpetosiphon aurantiacus ATCC 23779] (293 aa)
Score = 308, Expect = 2.1e-26, Identities = 63/200 (31%), Positives = 106/200 (53%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI-EATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK 294
           ++ H  YLINLGSP        +    VE+ R  Q+    +V HPG+ + S     ++ +   L + + E    +  I +E  AG+G+ +G +FE +++++       R+G+C DTCH   +G D    +    T + F + + +  ++  HLNDSKN++GSR DRH +IG G VG +      ++ +   +P  LETP   D+
  S:    64 LIAHDSYLINLGSPDNGLWEKSIAAFRVELERCQQLGVGSLVTHPGAHVGSGEAAGLDRVGAALRRLLAEDVGGETQILLEITAGQGTALGHSFEHLARLIELCDGHPRLGICFDTCHGLAAGYDFRTAEGYQTTFDHFDRLIGIDRLRAFHLNDSKNDLGSRVDRHTHIGEGFVGLEGFELIMNDPRFQTIPMALETPKEPDE 267
>gi|68074821|ref|XP_679327.1| AP endonuclease 1 [Plasmodium berghei strain ANKA] >gi|56500052|emb|CAH96514.1| AP endonuclease 1, putative [Plasmodium berghei] (559 aa)
Score = 308, Expect = 2.3e-26, Identities = 69/171 (40%), Positives = 103/171 (60%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKV 265
           I+ H  YLINL +P +  R       + +I R  Q++ KL   HPGS +        I +I+D +N+A + T N VII +E  AG+ + +G  FE +  I+S + +K+RIGVCLDTCH   +G DI      ++ +  F   +D  Y+K +HLNDSK+++GS  DRH+NIG G +
  S:   288 ILPHGSYLINLANPDKEKREKSYLSFVDDIKRCEQLNIKLYNFHPGSTVGMCSTEQGIKNISDCINRAHKETSN-VIIVLENSAGQKNSIGSKFEHLRDIISQIDDKERIGVCLDTCHTFAAGYDIKSYEKFEEVMNNFHNIVDSKYLKAVHLNDSKSDLGSGLDRHENIGKGNI 461
>gi|148265930|ref|YP_001232636.1| apurinic endonuclease Apn1 [Geobacter uraniireducens Rf4] >gi|146399430|gb|ABQ28063.1| Endonuclease IV [Geobacter uraniireducens Rf4] (282 aa)
Score = 306, Expect = 3.3e-26, Identities = 72/216 (33%), Positives = 107/216 (49%)
  Q:    78 DEAVKLMKEK-NPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDV-IICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           D  V L KEK     L  I+ H  YLINL +     R   L     E+ R  ++    IV+HPG+         +  I +  +   E T     +I +ET AG+G+ VG  FE +  I+ G  +  R G+C DTCH   +G DI+         EEF + + +  ++  H+NDSK  +  R DRH++IG G +G        ++ +   +PKILETP  D+
  S:    46 DPDVALFKEKLKESGLHEIISHDIYLINLAAAPGEVRDKSLAGFQEEMERCARLGIGKIVMHPGAHNGDGEETGLRRIVEAFDHLFENTPAYTGMILLETTAGQGTNVGYTFEHLRAIIDGSAHPGRFGICYDTCHTFAAGYDITSEAGYKAVWEEFDRIIGIDRLQCFHINDSKKGLNCRVDRHEHIGQGAIGLSAFRFIMNDPRFVKIPKILETPKGDN 266
>gi|121699342|ref|XP_001267990.1| DNA (apurinic or apyrimidinic site) lyase, endon uclease [Aspergillus clavatus NRRL 1] >gi|119396132|gb|EAW06564.1| DNA (apurinic or apyrimidinic site) lyase, endon uclease [Aspergillus clavatus NRRL 1] (532 aa)
Score = 305, Expect = 5.1e-26, Identities = 75/242 (30%), Positives = 124/242 (51%)
  Q:    54 GNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGV--KNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKP 295
           GN F +F    + +    L  ++ D+  +L  E       +I+ H  YL+NL    ++      +  + ++ R   +   L   HPGSA  S    A+  +A  L  A+EAT   V   +ETM G G+ +G    E   +++ +  ++  RIG+C+DTCH   +G D++ P      +++F   + L Y++ +HLNDSK   GS++D H NIG G +G        ++ +L  +P ILETP   D+P
  S:   143 GNSFALFLKSQRKWDNPPLQDDIRDQFRQLCLEHKYDGARHILPHGSYLVNLAQEDKAKAKQAYDSFLDDLRRCEALGITLYNFHPGSANQSSLADALARLAKALTNALEATST-VTPVLETMCGHGTTIGGYLTEFRDLLALIPREHHARIGICIDTCHSFAAGYDLATPAGYSTFMQDFEDVIGLQYLRALHLNDSKAPRGSKRDLHANIGTGFLGLRAFHNIMNDPRLEGLPMILETPI--DRP 386
>gi|121998447|ref|YP_001003234.1| apurinic endonuclease Apn1 [Halorhodospira halophila SL1] >gi|166920085|sp|A1WXM0|END4_HALHL Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|121589852|gb|ABM62432.1| apurinic endonuclease Apn1 [Halorhodospira halophila SL1] (297 aa)
Score = 302, Expect = 9.4e-26, Identities = 66/195 (33%), Positives = 109/195 (55%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIE--ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           ++ HA YLINL +      +     L  E+ R +Q+  +L+  HPG+ L++     I  IA  LN          DV + +E +AG+GS VG +F E++ I+  ++  +R GVC+DT H   +G ++      D     F  ++ L+ +  +HLNDS+   GSRKDRH  IG G++G +   +   + + A++P++LETP
  S:    64 VMSHASYLINLAATDPEKHAKSQTALEAELERCHQLGIELLNFHPGAHLEAGIEAGIETIAATLNAICRNHPDKTDVCLVLENVAGQGSTVGADFAELAAILERLETPERFGVCVDTAHAFAAGYELHTAAGWDAMWAAFDDHIGLNRLVALHLNDSRPPCGSRKDRHALIGRGEIGPEAFRRAVTDPRTASLPQMLETP 263
>gi|88603044|ref|YP_503222.1| apurinic endonuclease (APN1) [Methanospirillum hungatei JF-1] >gi|88188506|gb|ABD41503.1| Endonuclease IV [Methanospirillum hungatei JF-1] (286 aa)
Score = 302, Expect = 1.1e-25, Identities = 67/240 (27%), Positives = 120/240 (50%)
  Q:    55 NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK 294
           +CF +FT  P+ +  K +++   D  +   ++  P     +  H  YL NL     +     ++ L +E++R   +H   ++ H G A D DR      +   ++ A+E  +   ++ +E  AG+   VG   E++  +    + + RIG+C DTCH   +G D+  P+   Q  ++    + L+ + VIHLND+K ++GS  DRH++IG G +G   +     +    N+P I ETP  D +
  S:    32 DCFQIFTKNPRGWKAKPIEKPDSDAFIHESEQFRP---GTVYAHISYLPNLAGDNSAMYEKSVDALRMELDRCQALHIPYLITHLGHAGD-DRAHGRARVVQAIDTALEGREPGTMLLLENTAGEKHSVGSTIEDIGDVFGRCEEQNRIGICFDTCHAFAAGYDLRTPELVGQVADQIQDTIGLTSLHVIHLNDAKGDLGSGLDRHEHIGMGTLGVPGIRSVLMHPGFRNIPCICETPVDDRR 270
>gi|15606736|ref|NP_214116.1| deoxyribonuclease IV [Aquifex aeolicus VF5] >gi|8928092|sp|O67551|END4_AQUAE Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|2983967|gb|AAC07514.1| deoxyribonuclease IV [Aquifex aeolicus VF5] (282 aa)
Score = 299, Expect = 2.0e-25, Identities = 80/265 (30%), Positives = 136/265 (51%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETL----EYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKE-KNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI-EATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           L G+HV         GS+L+T     +     F  F   P+ +  K +D+      ++ +K+ KNP     ++VHAPYL+NL SP E  R   +   + E+   +++       HPG+A        + ++  +L +   E T     + +E  AG+  ++G NF+E+ +I++  +  K +GVCLDTCH    G +I+  +       E  K + L  +K +H NDSK  +G RKDRH++IG G +G +       +E  + +P  +ETP  ++
  S:     3 LFGAHVSS------AGSILKTFKRAKDIGAEVFQFFLRSPRAWYWKGVDKETKQAFIEKLKDFKNP-----VMVHAPYLLNLASPNEELREKSVKVFLEELKFCDEVGIHFYNFHPGTAKGISDEEGLRNVIKSLEEVFSEYTPKFTTVLLENTAGERGDLGKNFKELKEIMNVFRGIK-LGVCLDTCHAFAYGYEINTKEGFENFKREIEKMVGLESVKAVHANDSKVPLGGRKDRHEHIGKGYIGLEGFKNLLKDEYFSTLPYYIETPKENN 264
>gi|115398874|ref|XP_001215026.1| conserved hypothetical protein [Aspergillus terreus NIH2624] >gi|114191909|gb|EAU33609.1| conserved hypothetical protein [Aspergillus terreus NIH2624] (413 aa)
Score = 299, Expect = 2.1e-25, Identities = 76/243 (31%), Positives = 120/243 (49%)
  Q:    54 GNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNK--KRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPI 296
           GN F +F    + +    L  +  D    L  E      ++I+ H  YL+NL    ++      +  + ++ R   +  KL   HPGSA  S    A++ +A  L  A+ AT   V   +ETM G G+ +G    E   +++ +  +   RIG+C+DTCH   +G D+  P      ++EF   + L Y++ +HLNDSK   GSR+D H NIG G +G        +  +   +P ILETP   D+P+
  S:    32 GNAFALFLKSQRKWDNPALQDDHRDNFRNLCIEHQYDGAKHILPHGSYLVNLAQEDKAKAKQAYDAFLDDLRRCEALGIKLYNFHPGSANQSPLPEALSRLAKALTNALAATTT-VTPVLETMCGHGTTIGGYLPEFRDLLALIPREYHSRIGICIDTCHSFAAGYDLVSPAGFRAFMQEFDDVIGLQYLRALHLNDSKAPRGSRRDLHANIGTGFLGLRAFHNIMNEPRFEGLPMILETPI--DRPV 276
>gi|71003578|ref|XP_756455.1| hypothetical protein UM00308.1 [Ustilago maydis 521] >gi|46096060|gb|EAK81293.1| hypothetical protein UM00308.1 [Ustilago maydis 521] (552 aa)
Score = 299, Expect = 2.2e-25, Identities = 83/262 (31%), Positives = 143/262 (54%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGP-------------PQNFMRKELDQNLIDEAVKLMKEKNPLLLEN-------------IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGS------------------ALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSE--VGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLD----LSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           L +G+H+   +   +  + L  L   GN F  F  P              + F +  +  + +  A+ + KE++   +E              +V H  YL+NL +P ES R       I ++ R  Q+  +L   HPGS                   + + +  A   +A  +N+A   T + VII +E MAG  ++  +G +  +++ I+SGV++K R+GVC+DTCH   +G D++ P      F++ +D       ++  HLNDSK  +  ++DRH NI  G +G        ++++   +P ILETP
  S:   157 LFIGAHI--SSAGGVENAPLNALRIGGNAFSCFVRPKMQWASNPIRDTSAEQFKQHVMQHSFMPAALSVKKEQD---IEQETHRLSDVEEYGYVVPHGCYLVNLANPDESKREKSFQAFIDDLQRCEQLGIRLFNFHPGSMTVASIYGEEPPDVGPRSEVRAAKADACALVASYINRAHSLTSS-VIILIENMAGSKNDTILGSSLADLASIISGVQDKSRVGVCIDTCHAFAAGYDLTTP-AAYATFTELIDSKIGWQTVRAFHLNDSKFPLACKRDRHANIARGHIGLGGFWNIVNDQRWNGIPLILETP 461
>gi|1173614|gb|AAC28163.1| Spapn1 [Schizosaccharomyces pombe] (323 aa)
Score = 298, Expect = 3.1e-25, Identities = 74/209 (35%), Positives = 122/209 (58%)
  Q:    93 ENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQ-----------IHSKLIVL-------------HPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           + ++VH  YLIN+ +  E  R    N  + ++ R  +           IHS L +L              PGS     +   IN++A+ +N+A E T + VII  E MAG+G+ +G  F++ + + S +KN  R  VCLDTCH   +G DI   +   + ++EF + +   Y+   HLNDSK  +GS +D H+NIG G +G +      ++ +   +P +LETP +  +  +K+E+
  S:    56 KQVLVHGSYLINMANADEQKREQAFNCFVDDLKRCERLGVGLYNFQYVIHSVLYLLIFYPKRTNSFDLCSPGSTASCTKEEGINNLAECINRAHEETKS-VIIVTENMAGQGNCLGGTFDDFAALKSKIKNLDRWRVCLDTCHTFAAGYDIRTEESYKKVIDEFDEKVGAKYVSGWHLNDSKAPLGSNRDLHENIGLGFLGLEPFRLIMNDSRWDGIPLVLETPAKSPEQ-WKKEV 289
>gi|6682103|gb|AAF23271.1|AF101263_1 probable endonuclease IV [Staphylococcus aureus] (131 aa)
Score = 297, Expect = 3.4e-25, Identities = 58/119 (48%), Positives = 85/119 (71%)
  Q:   191 SKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY-----RDDKPIYKQEIINLNSKEW 309
           ++I+ GV N +R+ VC DTCH HD+G ++  D D  L EF K + +  IKV+H+NDSKN+ G++KDRH+NIG+G +GFD L    H++   ++PKILETPY     ++ KP YK EI  L  +++
  S:     1 ARIIDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSKNDRGAQKDRHENIGFGYIGFDALNYIVHHDSFKDIPKILETPYVGEDKKNKKPPYKLEIEMLKQQQF 125
>gi|114320888|ref|YP_742571.1| endonuclease IV [Alkalilimnicola ehrlichei MLHE-1] >gi|114227282|gb|ABI57081.1| Endonuclease IV [Alkalilimnicola ehrlichei MLHE-1] (296 aa)
Score = 294, Expect = 9.4e-25, Identities = 71/235 (30%), Positives = 122/235 (51%)
  Q:    55 NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEA--TDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           +C  +FT   + +  K +     +EA      +    +  ++ HA YL+NLG+      +   +    E+ R +++  +L+  HPG+ +       I  IA  LN+   A     DV + +E +AG+G+ +G +FEE+  I+  +++ +R GVC+DT H   +G  I      ++T  EF + L L  +  +HLNDSK    SRKDRH  IG G++G +   +   + +  ++P  LETP
  S:    26 DCIQIFTRNQRQWRVKPISD---EEATAFRANREACGIGAVMSHASYLLNLGTTDPEKFAKTYDAFEQELLRCHKLGVELLNFHPGAHVGKGVETGIQQIAHALNEICRAHPDKTDVCLVLENVAGQGTTLGRSFEELRAILDLLESPERFGVCVDTAHAFAAGYPIHTEAGWEKTWSEFDRILGLDRLVALHLNDSKVPFDSRKDRHALIGRGEIGAEAFRRAVTDPRTRHLPMFLETP 262
>gi|29832633|ref|NP_827267.1| endonuclease IV [Streptomyces avermitilis MA-4680] >gi|39931078|sp|Q82AG6|END4_STRAW Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|29609753|dbj|BAC73802.1| putative endonuclease IV [Streptomyces avermitilis MA-4680] (310 aa)
Score = 292, Expect = 1.4e-24, Identities = 68/193 (35%), Positives = 109/193 (56%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIE--ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           VHAPYLIN GS  E+T    +  L   + R  +I +  +V+H GSA    +R+VA+  + ++L   ++    D+D  + +E+ AG+G+ +     +       +    ++GVCLDTCH+  +G D++ P    QTL+     +    +K+IH NDSK+ +G+ KDRH+NIG G +G D       +     VP I+ETP
  S:    93 VHAPYLINFGSHTEATVEKSVESLRHSLRRGREIGALGVVVHTGSATGGRERSVALAQVREHLLPLLDELTHDDDPYLLLESTAGQGASLCSRTWDFGPYFEALDAHPKLGVCLDTCHIFAAGHDLTGPSGMHQTLDLLVDTVGEGRLKLIHANDSKDVVGAHKDRHENIGSGHIGEDPFRALMTHPATEGVPLIIETP 291
>gi|188997638|ref|YP_001931889.1| apurinic endonuclease Apn1 [Sulfurihydrogenibium sp. YO3AOP1] >gi|188932705|gb|ACD67335.1| apurinic endonuclease Apn1 [Sulfurihydrogenibium sp. YO3AOP1] (279 aa)
Score = 291, Expect = 1.9e-24, Identities = 75/216 (34%), Positives = 115/216 (53%)
  Q:    78 DEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATD-NDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSK----YLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           +E  + +++KN   +  +VVHA YL NL S +E      +  +I E+    ++     V+H G +  + +  AI+ I     +     +  +    VET+AG+  EVG   EEV  ++   +N+K IGVCLDTCH+  SG  I + D+    F K    Y  L   KVIH NDSK    S+KDRH++IG G +G +    + +++    +P ILETP   D
  S:    47 EEKERFLQKKNEYKIHPLVVHASYLFNLASFEEELYKKSIESVIQELKLCEELKIDYYVIHAGKSKGNPKKQAIDRILRAFEEIFSRLNLKNTTFLVETLAGQSGEVGATLEEVYTLIEPFENEK-IGVCLDTCHIFASGYQI-NTDEGFNSFKKELIDYNLLEKTKVIHCNDSKAPFNSKKDRHEHIGKGFIGLEGFRIFLNDDDFNKLPFILETPKEGD 265
>gi|182439183|ref|YP_001826902.1| putative endonuclease [Streptomyces griseus subsp. griseus NBRC 13350] >gi|178467699|dbj|BAG22219.1| putative endonuclease [Streptomyces griseus subsp. griseus NBRC 13350] (290 aa)
Score = 288, Expect = 3.8e-24, Identities = 65/193 (33%), Positives = 110/193 (56%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIE--ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           VHAPYLIN GS  E+T    +  L   + R  +I +  +V+H GSA     R  A+  + +++   ++    D+   + +E+ AG+GS +     +       + +  ++G+CLDTCH++ +G D++ P    QTL+   + +    +K+IH NDSK+ +G+ KDRH+NIG G +G +   +   +   A VP I+ETP
  S:    70 VHAPYLINFGSHTEATVEKSVESLRHSLRRAREIGALGVVVHTGSATGGRPRATALAQVREHMRPLLDELTHDDSPDLLLESTAGQGSSLCSRTWDFGPYFEALDSHPKLGICLDTCHIYAAGHDLAGPSGMRQTLDLLVETVGEGRLKLIHANDSKDVVGAHKDRHENIGAGHIGVEPFRELFAHPATAGVPLIIETP 268
>gi|110667379|ref|YP_657190.1| endonuclease IV [Haloquadratum walsbyi DSM 16790] >gi|121684932|sp|Q18KA6|END4_HALWD Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|109625126|emb|CAJ51545.1| endonuclease IV [Haloquadratum walsbyi DSM 16790] (278 aa)
Score = 288, Expect = 3.9e-24, Identities = 74/267 (27%), Positives = 144/267 (53%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLL-LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATD-----NDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK 294
           +L+G+H        +  +V   LE  GNC  +FT  PQ +    +D    D   +  ++++ +  +   V+H+ YL+NL +PK+  R+  ++ +  E++   Q+    + +H G+   + +          L+ AI A D     + V + +E+ AG G+++G  F+ ++ ++   ++   + VCLDT H+  +G D+S P   + T++EF   + +  +  +HLNDSK+  G+ KD H +IG GK+G   +  + ++  +  +P +LETP  + K
  S:     1 MLVGAHESIAGG--VANAVDRQLENGGNCGQIFTHSPQVWQDPSID----DTDAEAFRDRSQMHDIGPWVIHSSYLVNLCTPKDDLRAKSIDSMQQEVDAAAQLSIPYVNVHLGAHTGAGKQ-------QGLDNAISALDELTIPDSVTVLLESDAGSGTKLGNKFDHLAYVLE--ESTHELEVCLDTAHVFAAGYDLSTPAAVNTTIKEFDTTVGVDNLACVHLNDSKHACGTNKDEHAHIGEGKIGESGMEAFINHSAIDPIPLVLETPNENGK 261
>gi|145617995|ref|ZP_01774057.1| apurinic endonuclease Apn1 [Geobacter bemidjiensis Bem] >gi|144945738|gb|EDJ80801.1| apurinic endonuclease Apn1 [Geobacter bemidjiensis Bem] >gi|197086116|gb|ACH37387.1| apurinic endonuclease Apn1 [Geobacter bemidjiensis Bem] (283 aa)
Score = 286, Expect = 6.5e-24, Identities = 68/213 (31%), Positives = 105/213 (49%)
