Snapshot - 1P38

MOL_ID: 1; MOLECULE: MAP KINASE P38; CHAIN: NULL; SYNONYM: MITOGEN ACTIVATED PROTEIN KINASE; EC: 2.7.1.-; ENGINEERED: YES; MUTATION: 19 RESIDUES INSERTED AT N-TERMINUS

Compound summary followed by details of each entity.

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      Resolution: 2.10 Å                        Deposition Date: 06-JAN-97

      Source: MOL_ID: 1; ORGANISM_SCIENTIFIC: MUS MUSCULUS; 
              ORGANISM_COMMON: MOUSE; EXPRESSION_SYSTEM: 
              ESCHERICHIA COLI; EXPRESSION_SYSTEM_STRAIN: BL21 
              (DE3); EXPRESSION_SYSTEM_PLASMID: PET14B 
              
      Functional Class: TRANSFERASE                             

      Authors: Z.WANG,P.C.HARKINS,R.J.ULEVITCH,J.HAN,M.H.COBB,E.J.
               GOLDSMITH 
               
      Primary Citation: Z.WANG,P.C.HARKINS,R.J.ULEVITCH,J.HAN,M.H.COBB, 
                        E.J.GOLDSMITH THE STRUCTURE OF MITOGEN-ACTIVATED 
                        PROTEIN KINASE P38 AT 2.1-A RESOLUTION 
                        PROC.NAT.ACAD.SCI.USA V. 94 2327 1997 ASTM PNASA6 
                        US ISSN 0027-8424 0040 
                        
      Number of Entities: 1

Entity 1P38:_

      Type: Protein                  Molecular Weight: 50128
      Number of Residues: 379
      Number of Alpha: 12            Content of Alpha: 32.19
      Number of Beta: 10             Content of Beta: 11.87

      Secondary structure by segment:

     LELELELELELELHLELELHLHLELELHLHLHLHLHLHLHLHLHL

      Sequence and secondary structure:

   1 GSSHHHHHHS SGLVPRGSHM SQERPTFYRQ ELNKTIWEVP ERYQNLSPVG 
                                 EEEE EETTEEEEEE TTEES EE B 

  51 SGAYGSVCAA FDTKTGHRVA VKKLSRPFQS IIHAKRTYRE LRLLKHMKHE 
       SSEEEEEE EETTTT EEE EEEESTTTTT HHHHHHHHHH HHHHHHT TT 

 101 NVIGLLDVFT PARSLEEFND VYLVTHLMGA DLNNIVKCQK LTDDHVQFLI 
     TB   SEEE    SSTTTT    EEEEE     BHHHHHHHT   THHHHHHHH 

 151 YQILRGLKYI HSADIIHRDL KPSNLAVNED CELKILDFGL ARHTDDEMTG 
     HHHHHHHHHH HHTTT      TGGGEEETTT T EEE    S S   SSSSSS 

 201 YVATRWYRAP EIMLNWMHYN QTVDIWSVGC IMAELLTGRT LFPGTDHIDQ 
     STHHHHGGGH HHHGTTSS T GHHHHHHHHH HHHHHHHTS  S   STHHHH 

 251 LKLILRLVGT PGAELLKKIS SESARNYIQS LAQMPKMNFA NVFIGANPLA 
     HHHHHHHHT   THHHHHHT  THHHHHHHHH T      TGG GGGGGGGHHH 

 301 VDLLEKMLVL DSDKRITAAQ ALAHAYFAQY HDPDDEPVAD PYDQSFESRD 
     HHHHHHHT S TGGGT THHH HHGGGGGGGT TTGGGT        TGGGGT  

 351 LLIDEWKSLT YDEVISFVPP PLDQEEMES 
      THHHHHHHH HHHHHTT