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Re: p38

Dear All,

A question that has come to mind from Brigitte's query re: the 
correlation (and anomalies) between dual phosphorylation of p38 and 
resultant activity. What is the current concensus regarding whether 
there is a correlation between dual phosphorylation  and activity for 
the Jun kinases and erk1/2 kinases too? We are measuring 
the phosphorylation status of the various MAP kinase family members 
by immunocytochemistry.

Julia Gee

Tenovus Cancer Research Centre, UK