  Q:    92 LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI-EATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           L ++V H  YLINL +     +   L     E+ R   +    IV+HPGS         I  I +  ++   E  +    + +E  AG+G+ +G  F+ +  I+ G     R GVC DTCH   SG  I+D D   +T +EF   L +  +   HLNDSK  +G + DRH++IG G +G +      ++     VPK +ETP  D     + +++NL
  S:    61 LSHVVSHDIYLINLAAAPGEVKDKSLIAFKEEMQRCAALGIDKIVMHPGSHTGDGEETGIRRICEAFDQLFAEVPEFTGKVLLENTAGQGTNLGYRFDHLKSIIEGSSYPTRFGVCFDTCHAFASGYPIADRDGYRRTFDEFDSALGIDKLMAFHLNDSKKGLGCKVDRHEHIGAGALGLEPFRFILNDPHFKLVPKFIETPKGDAD---EMDVVNL 274
>gi|148508096|gb|ABQ75891.1| endonuclease IV [uncultured haloarchaeon] (278 aa)
Score = 286, Expect = 6.7e-24, Identities = 74/267 (27%), Positives = 143/267 (53%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLL-LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATD-----NDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDK 294
           +L+G+H        +  +V   LE  GNC  +FT  PQ +    +D    D   +  ++++ +  +   V+H+ YL+NL +PK+  R+  ++ +  E++   Q+    + +H G+   +            L+ AI A D     + V + +E+ AG G+++G  F+ ++ ++   ++   + VCLDT H+  +G D+S P   + T++EF   + +  +  +HLNDSK+  G+ KD H +IG GK+G   +  + ++  +  +P +LETP  + K
  S:     1 MLVGAHESIAGG--VANAVDRQLENGGNCGQIFTHSPQVWQDPSID----DTDAEAFRDRSQMHDIGPWVIHSSYLVNLCTPKDDLRAKSIDSMQQEVDAAAQLSIPYVNVHLGAHTGAGEQ-------QGLDNAISALDELTIPDSVTVLLESDAGSGTKLGNKFDHLAYVLE--ESTHELEVCLDTAHVFAAGYDLSTPAAVNTTIKEFDTTVGVDNLACVHLNDSKHACGTNKDEHAHIGEGKIGESGMEAFINHSAIDPIPLVLETPNENGK 261
>gi|115649163|ref|XP_001178092.1| PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] >gi|115673306|ref|XP_792111.2| PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] (148 aa)
Score = 286, Expect = 6.8e-24, Identities = 58/138 (42%), Positives = 85/138 (61%)
  Q:   169 VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNS 306
           +I  +E M+ +G  +G +FEE+  I+  VK+K RIGVCLDTCH   +G D+S      + + EF + +   Y+K +HLNDSK  +G   DRH+NIG GK+G +   +  ++ +  N+P ILETP       Y +EI  LNS
  S:     8 LIAVIENMSRQGHTIGGDFEELRGIIDRVKDKSRIGVCLDTCHAFAAGYDLSTESGYKKMMAEFERVIGFQYLKGVHLNDSKGAVGCHLDRHENIGKGKIGLEGFRRLMNDPRFDNIPLILETPIEFG---YAKEIKTLNS 145
>gi|78044027|ref|YP_360577.1| endonuclease IV [Carboxydothermus hydrogenoformans Z-2901] >gi|123575940|sp|Q3ABA7|END4_CARHZ Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|77996142|gb|ABB15041.1| endonuclease IV [Carboxydothermus hydrogenoformans Z-2901] (283 aa)
Score = 286, Expect = 8.1e-24, Identities = 71/246 (28%), Positives = 134/246 (54%)
  Q:    59 VFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTL---EEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINL 304
           +F+  P+    K  ++    E    ++ K    L  +VVH PY++NL SP+E      +  +  ++ R++Q+H+  +V+H GS   +     +  + + L K + + +    I +E  AG G+E+G + + ++ I+S   +++ +G+CLDTCH+  +G D   P+       EF + +      ++H+NDSK+ IGSRKDRH+N+  G +G +  +   ++     VP ILETP    +P  +++++ L
  S:    30 IFSRSPRGGEAKPFNEK---ELKGFLEFKEEYKLYPLVVHVPYVMNLASPEEEMFQKSVAMIREDLYRSDQLHADFLVVHVGSHRGAGEERGLARMVEGL-KILLSENFKTRILIENTAGSGNEMGYSLDHLAYIISETGHEE-LGICLDTCHLLAAGYDDVSPEGISAFSREFREKIGEERFCLLHVNDSKHPIGSRKDRHENLEQGYIGREGFINLLNSPFFKRVPWILETP----EPGIEEDLVKL 269
>gi|168704122|ref|ZP_02736399.1| apurinic endonuclease Apn1 [Gemmata obscuriglobus UQM 2246] (291 aa)
Score = 285, Expect = 8.8e-24, Identities = 63/200 (31%), Positives = 102/200 (51%)
  Q:    92 LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI-EATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDIS---DPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR 291
           L  I VH  YLINL SPK+   +  +     E+ R   + +  +V HPG+   S     +  +     +A+       V + +ET AG+GS +G  FE ++ ++       R+GVC DTCH+  +G  ++   D   T ++F   + L  + + H+NDS+   GSR DRH  IG G++G     +   + +  + P ILETP +
  S:    61 LHWITVHDSYLINLASPKDELFAKSVAAFADELERAEALGADYLVTHPGAHTGSGEEAGLERVVAGYEEALARCPGYKVRVLLETTAGQGSSLGYRFEHLATVLDRANCADRMGVCFDTCHVFAAGYGLATAEDYAATFQQFDDLVGLERLNLFHMNDSEKPRGSRVDRHAGIGAGEIGEAAFRRLVTDVRFRDRPMILETPKK 264
>gi|51891597|ref|YP_074288.1| putative endonuclease IV [Symbiobacterium thermophilum IAM 14863] >gi|59797720|sp|Q67S99|END4_SYMTH Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|51855286|dbj|BAD39444.1| putative endonuclease IV [Symbiobacterium thermophilum IAM 14863] (276 aa)
Score = 284, Expect = 1.3e-23, Identities = 71/237 (29%), Positives = 113/237 (47%)
  Q:    57 FMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSY---IKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           F  FT  P+ F  K  D         LM E   +     V HAPY+ NL +P    +++ +  L  ++       +   V H G  +          + + LN+ +EA      + +E  AG GSE+G + EE+ ++ S V+  +RI  C DTCH   +G  I  P+   +  +    + Y   ++ +HLNDSK + GSRKDRH N+G G +G   +     +     +P +LETP +D+
  S:    28 FQFFTKNPRGFKGKSADPEAAARGRALMAEYGLV----AVAHAPYITNLSTPDPELQAISIASLKQDLENAEAYGAIGCVCHMGKHVGEGEAYGRARMVETLNRLLEAYTGSCPLLLENTAGMGSELGTHLEELMEVRSRVEQPERIAFCFDTCHAFAAG--IYRPEDWEDFVAHARAIGYWGLLRAVHLNDSKFDHGSRKDRHANLGKGFLGEAGIATLLRSGAFEGLPVVLETPVKDE 261
>gi|191163311|ref|ZP_03025186.1| apurinic endonuclease Apn1 [Geobacter sp. M21] >gi|190995518|gb|EDV70971.1| apurinic endonuclease Apn1 [Geobacter sp. M21] (283 aa)
Score = 283, Expect = 1.8e-23, Identities = 65/201 (32%), Positives = 100/201 (49%)
  Q:    92 LENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI-EATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRD 292
           L +++ H  YLINL +     +   L     E+ R   +    IV+HPGS      +  I  I +  ++   E       + +E  AG+G+ +G  F+ +  I+ G     R GVC DTCH   SG  I+D D   +T +EF + L +  +   HLNDSK  +G + DRH++IG G +G +      ++     VPK +ETP  D
  S:    61 LSHVMSHDIYLINLAAAPGEVKDKSLIAFKEEMQRCAALGIGKIVMHPGSHTGDGEDTGIRRICEAFDQLFGEVPQFTGKVLLENTAGQGTNLGYRFDHLKAIIEGSSYPTRFGVCFDTCHAFASGYPIADRDGYRRTFDEFDRALGIDKLMAFHLNDSKKGLGCKVDRHEHIGAGALGLEPFRFILNDPHFKLVPKFIETPKGD 265
>gi|94968354|ref|YP_590402.1| endonuclease IV [Acidobacteria bacterium Ellin345] >gi|94550404|gb|ABF40328.1| Endonuclease IV [Acidobacteria bacterium Ellin345] (328 aa)
Score = 282, Expect = 2.3e-23, Identities = 73/242 (30%), Positives = 134/242 (55%)
  Q:    55 NCFMVFTGPPQNFMRKELDQNLID--EAVKLMKEKNPLLLENIVVHAPYLINL--GSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEA---TDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNE-KLANVPKILETPYRDDKPI 296
           +C  +F+  P+ +   EL ++  +   +++   + NPL     V+HA YLIN+  G+P+   +S+       E+ R   + +  +VLHPGS   + R   +   A+ +  A++       ++ I +E  AG    +G +FE+V+++++ ++    +  C+DTCH H +G DI+     ++TL++    + L  + V H ND+K   GS+ DRH +IG G +G +   KW  N+ +L +   I ETP   D+P+
  S:    54 SCLQIFSSSPRQWKPFELGRSQCETMSSIRAKYDLNPL-----VIHANYLINVAGGNPEFHQKSI--EAFRAEVQRGIDLCADYLVLHPGSFKGATREDGLQRAAEAIEAAVDGLGIEKTNLKITIENTAGSEFSLGGSFEQVAELMARLRKHVPVAACIDTCHTHVAGYDITTKKGFEKTLQQLDDTVGLKNVGVFHCNDAKAPRGSKLDRHQHIGQGTIGLEPF-KWLLNDPRLQHPAFIAETPI--DEPL 296
>gi|115378709|ref|ZP_01465857.1| apurinic/apyrimidinic endonuclease [Stigmatella aurantiaca DW4/3-1] >gi|115364295|gb|EAU63382.1| apurinic/apyrimidinic endonuclease [Stigmatella aurantiaca DW4/3-1] (265 aa)
Score = 281, Expect = 2.5e-23, Identities = 61/194 (31%), Positives = 104/194 (53%)
  Q:    96 VVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN-DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           + H  YL+NLG+     R   +  +  E+ R  ++    +V+HPG+  D  R +A+  +A+ L++    T      IC+E  AG+G  +G  F  +++I+S V  + R+G+CLDTCH+  +G D+S     +  + E    + L  ++  HLND K  +G R DRH+ +G G +G        ++ +  N   +LETP
  S:    51 IAHGSYLVNLGTEDPVLRDKSIACVTEELTRCERLGISCLVIHPGTHPDEKRGLAL--VAEGLDEVHRRTPRFRSRICLEITAGQGHCLGWRFWHLTEILSRVSREDRLGLCLDTCHLFAAGYDLSSEEGYEAVMAECDAAVGLERVRCFHLNDCKKPLGCRVDRHEEVGQGTIGRTAFRCLVNDSRFVNTIGVLETP 246
>gi|72162355|ref|YP_290012.1| endonuclease IV [Thermobifida fusca YX] >gi|71916087|gb|AAZ55989.1| Endonuclease IV [Thermobifida fusca YX] (293 aa)
Score = 281, Expect = 3.0e-23, Identities = 65/195 (33%), Positives = 103/195 (52%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVI-ICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           + VHA YLINLGSP E   +  +  L   + R  QI ++ +V+H GSA+   R   +  +   L   +EA D     + +E MAG+G  +    ++++  +  V    + GVCLDT H+  +G D+S        L+ F + +    ++++H NDS    GSR+DRH  IG G +G D   +   +   A VP ++ETP
  S:    66 VFVHACYLINLGSPDEEIAARSVASLKYTLQRAAQIGARGVVVHTGSAVRGGRAAGLARVRARLLPILEALDEAAPPVLLEPMAGQGQVLCATVDDLADYLDAVDRHPKAGVCLDTAHVFGAGHDVSTRAGMRTMLDRFGEVVGADRLRLVHANDSAAPCGSRRDRHAGIGLGYIGADPFAEVFTHPVSAGVPVVVETP 264
>gi|59712721|ref|YP_205497.1| endonuclease IV [Vibrio fischeri ES114] >gi|59480822|gb|AAW86609.1| endonuclease IV with intrinsic 3'-5' exonuclease activity [Vibrio fischeri ES114] (223 aa)
Score = 276, Expect = 9.4e-23, Identities = 64/195 (32%), Positives = 112/195 (57%)
  Q:    54 GNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKN 248
            N F +FT   + ++ K L + +I +  K   ++     E I+ H  YLINLG+P+           I E+ R +Q+   L+  HPGS L     +  I+ IA+++N A +A   DV+  +E  AG+G+ +G  FE++++I+  V++K R+G+C+DTCH   +G D+S     + T  EF + +  S ++ +H+ND+K+
  S:    26 ANAFALFTKNQRQWVAKPLTKKIISD-FKANCKRFGFSSEQILPHDSYLINLGAPETEKLEKSRAAFIDEMERCHQLGLTLLNFHPGSHLKKISEDECISLIAESINFAHQAVP-DVVAVIENTAGQGTNLGWKFEQLAQIIEQVEDKSRVGICIDTCHTFAAGYDLSSKEACEHTFAEFERIVGSSNLRGMHINDAKS 222
>gi|83589972|ref|YP_429981.1| endonuclease IV [Moorella thermoacetica ATCC 39073] >gi|123524591|sp|Q2RJF1|END4_MOOTA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|83572886|gb|ABC19438.1| Endonuclease IV [Moorella thermoacetica ATCC 39073] (279 aa)
Score = 273, Expect = 2.3e-22, Identities = 79/272 (29%), Positives = 136/272 (50%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKA-IEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           LG+H+   AK     + + T     N F  FT  P+    +++    I    +  +  +   L  I  H PY +NLG+  E  +      L  +  R   I  + ++ HPG   + +R   ++ I   + +A +  T    ++ +ETMAG+G EVG   +++  I+ G+    R+GVCLD+ H+  +G D+  P    Q ++E +  + L  +K +HLNDS   +GS +DRH  IG G++G + +    ++  L  +P  LETP  + +  Y +EI
  S:     3 LGAHLSI-AKGLPRTAAMAT-SIGANTFQYFTRNPRGGAARQIPGKEIQAWREARRRAD---LYPIAGHLPYTVNLGAAAERQQEFTRMVLHDDTLRVAAIDGEYLISHPGH-YEGERQAGLDRIIQLIEEAYLSITPPGPMLLLETMAGQGKEVG-TIDDLCYILEGLGWPDRVGVCLDSAHLFAAGWDLRTPAGCQQLVQELAAKIGLDRVKAMHLNDSAAPLGSHRDRHAGIGKGELGREGIAAVVNDPFLGELPLFLETPVANYEE-YGEEI 270
>gi|194341526|gb|EDX22492.1| endonuclease IV [Streptomyces sp. Mg1] (295 aa)
Score = 272, Expect = 3.1e-22, Identities = 64/193 (33%), Positives = 104/193 (53%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIE--ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           VHAPYLIN GS   +T    +  L   + R   I +  +V+H GSA     R  A   + +++   ++    D+D  + +E+ AG+GS +     +       + +  ++G+CLDTCH+  +G D+++P    QTL+     +    +K+IH NDSK  +G+ KDRH NIG G +G +   +   +     VP I+ETP
  S:    77 VHAPYLINFGSHTVATVEKSVESLRHSLRRARAIGALGVVVHTGSATGGRPREAAYAQVREHMLPLLDELTHDDDPFLLLESTAGQGSSLCSRTWDFGPYFEALDHHPKLGICLDTCHIFAAGHDLAEPGGTKQTLDLLVDTVGEGRLKLIHANDSKEGVGAHKDRHANIGQGHIGREAFAELFTHPATEGVPLIIETP 275
>gi|188584796|ref|YP_001916341.1| apurinic endonuclease Apn1 [Natranaerobius thermophilus JW/NM-WN-LF] >gi|179349483|gb|ACB83753.1| apurinic endonuclease Apn1 [Natranaerobius thermophilus JW/NM-WN-LF] (284 aa)
Score = 272, Expect = 3.2e-22, Identities = 74/234 (31%), Positives = 118/234 (50%)
  Q:    56 CFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQ---TLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKV---GFDYLVKWAHNEKLANVPKILETP 289
           C  +F+G P ++   ++     D  +K  +E   L ++ +V H PYLINL SPK   R   +  L   + +     +  +V H GS +       I+ ++ +L K +E     V + +E  +G GS +G +  E+ KI+      + +G C DT H   +G DIS+  +   TLE  ++ L L  IKV H ND+   +GS KDRH +IG G +   GF  L+    ++       I+ETP
  S:    27 CIQIFSGNPTSWKPGKITPKSRDLFIKKQEE---LQIKPLVFHTPYLINLASPKNDIREKSIYLLNAALEKAKAYDAPYVVTHIGSHVGEGVEKGIDLVSYSLEKIMEDWPEGVELLLENTSGAGSTLGGSLTELKKIIDKFSGTQVLGCCFDTAHAWGAGYDISNVKEVETTLELVNEQLGLDLIKVCHANDTNVPLGSTKDRHQHIGEGNITDEGFGALLT---HDSFTPKAVIMETP 260
>gi|117928193|ref|YP_872744.1| endonuclease IV [Acidothermus cellulolyticus 11B] >gi|117648656|gb|ABK52758.1| Endonuclease IV [Acidothermus cellulolyticus 11B] (287 aa)
Score = 271, Expect = 4.3e-22, Identities = 70/230 (30%), Positives = 123/230 (53%)
  Q:    59 VFTGPPQNFMRKELDQNLIDEAVKL-MKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSD-RNVAINHIADNLNKAIEATDND-VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILET 288
           VF   P+ + R   D  +  E  +L    + P     + VHAPYL+NLGSP  +T    +  +   + R   I ++ IV+H GSA+ S  R++A   + + L   ++    D  ++ +E  AG G  +    E++   +  V+   R+G+C+DTCH+  +G DI+ P     TL    + +    +K++H ND+K E+GS++D H+ IG G++G +   +   +   + +P +LET
  S:    37 VFVSNPRGWARPPADPRVDGEFRELCAAARIP-----VFVHAPYLVNLGSPTPTTLENSVLAVRYTLARAAAIGARGIVVHAGSAVSSSGRDLAAKQVREALLPILDEIPEDGPLLLIEPTAGGGQSLASRIEDLPAYLENVEAHPRLGICIDTCHLFAAGHDIASPGGMRATLNALIRAIGRRRLKLVHANDAKAELGSQRDAHERIGRGRIGVEPFRELFRHPATSGIPIVLET 267
>gi|21220589|ref|NP_626368.1| endonuclease [Streptomyces coelicolor A3(2)] >gi|10719986|sp|Q9S2N2|END4_STRCO Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|5689921|emb|CAB51959.1| putative endonuclease [Streptomyces coelicolor A3(2)] (294 aa)
Score = 269, Expect = 6.9e-22, Identities = 64/193 (33%), Positives = 105/193 (54%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIE--ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           VHAPYLIN GS   +T    +  L   + R   I +  +V+H GSA    +R VA+  + +++   ++    D+D  + +E+ AG+G+ +     +       +    ++GVCLDTCH+  +G D++ P    QTL+     +    +++IH NDSK+  G+ KDRH+NIG G +G D       +     VP ++ETP
  S:    77 VHAPYLINFGSHTGATVERSVESLRHSLRRGRAIGALGVVVHTGSATGGRERPVALKQVREHMLPLLDELTHDDDPYLLLESTAGQGASLCSRTWDFGPYFEALDAHPKLGVCLDTCHIFAAGHDLTGPSGMHQTLDLLVDTVGEGRLRLIHANDSKDVAGAHKDRHENIGAGHIGEDPFRALMTHPATDGVPLVIETP 275
>gi|46579635|ref|YP_010443.1| endonuclease IV [Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough] >gi|59797791|sp|Q72CQ9|END4_DESVH Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|46449050|gb|AAS95702.1| endonuclease IV [Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough] (282 aa)
Score = 269, Expect = 7.3e-22, Identities = 68/264 (25%), Positives = 130/264 (49%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDV-IICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRD 292
           L G+H+   A   +  ++ + +E  G    +FT   + +  K   +      V+    +       +  HA YLIN+ +   +  +  +  L+ E  R   +    +VLHPG+ L + R   I   A N+++  +       ++ +E  AG+G+ +G +  ++++I+   ++  ++GVCLDT H   +G  +   +   + +E+      L+ +++ H+NDS    GSRKDRH +IG G++G    V+  ++   A  P +LETP  D
  S:     3 LFGAHM--SAAGGVSNAIRDIVEIGGEVLQLFTANQRQWTPKAPSE----ADVEAFGRRRAAFGGPVFSHASYLINIANGDGAASAKAVEALVREFERCTALGVDAVVLHPGAHLGAGRGTGILRAARNIDEVFDRCGGQTPVLLLENTAGQGTCLGGDLNDLAEIIDASRHASQLGVCLDTAHAFGAGYALHTDEGYRRCMEDIEHGPGLAAVRLFHVNDSLVPCGSRKDRHTHIGEGQLGEAAFVRLLNDPVFAMHPMVLETPKED 264
