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PKA inhibitors



H89 as been describe to be 660 time more effective on PKA than on
PKC.However, on our cells, we only observe about 2 to 5 time differences
between "PKA and PKC dependent" processes! does anyone know a more
selective inhibitor of PKA. We have already tested the myristoylated PKA
inhibitor (14-22) Amide, cell permeable without any success. thank you.


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Gérard Corinne
ICNE- UMR 6544 CNRS
Faculté de Médecine Nord
Boulevard Pierre Dramard
13916 Marseille Cédex 20 France
Tel :(33) 04 91 69 89 03
Fax :(33) 04 91 69 89 20
e-mail : gerard.c@jean-roche.univ.mrs.fr