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Beware of PP1!



Dear kinasers,

regarding the use of PP1, beware, it is not at all as specific as
previously claimed. We have used it and found that inhibits the
platelet-derived growth factor receptors as well as the stem cell factor
receptor/c-kit in the same concentration range as it inhibits Src.
Best regards, Lars Ronnstrand

Lars Rönnstrand, PhD
Ludwig Institute for Cancer Research
Biomedical Center
Box 595
S-751 24 UPPSALA
Sweden
tel. +46-18 16 04 06
fax  +46-18 16 04 20
e-mail  Lars.Ronnstrand@LICR.uu.se
home page: http://www.LICR.uu.se/groups/sigtrans/index.html