>gi|167044685|gb|ABZ09356.1| putative AP endonuclease family 2 [uncultured marine microorganism HF4000_APKG7H23] (285 aa)
Score = 269, Expect = 7.6e-22, Identities = 72/260 (27%), Positives = 126/260 (48%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENI---VVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQ---TLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           LG+HV   A   +  ++   +E       +F    Q +  K LD+       +    K   L  +I   V+H  YL+ LG+ +      G+  L+  +N  + +    +V H GS   +        + +++N+ ++ + +D ++ +E  AG G+ +G  F E+  ++  V    R+ VCLDT H   +G D++ P+    TL +F   + L ++  IH NDSK ++G+  DRH+NIG G +G +          L +VP  LE P
  S:     3 LGAHV--SAAGGIDLAIDRGVEIGAEAVQIFASSNQQWAFKPLDEK------QTASFKTKALEHSIGPNVLHGIYLVTLGTEEPELLRRGVQSLVNYMNAAHDLGMLGVVFHLGSHKGAGFEAVFRQVVESMNRVLDNSPDDTLLIMENSAGMGNHIGSKFHELGTLLKEV-GSPRVKVCLDTQHSFAAGYDLTTPEAVAGTLRQFDGEIGLEHLAAIHCNDSKRDLGAGVDRHENIGEGYMGLEAFEAILAAPALRDVPFYLEVP 259
>gi|95931183|ref|ZP_01313905.1| apurinic endonuclease (APN1) [Desulfuromonas acetoxidans DSM 684] >gi|95132745|gb|EAT14422.1| apurinic endonuclease (APN1) [Desulfuromonas acetoxidans DSM 684] (229 aa)
Score = 268, Expect = 8.5e-22, Identities = 59/163 (36%), Positives = 92/163 (56%)
  Q:    93 ENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKD 255
           E I+ H  YLINLG P+           I E+ R   +    +  HPGS L + D    +  IA+++N A+E T + V+  +E  AG+GS VG  FE +++I+  V ++ R+GVCLDTCH+  +G D+      D+T  +F++ +    +  +HLNDSK  +G   D
  S:    64 EQILPHDSYLINLGHPQADKLEKSRQAFIDEMQRCEALGLTRLNFHPGSHLREIDERACLARIAESINLALEQT-HSVVAVIENTAGQGSNVGYCFEHLAEILCQVADQSRVGVCLDTCHLFAAGYDLRTAAACDETFGQFAEQVGFERLYGMHLNDSKTALGKHVD 229
>gi|48478138|ref|YP_023844.1| endonuclease IV [Picrophilus torridus DSM 9790] >gi|48430786|gb|AAT43651.1| endonuclease IV [Picrophilus torridus DSM 9790] (273 aa)
Score = 265, Expect = 2.0e-21, Identities = 79/237 (33%), Positives = 117/237 (49%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG 266
           LG+H+        V  +  ++ +  N F +F    +++  KE      DE            +E  V HA YLINL S  E  R   +N L  EI   N +    +V+HPGS  + DR   I    D   +++E     ++I  E  +G+G+    +  E+S I+  + +KK  G+CLDTCH +  G D+   D  +    K L+LS I VIHLNDSK E  S+KD H+N G G++G
  S:     8 LGAHISIGNGIENVPEIAHSMNF--NAFQIFV-KSRSWQEKEYK---YDEIANFRNNVRKFNIEGTVAHAIYLINLASENE-IRKKSINDLNNEIKICNDLGIDYLVVHPGS--NPDRKKGIKMAIDAF-QSMETGSTKILI--ENSSGRGNTFPSDINEMSGIIDSL-DKKHFGLCLDTCHAYSYGYDLCKYDDFIYYMGKKLELSRINVIHLNDSKTEFASKKDLHENPGSGRIG 231
>gi|115803102|ref|XP_797345.2| PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] >gi|115939259|ref|XP_001180635.1| PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] (479 aa)
Score = 264, Expect = 2.6e-21, Identities = 58/153 (37%), Positives = 89/153 (58%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSK 247
           I+ H  YL+N GSP  +T S   + L+ E++R  ++   L   HPGS   D      ++ I +++N A+  T   V   +E M+ +G  +G +FEE+  I+  VK+K RIGVCLDTCH   +G D+S      + + EF + +   Y+K +HLNDSK
  S:   318 ILPHGSYLLNCGSPNPATLSKSRDSLVDELSRCQKLGLTLYNFHPGSTCGDITIEECLDKIGESINMALAKTSG-VTAVIENMSRQGHTIGGDFEELRGIIDRVKDKSRIGVCLDTCHAFAAGYDLSTESGYKKMMAEFERVIGFQYLKGVHLNDSK 473
>gi|119717314|ref|YP_924279.1| endonuclease IV [Nocardioides sp. JS614] >gi|119537975|gb|ABL82592.1| Endonuclease IV [Nocardioides sp. JS614] (294 aa)
Score = 264, Expect = 2.7e-21, Identities = 77/270 (28%), Positives = 133/270 (49%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIE---------ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDL---SYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP-YRD----DKPIYKQ 299
           +G+HV    K  + G+V          F VFTG P+ +   E           LM  +       + +HAPYL+NLGSP  +T    +  +   + R  +I ++ +V+H GS +D     ++   A  + +  E         A D+   + +E  AG+G  +    E+++  +  + +  + G+CLDTCH+  +G  + +P  T     + +++     ++++H NDS +  G+ KDRH  IG G +G     +   +     VP ILETP  RD    D P+ K+
  S:    10 IGTHV-LVGKGLVDGAVANADLVACETFQVFTGNPRGWALSEGKPADDARFRDLMAARG----TRVFIHAPYLVNLGSPTPATYERSVASVAHNLKRAAEIGAEGVVVHTGSYVDPGEGDSLARHARAMRQVREGLLPLLDAVAGDDAPWLLLEPTAGQGRSLCAGVEDLAPYLEALDHHPKAGICLDTCHVFAAGAPLDEPGGTTATVDRVVEIGGPGRLRLVHANDSMDVRGAFKDRHQRIGEGHIGEGAFTELFAHPATEGVPFILETPDSRDVDNRDIPLLKK 291
>gi|169869098|ref|XP_001841117.1| hypothetical protein CC1G_08261 [Coprinopsis cinerea okayama7#130] >gi|116497759|gb|EAU80654.1| hypothetical protein CC1G_08261 [Coprinopsis cinerea okayama7#130] (467 aa)
Score = 262, Expect = 3.9e-21, Identities = 51/130 (39%), Positives = 86/130 (66%)
  Q:   176 MAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVG---FDYLVKWAHNEKLANVPKILETP-YRDDKPIYKQEIINLN 305
           +AG G+ +G  FE++ +I+  V++K R+GVC+DTCH   +G DI   +   +T+++F + + L Y+K +HLNDSK    S+KDRH+NIG G +G   F Y++    + +   +P +LETP +   + ++  E+  LN
  S:   198 VAGTGNIIGATFEQLKEIIDQVEDKTRVGVCIDTCHAFSAGYDIRTKEGWNETMDKFERVIGLEYLKGMHLNDSKTAFDSKKDRHENIGLGTIGLASFSYILA---DPRTRGIPMVLETPSFEKPREVWGVEVEVLN 331
>gi|145595769|ref|YP_001160066.1| apurinic endonuclease Apn1 [Salinispora tropica CNB-440] >gi|145305106|gb|ABP55688.1| Endonuclease IV [Salinispora tropica CNB-440] (286 aa)
Score = 262, Expect = 4.0e-21, Identities = 62/195 (31%), Positives = 102/195 (52%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSD-RNVAINHIADNLNKAIEAT--DNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDIS---DPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           + +HA  L+NLGSP  +T       L   + R   I ++ +V H GSA+D+   + A+  + D L   ++ T   N  ++ VE  AG G  +    E++   +  V     +GVC DTCH   +G D++       TL+     +    ++++H NDSK+  GS +DRH+NIG G +G     +  ++   A VP ++ETP
  S:    67 VFIHASLLVNLGSPTAATVERSALTLAHALRRGTAIGAQGVVFHAGSAVDAGYADTAMRQVRDVLLPLLDTTGDTNGPMLLVEPSAGGGRSLAARVEQLGPYLDAVDRHPWLGVCFDTCHAWAAGHDLAVEGGMTATLDTLVNTVGADRLRLVHANDSKDLCGSTRDRHENIGKGAIGEPAFAELMYHPATAGVPTVVETP 267
>gi|120602878|ref|YP_967278.1| apurinic endonuclease Apn1 [Desulfovibrio vulgaris subsp. vulgaris DP4] >gi|166224278|sp|A1VEI5|END4_DESVV Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|120563107|gb|ABM28851.1| Endonuclease IV [Desulfovibrio vulgaris subsp. vulgaris DP4] (282 aa)
Score = 262, Expect = 4.0e-21, Identities = 68/264 (25%), Positives = 128/264 (48%)
  Q:    29 LLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDV-IICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRD 292
           L G+H+   A   +  ++ + +E  G    +FT   + +  K          V+  + +       +  HA YLIN+ +   +  +  +  L+ E  R   +    +VLHPG+ L + R   I   A N+++  +        + +E  AG+G+ +G    ++++I+   ++  ++GVCLDT H   +G  +   +   + +E+      L+ +++ H+NDS    GSRKDRH +IG G++G    V+  ++   A  P +LETP  D
  S:     3 LFGAHM--SAAGGVSNAIRDIVEIGGEVLQLFTANQRQWTPKAPSA----ADVEAFRRRRAAFGGPVFSHASYLINIANGDGAASAKAVEALVREFERCTALGVDAVVLHPGAHLGAGRGAGILRAARNIDEVFDRCGGQTPALLLENTAGQGTCLGGGLNDLAEIIDASRHASQLGVCLDTAHAFGAGYALHTDEGYRRCMEDIEYGPGLAAVRLFHVNDSLVPCGSRKDRHTHIGEGQLGEAAFVRLLNDPVFAMHPMVLETPKED 264
>gi|78357445|ref|YP_388894.1| endonuclease IV [Desulfovibrio desulfuricans subsp. desulfuricans str. G20] >gi|78219850|gb|ABB39199.1| Endonuclease IV [Desulfovibrio desulfuricans G20] (294 aa)
Score = 260, Expect = 7.6e-21, Identities = 63/192 (32%), Positives = 110/192 (57%)
  Q:    98 HAPYLINLG--SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND-VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           HA YLIN    +P+ + RS+ L  +  E+ R  ++  +++V+HPG+             A  L++A+E   +  V++ +E  AG+G+ +G +F  ++ ++   +  +R G+CLDT H   +G D+ D    D  + E      L  ++++H NDS   +GSR+DRH +IG G++G         +E+L +VPK+LETP
  S:    78 HASYLINPAADTPEGAERSVAL--MADELQRAGRLGIEMVVVHPGAHKGQGEAAGAALAAARLDEALERCGSPAVMVLLENTAGQGTMLGASFAGLAAVIEASRMPERYGICLDTAHAFGAGYDLRDAALYDAAIRELDVCAGLDRLRLVHANDSLTGLGSRRDRHTHIGQGELGEAAFRLLMRDERLHHVPKVLETP 273
>gi|55819174|ref|YP_142650.1| endonuclease IV [Acanthamoeba polyphaga mimivirus] >gi|77416695|sp|Q5UPY4|END4_MIMIV Putative endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|55416918|gb|AAV50568.1| endonuclease IV [Acanthamoeba polyphaga mimivirus] (312 aa)
Score = 259, Expect = 1.1e-20, Identities = 79/245 (32%), Positives = 135/245 (55%)
  Q:    57 FMVFTGPPQNFMRKELDQNLIDEAVKLMKE--KNPLLLENIVVHAPYLINLGSPKESTR-SLGLNQLIVEINRTNQIHSKL--IVLHPGSALDSDR---NVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKN--KKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           F +F G PQ  + K   +   DE ++  K+  K+ L++   VVH  Y INL  P  S +    +  L+ ++N TN I  +   +++H G  +  ++   + AI++    +  A+  T ++  I +ET A +GSEV  + + +++I   + +  ++R+  C+DTCH+  +G DIS P    +  +EF K + +  I  IH NDSK  + S+ DRH ++ YG++G + L   A   K   +  I+ETP     P   QEI
  S:    47 FQIFLGAPQQILSKARQK---DELIEFGKQLIKHDLIM---VVHGSYTINLCHPPGSKKFETSIKSLVKDLNATNLIGDRCLGVIIHMGKNISENKLTVDQAIDNYVTGIKTALSQTPDNTTIVLETGASQGSEVASHIDGLAQIYWCLNDAERERVYFCIDTCHIWATGYDISSPTGVKKFFKEFDKKIGVEKISCIHFNDSKTGLESKVDRHADLCYGEIGSNGLKAIAKFAKEYKIHLIMETPLDAINPETNQEI 298
>gi|47205664|emb|CAF92394.1| unnamed protein product [Tetraodon nigroviridis] (138 aa)
Score = 259, Expect = 1.1e-20, Identities = 49/116 (42%), Positives = 73/116 (62%)
  Q:   176 MAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYR 291
           M G+G+ VG  F E+  I+  V+++ R+GVCLDTCH   +G D++        L+EF + + L Y+K +HLNDSK ++G   DRH++IG G +G        +  +L N+P ILETP R
  S:     1 MCGQGATVGGRFSELRGIIDKVRDQSRVGVCLDTCHAFAAGYDLAAEGGVRAMLDEFDQEVGLHYLKAVHLNDSKGQLGCNLDRHEDIGKGCIGISAFRDVVNEPRLNNIPLILETPGR 119
>gi|170582065|ref|XP_001895961.1| DNA-(Apurinic or apyrimidinic site) lyase [Brugia malayi] >gi|158596936|gb|EDP35195.1| DNA-(Apurinic or apyrimidinic site) lyase, putative [Brugia malayi] (371 aa)
Score = 255, Expect = 3.0e-20, Identities = 56/125 (44%), Positives = 79/125 (63%)
  Q:   187 FEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEII----NLNSKEWKE 311
           FEE+ +I++ VKNKKR+GVC DTCH+  +G DI   D   +T  EF   + L Y++  H+NDS  ++GS+ DRH NIG GK+          +++   +P ILETP  D    Y +E+I    +LNSK  KE
  S:   232 FEELQQIINLVKNKKRVGVCFDTCHIFAAGYDIRSEDRYKETFSEFENTIGLQYLRAFHINDSMGDLGSKLDRHANIGKGKLKLAAFRNLIADQRFDGLPMILETPEGD----YAEEMIRLYHSLNSKPLKE 359
>gi|162456294|ref|YP_001618661.1| hypothetical protein sce8011 [Sorangium cellulosum 'So ce 56'] >gi|161166876|emb|CAN98181.1| nfo [Sorangium cellulosum 'So ce 56'] (323 aa)
Score = 255, Expect = 3.1e-20, Identities = 62/213 (29%), Positives = 114/213 (53%)
  Q:    96 VVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLN------KAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNK-KRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILE-TPYRDDKPIYKQEIINLNSKE 308
           + HA YLINL +   +        L  E+ R + +    +V HPG+         ++ I ++L+      K + A      +C+E  AG+GS +G   ++++ ++     +  R+GVC+DT H   +G D+      ++   +F + L L  ++ +H+NDSK  +G R DRH+ +G G++G     + A++ +LA VP ++E  P   ++  Y +EI  L + E
  S:    72 LAHASYLINLCADDAAILERSREALFQELARCDALGIDFVVFHPGAHRSLGEEAGLDRIGESLSIVLSRGKGLRAR-----LCIENTAGQGSTLGDRVDQIAAMIERAGPEGSRLGVCIDTQHAFAAGHDLRSEAGYERFWSDFGRLLGLHRLQCMHVNDSKAALGQRVDRHERVGDGEMGLAPFWRLANDARLARVPAVIELPPLSKERRGYLEEIARLRALE 290
>gi|55980803|ref|YP_144100.1| endonuclease IV [Thermus thermophilus HB8] >gi|55772216|dbj|BAD70657.1| endonuclease IV [Thermus thermophilus HB8] (270 aa)
Score = 252, Expect = 6.5e-20, Identities = 76/259 (29%), Positives = 130/259 (50%)
  Q:    31 GSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIE--ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDIS-DPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           G H+    K  + G+V E        F +F   P+++  + L    + EA + ++E +  L    V+HA YL+NLG+  E      +  L  ++ +   +  + +V+HPGS            + +   KA+      +  ++ VE  AG G +VG  FEE++ +V+       + VCLDTCH + +G D++ DP   L+   + + L  + V+HLNDS   +GSR D H ++  GK+G + L +   + +L +   ILETP
  S:     5 GFHLSIAGKKGVAGAVEEATALGLTAFQIFAKSPRSWRPRALSPAEV-EAFRALREASGGL--PAVIHASYLVNLGAEGELWEK-SVASLADDLEKAALLGVEYVVVHPGSGRPE-------RVKEGALKALRLAGVRSRPVLLVENTAGGGEKVGARFEELAWLVADTP----LQVCLDTCHAYAAGYDVAEDPLGVLDALDRAVGLERVPVVHLNDSVGGLGSRVDHHAHLLQGKIG-EGLKRVFLDPRLKDRVFILETP 250
>gi|46198790|ref|YP_004457.1| endonuclease IV [Thermus thermophilus HB27] >gi|59797793|sp|Q72KH8|END4_THET2 Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|46196413|gb|AAS80830.1| endonuclease IV [Thermus thermophilus HB27] (270 aa)
Score = 252, Expect = 6.5e-20, Identities = 76/259 (29%), Positives = 130/259 (50%)
  Q:    31 GSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIE--ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDIS-DPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           G H+    K  + G+V E        F +F   P+++  + L    + EA + ++E +  L    V+HA YL+NLG+  E      +  L  ++ +   +  + +V+HPGS            + +   KA+      +  ++ VE  AG G +VG  FEE++ +V+       + VCLDTCH + +G D++ DP   L+   + + L  + V+HLNDS   +GSR D H ++  GK+G + L +   + +L +   ILETP
  S:     5 GFHLSIAGKKGVAGAVEEATALGLTAFQIFAKSPRSWRPRALSPAEV-EAFRALREASGGL--PAVIHASYLVNLGAEGELWEK-SVASLADDLEKAALLGVEYVVVHPGSGRPE-------RVKEGALKALRLAGVRSRPVLLVENTAGGGEKVGARFEELAWLVADTP----LQVCLDTCHAYAAGYDVAEDPLGVLDALDRAVGLERVPVVHLNDSVGGLGSRVDHHAHLLQGKIG-EGLKRVFLDPRLKDRVFILETP 250
>gi|124515846|gb|EAY57355.1| Endonuclease IV [Leptospirillum sp. Group II UBA] (317 aa)
Score = 250, Expect = 9.9e-20, Identities = 59/199 (29%), Positives = 101/199 (50%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIE-ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSY---IKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDD 293
           +++HA YL+N  +     R      L  +    N++    +VLHPGSA       AI   A+ +   ++       ++ +E  AG G  +G +   + ++V  V   +++G+CLD+CH+  SG +I +P    E  S + + +    I+  HLND+  E GS +DRH +IG G +G  +      + +   +P +LETP  DD
  S:    77 VLMHASYLVNTATSDPEKRKKSAAALEEDWILANRLGVYGLVLHPGSAAGQSDAAAIRLSAEMIRDTVDREKGGSTLLLLENTAGGGRTLGRDPGTMKQLVDRVDRPEKVGLCLDSCHLLASGAEIRNPRSYEEVLSAWTEAAGPGGIRAWHLNDALFERGSGRDRHAHIGKGSIGLWFFWTLLRDHRFTGIPMVLETPKTDD 279
>gi|70941694|ref|XP_741103.1| hypothetical protein PC102725.00.0 [Plasmodium chabaudi chabaudi] >gi|56519270|emb|CAH76630.1| hypothetical protein PC102725.00.0 [Plasmodium chabaudi] (474 aa)
Score = 249, Expect = 1.5e-19, Identities = 61/153 (39%), Positives = 87/153 (56%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSK 247
           I+ H  YLINL +P +  R       + +I R  Q++ KL   HPGS +        I +IAD +N+A + T N VII +E  AG+ + VG  FE +  I+S V +K+RIGVCLDTCH   +G DI      ++ +  F   +D  Y+K +HLN  K
  S:   319 ILPHGSYLINLANPDKEKREKSYLSFVDDIKRCEQLNIKLYNFHPGSTVGMCSTEQGIKNIADCINRAHKETSN-VIIVLENSAGQKNSVGSKFEHLRDIISQVDDKERIGVCLDTCHTFAAGYDIKTYEKFEEVMNNFHNIVDSKYLKAVHLNAFK 474
>gi|8809789|gb|AAF79945.1|AF233851_3 putative endonuclease IV [Streptomyces toyocaensis] (253 aa)
Score = 249, Expect = 1.6e-19, Identities = 60/172 (34%), Positives = 95/172 (55%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIE--ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFD 268
