CyclinA-cyclin-dependent kinase2 (CDK2)-ATP complex

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The binary complex of phosphorylase kinase complexed with Mg2+/ADP has been solved to a resolution of 3.0 A. The structures were solved by molecular replacement using the cAMP-dependent protein kinase (cAPK) as a model


[1] Jeffrey PD; Russo AA; Polyak K; Gibbs E; Hurwitz J; Massague J; Pavletich NP (1995) Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex. Nature 376: 313-20. [

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Sequence Information

Last modified Wednesday, 30 July 1997 by Phil Bourne