Subdomain X of Cyclin-Dependent Kinase 2

Subdomain X includes residues 210-254. Although subdomain X is not highly conserved within the kinase family, it is conserved within the cyclin-dependent kinases. It contains the GDSEID motif at the N-terminal end of the alpha-5 helix (helix G in cPKA.)

Between subdomains X and XI is a large insertion. Currently, the importance of this region is unknown.