           VHAPYLIN GS   +T    +  L   + R  +I +  +V+H GSA    +R+VA+  +   +   ++    D+D  + +E+ AG+GS +     +       +    ++GVCLDTCH+  +G D++ PD   QT       +    +K+IH NDS + +G+ KDRH NIG G +G D
  S:    75 VHAPYLINFGSHTLATVERSVESLRHSLRRGREIGALGVVVHTGSATGGRERSVALRQVRRYMLPLLDELTHDDDPFLLLESTAGQGSSLCSRTWDFGPYFEALDAHPKLGVCLDTCHVFAAGHDLTGPDGMRQTAGLLVDTVGEGRLKLIHANDSMDVVGAHKDRHANIGAGHIGED 252
>gi|159039021|ref|YP_001538274.1| apurinic endonuclease Apn1 [Salinispora arenicola CNS-205] >gi|157917856|gb|ABV99283.1| apurinic endonuclease Apn1 [Salinispora arenicola CNS-205] (287 aa)
Score = 247, Expect = 2.1e-19, Identities = 60/195 (30%), Positives = 101/195 (51%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSD-RNVAINHIADNLNKAIEATDN--DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDIS---DPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           + +HA  L+NLGSP  +T       L   + R   I ++ +V H GSA+D+   + A+  + + L   ++ T +    ++ VE  AG G  +    E++   +  V     +GVC DTCH   +G D++       TL+     +    ++++H NDSK+  GS +DRH+NIG G +G     +   +   A VP ++ETP
  S:    68 VFIHASLLVNLGSPTAATVERSALTLAHALRRGTAIGAQAVVFHAGSAVDAGYADAAMRQVREVLLPLLDTTGDAGGPMLLVEPSAGGGRSLAARVEQLGPYLDAVDRHPWLGVCFDTCHAWAAGHDLAVEGGMTATLDTLVTTVGADRLRLVHANDSKDLRGSTRDRHENIGKGAIGEPAFAELMRHPATAGVPVLVETP 268
>gi|116625054|ref|YP_827210.1| endonuclease IV [Solibacter usitatus Ellin6076] >gi|116228216|gb|ABJ86925.1| Endonuclease IV [Solibacter usitatus Ellin6076] (290 aa)
Score = 244, Expect = 5.1e-19, Identities = 77/239 (32%), Positives = 113/239 (47%)
  Q:    57 FMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEA-TDNDVIICVETMAGKGSEVGINFEEVSKI--VSGVKNKKRIGVCLDTCHMHDSGIDI-SDPD--QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKP 295
           F +F+  P+ +  +  D   I     L   +    L  +V+H  YL+NL S     R+  ++    E+ R   I ++ +V+HPGS         I   A  L  A      + + + +E  AG G  +G  FEE+  I  ++       IG CLDTCH+  +G DI + P    TL      L L+ + V H NDS+   GS  DRH +IG G +G D   +   + KL   P ILETP   D+P
  S:    28 FQIFSASPRMWRARVPDPVQIK---LLCAARERFSLSPLVIHTNYLVNLASLDPVIRAKSIDAFRGELQRAIAIGAEYLVVHPGSYRGHTVEEGIAAFALGLRDASAGLPPHQLTVLLENTAGAGCHLGGKFEELRSIRDLTAELTDLPIGYCLDTCHLLAAGFDIVTAPGLRATLRAAEAVLGLANVHVFHANDSRFPRGSHVDRHAHIGEGFIGADAFRRILTHPKLRRKPFILETPV--DEP 267
>gi|67526979|ref|XP_661551.1| hypothetical protein AN3947.2 [Aspergillus nidulans FGSC A4] >gi|40740066|gb|EAA59256.1| hypothetical protein AN3947.2 [Aspergillus nidulans FGSC A4] (512 aa)
Score = 242, Expect = 9.1e-19, Identities = 55/151 (36%), Positives = 85/151 (56%)
  Q:   139 PGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNK--KRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           PGS   +  + A+  +A  L  A+ AT N V+  +ETM G GS +G +  E   +++ +  +   RIGVC+DTCH   +G D+  P      L+EF   + + +++ +HLNDSK   GS++D H NIG G +G        +  +   +P ILETP
  S:   210 PGSTNKTPLSSALARLAKALTNALAATSN-VVPVLETMCGHGSTIGGSLSEFRDLLALIPKEYHSRIGVCIDTCHSFAAGYDLVSPAGFQAFLKEFEDLIGIQHLRALHLNDSKAPGGSKRDLHANIGTGFLGLRAFHNVMNEPRFEGLPMILETP 364
>gi|145243344|ref|XP_001394205.1| hypothetical protein An11g02010 [Aspergillus niger] >gi|134078877|emb|CAK40563.1| unnamed protein product [Aspergillus niger] (436 aa)
Score = 240, Expect = 1.6e-18, Identities = 68/242 (28%), Positives = 114/242 (47%)
  Q:    54 GNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVL---------HPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNK--KRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKP 295
           GN F +F    + +    L  +  D+   L  E      ++I+ H  YL+NL    ++      +  + ++ R   +   L            HP +  +   + +          +  A  + V   +ETM G GS +G    E   I+S +  +   RIG+C+DTCH   +G D++ P      ++EFS  + + Y++ +HLNDSK   GS++D H NIG G +G        +  +   +P ILETP   D+P
  S:    38 GNAFALFLKSQRKWDNPALQDDHRDQFRNLCIEHKYDGAKHILPHGSYLVNLAQEDKAKAKQAYDAFLDDLRRCEALGITLYNFQYIPLPYTPHPTNPANQTSHASAITRLAAALTSALAATSTVTPVLETMCGHGSTIGGYLHEFRDILSQIPKEYHHRIGICIDTCHSFAAGYDLASPSGFASFMQEFSDVIGIQYLRALHLNDSKAPRGSKRDLHANIGTGFLGLRAFHNVMNEPRFQGLPMILETPI--DRP 291
>gi|124485053|ref|YP_001029669.1| endonuclease IV [Methanocorpusculum labreanum Z] >gi|166224284|sp|A2SPZ6|END4_METLZ Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|124362594|gb|ABN06402.1| Endonuclease IV [Methanocorpusculum labreanum Z] (281 aa)
Score = 237, Expect = 3.6e-18, Identities = 73/265 (27%), Positives = 131/265 (49%)
  Q:    30 LGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSD-RNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD-QTLEEFSKYLD----LSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP---YRDDK 294
           LG HV       L  +V    E   + F +FT  P+ +  K ++ ++ +  +  +   N   +  +V H PYL N  + K    +  +  +  E++R +Q+    +V H G     D        +   + +A++ ++ + +I +E  A + + VG  F ++  I   + N++R+G C DTCH   +G D+     +T+  F  + D    L  +KVIHLND K  +GS  DRH+++G G +G + +       K+++   I+ETP    R DK
  S:     4 LGFHVSIAGS--LPLAVSRAQEAGCDTFQIFTRSPRVWAAKPIEPSIAEAFIDAL---NISGIGPVVDHMPYLPNPAAEKPEIYARSIFTMTEELDRCDQLKIPYLVTHLGHHGKEDGHKKGQEKVIAAIGQALDESEGETMILLENTANEKNTVGGTFTDIGVISDALSNERRVGFCFDTCHAAAAGYDLKGHGAETV--FGWFNDEAGSLDRLKVIHLNDMKGGVGSHLDRHEHLGLGYLGEETIHDVLTFPKISHCAFIMETPSDEIRTDK 270
>gi|149240533|ref|XP_001526142.1| DNA-(apurinic or apyrimidinic site) lyase 1 [Lodderomyces elongisporus NRRL YB-4239] >gi|146450265|gb|EDK44521.1| DNA-(apurinic or apyrimidinic site) lyase 1 [Lodderomyces elongisporus NRRL YB-4239] (214 aa)
Score = 236, Expect = 5.0e-18, Identities = 52/136 (38%), Positives = 82/136 (60%)
  Q:   176 MAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKP--IYKQEIINLNSKEWKE 311
           MAG G+ +G N +++  ++  +++K R+GVCLDTCH   +G DI D    +  L+ F   +   Y+  IHLNDSK  +G+ +D H  +G G +G +     A+ ++L N+P +LETP   ++   IY +EI  L   EW E
  S:     1 MAGHGNLIGSNLQDIKDVIDMIEDKSRVGVCLDTCHSFAAGYDILDATKLEDFLQNFDDLIGAEYLSAIHLNDSKAPLGANRDLHQKLGQGFLGLEVFRAIANCKRLQNIPIVLETPIEKNETDEIYGEEIKLL---EWLE 138
>gi|196234987|ref|ZP_03133791.1| apurinic endonuclease Apn1 [Thermus aquaticus Y51MC23] >gi|196220943|gb|EDY15558.1| apurinic endonuclease Apn1 [Thermus aquaticus Y51MC23] (276 aa)
Score = 230, Expect = 2.3e-17, Identities = 74/272 (27%), Positives = 130/272 (47%)
  Q:    31 GSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIE--ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDI-SDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEII 302
           G H+    K  + G++ E +      F +F   P+++  + L  N + EA + +KE    +    V+HA YL+NLG+  E      +  L  ++ +   +  + +V+HPGS  D  R      + +   KA+          + +E  AG G +VG  FEE++ ++        +  CLDTCH   +G D+  DP   L    K + L  + V+HLNDS    GSR D+H ++  G++G + L     + +L     +LETP   ++  +  +++
  S:     5 GFHLSIAGKKGVAGALEEAMALGLTAFQIFAKSPRSWRTRPLAANEV-EAFRALKEMAGGM--PAVIHASYLVNLGAEGELWEK-SVMSLADDLEKAAILGVEYVVVHPGSG-DPKR------VKEGALKALRLAGVRGKPTLLLENTAGGGEKVGSRFEELAWLLEDTP----LQACLDTCHAFAAGYDVKEDPKGVLTALDKAVGLERVPVVHLNDSVGGFGSRIDQHAHLLQGQIG-EGLKGVLLDPRLRGRVFVLETPRSPEEDAWNLKVL 263
>gi|163785871|ref|ZP_02180333.1| deoxyribonuclease IV [Hydrogenivirga sp. 128-5-R1-1] >gi|159878859|gb|EDP72901.1| deoxyribonuclease IV [Hydrogenivirga sp. 128-5-R1-1] (156 aa)
Score = 223, Expect = 1.4e-16, Identities = 50/128 (39%), Positives = 75/128 (58%)
  Q:   173 VETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDP---DQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQE 300
           VET+AG+  E+G   +E+  ++   +++  IGVCLDTCH++ +G  I+         +EF   + L  IKVIH NDSK    SRKDRH++IG G +G      + ++E    +P ILETP + +  I   E
  S:    11 VETLAGQKGEIGKTTQEIKALIQPFESEN-IGVCLDTCHIYSAGYKINKEKGFQDYKDEFDTLIGLDKIKVIHCNDSKTPFNSRKDRHEHIGKGSIGLKGFEFFLNDEYFCRLPFILETPKQGNMDIVNME 140
>gi|76664852|emb|CAJ17863.1| endonuclease IV [Candidatus Phytoplasma solani] (119 aa)
Score = 223, Expect = 1.5e-16, Identities = 45/108 (41%), Positives = 66/108 (61%)
  Q:   202 RIGVCLDTCHMHDSGIDISDPDQTL-EEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEW 309
           RI  CL TCH+ D+G D+ +   +  E+    L +  I  IH+NDSKN   S KDRH+NIG+G++GF  L +  ++     +PKILETPY + +  Y +EI  + SK +
  S:     2 RISFCLHTCHLFDAGYDLKNNLMSFWEDVESILGIENISAIHINDSKNTCKSHKDRHENIGFGQIGFKVLSQIIYHPAFLQIPKILETPYINGQAPYLEEIKMIKSKRF 110
>gi|118466381|ref|YP_883635.1| endonuclease IV [Mycobacterium avium 104] >gi|118167668|gb|ABK68565.1| endonuclease IV [Mycobacterium avium 104] (325 aa)
Score = 222, Expect = 1.7e-16, Identities = 76/261 (29%), Positives = 119/261 (45%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDG-NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILET 288
           +L+GSHV    +N      L   + DG +    F   PQ++ + +      D+A  L     PL      VHAPYLIN+ S     R      L    +   +I++  +++H G A D+D             KA++  + DV + +E  AG    +  +F+ + ++   + +K  IG CLDTCH   +G  + D    ++  +  +DL     +H NDS++  GS  DRH N G G++  D LV      K A  P I ET
  S:    75 VLIGSHV----RN---DDPLAAAQADGADVVQFFLSNPQSWKKPQPR----DDAEALKASSVPLY-----VHAPYLINVASANNRVRIPSRKILQDTCDAAAEINATAVIVHGGHADDNDMEAGFERWV----KALDYLETDVQVYLENTAGGDHAMARHFDTIGRLWDRIGDKG-IGFCLDTCHAWAAGEALIDAVDRIKALTGRIDL-----VHCNDSRDAAGSGADRHANFGTGQIDPDLLVTVV---KAAAAPVICET 307
>gi|118468437|ref|YP_885769.1| endonuclease IV [Mycobacterium smegmatis str. MC2 155] >gi|118169724|gb|ABK70620.1| endonuclease IV [Mycobacterium smegmatis str. MC2 155] (250 aa)
Score = 222, Expect = 2.2e-16, Identities = 68/229 (29%), Positives = 108/229 (47%)
  Q:    60 FTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILET 288
           F G PQ++ + +  +    +A  L     PL      VHAPYLIN+ S     R      L    +   +I +  +++H G A D+D             KA++A D DV + +E  AG    +  +F+ ++++   + +K  IG CLDTCH   +G  + D  + ++  +  +DL     +H NDS++  GS  DRH N G G++    L   A   K A+ P I ET
  S:    27 FLGNPQSWKKPKPRE----DAEVLKASTIPLY-----VHAPYLINVASANNRVRIPSRKILQDTCDAAAEIGATAVIVHGGHADDNDMEAGFTRWV----KALDALDTDVPVYLENTAGGDHAMARHFDTIARLWDHIGDKG-IGFCLDTCHAWAAGEALIDAVERIKSITGRIDL-----VHCNDSRDAAGSGADRHANFGAGQIDPQLL---AAVVKAADAPVICET 233
>gi|41410230|ref|NP_963066.1| endonuclease IV [Mycobacterium avium subsp. paratuberculosis K-10] >gi|41399064|gb|AAS06682.1| End [Mycobacterium avium subsp. paratuberculosis K-10] (251 aa)
Score = 218, Expect = 6.3e-16, Identities = 64/211 (30%), Positives = 98/211 (46%)
  Q:    78 DEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILET 288
           D+A  L     PL      VHAPYLIN+ S     R      L    +   +I++  +++H G A D+D             KA++  + DV + +E  AG    +  +F+ + ++   + +K  IG CLDTCH   +G  + D    ++  +  +DL     +H NDS++  GS  DRH N G G++  D LV      K A  P I ET
  S:    41 DDAEALKASSVPLY-----VHAPYLINVASANNRVRIPSRKILQDTCDAAAEINATAVIVHGGHADDNDMEAGFERWV----KALDYLETDVQVYLENTAGGDHAMARHFDTIGRLWDRIGDKG-IGFCLDTCHAWAAGEALIDAVDRIKALTGRIDL-----VHCNDSRDAAGSGADRHANFGTGQIDPDLLVTVV---KAAAAPVICET 233
>gi|119718883|ref|YP_925848.1| endonuclease IV [Nocardioides sp. JS614] >gi|119539544|gb|ABL84161.1| Endonuclease IV [Nocardioides sp. JS614] (269 aa)
Score = 216, Expect = 8.6e-16, Identities = 65/230 (28%), Positives = 103/230 (44%)
  Q:    60 FTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSA-LDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKI---VSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           F G PQ +   E       EA+K   E   +    + VHAPY++N+ +     R      L   ++    I ++ +++H G    D D         DN  KAIEA D  + + +E  AG  + +    E + ++   +S  +    +G CLDTCH H  G  +      +   +  +DL     +H NDS++   S  DRH ++G G+V  D L     +   A  P +LETP
  S:    33 FLGDPQGYQGPEFRYAGGAEALKADAEAAGV---GLYVHAPYIVNVATTNNRIRIPSRKLLQQHVDAAASIGARGLIVHGGHVNKDDDPEKGF----DNWRKAIEAVDLKLPLLIENTAGGDNAMTRYLERIGRVWDAISSAEQADLVGFCLDTCHAHAGGNSLETVVDDVRRITGRIDL-----VHCNDSRDAFDSGADRHASLGAGQVDPDLLAAVVRD---AGAPVVLETP 251
>gi|15607810|ref|NP_215184.1| endonuclease IV [Mycobacterium tuberculosis H37Rv] >gi|15840073|ref|NP_335110.1| endonuclease IV [Mycobacterium tuberculosis CDC1551] >gi|31791854|ref|NP_854347.1| endonuclease IV [Mycobacterium bovis AF2122/97] >gi|121636591|ref|YP_976814.1| endonuclease IV [Mycobacterium bovis BCG str. Pasteur 1173P2] >gi|148660445|ref|YP_001281968.1| endonuclease IV [Mycobacterium tuberculosis H37Ra] >gi|148821875|ref|YP_001286629.1| endonuclease IV [Mycobacterium tuberculosis F11] >gi|167967572|ref|ZP_02549849.1| endonuclease IV [Mycobacterium tuberculosis H37Ra] >gi|194543047|ref|YP_002078076.1| endonuclease IV end (endodeoxyribonuclease IV) (apurinase) [Mycobacterium tuberculosis C] >gi|166224286|sp|A1KGF0|END4_MYCBP Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|166224287|sp|A5U056|END4_MYCTA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|54037046|sp|P63536|END4_MYCBO Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|54040806|sp|P63535|END4_MYCTU Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|3261531|emb|CAA17467.1| PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) [Mycobacterium tuberculosis H37Rv] >gi|13880221|gb|AAK44924.1| AP endonuclease, family 2 [Mycobacterium tuberculosis CDC1551] >gi|31617441|emb|CAD93551.1| PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) [Mycobacterium bovis AF2122/97] >gi|121492238|emb|CAL70705.1| Probable endonuclease IV end [Mycobacterium bovis BCG str. Pasteur 1173P2] >gi|124600054|gb|EAY59064.1| endonuclease IV end (endodeoxyribonuclease IV) (apurinase) [Mycobacterium tuberculosis C] >gi|134149133|gb|EBA41178.1| endonuclease IV end (endodeoxyribonuclease IV) (apurinase) [Mycobacterium tuberculosis str. Haarlem] >gi|148504597|gb|ABQ72406.1| endonuclease IV [Mycobacterium tuberculosis H37Ra] >gi|148720402|gb|ABR05027.1| endonuclease IV end [Mycobacterium tuberculosis F11] (252 aa)
Score = 216, Expect = 1.0e-15, Identities = 76/261 (29%), Positives = 117/261 (44%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDG-NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILET 288
           +L+GSHV            L   E +G +   +F G PQ++   +      D+A  L     P     I VHAPYLINL S     R      L         I +  +++H G   D +    I+       KA++  + +V + +E  AG    +   F+ ++++   V     IG CLDTCH   +G  ++D    ++  +  +DL     +H NDS++E GS +DRH N+G G++  D LV      K A  P I ET
  S:     1 MLIGSHVS-------PTDPLAAAEAEGADVVQIFLGNPQSWKAPKPR----DDAAALKAATLP-----IYVHAPYLINLASANNRVRIPSRKILQETCAAAADIGAAAVIVHGGHVADDND---IDKGFQRWRKALDRLETEVPVYLENTAGGDHAMARRFDTIARLWD-VIGDTGIGFCLDTCHTWAAGEALTDAVDRIKAITGRIDL-----VHCNDSRDEAGSGRDRHANLGSGQIDPDLLVAAV---KAAGAPVICET 234
>gi|84498623|ref|ZP_00997386.1| endonuclease IV [Janibacter sp. HTCC2649] >gi|84381156|gb|EAP97041.1| endonuclease IV [Janibacter sp. HTCC2649] (264 aa)
Score = 214, Expect = 1.5e-15, Identities = 59/195 (30%), Positives = 93/195 (47%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDR-NVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKI---VSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           + VHAPY+IN+ +     R      L   ++   +I +K +++H G    +D   V      DN  KAIEATD  + + +E  AG  + +    E ++K+   +       ++G CLDTCH H  G  +      +   +  +DL     +H NDS++   S  DRH N G G++  D L   A   + A  P + ETP
