Snapshot - 1FMK

MOL_ID: 1; MOLECULE: TYROSINE-PROTEIN KINASE SRC; CHAIN: NULL; FRAGMENT: RESIDUES 86-836, CONTAINING SH2, SH3, KINASE 2 DOMAINS AND C-TERMINAL TAIL; SYNONYM: C-SRC, P60-SRC; EC: 2.7.1.112; ENGINEERED: YES

Compound summary followed by details of each entity.

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      Resolution: 1.50 Å                        Deposition Date: 24-JAN-97

      Source: MOL_ID: 1; ORGANISM_SCIENTIFIC: HOMO SAPIENS; 
              ORGANISM_COMMON: HUMAN; EXPRESSION_SYSTEM: 
              BACULOVIRUS/INSECT CELL 
              
      Functional Class: PHOSPHOTRANSFERASE                      

      Authors: W.XU,S.C.HARRISON,M.J.ECK 
               
      Primary Citation: W.XU,S.C.HARRISON,M.J.ECK THREE-DIMENSIONAL 
                        STRUCTURE OF THE TYROSINE KINASE C-SRC NATURE V. 
                        385 595 1997 ASTM NATUAS UK ISSN 0028-0836 0006 
                        
      Number of Entities: 1

Entity 1FMK:_

      Type: Protein                  Molecular Weight: 59512
      Number of Residues: 452
      Number of Alpha: 10            Content of Alpha: 24.78
      Number of Beta: 21             Content of Beta: 21.02

      Secondary structure by segment:

     LELELELELELHLELELELELELHLELELELELELELHLELELEHLHLELELHLHLHLHL
     HL

      Sequence and secondary structure:

   1 MVTTFVALYD YESRTETDLS FKKGERLQIV NNTEGDWWLA HSLSTGQTGY 
       EEEEESS  B   SSSB   BTTTTEEEES    SSSEEEE EETTTT EEE 

  51 IPSNYVAPSD SIQAEEWYFG KITRRESERL LLNAENPRGT FLVRESETTK 
     EEGGGEEEGG GGGGGGGBGB GTTHHHHHHH HGGGGGGGGE EEEEE SSTT 

 101 GAYCLSVSDF DNAKGLNVKH YKIRKLDSGG FYITSRTQFN SLQQLVAYYS 
     TTEEEEEEEE ETTTEEEEEE EEEEEETTTE EESTTTTEES THHHHHHHHH 

 151 KHADGLCHRL TTVCPTSKPQ TQGLAKDAWE IPRESLRLEV KLGQGCFGEV 
     HTTTTTSS    EE         SSSTTTTSB  TGGGEEE E E EE SS EE 

 201 WMGTWNGTTR VAIKTLKPGT MSPEAFLQEA QVMKKLRHEK LVQLYAVVSE 
     EEEEETTTEE EEEEEETTTT STHHHHHHHH HHHHHT TTT B  B EEE S 

 251 EPIYIVTEYM SKGSLLDFLK GETGKYLRLP QLVDMAAQIA SGMAYVERMN 
     SSEEEEE  T TTEEHHHHHH HHHHGGTTHH HHHHHHHHHH HHHHHHHHTT 

 301 YVHRDLRAAN ILVGENLVCK VADFGLARLI EDNEYTARQG AKFPIKWTAP 
     T  S  TGGG EEETGGGTEE E   TTTT                 TGGGGGH 

 351 EAALYGRFTI KSDVWSFGIL LTELTTKGRV PYPGMVNREV LDQVERGYRM 
     HHHHHT  TH HHHHHHHHHH HHHHHGGGT  STTTTTHHHH HHHHHHTT   

 401 PCPPECPESL HDLMCQCWRK EPEERPTFEY LQAFLEDYFT STEPQ*QPGE 
       TGGGGHHH HHHHHHHTTS TGGGT THHH HHHHHHGGGT  S      S  

 451 NL