  S:    61 LYVHAPYIINVATTNNRIRIPSRKLLQQHVDAAAEIGAKGLIVHGGHVGKTDDPEVGF----DNWRKAIEATDLKLPLLLENTAGGDNAMARYLERIAKVWDAIGSASQADQVGFCLDTCHAHAGGNKLDTVVDDILAITGRIDL-----VHCNDSRDAFDSGADRHANFGAGQIDADLL---AGVVRSAGAPVVCETP 247
>gi|145225669|ref|YP_001136347.1| endonuclease IV [Mycobacterium gilvum PYR-GCK] >gi|145218155|gb|ABP47559.1| Endonuclease IV [Mycobacterium gilvum PYR-GCK] (250 aa)
Score = 212, Expect = 3.2e-15, Identities = 78/276 (28%), Positives = 123/276 (44%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDG-NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP--YRDDKPIYKQEIIN 303
           +L+GSHV            L   E DG +    F G PQ++ +        D+A  L     P     I VHAPYLIN+ S     R      L    +  ++I +  +++H G A D+D +           KA+ +   DV + +E  AG    +  +F+ ++++   + +   IG CLDTCH   +G  + D  + ++  +  +DL     +H NDS++  GS  DRH N G G++    LV        A  P I ET    R D   + +E +N
  S:     1 MLIGSHVHGD-------DPLAAAEADGADVVQFFLGNPQSWKKPPPR----DDADVLKAASMP-----IYVHAPYLINVASANNRVRIPSRKILQDTCDAASEIGATAVIVHGGHADDNDMDAGFERWV----KALASLKTDVPVYLENTAGGDHAMARHFDTIARLWDHIGDMG-IGFCLDTCHAWAAGEALVDAVERIKGITGRIDL-----VHCNDSRDAAGSGADRHANFGTGQIDPQLLVAVV---TAAGAPVICETSDEGRKDDIAFLREHVN 250
>gi|120402272|ref|YP_952101.1| endonuclease IV [Mycobacterium vanbaalenii PYR-1] >gi|119955090|gb|ABM12095.1| Endonuclease IV [Mycobacterium vanbaalenii PYR-1] (259 aa)
Score = 211, Expect = 3.5e-15, Identities = 74/263 (28%), Positives = 119/263 (45%)
  Q:    26 NKLLLGSHVGFKAKNYLVGSVLETLEYDG-NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILET 288
           + +L+GSHV            L   E DG +    F G PQ++ +    +    +A  L     P     I VHAPYLIN+ S     R      L    +  ++I +  +++H G A D+D +           KA+ +  +DV + +E  AG    +  +F+ ++++   + +   IG CLDTCH   +G  + D  + ++  +  +DL     +H NDS++  GS  DRH N G G++    LV      K A  P I ET
  S:     9 DAVLIGSHVHGD-------DPLAAAEADGADVVQFFLGNPQSWKKPPPRE----DAEVLKASPVP-----IYVHAPYLINVASANNRVRIPSRKILQDTCDAASEIGATAVIVHGGHADDNDMDAGFERWV----KALASLKSDVPVYLENTAGGDHAMARHFDTIARLWDHIGDTG-IGFCLDTCHAWAAGEALIDAVERIKGITGRIDL-----VHCNDSRDAAGSGADRHANFGSGQIDPQLLVAVV---KAAGAPVICET 243
>gi|167948617|ref|ZP_02535691.1| endonuclease IV [Endoriftia persephone 'Hot96_1+Hot96_2'] (114 aa)
Score = 209, Expect = 6.0e-15, Identities = 40/100 (40%), Positives = 64/100 (64%)
  Q:   197 VKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPI 296
           +++K R+GVCLDTCH   +G D+   +   QT  EF + +   Y+  +HLNDSK E+G R DRH ++G GK+G++      ++ +  ++P +LET   DD P+
  S:     1 MEDKSRVGVCLDTCHSFVAGYDLRSAEACEQTFAEFERIVGFDYLCGMHLNDSKPELGQRVDRHHSLGQGKIGWECFRYIMNDPRFDDIPMVLETI--DDTPL 101
>gi|108803988|ref|YP_643925.1| endonuclease IV [Rubrobacter xylanophilus DSM 9941] >gi|108765231|gb|ABG04113.1| apurinic endonuclease (APN1) [Rubrobacter xylanophilus DSM 9941] (289 aa)
Score = 208, Expect = 8.6e-15, Identities = 61/196 (31%), Positives = 103/196 (52%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKA--IEAT--DNDVIICVETMAGKGSEVGINFEEVSKI--VSGVKNKKRIGVCLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKV---GFDYLVKWAHNEKLANVPKILETPY 290
           +V HA YLINL SP    R   +  L  E+    ++ + L+V+H GS         +  +A  L+ A  + A+         VE   G G+++  +F  + ++  ++GV+      VC+DT H   +G D+S P+       E  ++LD   + ++HLND++N +GSR+D H  +G G++    F  L        L  +P ++ETPY
  S:    67 VVAHAKYLINLSSPDGELRERSVRALAAELVAAGRLGADLVVVHAGSHGGEGEERGMERLARGLDAARGLAASLGGRAAEPVVENSCGAGTQLCSSFAALGRLARLAGVR------VCVDTAHAFVAGYDLSTPEGAAGVAGELGEHLD-GRVALLHLNDARNGLGSRRDGHAKVGEGRIPPGSFAALFA-----ALPGLPAVMETPY 262
>gi|192808835|ref|ZP_03037511.1| apurinic endonuclease Apn1 [Geobacillus sp. Y412MC10] >gi|192802806|gb|EDV79310.1| apurinic endonuclease Apn1 [Geobacillus sp. Y412MC10] (282 aa)
Score = 200, Expect = 6.1e-14, Identities = 70/264 (26%), Positives = 116/264 (43%)
  Q:    25 KNKLLLGSHVGFKAKNYLVGSVLETLEYDGN----CFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLG---SPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSG-IDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILET 288
           K+K+ +GSHV  +      G  L   ++        +  F   P++   K  D        K  +E+  +     + H PY  N+    +  E+   L ++ L  ++       S  IV+H G     +      +I   +N  + +      + +E  AG    +G+  EE  K+       ++IG CLDTCH+  +G  D+S+ D+ L    +         +HLNDSK   GSRKDRH  IG G +G + L +     +LA    +LE+
  S:     2 KSKVRIGSHVSTR------GGFLAAAQHAAGIGSLAYQYFPKNPRSLHLKTPDVRNAAACAKFCQEQGLV----SIAHTPYPTNMAVGLTRGEAFYQLTVDSLKNDLMIAEACGSLGIVVHFGHLKSENVLEGYQNIIRCMNDVLSSWTGRAKLLIENQAGDHGSMGMTLEESVKVRQLADYPEKIGFCLDTCHLFAAGGWDLSNTDELLARGKELAYWESAVAVHLNDSKYGAGSRKDRHARIGQGMIGTEALKRLVLAPELAGKAFVLES 263
>gi|23007412|ref|ZP_00049293.1| COG0648: Endonuclease IV [Magnetospirillum magnetotacticum MS-1] (260 aa)
Score = 198, Expect = 1.3e-13, Identities = 60/213 (28%), Positives = 100/213 (46%)
  Q:    59 VFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNK---KRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLV 271
           +F G PQ++   E       EA+K       L    +VVHAPY+IN+ SP    R      L   ++    + +  +V+H G  + +  + A     DN  KAI+A   DV + +E  AG    +    + +  + + V+     + +G CLDTCH    GID++     +   +  +DL     +HLN+S++  GS  DRH  +  G +  + L+
  S:    26 IFLGDPQSWKGPEFTFPGGAEALKDAATAADL---ELVVHAPYVINVASPNNRIRIPSRKLLQQIVDGAAAVGATGVVVH-GGHVTAKEDPAKGF--DNWRKAIDALQTDVTVYIENTAGGDFSMARRLDRIEGLWAAVQQADGAENVGFCLDTCHAWAGGIDLTTAVDDVRAITGRVDL-----VHLNNSRDTAGSGADRHAGLTAGTIDPELLL 230
>gi|183981020|ref|YP_001849311.1| endonuclease IV (apurinase) [Mycobacterium marinum M] >gi|183174346|gb|ACC39456.1| endonuclease IV (apurinase) [Mycobacterium marinum M] (252 aa)
Score = 197, Expect = 1.7e-13, Identities = 75/276 (27%), Positives = 125/276 (45%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY--RDDKPIYKQEIIN 303
           +L+GSHV    ++ L  +  E  E       +F G PQ++   +  +    +A +L     P     I VHAPYLINL S     R      L    +    I +  +++H G   D +    ++       KA++    DV + +E  AG    +  +F+ ++++   V     IG CLDTCH   +G  +      ++  +  +DL     +H NDS++  GS +DRH N+G G++  + LV      + A+ P I ET    R D   + +E +N
  S:     1 MLIGSHV--SPQDPLAAAQAEGAE----VVQIFLGNPQSWKAPKPRE----DAAQLKAAALP-----IYVHAPYLINLASANNKVRIPSRKILQQTCDAAADIGAAAVIVHGGHVADDND---LDEGFQRWRKALDQLQTDVPVYLENTAGGEHAMARHFDTIARLWD-VIGDTGIGFCLDTCHAWAAGEQLVHGVDRIKAVTGRIDL-----VHCNDSRDAAGSGRDRHANLGAGQIDPELLVAAV---RAADAPIICETAEEGRKDDIAFLREKLN 251
>gi|108797946|ref|YP_638143.1| endonuclease IV [Mycobacterium sp. MCS] >gi|119867042|ref|YP_936994.1| endonuclease IV [Mycobacterium sp. KMS] >gi|126433608|ref|YP_001069299.1| endonuclease IV [Mycobacterium sp. JLS] >gi|108768365|gb|ABG07087.1| Endonuclease IV [Mycobacterium sp. MCS] >gi|119693131|gb|ABL90204.1| Endonuclease IV [Mycobacterium sp. KMS] >gi|126233408|gb|ABN96808.1| Endonuclease IV [Mycobacterium sp. JLS] (268 aa)
Score = 196, Expect = 2.1e-13, Identities = 72/261 (27%), Positives = 115/261 (44%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDG-NCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILET 288
           +L+GSHV    +N      L   E DG +    F G PQ++ + +  +    +A  L     PL      VHAPYLIN+ S     R      L    +   ++ +  +++H G A D D             KA++  +  V + +E  AG    +   F+ + ++   + +   IG CLDTCH   +G  + D    ++  +  +DL     +H NDS++  GS  DRH N G G++    LV      + A+ P I ET
  S:    20 VLIGSHV----RN---DDPLAAAEADGADVVQFFLGDPQSWKKPKPRE----DAEVLKASSIPLY-----VHAPYLINVASANNRVRIPSRKILQDTCDAAAEVGATAVIVHGGHADDKDMEAGFERWV----KALDRLETTVPVYLENTAGGEHAMARYFDTIGRLWDHIGDYG-IGFCLDTCHAWAAGEALVDAVSRIKRITGRIDL-----VHCNDSRDAAGSGADRHANFGNGQIDPQLLVAVV---QAADAPVICET 252
>gi|118616535|ref|YP_904867.1| endonuclease IV [Mycobacterium ulcerans Agy99] >gi|166224288|sp|A0PM27|END4_MYCUA Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|118568645|gb|ABL03396.1| endonuclease iv (apurinase), End [Mycobacterium ulcerans Agy99] (252 aa)
Score = 196, Expect = 2.2e-13, Identities = 75/276 (27%), Positives = 124/276 (44%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPY--RDDKPIYKQEIIN 303
           +L+GSHV    ++ L  +  E  E       +F G PQ++      +    +A +L     P     I VHAPYLINL S     R      L    +    I +  +++H G   D +    ++       KA++    DV + +E  AG    +  +F+ ++++   V     IG CLDTCH   +G  +      ++  +  +DL     +H NDS++  GS +DRH N+G G++  + LV      + A+ P I ET    R D   + +E +N
  S:     1 MLIGSHV--SPQDPLAAAQAEGAE----VVQIFLGNPQSWKAPRPRE----DAAQLKAAALP-----IYVHAPYLINLASANNKVRIPSRKILQQTCDAAADIGAAAVIVHGGHVADDND---LDEGFQRWRKALDQLQTDVPVYLENTAGGEHAMARHFDTIARLWD-VIGDTGIGFCLDTCHAWAAGEQLVHGVDRIKAVTGRIDL-----VHCNDSRDAAGSGRDRHANLGAGQIDPELLVAAV---RAADAPIICETAEEGRKDDIAFLREKLN 251
>gi|15828008|ref|NP_302271.1| endonuclease IV [Mycobacterium leprae TN] >gi|399426|sp|P30770|END4_MYCLE Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|581336|emb|CAA78670.1| endonuclease [Mycobacterium leprae] >gi|13093561|emb|CAC30843.1| putataive endonuclease IV (apurinase) [Mycobacterium leprae] (252 aa)
Score = 191, Expect = 8.2e-13, Identities = 75/261 (28%), Positives = 118/261 (45%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLN---KAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILET 288
           +L+GSHV   + + L  + +E      +   +F G PQ++    L      +A  L     P     + VHAPYLIN+ S     R      L    +    I +  +V+H G   D       N + D      KA++    DV + +E  AG    +   F+ ++++   V  +  IG CLDTCH   +G  +      ++  +  +DL     +H NDSK+E GS +DRH N+G G++  + LV      K+A  P I ET
  S:     1 MLIGSHV--SSTDPLAAAEVE----GADVVQIFLGNPQSWKAPTLRS----DADVLKATALP-----VYVHAPYLINVASANSRVRIPSRKILQQTCDAAADIGAAAVVVHGGYVADD------NDLEDGFQRWRKALDQLQTDVPVYLENTAGGDHAMARRFDTIARLWD-VIGETGIGFCLDTCHAWAAGEGLIHVVDRIKAITGRIDL-----VHCNDSKDEAGSGRDRHANLGSGQIDAELLVAAV---KVAGAPVICET 234
>gi|134103773|ref|YP_001109434.1| endonuclease IV [Saccharopolyspora erythraea NRRL 2338] >gi|133916396|emb|CAM06509.1| endonuclease IV [Saccharopolyspora erythraea NRRL 2338] (256 aa)
Score = 187, Expect = 2.1e-12, Identities = 51/195 (26%), Positives = 94/195 (48%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           + +H+PY+IN+ S     R      +         + ++ +V+H G    D D    + +      +  +    +V + +E  AG  + +   F+ ++++   V  +   G CLDTCH H +G ++ D    ++  +  +DL     +HLNDS++  GS +DRH NIG G++  + LV    +   A  P ++ETP
  S:    53 VFIHSPYVINVASLNNRIRIPSRKLVTQHAKAAAAVGAQGLVVHGGHVTKDDDPAEGVANWRKMFERQADEGGFEVPVLIENTAGGANAMARRFDALARLWDAV-GEFGAGFCLDTCHAHAAGEELLDVVDRVKTITGRIDL-----VHLNDSRDGFGSSRDRHANIGAGEIDPELLVAVCSS---AGAPVVVETP 239
>gi|169191075|ref|ZP_02850947.1| AP endonuclease family 2 [Paenibacillus sp. JDR-2] >gi|169002286|gb|EDS49177.1| AP endonuclease family 2 [Paenibacillus sp. JDR-2] (149 aa)
Score = 182, Expect = 8.0e-12, Identities = 47/139 (33%), Positives = 77/139 (55%)
  Q:   171 ICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPD-QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHN-EKLANVPKILETPYRDDKPIYKQEIINLNSKEW 309
           + +E  +G+ + +G   EE+++I        ++  CLDTCHM  SG+   + D + L++      L ++  +H NDS    G+R+DRH  +G G +G +  +KW  +   LA VP ILETP  +D    +Q  +NL  +EW
  S:    11 LLIEIQSGEHTFMGTTIEELAQIRGLCAEPAKLAFCLDTCHMFASGLWHGETDAEWLKKAVSLGVLEHVAAVHFNDSMFAAGARRDRHAALGSGHIG-EAGLKWLMSVPALAGVPFILETPSDEDGSYGRQ--LNL-MREW 147
>gi|111018888|ref|YP_701860.1| endonuclease IV [Rhodococcus sp. RHA1] >gi|110818418|gb|ABG93702.1| deoxyribonuclease IV [Rhodococcus sp. RHA1] (256 aa)
Score = 171, Expect = 1.7e-10, Identities = 53/196 (27%), Positives = 92/196 (46%)
  Q:    94 NIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALD-SDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           ++VVH+ Y+IN+ S     R    N +  +      I +  +V+H G   D  D N  I +      +  +     V I +E  AG    +  +F+ + ++   V +    G CLDTCH    G ++    + ++  +  +DL     +HLN+S++E  S +DRH N+  G +  + L   A   + A+ P +LETP
  S:    53 DVVVHSSYVINVASLNNRLRMPSRNAVAQQAQAAADIGAFGLVVHGGHVRDGEDVNAGIVNWRKLFERQADKGGFPVPILIENTAGGDFAMARHFDAIDRLWQEVGDFG-AGFCLDTCHAWAGGEELVGVVERIKAITGRIDL-----VHLNNSRDEFNSARDRHANLAEGTIDAELL---AEVVRTADAPVVLETP 240
>gi|50843670|ref|YP_056897.1| endonuclease IV [Propionibacterium acnes KPA171202] >gi|50841272|gb|AAT83939.1| probable endonuclease IV [Propionibacterium acnes KPA171202] (251 aa)
Score = 169, Expect = 2.9e-10, Identities = 45/167 (26%), Positives = 81/167 (48%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVS---KIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIG 261
           +VVH+ ++IN+ S     R      L   ++   ++ +  +V+H G     +    I    DN  KAI+  +  V + VE  AG  + +    E +S   + +      + +G CLDTCH   +G+D++     +   +  ++L     +H NDS+  +GS +DRH N+G
  S:    62 LVVHSAFVINVASLNNRIRIPSRKLLQQTLDAAAEVGAMGVVVHGGHVRAGE---PIEKGQDNWRKAIDGLEMSVPLFVENTAGGDNAMARFLERLSGTWEAIGAASGHENVGFCLDTCHAFAAGLDMASLVDDVRGITGRINL-----VHANDSQGAVGSGRDRHANLG 223
>gi|171853833|emb|CAM11782.1| Putative endonuclease IV, fragment [Candidatus Phytoplasma australiense] (83 aa)
Score = 165, Expect = 8.6e-10, Identities = 35/80 (43%), Positives = 51/80 (63%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGS 107
           L+LGSHV  +  +   GSV   L    N FMV++G P+N +RKE D++ I EA++L  + N L  +N V HAPY++NL +
  S:     2 LILGSHVPMQKPDNFKGSVKTALAMRANSFMVYSGAPKNTIRKEQDKSQIKEALELAFQNN-LFCDNFVGHAPYIVNLAN 80
>gi|159040550|ref|YP_001539803.1| endonuclease IV [Salinispora arenicola CNS-205] >gi|157919385|gb|ABW00813.1| apurinic endonuclease Apn1 [Salinispora arenicola CNS-205] (263 aa)
Score = 155, Expect = 1.1e-08, Identities = 50/196 (25%), Positives = 95/196 (48%)
  Q:    94 NIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND----VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           +I VHAPY+IN+ +     R      L+        + ++ +++H G  +++  ++A     DN  KA E         V + +E  AG  +      + ++++   + + + +G CLDTCH H  G ++      ++  +  +DL     +H N+SK    S +DRHDN+  G +  + +V      + A+ P ++ETP
  S:    52 DIYVHAPYVINVATLNNRIRIPSRKLLLAHARAAAAVGARGLIVH-GGHVNAGDDLATGF--DNWRKAFEYAAESGGFGVPVLIENTAGGNNACARRLDALARLWDAIGDHE-VGFCLDTCHAHAGGEELLGLVDRIKAITGRIDL-----VHANNSKGAFNSGQDRHDNLTGGTIDPEQVVTVI---RAADAPVVVETP 239
>gi|54026642|ref|YP_120884.1| endonuclease IV [Nocardia farcinica IFM 10152] >gi|54018150|dbj|BAD59520.1| putative endonuclease IV [Nocardia farcinica IFM 10152] (256 aa)
Score = 150, Expect = 4.1e-08, Identities = 54/196 (27%), Positives = 88/196 (44%)
  Q:    94 NIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND----VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           ++VVH+ Y IN+ S     R    N +  +      + +  +V+H G  + SD  +      DN  K  +   +     V I +E  AG    +  +F+ + ++   V  +   G CLDTCH    G D+    + ++  +  +DL     +HLN S++E  S  DRH N   G +    L   A   + A  P +LETP
  S:    53 DVVVHSSYQINVASLNNRLRMPSRNAVAQQAKAAADLGAFGLVVH-GGHVRSDAEIETG--IDNWRKLFQRQQDKGGFAVPILIENTAGGNHAMARHFDMIGRLWDAV-GEFGAGFCLDTCHAWAGGEDLVGVVERIKGITGRIDL-----VHLNSSRDEFNSGADRHANFADGTIDPQLL---AEVCRTAGAPVVLETP 240
>gi|20807725|ref|NP_622896.1| endonuclease IV [Thermoanaerobacter tengcongensis MB4] >gi|20516277|gb|AAM24500.1| Endonuclease IV [Thermoanaerobacter tengcongensis MB4] (288 aa)
Score = 150, Expect = 4.5e-08, Identities = 56/180 (31%), Positives = 92/180 (51%)
  Q:    77 IDEAVKL-MKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN----DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH--DSG--IDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDR 256
           I E + L +KE        I +HAPY INL + +E         +I  +   N + +K +  HPGSA   DR  A++     L + I+  D+     + +C ETM GK +++G   EEV ++    +  +R+   +D  H+H  D+G    I D ++ L    KYL     KVIH++ S+ E   + ++
  S:    47 ISEKLALQLKENAEKFNITITIHAPYYINLAAAEEEKIKNSKRYIIESLTAGNLMGAKRVTFHPGSA-SLDRREALDRAKRVLKEVIKEADDLGLGHITLCPETM-GKKNQLG-TLEEVLEL---CQLDERLLPTVDFAHLHARDNGRFKSIEDYEEVLNTIEKYLGKDRAKVIHVHFSRIEFTEQGEK 229
>gi|145597066|ref|YP_001161363.1| endonuclease IV [Salinispora tropica CNB-440] >gi|145306403|gb|ABP56985.1| Endonuclease IV [Salinispora tropica CNB-440] (263 aa)
Score = 147, Expect = 9.6e-08, Identities = 50/196 (25%), Positives = 95/196 (48%)
  Q:    94 NIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI----EATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           ++ VHAPY+INL +     R      L+        + ++ +++H G  +++  ++A     DN  KA     E+    V + +E  AG  +      + ++++   + + + +G CLDTCH +  G ++      ++  +  +DL     IH N+SK    S +DRHDN+  G +  + +V      + A  P ++ETP
  S:    52 DLYVHAPYVINLATLNNRIRIPSRKLLLAHAQAAAAVGARGLIVH-GGHVNAGDDLATGF--DNWRKAFAYAAESGGFGVPVLIENTAGGANACARRLDALARLWDAIGDHE-VGFCLDTCHAYAGGEELLGLVDRIKAITGRIDL-----IHANNSKGTFNSGQDRHDNLTGGTIDPEQVVAVI---RAAGAPVVVETP 239
>gi|8928097|sp|O86954|END4_THENE Probable endonuclease 4 (Endonuclease IV) (Endodeoxyribonuclease IV) >gi|3378517|emb|CAA08862.1| putative endonuclease IV [Thermotoga neapolitana] (108 aa)
Score = 145, Expect = 1.7e-07, Identities = 33/80 (41%), Positives = 46/80 (57%)
  Q:   210 CHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           CH  DSG DI+  +     L E      L  +K+IHLNDSK  +G+ KDRH+ IG G +G      +   +++  +P ILETP
  S:     1 CHGFDSGYDITKKEGVESLLSEIENLFGLERLKMIHLNDSKYPLGAAKDRHERIGSGFIGEAGFAVFFSFKEVQRIPWILETP 83
>gi|530469|emb|CAA83807.1| similar to AP-endonucleases [Mycoplasma capricolum subsp. capricolum ATCC 27343] (71 aa)
Score = 144, Expect = 1.9e-07, Identities = 32/60 (53%), Positives = 40/60 (66%)
  Q:   250 IGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIINLNSKEW 309
           + S KDRH NIGYG VGFD LV    ++  +N+ KILETPY D K  YK EI +L +K +
  S:     8 LDSHKDRHANIGYGFVGFDTLVNVVFDKDFSNISKILETPYIDKKAPYKIEIEDLLNKTF 67
>gi|147918712|ref|YP_687565.1| hypothetical protein LRC22 [uncultured methanogenic archaeon RC-I] >gi|110622961|emb|CAJ38239.1| hypothetical protein [uncultured methanogenic archaeon RC-I] (265 aa)
Score = 143, Expect = 2.5e-07, Identities = 48/191 (25%), Positives = 92/191 (48%)
  Q:    95 IVVHAP------YLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEV----SKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLD--LSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKI 285
           I+VHAP       +++ GS  E  R+     L   I+ + ++ ++L+++HPG      R V+   +   + +      N V + +E M G     G  +       +  +  V ++  +G+CLD CH      ++S  D     F +Y++  L Y + +H++D+  E G        IG G++ +++L     +  L  VP+I
  S:    46 IIVHAPEKFGDGTILDAGSEDEVQRTRATEMLKRTIDISVRLQAELVIIHPGGVFREHRTVSPERLIRTMAELKACAGNRVELVLENMPGYYRTGGTLWHPCLLTGADEIVAVLDRTDVGLCLDVCHAKLY-CNVSGHD-----FKQYIETLLPYARHLHVSDAMGEAGEGL----QIGEGEIDWEWLASVTRDLDLVAVPEI 238
>gi|126466079|ref|YP_001041188.1| endonuclease IV [Staphylothermus marinus F1] >gi|126014902|gb|ABN70280.1| Endonuclease IV [Staphylothermus marinus F1] (282 aa)
Score = 142, Expect = 3.4e-07, Identities = 59/189 (31%), Positives = 103/189 (54%)
  Q:    78 DEAVKLMKE--KNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN----DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH--DSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKD-RHDNIGYGKVG 266
           ++A KL +E  KN +LL    +HAPY INL S K       +++LI  I   + +++ ++V H G   + +RN A+  + ++L + IE  +      +I+  ET AGK S++G   EE+  I S + N + +   +D  H+H   +G  I+  D   + +E   K L    +  +H + SK E  S+ + RH ++   + G
  S:    48 EKAYKLGEEARKNDILLS---IHAPYFINLASSKNKVIEASISRLIKSIEAASWMNAYIVVFHLGYYGEYNRNEALRKVINSLKQVIEYRNTMGYKRIILGPET-AGKKSQIG-GLEEIINISSLLDNVRPV---IDWAHLHARSNGKLINSIDNVIEVIEIIEKNLGGEAVNPLHSHFSKIEYSSKGEIRHHSLKEKEYG 240
>gi|167037494|ref|YP_001665072.1| xylose isomerase domain-containing protein [Thermoanaerobacter pseudethanolicus ATCC 33223] >gi|166856328|gb|ABY94736.1| Xylose isomerase domain protein TIM barrel [Thermoanaerobacter pseudethanolicus ATCC 33223] (292 aa)
Score = 140, Expect = 5.8e-07, Identities = 52/172 (30%), Positives = 86/172 (50%)
  Q:    78 DEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN----DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH--DSG--IDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNE 249
           ++  K +KE        I VHAPY INL +  ++        LI  +     + +K +  HPGSA +  R  A+      L + ++  ++    D+ +C ETM GK +++G   EEV ++ +     KRI   +D  H+H  D+G    I D  + L+   +YL     K IH++ S+ E
  S:    52 EKMAKELKEGAQKFNITITVHAPYYINLATTDKTKMENSKRYLIDSLIAGKWMGAKRVTFHPGSATEGTRKEALERAKKLLKEILKEIEDKGLTDITLCPETM-GKKNQLG-TLEEVLELCN---VDKRIIPTIDFAHLHARDTGRFKSIEDYAEVLDIIERYLGKERAKKIHVHFSRIE 226
>gi|118431731|ref|NP_148385.2| endonuclease IV [Aeropyrum pernix K1] >gi|116063053|dbj|BAA81115.2| endonuclease IV [Aeropyrum pernix K1] (280 aa)
Score = 136, Expect = 1.7e-06, Identities = 63/205 (30%), Positives = 100/205 (48%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPG--SALDSDRNVAINHIADNLNKAIEATDNDV---IICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH--DSGIDISDPDQ---TLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDR-HDNIGYGKVGFDY-LVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           +HAPY +NL SP +S     + +L   +  +  + S  +V+HPG    L S R  A+  + + LN+ IE+  + V    I  ETM GK S+VG + EE  +I     N  R   C+D  H++    G  ++  DQ    +E     L    +  +H + SK E G   +R H  +     G D+ +V  A+ E   N   I E+P  +   +  + I
  S:    65 MHAPYYVNLSSPDDSVVERSIKRLYDSMIASEWMGSYAVVVHPGYYKGLKS-REEAVKRVIEALNRLIESLPSWVKTPWIAPETM-GKQSQVG-SLEETVEI---CLNTPRCRPCVDWAHLYARAEGKFVTSVDQVVKAIEYIESNLGREAVDPLHTHFSKIEYGKGGERMHHTLREEGYGPDWRIVCRAYKETGINAVVISESPILEKDALLMKSI 275
>gi|167040156|ref|YP_001663141.1| xylose isomerase domain-containing protein [Thermoanaerobacter sp. X514] >gi|166854396|gb|ABY92805.1| Xylose isomerase domain protein TIM barrel [Thermoanaerobacter sp. X514] (292 aa)
Score = 134, Expect = 2.9e-06, Identities = 51/172 (29%), Positives = 85/172 (49%)
  Q:    78 DEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN----DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH--DSG--IDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNE 249
           ++  K +KE        I VHAPY INL +  ++        LI  +     + +K +  HPGS  +  R  A+      L + ++  ++    D+ +C ETM GK +++G   EEV ++ +     KRI   +D  H+H  D+G    I D  + L+   +YL     K IH++ S+ E
  S:    52 EKMAKELKEGAQKFNITITVHAPYYINLATTDKTKMENSKRYLIDSLIAGKWMGAKRVTFHPGSGAEGTRKEALERAKKLLKEILKEIEDKGLTDITLCPETM-GKKNQLG-TLEEVLELCN---VDKRIIPTIDFAHLHARDNGRFKSIEDYAEVLDIIERYLGKERAKKIHVHFSRIE 226
>gi|196253948|ref|ZP_03152547.1| Xylose isomerase domain protein TIM barrel [Clostridium thermocellum DSM 4150] >gi|196196623|gb|EDX91521.1| Xylose isomerase domain protein TIM barrel [Clostridium thermocellum DSM 4150] (296 aa)
Score = 133, Expect = 4.5e-06, Identities = 44/171 (25%), Positives = 86/171 (50%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN----DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGF 267
           +HAPY IN+ SP+E  R      +I  +     + +K IV+H GS    D+  A+   A   ++ ++  D+    D+++C E + GK +++G + EE+ +I    K  +R+   +D  H+H  G        T+E+F + +++           +N +G+ K R  +  + ++ F
  S:    70 IHAPYYINMASPEEEKRIKSKGYIIDCMRLAKWMGAKRIVVHTGSYSKVDKKWALEISAKLFDEVLKEADSLGLTDIVLCPEVL-GKNNQIG-SLEEIIEI---CKTNERLFPTIDFGHIHARG---QGSLNTVEDFERIINM----------LENSLGTEKVRELHCHFSRIEF 226
>gi|47157040|gb|AAT12397.1| DNA lyase/endonuclease 4 [Antonospora locustae] (194 aa)
Score = 131, Expect = 7.5e-06, Identities = 43/156 (27%), Positives = 79/156 (50%)
  Q:    26 NKLLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGS 181
           +K L+G+H+      + V   ++ L+       + +    NF      + + DE V   +E +    E I+ HA YL+NL +P E     G + L+ ++ R N +  K+  +HPGS ++     A+  +++NLN+ +    N V++ +E MAG+GS
  S:    46 HKHLVGAHLSISKGIHTVQEQMDMLKAHTCAMFLKSQRTYNF------KKIKDEDVSRFRE-HVRFPELILPHASYLVNLANP-EVMSGKGFDVLVDDLERCNLLGIKMYNIHPGSDVNKLGRGALELVSENLNRVLSIVPN-VMVLLENMAGQGS 192
>gi|118727620|ref|ZP_01576215.1| Xylose isomerase-like TIM barrel [Clostridium cellulolyticum H10] >gi|118663018|gb|EAV69684.1| Xylose isomerase-like TIM barrel [Clostridium cellulolyticum H10] (288 aa)
Score = 127, Expect = 2.1e-05, Identities = 46/174 (26%), Positives = 86/174 (49%)
  Q:    94 NIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDR----NVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGF 267
           ++ +HAPY IN+ S +E  R      ++  +     + +K IV+H GS     R     +AI  + + L  +  A   D+ IC E + GK +++G   EE+ ++    KN +R+   +D  H+H  G+ + +   + E+F K +D  YI        +N IG  + +  +  + ++ F
  S:    64 SVSIHAPYYINMSSEEEDKRENSKRYIMETLQVAKWMGAKRIVVHTGSTSKLGREKSLELAIQVLKETLQMSDAAGFGDISICPEVL-GKHNQLG-TLEEIMEM---CKNDERLIPTIDFGHIHARGLGMLN---SQEDFEKVID--YI--------ENSIGKERAKRIHCHFSRIEF 223
>gi|160946014|ref|ZP_02093240.1| hypothetical protein FAEPRAM212_03547 [Faecalibacterium prausnitzii M21/2] >gi|158443745|gb|EDP20750.1| hypothetical protein FAEPRAM212_03547 [Faecalibacterium prausnitzii M21/2] (289 aa)
Score = 121, Expect = 1.1e-04, Identities = 37/117 (31%), Positives = 59/117 (50%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN----DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH 213
           VHAPY I++ S +E  R   +  L+        +  + I+ H GS     R  A+    D + +A+ A D     D+ +C ETM GK  ++G   +EV  +  GV +  RI  C+D  H++
  S:    72 VHAPYYISMSSLEEDKRLNSIQYLLQSAAVCRALGGRRIIFHSGSCGKQSREAALEKALDTMRRAVAALDEAGFGDMTLCPETM-GKIGQLG-TLDEVLTLC-GVDS--RITPCIDFGHLN 187
>gi|9628240|ref|NP_042826.1| AP endonuclease class II [African swine fever virus] >gi|780502|gb|AAA65362.1| AP endonuclease class II >gi|162849515|emb|CAN10482.1| AP endonuclease class II [African swine fever virus OURT 88/3] >gi|1097525|prf||2113434ET AP endonuclease:ISOTYPE=class II (296 aa)
Score = 117, Expect = 2.7e-04, Identities = 55/179 (30%), Positives = 95/179 (53%)
  Q:    91 LLENIVVHAPYLINLGSPKE---STRSLGLNQLIV-EINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGIN-FEEVSKIVSGVKNK--KRIGVCLDTCHMHDSGIDISDPD------QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDY 269
           LL+ IV H  +++  G+  +   S RS  +   I  E+    ++  K +VLH G+       V    I + L K I+  +  V+I +ET   K      +  E++ ++   ++N   K+IG+C+DT H+  SG++IS  +      ++LE     +  S+I + HLND+  E GS  DRH ++  G +   Y
  S:    64 LLKMIVKHNLWVVAHGTYLDVPWSRRSAFVTHFIQQELLICKEVGIKGLVLHLGA-------VEPELIVEGLKK-IKPVEG-VVIYLETPHNKHHTYKYSTMEQIKELFLRIRNTRLKQIGLCIDTAHIWSSGVNISSYNDAGQWLRSLENIHSVIPPSHI-MFHLNDAATECGSGIDRHASLFEGMIWKSY 245
>gi|124027908|ref|YP_001013228.1| endonuclease IV [Hyperthermus butylicus DSM 5456] >gi|123978602|gb|ABM80883.1| predicted Endonuclease IV [Hyperthermus butylicus DSM 5456] (283 aa)
Score = 117, Expect = 3.0e-04, Identities = 46/177 (25%), Positives = 84/177 (47%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSAL-DSDRNVAINHIADNLNKAIEATDND----VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSG-----IDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDR-HDNIGYGKVGFDYLV 271
           + +HAPY IN  SP + T      +LI  +   + +++  +V HPG    +S    A+    +NL    E  +      V I  ET  G+ ++VG + EEV  I   +++ +     +D  H+H        + + D  + +E   + L    +K +H + SK   G   ++ H  +  G+ G D+ +
  S:    65 VSMHAPYFINFASPDKQTVEKSRERLIASVRAASWMNAYAVVFHPGYYKGNSSPEEALQRTIENLRSVDEYIEQQGIKGVWIAPET-TGRTAQVG-SVEEVVAICRELRHARP---AVDWAHIHARSLGKHVVSVDDVVRIVEYIERELGTWAVKPLHTHFSKIGYGEGGEKEHHTLAEGEYGPDWRI 247
>gi|162849342|emb|CAN10233.1| AP endonuclease class II [African swine fever virus Benin 97/1] (296 aa)
Score = 114, Expect = 5.7e-04, Identities = 29/82 (35%), Positives = 51/82 (62%)
  Q:   188 EEVSKIVSGVKNK--KRIGVCLDTCHMHDSGIDISDPD------QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDY 269
           E++ ++   ++N   K+IG+C+DT H+  SG++IS  +      ++LE     +  S+I + HLND+  E GS  DRH ++  G +   Y
  S:   157 EQIKELFLRIRNTRLKQIGLCIDTAHIWSSGVNISSYNDAGQWLRSLENIHSVIPPSHI-MFHLNDAATECGSGIDRHASLFEGMIWKSY 245
>gi|159041566|ref|YP_001540818.1| xylose isomerase domain-containing protein [Caldivirga maquilingensis IC-167] >gi|157920401|gb|ABW01828.1| Xylose isomerase domain protein TIM barrel [Caldivirga maquilingensis IC-167] (279 aa)
Score = 113, Expect = 8.2e-04, Identities = 48/193 (24%), Positives = 84/193 (43%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND----VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           +HAPY INL S K+ST    + +L+  + R   + + ++V HP            N + +++ + IE    +    V + +E MA +    G+  EE  K+V  + N + + V +D  H++       D    L  + +Y     +   H    K   G   D H+ I      F+ L +    E L ++  I E+P
  S:    67 IHAPYFINLCSDKDSTVEASIKRLMESLERGEAMGATVVVFHPAYYGKLGPEGCYNAVRESVMRVIELMGKEGISHVKLGLEVMARRSQFGGL--EETFKLVKEINNPQVVAV-VDWGHIYARNGGSIDYKAILNMWREYFGNQPMHT-HFTAVKYRRGEWVDEHEPIDTNNPPFEPLAQELAKEDL-DITIICESP 258
>gi|15894910|ref|NP_348259.1| endonuclease IV [Clostridium acetobutylicum ATCC 824] >gi|15024590|gb|AAK79599.1|AE007672_6 Endonuclease IV [Clostridium acetobutylicum ATCC 824] (272 aa)
Score = 113, Expect = 9.3e-04, Identities = 41/141 (29%), Positives = 66/141 (46%)
  Q:    98 HAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYI 238
           H  Y INL + +   +   L +++   +    +  K ++ HPG  L   +    N I +NL K     D  V   +ET  GK ++ G + EE   + S VK  K   +C+D CH+H      +   +T+E+F K   LSY+
  S:    69 HGSYFINLNAEENEKQEASLKRIVSGADALKSVEGKSLIFHPGFYLKDSKEETFNTIKENLKK---LPDIGVDYRLET-TGKPTQFG-SLEENVALASEVKTCK---LCIDFCHLHAR---YNGLFKTIEDFDKV--LSYV 196
>gi|148643311|ref|YP_001273824.1| sugar phosphate isomerase/epimerase [Methanobrevibacter smithii ATCC 35061] >gi|148552328|gb|ABQ87456.1| predicted sugar phosphate isomerase/epimerase, AP endonuclease family 2 [Methanobrevibacter smithii ATCC 35061] (239 aa)
Score = 112, Expect = 9.7e-04, Identities = 47/178 (26%), Positives = 85/178 (47%)
  Q:    95 IVVHAPYL-INLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSA---LDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVK 272
           I +HAP + +N+ S     R   + Q+   ++   +I++  + +HPG      D  R  A+    +++ + ++ +D  +++ VE M  + S +G   EE+ +I    +N+   G+ +D  H +  G          EEF   LDL  I   HLND+       KD+H  +G G +  + L K
  S:    53 IYMHAPTVDLNISSLNTGIRKESVKQMKDALDYGKKINATALTIHPGQIGRNEDRIRKYALELAIESIGELVDYSD--IVVSVENMPERFSFLGNKVEELERI----QNETGCGLTIDVGHGNTCG--------NCEEF---LDLKNISYCHLNDNN----GVKDQHITLGEGTLDLNLLKK 213
>gi|18310061|ref|NP_561995.1| hypothetical protein CPE1079 [Clostridium perfringens str. 13] >gi|18144740|dbj|BAB80785.1| conserved hypothetical protein [Clostridium perfringens str. 13] (236 aa)
Score = 112, Expect = 1.2e-03, Identities = 47/161 (29%), Positives = 74/161 (45%)
  Q:    79 EAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNK-AIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLD-LSYIK 239
           E +   KEKN   L     H  Y INL + +E  +   + +++        +  + +V HPG  L + +  A+  I  NL K   E  D      +ET  GKG++ G N +E+  I   V + K   +C+D  H+H  GI        L+E+  + + L YIK
  S:    17 EKIIEAKEKNDFYLS---AHGSYFINLNAEEEEKKEKSIERILKGAEALKSVGGRSLVFHPGFYLKASKEEALKEIKKNLKKLPYEGVDYR----LET-TGKGTQFG-NLQELVDICKEVPSCK---LCIDFSHIHARGIG------ALKEYKDFAEILEYIK 161
>gi|110802958|ref|YP_698468.1| AP endonuclease [Clostridium perfringens SM101] >gi|110683459|gb|ABG86829.1| AP endonuclease, family 2 protein [Clostridium perfringens SM101] (272 aa)
Score = 111, Expect = 1.3e-03, Identities = 47/161 (29%), Positives = 74/161 (45%)
  Q:    79 EAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNK-AIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLD-LSYIK 239
           E +   KEKN   L     H  Y INL + +E  +   + +++        +  + +V HPG  L + +  A+  I  NL K   E  D      +ET  GKG++ G N +E+  I   V + K   +C+D  H+H  GI        L+E+  + + L YIK
  S:    53 EKIIEAKEKNDFYLS---AHGSYFINLNAEEEEKKEKSIERILKGAEALKSVGGRSLVFHPGFYLKASKEEALKEIKKNLKKLPYEGVDYR----LET-TGKGTQFG-NLQELVDICKEVPSCK---LCIDFSHIHARGIG------ALKEYKDFAEILEYIK 197
>gi|110798659|ref|YP_695781.1| AP endonuclease [Clostridium perfringens ATCC 13124] >gi|110673306|gb|ABG82293.1| AP endonuclease, family 2 [Clostridium perfringens ATCC 13124] (272 aa)
Score = 111, Expect = 1.4e-03, Identities = 46/155 (29%), Positives = 72/155 (46%)
  Q:    85 KEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNK-AIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLD-LSYIK 239
           KEKN   L     H  Y INL + +E  +   + +++        +  + +V HPG  L + +  A+  I  NL K   E  D      +ET  GKG++ G N +E+  I   V + K   +C+D  H+H  GI        L+E+  + + L YIK
  S:    59 KEKNDFYLS---AHGSYFINLNAEEEEKKEKSIERILKGAEALKSVGGRSLVFHPGFYLKASKEEALKEIKKNLKKLPYEGVDYR----LET-TGKGTQFG-NLQELVDICKEVPSCK---LCIDFSHIHARGIG------ALKEYKDFAEILEYIK 197
>gi|89895306|ref|YP_518793.1| hypothetical protein DSY2560 [Desulfitobacterium hafniense Y51] >gi|89334754|dbj|BAE84349.1| hypothetical protein [Desulfitobacterium hafniense Y51] (276 aa)
Score = 110, Expect = 2.1e-03, Identities = 46/159 (28%), Positives = 73/159 (45%)
  Q:    98 HAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATD---NDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH-DSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDR 256
           H PY IN  S +    +    +L+     +  +  K +V HP      D  V +   A  L K  E  D   NDVI+  ET  GK S++G   +EV  +   V     +  C+D  H+H  S   I+  D   Q LE  ++ L   ++K +H + S  + G + ++
  S:    66 HGPYWINFNSQEPEKVAASRERLLHSARISKILGVKSVVFHPAFYHQDDPQVVLVRTAGELMKVREILDAEGNDVILRPET-TGKPSQLG-TLQEVLTLAQAVPG---VLPCIDISHLHARSNGRINTYDEFCQVLEAAAESLGDRWVKHVHFHVSGIDYGVKGEK 226
>gi|109645652|ref|ZP_01369572.1| Xylose isomerase-like TIM barrel [Desulfitobacterium hafniense DCB-2] >gi|109643601|gb|EAT53154.1| Xylose isomerase-like TIM barrel [Desulfitobacterium hafniense DCB-2] (276 aa)
Score = 110, Expect = 2.1e-03, Identities = 46/159 (28%), Positives = 73/159 (45%)
  Q:    98 HAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATD---NDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH-DSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDR 256
           H PY IN  S +    +    +L+     +  +  K +V HP      D  V +   A  L K  E  D   NDVI+  ET  GK S++G   +EV  +   V     +  C+D  H+H  S   I+  D   Q LE  ++ L   ++K +H + S  + G + ++
  S:    66 HGPYWINFNSQEPEKVAASRERLLHSARISKILGVKSVVFHPAFYHQDDPQVVLVRTAGELMKVREILDAEGNDVILRPET-TGKPSQLG-TLQEVLTLAQAVPG---VLPCIDISHLHARSNGRINTYDEFCQVLEAAAESLGDRWVKHVHFHVSGIDYGVKGEK 226
>gi|150401679|ref|YP_001325445.1| xylose isomerase domain-containing protein [Methanococcus aeolicus Nankai-3] >gi|150014382|gb|ABR56833.1| Xylose isomerase domain protein TIM barrel [Methanococcus aeolicus Nankai-3] (264 aa)
Score = 109, Expect = 2.3e-03, Identities = 49/201 (24%), Positives = 93/201 (46%)
  Q:    71 ELDQNLIDEAVKLMKEKNPLLLENIVVHAPYL-INLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADN---LNKAIE-ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLV 271
           E    L  E V+ + E       +IVVHAP+  +N  S  E  R L ++ +   I   +++H+K++ +HPG       N   N I +N   LN  +E A  + V++  E M      +GI  + + +++  + + K +G+  D  H + +      P + ++E +         ++H++   N    + D H  IG G + F  ++
  S:    35 EGSHTLTPENVEYLNELKEHWGVDIVVHAPFSDLNPASMNEKVRKLTIDSIGEAIKGASELHAKVVTIHPGYIPPLWSNYENNIIDNNYLTLNSIVEIAETHAVMLGFENMPNYHGILGITPDSMKEVIKDI-DSKYLGITFDMGHANTA---CGAPHKYIKELNSIGK----GIVHVHCHDNN--EKDDEHLLIGEGNIDFTKVI 230
>gi|15669501|ref|NP_248311.1| hypothetical protein MJ1311 [Methanocaldococcus jannaschii DSM 2661] >gi|2496170|sp|Q58707|Y1311_METJA Uncharacterized protein MJ1311 >gi|1591950|gb|AAB99318.1| conserved hypothetical protein [Methanocaldococcus jannaschii DSM 2661] (293 aa)
Score = 108, Expect = 3.0e-03, Identities = 52/173 (30%), Positives = 85/173 (49%)
  Q:    95 IVVHAPYL-INLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADN----LNKAIE-ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGF 267
           IVVHAP+  +N  S  E  R L +  +   I    ++ S+++V+HPG   +   N  ++ I DN    L++ +E A D  + I +E M      +GI  E + +IV  + + K +G+  D  H + +G    +P     EF + L    I +IH++   N      D H  IG G + F
  S:    75 IVVHAPFSDLNPASMNERVRKLTVECIRDAIEGAFELDSEVVVVHPGYIPELWSNY-VSEILDNNFSTLSEIVEIAEDYGIKIGLENMPNFRGVLGITPESLLEIVKDI-DSKNLGITFDIGHANTAG----NP----AEFVEKLQNIGIGIIHVHAHDNN--GYDDEHLKIGEGNINF 241
>gi|167751485|ref|ZP_02423612.1| hypothetical protein EUBSIR_02481 [Eubacterium siraeum DSM 15702] >gi|167655293|gb|EDR99422.1| hypothetical protein EUBSIR_02481 [Eubacterium siraeum DSM 15702] (281 aa)
Score = 107, Expect = 4.2e-03, Identities = 49/171 (28%), Positives = 82/171 (47%)
  Q:    86 EKNPLLLE--NIVV--HAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND---VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHM----HDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDR 256
           EK P L    NI V  HAPY I+L S +   R   +N +   +   +++ +  +V+H GS     R  A+      L KA+    ++    IIC ETM GK +++G   +EV ++ +       +  C+D  H+    H     I D    L++    L    +  +H++ SK E  +  +R
  S:    51 EKLPALASGNNITVTLHAPYFISLSSVEAEKRDNSVNYIAESLRAADKLGAAKVVVHSGSCAKITRAEALYLAKQTLAKAVALRQSEGLKAIICPETM-GKINQLG-TLDEVLELCT---LDDEMLPCVDFGHLNARTHGEIKTIDDYSAMLDKIENTLGHDRLSQMHIHFSKIEYTNSGER 227
>gi|167948618|ref|ZP_02535692.1| endonuclease IV [Endoriftia persephone 'Hot96_1+Hot96_2'] (90 aa)
Score = 106, Expect = 5.0e-03, Identities = 25/70 (35%), Positives = 38/70 (54%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDS-DRNVAINHIADNLNKAIEA 164
           ++ H  YLINLG P+        N  I EI R  Q+  KL+  HPG+ L   D   ++  +A+++N A+ A
  S:    19 VLPHDSYLINLGHPEPEGLEKSRNAFIDEIQRCQQLGLKLLNFHPGATLRKIDEPASLERVAESINIALGA 89
>gi|154500711|ref|ZP_02038749.1| hypothetical protein BACCAP_04384 [Bacteroides capillosus ATCC 29799] >gi|150270600|gb|EDM97909.1| hypothetical protein BACCAP_04384 [Bacteroides capillosus ATCC 29799] (282 aa)
Score = 106, Expect = 5.1e-03, Identities = 30/117 (25%), Positives = 62/117 (52%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND----VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH 213
           +HAPY INL +P   +       +I      + + +  +V+H G+ +   R  A +   ++L + + A D +    + +C ETM GK +++G + +EV ++ +     +R+  C+D  H++
  S:    65 LHAPYFINLANPDPESLKKTTGYIIAACRAADWMGATRVVIHSGALMKRTRREAQDIALNSLKEIVAAVDGEGFGHITLCPETM-GKINQLG-DLDEVLELCT---LDERLTPCIDFGHLY 180
>gi|159905379|ref|YP_001549041.1| xylose isomerase domain-containing protein [Methanococcus maripaludis C6] >gi|159886872|gb|ABX01809.1| Xylose isomerase domain protein TIM barrel [Methanococcus maripaludis C6] (273 aa)
Score = 105, Expect = 6.7e-03, Identities = 49/173 (28%), Positives = 88/173 (50%)
  Q:    80 AVKLMKEKNPLLLENIVV----HAPYLINLGSP-----KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVI--ICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGI-DISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGS 252
            V L  EK  +L +N+ +    HAPY INL +      + S + +  +  I+ I       +K +V H G  L  D+++    I  N+ K +E  D + I  I      GKG++ G + +E+ ++ + ++    I  C+D  H++   +  I+D D     L +  + L    IK +H++ S  E G+
  S:    38 GVNLKSEKAEILAKNLEITLSAHAPYYINLNAKEPEKIESSIKRIVDSAKIIHIFNKKNSENKNVVFHSGFYLKQDKDLVYEKIKANIQKILEIMDENKINAILRPETTGKGTQFG-SIDELIQLSTEIE----IMPCIDFSHVYARSLGKINDYDSFSNILSKLEENLGKKGIKDMHIHISGIEFGN 220
>gi|45358184|ref|NP_987741.1| xylose isomerase domain protein TIM barrel [Methanococcus maripaludis S2] >gi|44920941|emb|CAF30177.1| conserved hypothetical archaeal protein [Methanococcus maripaludis S2] (269 aa)
Score = 103, Expect = 1.3e-02, Identities = 45/178 (25%), Positives = 84/178 (47%)
  Q:    41 YLVGSVLETLEYDGNCFMVFTGPPQNFMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYL-INLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPG----SALDSDRNVAINHIADNLNKAIE-ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID 218
           Y +G +++     G   M F      F +K  D + I+        K  L   ++ +HAPY+ +N  S  E+ R + L +    I+ + +  S+L+ +HPG    + + +D     N+  D L K+I  A  N++ +C+E    K + +  N E + K +   +N   + + LD  H  ++  D
  S:    14 YDIGEIVDIFLEIGLKNMEFFPENPEFWKKRNDLDYINNV------KTELSKLDVTIHAPYIELNSSSTNENIRLVTLMETFWAIDLSKKFKSELLTIHPGKRPTARIPTDEEY--NNFDDYLEKSINYALKNEITLCLENSPKKINNICYNVESMKKTLDKFEN---LYMTLDIAHARENSRD 186
>gi|146297237|ref|YP_001181008.1| xylose isomerase domain-containing protein [Caldicellulosiruptor saccharolyticus DSM 8903] >gi|145410813|gb|ABP67817.1| Endonuclease IV [Caldicellulosiruptor saccharolyticus DSM 8903] (286 aa)
Score = 103, Expect = 1.4e-02, Identities = 28/90 (31%), Positives = 44/90 (48%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAI----NHIADNLNKAIEATDNDVIICVETMAGKGSEVG 184
           + +HAPY IN GS +E         +   +    ++ ++ IV HPGS    DR +A       I + +N   E     + +C ETM GK + +G
  S:    65 VSIHAPYYINFGSQEEEKLQKSKEYIYECVEVAKEMRAERIVFHPGSCAKVDRKIAFETAKKAILEVVNVVREMKVEGIFLCPETM-GKKNNLG 157
>gi|9631347|ref|NP_048188.1| ORF MSV117 putative DNA polymerase beta/AP endonuclease, similar to Rattus norvegicus GB:M13962 and Caenorhabditis elegans GB:Z47812 [Melanoplus sanguinipes entomopoxvirus] >gi|4049700|gb|AAC97660.1| ORF MSV117 putative DNA polymerase beta/AP endonuclease, similar to Rattus norvegicus GB:M13962 and Caenorhabditis elegans GB:Z47812 [Melanoplus sanguinipes entomopoxvirus] (603 aa)
Score = 102, Expect = 1.7e-02, Identities = 56/193 (29%), Positives = 97/193 (50%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATD-------NDVIICVETMAGKGSEVGINFEEVSKIVSGVKN--KKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKY---LDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWA--HNEKL----ANVPKILE 287
           I +H+ Y+ N+ + K       L + IV ++  N ++    + H    +DS +  +IN I  +L K     D       N VII    +      +G   E+++ I + + +  K R+  C+DT H+ ++   I+     ++   K+   + L+ +  IHLNDS+    S    H +I  GK+ +DY  K +  H  KL     N+P ILE
  S:    48 IFIHSKYVGNIANSKSHVTISNLKKEIVYLDTLN-VNKCGSIFHLTKIVDS-KEKSINTIVSSLEKLSSKLDSLNLNTFNYVIIETSNIV---DHIGSTIEDLALIYNKLSSHTKNRVRFCIDTAHIFNTYYAINTVKGIVDYLIKFDVLIGLNKVVAIHLNDSEGMPLSSIRPHISITEGKIFYDYKSKLSPLHIIKLFSLYYNIPCILE 253
>gi|150402875|ref|YP_001330169.1| xylose isomerase domain-containing protein [Methanococcus maripaludis C7] >gi|150033905|gb|ABR66018.1| Xylose isomerase domain protein TIM barrel [Methanococcus maripaludis C7] (273 aa)
Score = 101, Expect = 2.1e-02, Identities = 50/173 (28%), Positives = 85/173 (49%)
  Q:    80 AVKLMKEKNPLLLENIVV----HAPYLINLGSP-----KESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVI--ICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGI-DISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGS 252
            V L  EK  LL +N+ +    HAPY INL +      + S + +  +  I+ I       +K +V H G  L  D+ +    I  N  + IE  D + I  +      GKGS+ G + +E+ ++ + ++    I  C+D  H++   +  I+D D     L +    L    IK +H++ S  E G+
  S:    38 GVNLKSEKAELLAKNLEITLSAHAPYYINLNAKEPEKIESSIKRIVDSAKIIHIFNKKNSENKNVVFHSGFYLKQDQKLVYEKIKANTQRIIEIMDENKINAMLRPETTGKGSQFG-SVDELIQLSTEIE----IMPCIDFSHVYARSLGKINDYDSFSNILSKLENNLGKKGIKDMHIHISGIEFGN 220
>gi|156937880|ref|YP_001435676.1| endonuclease IV [Ignicoccus hospitalis KIN4/I] >gi|156566864|gb|ABU82269.1| Endonuclease IV [Ignicoccus hospitalis KIN4/I] (283 aa)
Score = 100, Expect = 2.4e-02, Identities = 35/134 (26%), Positives = 59/134 (44%)
  Q:    79 EAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDN---DVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHM 212
           EA K+ +E + +L      HAPY +NL SP+E  R   +  ++      +      +V HPG  +    +V    I D L + +E       DV I  ETM     E+   F  + +++   +    +  C+D  H+
  S:    56 EAGKVARELDVVL----TAHAPYYVNLASPEEEKRKRSIEYIVQSAKVLHAAGGWSVVFHPGWYMKKAPSVVYKRIRDALAEVVERVKELGLDVWIRPETM-----ELKSKFGSLDEVIKLSQEFDIVLPCVDFAHL 183
>gi|52549021|gb|AAU82870.1| conserved hypothetical protein [uncultured archaeon GZfos21B5] (263 aa)
Score = 100, Expect = 2.7e-02, Identities = 52/187 (27%), Positives = 90/187 (48%)
  Q:    79 EAVKLMKEKNPLLLENIVVHAPYL-INLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIE--------ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKV 265
           E V+ + E   L+     +H+P   IN+ S  E  R   + Q+   I+   +  + + V+HPG    S   V +   A    KAI         A +  + I +E +      +G + EE+++IV GV N   +G+CLD  H        ++  +TL+EF      + +++IH++ S N  G+  D H  +G G +
  S:    47 ERVRELSETTNLIFS---LHSPLSDINIASVNERMREESIRQIEECIDAAYEFIADICVVHPG--FLSPLTVQMPEKA--FQKAIASLTTICDFAAERGLRIALENLTSAKMLMGRDPEELNRIVRGV-NADNLGLCLDVAH--------ANTTKTLDEFLNK-KATAVEIIHMHASDN-FGA-DDLHLPLGEGNL 223
>gi|134298360|ref|YP_001111856.1| xylose isomerase domain-containing protein [Desulfotomaculum reducens MI-1] >gi|134051060|gb|ABO49031.1| Endonuclease IV [Desulfotomaculum reducens MI-1] (284 aa)
Score = 97, Expect = 6.9e-02, Identities = 42/171 (24%), Positives = 85/171 (49%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQ-IHSKLIVLHPGSALDSDRNVAINH----IADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGF 267
           +HAPY INL S +ES + +     I++  R  + + +K +V HPG    ++R    N       + L +       D+++  ETM GK +++G + EEV ++ S     +++  C+D  H++          +T ++++K LD+           +N++G    +H ++ +  + F
  S:    68 IHAPYYINL-STEESDKKIKTKGYILDSLRVARWMEAKTVVFHPGGGPGTNRGETFNRSKILFREILQEIAAEGLQDILLAPETM-GKINQMG-SLEEVLELCS---LGEQVVPCIDFGHLNAVS---QGSLKTKDDYAKILDI----------IENQLGKEVVKHLHVHFSIIEF 224
>gi|150400560|ref|YP_001324326.1| xylose isomerase domain-containing protein [Methanococcus aeolicus Nankai-3] >gi|150013263|gb|ABR55714.1| Xylose isomerase domain protein TIM barrel [Methanococcus aeolicus Nankai-3] (254 aa)
Score = 96, Expect = 7.0e-02, Identities = 54/202 (26%), Positives = 96/202 (47%)
  Q:    66 NFMRKELD--QNLIDEAVKLMKEKNPLLLENI----VVHAPYL-INLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPG-SALDSDRNVAINHIADNLNKA-IEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGF 267
           +F+ K+++  + + D  + +M++KN  +  N      +H P   I+L S +E  R   ++ +   I   N++ +KLIVLHPG +    D + ++N +  +LN   +   +  + I +E M          F   S I   + N   +G+  D  H        S  +  +EEF     +  I  IH++D+ +E     D H  IG GK+ F
  S:    22 DFLEKKVNFVELVCDGNINIMEQKNIDISYNYDLNYTIHCPLTDISLSSYREKVRKFSISYVKDIIKVANKVDAKLIVLHPGHNIFKYDYDKSLNSLIKSLNDLNMLQNEYGIKITIENMPSYDM-----FMFRSPIEEIISNLGDLGITFDVGH--------SFLNNNIEEFLDKNIVDKISHIHIHDNNSEY----DEHLCIGDGKIDF 215
>gi|73669829|ref|YP_305844.1| endonuclease IV [Methanosarcina barkeri str. Fusaro] >gi|72396991|gb|AAZ71264.1| Endonuclease IV [Methanosarcina barkeri str. Fusaro] (279 aa)
Score = 96, Expect = 8.0e-02, Identities = 54/207 (26%), Positives = 92/207 (44%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICV---ETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH---DSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSR-KDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEIIN 303
           VHAPY INL S +E      L ++       +   ++ I+LH G    S +      I+  L +       + I  V   ETM GK ++ G   EEV  + + ++    +  CLD CH+H         S+  + L    + L    +  +H++ S  E G+  + RH  +    + +  L+K A  E  A    ILE+P  ++  +  + + N
  S:    68 VHAPYYINLNSYEEKKLKASLERIYNAAKIGSLCGAESIILHAGFYQKSSKKSTFESISKALKELTGQFREEGIPAVLRPETM-GKRTQFG-TLEEVLALSAEIEG---VMPCLDFCHLHAREGKENSYSEFTEILSRVEESLGKEGLSNMHMHVSGVEYGTNGEKRHLALKESDLNYPELMK-ALKEFKARGRVILESPILEEDALMLRMLYN 275
>gi|20092355|ref|NP_618430.1| hypothetical protein MA3548 [Methanosarcina acetivorans C2A] >gi|19917604|gb|AAM06910.1| conserved hypothetical protein [Methanosarcina acetivorans C2A] (277 aa)
Score = 96, Expect = 8.5e-02, Identities = 37/121 (30%), Positives = 58/121 (47%)
  Q:    93 ENIV--VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICV---ETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH 213
           ENI   VHAPY INL SP+E      + ++       +   ++ IVLH      S++     +++  L +  E    + I  V   ETM GK ++ G   EEV  +   ++    +  CLD  H+H
  S:    62 ENIALSVHAPYYINLNSPEEEKLQASMERIYQAARIGSLCGAESIVLHAAFYQKSNKQAVYENVSKALGELAEQLQAENIPAVLRPETM-GKRTQFG-TLEEVLALSEEIEG---VMPCLDFSHIH 182
>gi|148643023|ref|YP_001273536.1| endonuclease IV [Methanobrevibacter smithii ATCC 35061] >gi|148552040|gb|ABQ87168.1| endonuclease IV, xylose isomerase-like TIM barrel family, Nfo [Methanobrevibacter smithii ATCC 35061] (278 aa)
Score = 96, Expect = 8.7e-02, Identities = 57/224 (25%), Positives = 97/224 (43%)
  Q:    78 DEAVKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI---EATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLE-EFSKYLDLSYIKVIHLNDSKNEIGSRKD-RHDNIG----YGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEI 301
           +++ K++KE++      I +H PY INL S +E      LN LI        + +  +V HPG   +     A+    + +N+     EA   +         GK S+ G     VS+I+    +       +D  H+H  G    +  +     FS+  D   I ++H + +  E G+  + +H  +     YG    D L     N   AN+  I ETP RD+  +  +E+
  S:    47 EKSAKILKEESEKHDILISMHGPYYINLCSKEEEKIKKSLNHLIATARAGEWMGAYRLVFHPGFYSNRKPGKAMEISKNTINQLFEELEAEGIEEFTFAPETTGKRSQQG----NVSEIIELCASFDHFEPTVDFAHVHARGRGFLNKKEDYNCIFSQLEDNLDIDILHCHFTTIEYGNGGEVKHHTLAESNEYGPDIKDLLANLIDNGWRANI--ICETPLRDEDALKMKEL 273
>gi|450734|emb|CAA50842.1| unnamed protein product [African swine fever virus] (229 aa)
Score = 95, Expect = 1.1e-01, Identities = 53/175 (30%), Positives = 92/175 (52%)
  Q:    78 DEAVKLMK--EKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIV-EINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGIN-FEEVSKIVSGVKNK--KRIGVCLDTCHMHDSGIDISDPD------QTLEEFSKYLDLSYIKVIHLNDSKNEIGS 252
           D+ V+L+K  +K+ L    +V H  YL        S RS  +   I  E+    ++  K +VLH G+       V    I + L K I+  +  VII +ET   K      +  E++ ++   ++N   K+IG+C+DT H+  SG++IS  +      ++LE+    +  S+I + HLND+  + G+
  S:    59 DDKVELLKMIDKHNLW---VVAHGTYL----DVPWSRRSAFVTHFIQQELLICKEVGIKGLVLHLGA-------VEPELIVEGLKK-IKPVEG-VIIYLETPHNKHHTYKYSTIEQIKELFLRIRNTGLKQIGLCIDTAHIWSSGVNISSYNSARQWLRSLEDIHSVIPPSHI-MFHLNDAATKCGT 228
>gi|91773493|ref|YP_566185.1| xylose isomerase-like TIM barrel [Methanococcoides burtonii DSM 6242] >gi|91712508|gb|ABE52435.1| Xylose isomerase-like TIM barrel [Methanococcoides burtonii DSM 6242] (269 aa)
Score = 94, Expect = 1.3e-01, Identities = 40/148 (27%), Positives = 71/148 (47%)
  Q:   124 INRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNK-AIEATDNDVIICVETM-AGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLV 271
           I    ++ +K +V+HPG   D DR  ++  +  NL + A  A++N+V++ +E   A     +    EE+ K+V+ V +   +GV  D  H   + +      + L EF + +    I V HL+D+     S  D  +++  G    DY V
  S:    92 IELAGKLETKAVVIHPGRVGD-DRQRSLGRMTTNLKRLAAFASENNVMLGLENKEATDPGNLCCEAEELLKVVNEV-DSSNLGVTFDIGH---ANLTCGGDHEKLNEFIRTVSEQVIHV-HLHDNYGTWTSNYDGDEHMAPGTGTIDYSV 235
>gi|169842075|ref|ZP_02875180.1| hypothetical protein cdivTM_33232 [candidate division TM7 single-cell isolate TM7a] (36 aa)
Score = 94, Expect = 1.4e-01, Identities = 17/29 (58%), Positives = 23/29 (79%)
  Q:   262 YGKVGFDYLVKWAHNEKLANVPKILETPY 290
           +G +GF+ L K AH EK +++PKILETPY
  S:     1 FGYIGFEVLNKIAHFEKFSHLPKILETPY 29
>gi|153954037|ref|YP_001394802.1| hypothetical protein CKL_1412 [Clostridium kluyveri DSM 555] >gi|146346918|gb|EDK33454.1| Hypothetical protein CKL_1412 [Clostridium kluyveri DSM 555] (272 aa)
Score = 94, Expect = 1.4e-01, Identities = 33/116 (28%), Positives = 58/116 (50%)
  Q:    98 HAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH 213
           H  Y INL + +E  +   L ++I   +  ++I  + +V HPG  L   +    + I +NL   ++    +V   +ET  GKGS+ G + EE+  +   V + K   +C+D  H+H
  S:    69 HGSYFINLNADEEKKQLKSLERIIKGASALSKIQGRSLVFHPGFYLKDSKEDTYDTIKENL---LKLPHENVDYRLET-TGKGSQFG-SLEELVFLCLEVPSCK---LCIDFAHIH 176
>gi|15668303|ref|NP_247099.1| hypothetical protein MJ0133 [Methanocaldococcus jannaschii DSM 2661] >gi|2495820|sp|Q57597|Y133_METJA Uncharacterized protein MJ0133 >gi|1498901|gb|AAB98114.1| conserved hypothetical protein [Methanocaldococcus jannaschii DSM 2661] (273 aa)
Score = 93, Expect = 1.9e-01, Identities = 45/159 (28%), Positives = 77/159 (48%)
  Q:    98 HAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNK---AIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH--DSGI--DISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDR 256
           HAP+ INL + +E      + ++I      N    K +V HPG  L   + V  N I  N+ +    +EA + +V++  ET  GK ++ G + +E  K+   +     I  C+D  H++    G+  D +   + LE+    L    IK +H++ S  E G   +R
  S:    66 HAPHYINLNANEEEKVENSIRRIIKTAKVLNNC-GKNLVFHPGYYLKRSKEVTYNRIKSNIQRILDKLEALNLNVMLRPET-TGKTTQFG-DIDETLKLCFELN----ILPCIDFSHIYARSRGVINDYNSFYKILEKVENVLGKEAIKDMHIHLSGIEYGKGGER 224
>gi|21226562|ref|NP_632484.1| putative endonuclease IV [Methanosarcina mazei Go1] >gi|20904835|gb|AAM30156.1| putative endonuclease IV [Methanosarcina mazei Go1] (277 aa)
Score = 92, Expect = 2.3e-01, Identities = 34/121 (28%), Positives = 59/121 (48%)
  Q:    93 ENIV--VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNK---AIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH 213
           ENI   VHAPY INL S +E      + ++       +   ++ IVLH      S R  A  +++  L++    +     D ++  ETM GK ++ G     + +++S  +  + +  CLD  H+H
  S:    62 ENIALSVHAPYYINLNSSEEEKLKASMERIYQAARIGSLCGAESIVLHAAFYQKSSREAAYQNVSKALSELAGRLRGESIDAVLRPETM-GKRAQFGT----LDEVLSLSEEIEGVMPCLDFSHLH 182
>gi|121535178|ref|ZP_01666994.1| Xylose isomerase domain protein TIM barrel [Thermosinus carboxydivorans Nor1] >gi|121306287|gb|EAX47213.1| Xylose isomerase domain protein TIM barrel [Thermosinus carboxydivorans Nor1] (285 aa)
Score = 92, Expect = 2.4e-01, Identities = 38/138 (27%), Positives = 64/138 (46%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINH----IADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHD-SGIDISDPDQTLEEFSKYLD 234
           +HAPY INL +      +     L+  +     + +  +V HPG     +R  A+       A+ L +A     N V++  ETM GK +++G   +EV ++    +  K +   +D  HMH  +G   +    T EEF+   D
  S:    68 IHAPYYINLATEDAKIAANTKKHLLKSLEAAQWMGADRVVFHPGGPGRQERRRAMEQAKRLFAEVLAEAERQGLNTVLLAPETM-GKQNQLG-TLDEVLEL---CRMAKWVAPAVDFGHMHAVTGGQYT----TREEFAAVFD 201
>gi|146303512|ref|YP_001190828.1| endonuclease IV [Metallosphaera sedula DSM 5348] >gi|145701762|gb|ABP94904.1| Endonuclease IV [Metallosphaera sedula DSM 5348] (276 aa)
Score = 92, Expect = 2.6e-01, Identities = 47/193 (24%), Positives = 84/193 (43%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNL----NKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETP 289
           VHAPY INL S  +        +++    R + + +  I +H G   D       + + D+L    +K  E + + V + VETMA + +     F  + +++S  K    +   +D  H         D D+ L+  ++ L L++I   H    +   G   D H+ I      F+ L K A  ++  ++  I E+P
  S:    66 VHAPYFINLCSSDQEKVMASQKRILDTAERASAMGADAIAIHVGFYGDYTPEQCYSLVKDSLLVVRDKMKENSIDSVKLGVETMAKETA-----FGTLDEVISISKEVPGVIPYIDWAHTFARQGGNIDYDEILDRLTRELGLTHINS-HFESLQVRKGKYVDVHEPISKNAPPFEPLAK-ALLKRDISITLICESP 255
>gi|41614874|ref|NP_963372.1| hypothetical protein NEQ077a [Nanoarchaeum equitans Kin4-M] >gi|40068598|gb|AAR38933.1| NEQ077a [Nanoarchaeum equitans Kin4-M] (269 aa)
Score = 91, Expect = 2.7e-01, Identities = 47/180 (26%), Positives = 84/180 (46%)
  Q:    81 VKLMKEKNPLLLENIVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDND---VIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGV--CLDTCHMHDSGIDISDPD---QTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNI 260
           VK   +KN ++L     HAPY INL + ++      +  ++      N+++   IV HPG  +  D       + +NL K +E  + +   V I  ETM    S  G + EE  ++       + +G   C+D  H+     + + P+   Q LE++ +Y     +K +H++ S   +  R   H N+
  S:    53 VKEFAQKNNIVL---TAHAPYYINLAAKEKEKIEKSIKYILDTARVLNELNGYSIVFHPGYYMKRDPKEVYKIVKENLAKVLEMANQEGIKVWIRPETM-DLPSRFG-SLEETFELA------RELGTLPCIDFAHLRYRYKN-NKPEFFRQVLEKYEEYFGKEGLKNMHIHMSGINLDPRAS-HKNL 227
>gi|9964524|ref|NP_064992.1| putative DNA polymerase beta/AP endonuclease [Amsacta moorei entomopoxvirus] >gi|9944733|gb|AAG02916.1|AF250284_210 AMV210 [Amsacta moorei entomopoxvirus] (612 aa)
Score = 91, Expect = 2.7e-01, Identities = 52/193 (26%), Positives = 93/193 (48%)
  Q:    95 IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVI------ICVETMAGKGSEVGINFEEVSKIVSGVKN--KKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKY---LDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDY------LVKWAHNEKLANVPKILE 287
           I VH+ Y+ N+   K S     + + ++ +    +I++   V+H     + ++  ++ ++A+ LNK  +  DN +       I  ET       +G   E+   +   + +  KKRI  C+DT H+  +  +I+     +   +K+   + L  I +IHLNDS     S    H+ IG G +  +Y      L        L N+P ILE
  S:    56 IFVHSKYVGNIAKDKNSVALRNIKKELLYLQNM-EINNSGTVVHLSLYYNKNQEESLKYVANELNKFCKVLDNILDNNYFNHIIFET-TNDIRHLGAKTEDFKILYDNLDSNAKKRIKFCIDTSHIFVTFYNINTVKGMINYLAKFDLLIGLDKIILIHLNDSCGLPLSSYKPHEAIGKGNIFKNYKDDLSSLHILKTYATLYNIPCILE 263
>gi|42783411|ref|NP_980658.1| endonuclease, putative [Bacillus cereus ATCC 10987] >gi|42739340|gb|AAS43266.1| endonuclease, putative [Bacillus cereus ATCC 10987] (48 aa)
Score = 91, Expect = 2.8e-01, Identities = 16/45 (35%), Positives = 24/45 (53%)
  Q:    28 LLLGSHVGFKAKNYLVGSVLETLEYDGNCFMVFTGPPQNFMRKEL 72
           L +GSHV    K  L+ +  E + Y    FM++TG P  + R +L
  S:     2 LKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPXKYRRNQL 46
>gi|150403559|ref|YP_001330853.1| xylose isomerase domain-containing protein [Methanococcus maripaludis C7] >gi|150034589|gb|ABR66702.1| Xylose isomerase domain protein TIM barrel [Methanococcus maripaludis C7] (269 aa)
Score = 91, Expect = 3.4e-01, Identities = 32/125 (25%), Positives = 64/125 (51%)
  Q:    94 NIVVHAPYL-INLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVA--INHIADNLNKAIE-ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID 218
           +I +HAPY+ +N  S  E+ R + L +    ++ + + ++KLI +H G    +    A    +  D L K+I  A  N++ +C+E    K + +  + E + K +    N K + + LD  H  ++ ++
  S:    61 DITIHAPYIELNPSSTNENIRCVTLMETFWAMDLSKKFNAKLITIHAGKRPTNRIPTAEEYTNFDDYLEKSINYALKNEITLCLENSPKKINNICYSVESMKKTLD---NFKSLYMTLDIAHARENSLE 186
>gi|118443842|ref|YP_878390.1| endonuclease IV [Clostridium novyi NT] >gi|118134298|gb|ABK61342.1| endonuclease IV [Clostridium novyi NT] (272 aa)
Score = 90, Expect = 3.5e-01, Identities = 38/129 (29%), Positives = 60/129 (46%)
  Q:    85 KEKNPLL---LEN---IVVHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAIEATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMH 213
           K KN +L   L+N   +  H  Y INL + +E      L ++I       ++  K ++ HPG  L   +      I +NL   +   D  V   +ET  GKG++ G + EE   +   V   K   +C+D  H+H
  S:    50 KNKNEVLDTKLKNDFYLSAHGSYFINLNADEEEKIEKSLERIIKGAEGLKKVQGKSLIFHPGFYLKDSKEETFETIKENL---LRLPDLGVDYRLET-TGKGTQFG-SLEENVALCKAVDTCK---LCIDFSHIH 176
>gi|126460386|ref|YP_001056664.1| endonuclease IV [Pyrobaculum calidifontis JCM 11548] >gi|126250107|gb|ABO09198.1| Endonuclease IV [Pyrobaculum calidifontis JCM 11548] (275 aa)
Score = 90, Expect = 3.6e-01, Identities = 46/206 (22%), Positives = 85/206 (41%)
  Q:    97 VHAPYLINLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLHPGSALDSDRNVAINHIADNLNKAI-EATD-NDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGIDISDPDQTLEEFSKYLDLSYIKVIHLNDSKNEIGSRKDRHDNIGYGKVGFDYLVKWAHNEKLANVPKILETPYRDDKPIYKQEII 302
           VHAPY INL S +         +L+  ++R   + + ++V+H         +     + + L KA  EA + + V I VE  A K       F  V +  S  K    +   +D  H++       D    L+ +++     ++   H    +   G   D H+ +  G+  F+ L K      +A +  I E+P  D   ++ +E++
  S:    67 VHAPYFINLCSDEADKVEKSRQRLVDSLDRAYHMGAWVVVVHAAYYGKLGPSGCYEKVREELAKAYREAGEPSGVYIGVEITARKN-----QFGSVEEAFSLAKELTFVTPVIDWGHLYARNNGTIDYGAVLDLWNREFPGRHMHT-HFTSVRYRNGKFVDEHEPVEVGRPPFEPLAKQLAERDMA-ITLICESPLLDKDALFMKEVL 267
>gi|134046019|ref|YP_001097505.1| xylose isomerase domain-containing protein [Methanococcus maripaludis C5] >gi|132663644|gb|ABO35290.1| Xylose isomerase domain protein TIM barrel [Methanococcus maripaludis C5] (269 aa)
Score = 89, Expect = 4.6e-01, Identities = 40/155 (25%), Positives = 78/155 (50%)
  Q:    64 PQN--FMRKELDQNLIDEAVKLMKEKNPLLLENIVVHAPYL-INLGSPKESTRSLGLNQLIVEINRTNQIHSKLIVLH----PGSALDSDRNVAINHIADNLNKAIE-ATDNDVIICVETMAGKGSEVGINFEEVSKIVSGVKNKKRIGVCLDTCHMHDSGID 218
           P+N  F +K  D + I+        K+ L    I +H+PY+ +N  S  E+ R + L +    I+ + + ++KLI +H    P   + +D     ++  D L K+IE A   ++ +C+E    K + +  N E + K +   ++   + + LD  H  ++ +D
  S:    35 PENPEFWKKRNDLDYINSV------KSELSKLEITIHSPYIELNSSSTNENIRYVTLMETFWAIDLSKKFNAKLITIHAGKRPTHRVPTDEEY--DNFDDYLKKSIEYALKKEITLCLENSPEKINNICYNVESMKKTLYKFED---LYITLDIAHARENSLD 186